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Items: 1 to 50 of 190

1.

Preventing carbon monoxide poisoning.

Jones SJ, Horton A, Brunt H, Shankar G.

BMJ. 2019 Jul 15;366:l4613. doi: 10.1136/bmj.l4613. No abstract available.

PMID:
31307998
2.

Atezolizumab plus bevacizumab and chemotherapy in non-small-cell lung cancer (IMpower150): key subgroup analyses of patients with EGFR mutations or baseline liver metastases in a randomised, open-label phase 3 trial.

Reck M, Mok TSK, Nishio M, Jotte RM, Cappuzzo F, Orlandi F, Stroyakovskiy D, Nogami N, Rodríguez-Abreu D, Moro-Sibilot D, Thomas CA, Barlesi F, Finley G, Lee A, Coleman S, Deng Y, Kowanetz M, Shankar G, Lin W, Socinski MA; IMpower150 Study Group.

Lancet Respir Med. 2019 May;7(5):387-401. doi: 10.1016/S2213-2600(19)30084-0. Epub 2019 Mar 25.

PMID:
30922878
3.

Chitosan Encapsulation Enhances the Bioavailability and Tissue Retention of Curcumin and Improves its Efficacy in Preventing B[a]P-induced Lung Carcinogenesis.

Vijayakurup V, Thulasidasan AT, Shankar G M, Retnakumari AP, Nandan CD, Somaraj J, Antony J, Alex VV, Vinod BS, Liju VB, Sundaram S, Kumar GSV, Anto RJ.

Cancer Prev Res (Phila). 2019 Apr;12(4):225-236. doi: 10.1158/1940-6207.CAPR-18-0437. Epub 2019 Feb 13.

PMID:
30760502
4.

Immunogenicity of Golimumab and its Clinical Relevance in Patients With Ulcerative Colitis.

Adedokun OJ, Gunn GR 3rd, Leu JH, Gargano C, Xu Z, Sandborn WJ, Rutgeerts P, Shankar G.

Inflamm Bowel Dis. 2019 Feb 8. doi: 10.1093/ibd/izz003. [Epub ahead of print]

PMID:
30753466
5.

Loss of Primary Cilia Drives Switching from Hedgehog to Ras/MAPK Pathway in Resistant Basal Cell Carcinoma.

Kuonen F, Huskey NE, Shankar G, Jaju P, Whitson RJ, Rieger KE, Atwood SX, Sarin KY, Oro AE.

J Invest Dermatol. 2019 Jul;139(7):1439-1448. doi: 10.1016/j.jid.2018.11.035. Epub 2019 Jan 29.

PMID:
30707899
6.

TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.

Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, Li R, Wernig M, Wong WH, Chang HY, Oro AE.

Cell Stem Cell. 2019 Feb 7;24(2):271-284.e8. doi: 10.1016/j.stem.2018.12.012. Epub 2019 Jan 24.

PMID:
30686763
7.

Honey bee Royalactin unlocks conserved pluripotency pathway in mammals.

Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC.

Nat Commun. 2018 Dec 4;9(1):5078. doi: 10.1038/s41467-018-06256-4.

8.

Immunogenicity of golimumab and its clinical relevance in patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

Leu JH, Adedokun OJ, Gargano C, Hsia EC, Xu Z, Shankar G.

Rheumatology (Oxford). 2019 Mar 1;58(3):441-446. doi: 10.1093/rheumatology/key309.

PMID:
30412238
9.

Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment.

Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, Khavari PA, Oro AE.

Nat Genet. 2018 Dec;50(12):1658-1665. doi: 10.1038/s41588-018-0263-0. Epub 2018 Nov 5.

10.

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).

Kowanetz M, Zou W, Gettinger SN, Koeppen H, Kockx M, Schmid P, Kadel EE 3rd, Wistuba I, Chaft J, Rizvi NA, Spigel DR, Spira A, Hirsch FR, Cohen V, Smith D, Boyd Z, Miley N, Flynn S, Leveque V, Shames DS, Ballinger M, Mocci S, Shankar G, Funke R, Hampton G, Sandler A, Amler L, Mellman I, Chen DS, Hegde PS.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10119-E10126. doi: 10.1073/pnas.1802166115. Epub 2018 Oct 8.

11.

CRISPR-Mediated Reorganization of Chromatin Loop Structure.

Morgan SL, Chang EY, Mariano NC, Bermudez A, Arruda NL, Wu F, Luo Y, Shankar G, Huynh SK, Huang CC, Pitteri SJ, Wang KC.

J Vis Exp. 2018 Sep 14;(139). doi: 10.3791/57457.

12.

Postoperative stroke after anterior cervical discectomy and fusion in patients with carotid artery stenosis: a statewide database analysis.

Chughtai M, Sultan AA, Padilla J, Beyer GA, Newman JM, Davidson IU, Ilyas H, Udo-Inyang I Jr, Berger RJ, Samuel LT, Shankar GM, Paulino CB, Pelle D, Savage JW, Steinmetz MP, Mroz TE.

Spine J. 2019 Apr;19(4):597-601. doi: 10.1016/j.spinee.2018.09.011. Epub 2018 Sep 21.

PMID:
30244036
13.
14.

DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome.

Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV, Shankar GM, Penson T, Lastrapes M, Daubner D, Meinhardt M, Hennig S, Kaplan AB, Fujio S, Kuter BM, Bertalan MS, Miller JJ, Batten JM, Ely HA, Christiansen J, Baretton GB, Stemmer-Rachamimov AO, Santagata S, Rivera MN, Barker FG 2nd, Schackert G, Wakimoto H, Iafrate AJ, Carter SL, Cahill DP, Brastianos PK.

Acta Neuropathol. 2018 Nov;136(5):779-792. doi: 10.1007/s00401-018-1899-7. Epub 2018 Aug 19.

PMID:
30123936
15.

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.

16.

Differential sensitivity of chronic high-fat-diet-induced obesity in Sprague-Dawley rats.

Devan SRK, Arumugam S, Shankar G, Poosala S.

J Basic Clin Physiol Pharmacol. 2018 Sep 25;29(5):553-563. doi: 10.1515/jbcpp-2017-0030. No abstract available.

PMID:
30076779
17.

Identification and structural characterization of in vivo metabolites of balofloxacin in rat plasma, urine and feces samples using Q-TOF/LC/ESI/MS/MS : In silico toxicity studies.

Shankar G, Borkar RM, Udutha S, Anagoni SP, Srinivas R.

J Pharm Biomed Anal. 2018 Sep 10;159:200-211. doi: 10.1016/j.jpba.2018.06.050. Epub 2018 Jun 28.

PMID:
29990887
18.

Identification and characterization of stress degradation products of sumatriptan succinate by using LC/Q-TOF-ESI-MS/MS and NMR: Toxicity evaluation of degradation products.

Udutha S, Shankar G, Borkar RM, Kumar K, Srinivasulu G, Guntuku L, Naidu VGM, Srinivas R.

J Mass Spectrom. 2018 Oct;53(10):963-975. doi: 10.1002/jms.4266. Epub 2018 Aug 15.

PMID:
29987857
19.

Portal Annular Pancreas: Case Report of a Rare Anomaly.

Dhanapal B, Shankar G, Krishnaraj B, Govindarajalou R, Ruparelia J, Deivasigamani A, Sistla SC.

Cureus. 2018 Mar 26;10(3):e2366. doi: 10.7759/cureus.2366.

20.

In vitro and in vivo metabolic investigation of the Palbociclib by UHPLC-Q-TOF/MS/MS and in silico toxicity studies of its metabolites.

Chavan BB, Tiwari S, G S, Nimbalkar RD, Garg P, R S, Talluri MVNK.

J Pharm Biomed Anal. 2018 Aug 5;157:59-74. doi: 10.1016/j.jpba.2018.05.008. Epub 2018 May 16.

PMID:
29772457
21.

Liquid chromatography/electrospray ionization tandem mass spectrometry study of repaglinide and its forced degradation products.

Purna Chander C, Raju B, Ramesh M, Shankar G, Srinivas R.

Rapid Commun Mass Spectrom. 2018 Aug 15;32(15):1181-1190. doi: 10.1002/rcm.8151.

PMID:
29723439
22.

Penile Dislocation with Inversion: A Rare Complication of Blunt Pelvic Injury.

Sahadev R, Jadhav V, Munianjanappa NB, Shankar G.

J Indian Assoc Pediatr Surg. 2018 Apr-Jun;23(2):90-92. doi: 10.4103/jiaps.JIAPS_71_17.

23.

The impact of surgery on survival after progression of glioblastoma: A retrospective cohort analysis of a contemporary patient population.

Sastry RA, Shankar GM, Gerstner ER, Curry WT.

J Clin Neurosci. 2018 Jul;53:41-47. doi: 10.1016/j.jocn.2018.04.004. Epub 2018 Apr 19.

PMID:
29680441
24.

Implication of Biomarker Mutations for Predicting Survival in Patients With Metastatic Lung Cancer to the Spine.

Choi BD, Shankar GM, Sivaganesan A, Van Beaver LA, Oh K, Shin JH.

Spine (Phila Pa 1976). 2018 Nov 1;43(21):E1274-E1280. doi: 10.1097/BRS.0000000000002683.

PMID:
29652780
25.

Application of automated liquid handling in ligand-binding assay-based bioanalytical method development: the practical considerations.

Ware M, Shankar G, Breslin P, Yang TY.

Bioanalysis. 2018 Apr 1;10(7):425-430. doi: 10.4155/bio-2017-0212. Epub 2018 Mar 21. No abstract available.

26.

Pd(II)/PhI(OAc)2 promoted direct cross coupling of glucals with aromatic acids.

Begum Z, Shankar G, Sirisha K, Reddy BVS.

Carbohydr Res. 2018 May 22;461:1-3. doi: 10.1016/j.carres.2018.03.002. Epub 2018 Mar 12.

PMID:
29549748
27.

Proposal of degradation pathway with toxicity prediction for hydrolytic and photolytic degradation products of timolol.

Devrukhakar PS, M SS, G S, R S.

J Pharm Biomed Anal. 2018 May 30;154:7-15. doi: 10.1016/j.jpba.2018.02.057. Epub 2018 Feb 28.

PMID:
29524771
28.

Not a Hydrocele!

Hegde S, Jadhav V, Shankar G.

J Pediatr. 2018 Jun;197:311. doi: 10.1016/j.jpeds.2018.01.011. Epub 2018 Mar 1. No abstract available.

PMID:
29502879
29.

Gastric lipoma: a rare cause of haematemesis.

Krishnaraj B, Dhanapal B, Shankar G, Sistla SC, Galidevara I, Suresh A.

Ann R Coll Surg Engl. 2018 Mar;100(3):e41-e43. doi: 10.1308/rcsann.2017.0209. Epub 2018 Feb 27.

30.

A stability-indicating LC-MS/MS method for zidovudine: Identification, characterization and toxicity prediction of two major acid degradation products.

Devrukhakar PS, Shiva Shankar M, Shankar G, Srinivas R.

J Pharm Anal. 2017 Aug;7(4):231-236. doi: 10.1016/j.jpha.2017.01.006. Epub 2017 Jan 18.

31.

Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.

Whitson RJ, Lee A, Urman NM, Mirza A, Yao CY, Brown AS, Li JR, Shankar G, Fry MA, Atwood SX, Lee EY, Hollmig ST, Aasi SZ, Sarin KY, Scott MP, Epstein EH Jr, Tang JY, Oro AE.

Nat Med. 2018 Mar;24(3):271-281. doi: 10.1038/nm.4476. Epub 2018 Feb 5.

32.

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas.

Juratli TA, Thiede C, Koerner MVA, Tummala SS, Daubner D, Shankar GM, Williams EA, Martinez-Lage M, Soucek S, Robel K, Penson T, Krause M, Appold S, Meinhardt M, Pinzer T, Miller JJ, Krex D, Ely HA, Silverman IM, Christiansen J, Schackert G, Wakimoto H, Kirsch M, Brastianos PK, Cahill DP.

Oncotarget. 2017 Nov 24;8(65):109228-109237. doi: 10.18632/oncotarget.22650. eCollection 2017 Dec 12.

33.

Role of synaptophysin in the intraoperative assessment of quadrantic innervation of the proximal doughnut in Hirschsprung disease.

Yadav L, Babu MK, Das K, Mohanty S, Divya P, Shankar G, Kini U.

Natl Med J India. 2017 Jul-Aug;30(4):187-192. doi: 10.4103/0970-258X.218669.

34.

Proteinaceous sperm motility inhibitory factor from the female Indian garden lizard Calotes versicolor.

Shankar G, Uppangala S, Adiga SK, Willard B, Sagar BKC, Titus RSK, Marathe GK.

Reprod Fertil Dev. 2018 May;30(5):744-751. doi: 10.1071/RD17292.

PMID:
29136399
35.

A phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients with advanced non-small cell lung cancer.

Soria JC, Adjei AA, Bahleda R, Besse B, Ferte C, Planchard D, Zhou J, Ware J, Morrissey K, Shankar G, Lin W, Schutzman JL, Dy GK, Groen HJM.

Eur J Cancer. 2017 Nov;86:186-196. doi: 10.1016/j.ejca.2017.08.027. Epub 2017 Oct 6.

PMID:
28992562
36.

Implementing a tiered approach to bioanalytical method validation for large-molecule ligand-binding assay methods in pharmacokinetic assessments.

Watson RG, Clements-Egan A, Schantz A, Ware M, Wu B, Yang TY, Shankar G, Marini JC.

Bioanalysis. 2017 Sep;9(18):1407-1422. doi: 10.4155/bio-2017-0044. Epub 2017 Sep 18.

PMID:
28920457
37.

Liquid biopsy for brain tumors.

Shankar GM, Balaj L, Stott SL, Nahed B, Carter BS.

Expert Rev Mol Diagn. 2017 Oct;17(10):943-947. doi: 10.1080/14737159.2017.1374854. Epub 2017 Sep 6. Review.

38.

A Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of Pictilisib in Combination with Erlotinib in Patients with Advanced Solid Tumors.

Leong S, Moss RA, Bowles DW, Ware JA, Zhou J, Spoerke JM, Lackner MR, Shankar G, Schutzman JL, van der Noll R, Voest EE, Schellens JHM.

Oncologist. 2017 Dec;22(12):1491-1499. doi: 10.1634/theoncologist.2017-0090. Epub 2017 Aug 10.

39.

Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping.

Morgan SL, Mariano NC, Bermudez A, Arruda NL, Wu F, Luo Y, Shankar G, Jia L, Chen H, Hu JF, Hoffman AR, Huang CC, Pitteri SJ, Wang KC.

Nat Commun. 2017 Jul 13;8:15993. doi: 10.1038/ncomms15993.

40.

The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity.

Tateishi K, Higuchi F, Miller JJ, Koerner MVA, Lelic N, Shankar GM, Tanaka S, Fisher DE, Batchelor TT, Iafrate AJ, Wakimoto H, Chi AS, Cahill DP.

Cancer Res. 2017 Aug 1;77(15):4102-4115. doi: 10.1158/0008-5472.CAN-16-2263. Epub 2017 Jun 16.

41.

Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1-Selected Advanced Non-Small-Cell Lung Cancer (BIRCH).

Peters S, Gettinger S, Johnson ML, Jänne PA, Garassino MC, Christoph D, Toh CK, Rizvi NA, Chaft JE, Carcereny Costa E, Patel JD, Chow LQM, Koczywas M, Ho C, Früh M, van den Heuvel M, Rothenstein J, Reck M, Paz-Ares L, Shepherd FA, Kurata T, Li Z, Qiu J, Kowanetz M, Mocci S, Shankar G, Sandler A, Felip E.

J Clin Oncol. 2017 Aug 20;35(24):2781-2789. doi: 10.1200/JCO.2016.71.9476. Epub 2017 Jun 13.

42.

Forced degradation studies of lansoprazole using LC-ESI HRMS and 1 H-NMR experiments: in vitro toxicity evaluation of major degradation products.

Shankar G, Borkar RM, Suresh U, Guntuku L, Naidu VGM, Nagesh N, Srinivas R.

J Mass Spectrom. 2017 Jul;52(7):459-471. doi: 10.1002/jms.3949.

PMID:
28544042
43.

BAP1 mutations in high-grade meningioma: implications for patient care.

Shankar GM, Santagata S.

Neuro Oncol. 2017 Oct 19;19(11):1447-1456. doi: 10.1093/neuonc/nox094. Review.

44.

The role of revision surgery and adjuvant therapy following subtotal resection of osteosarcoma of the spine: a systematic review with meta-analysis.

Shankar GM, Clarke MJ, Ailon T, Rhines LD, Patel SR, Sahgal A, Laufer I, Chou D, Bilsky MH, Sciubba DM, Fehlings MG, Fisher CG, Gokaslan ZL, Shin JH.

J Neurosurg Spine. 2017 Jul;27(1):97-104. doi: 10.3171/2016.12.SPINE16995. Epub 2017 Apr 28. Review.

PMID:
28452631
45.

Electronic medical records in humanitarian emergencies - the development of an Ebola clinical information and patient management system.

Jobanputra K, Greig J, Shankar G, Perakslis E, Kremer R, Achar J, Gayton I.

Version 3. F1000Res. 2016 Jun 23 [revised 2017 Jan 1];5:1477. doi: 10.12688/f1000research.8287.3. eCollection 2016.

46.

Retroperitoneal Necrotizing Fasciitis Masquerading as Perianal Abscess - Rare and Perilous.

Amaranathan A, Sahoo AK, Barathi D, Shankar G, Sistla SC.

Cureus. 2017 Jan 17;9(1):e982. doi: 10.7759/cureus.982.

47.

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.

Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, Batchelor TT, Ligon KL, Ligon AH, Meyerson M, Dunn IF, Beroukhim R, Louis DN, Perry A, Carter SL, Giannini C, Curry WT Jr, Cahill DP, Barker FG 2nd, Brastianos PK, Santagata S.

Neuro Oncol. 2017 Apr 1;19(4):535-545. doi: 10.1093/neuonc/now235.

48.

Management of Bilateral Wilms' Tumor: Our Experience.

Raghunath Bv, Jadhav V, Shankar G, Narendrababu M, Ramesh S.

Indian J Surg Oncol. 2017 Mar;8(1):4-8. doi: 10.1007/s13193-016-0552-y. Epub 2016 Sep 1.

49.

A study of cognitive fatigue in Multiple Sclerosis with novel clinical and electrophysiological parameters utilizing the event related potential P300.

Chinnadurai SA, Venkatesan SA, Shankar G, Samivel B, Ranganathan LN.

Mult Scler Relat Disord. 2016 Nov;10:1-6. doi: 10.1016/j.msard.2016.08.001. Epub 2016 Aug 8.

PMID:
27919474
50.

Effect of Immunotherapy Status on Outcomes in Patients With Metastatic Melanoma to the Spine.

Shankar GM, Choi BD, Grannan BL, Oh K, Shin JH.

Spine (Phila Pa 1976). 2017 Jun 15;42(12):E721-E725. doi: 10.1097/BRS.0000000000001993.

PMID:
27879568

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