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Items: 26


Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2).

de Heuvel E, Singh AK, Boronat P, Kooistra AJ, van der Meer T, Sadek P, Blaazer AR, Shaner NC, Bindels DS, Caljon G, Maes L, Sterk GJ, Siderius M, Oberholzer M, de Esch IJP, Brown DG, Leurs R.

Bioorg Med Chem. 2019 Sep 15;27(18):4013-4029. doi: 10.1016/j.bmc.2019.06.026. Epub 2019 Jul 5.


Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling.

Hong SR, Wang CL, Huang YS, Chang YC, Chang YC, Pusapati GV, Lin CY, Hsu N, Cheng HC, Chiang YC, Huang WE, Shaner NC, Rohatgi R, Inoue T, Lin YC.

Nat Commun. 2018 Apr 30;9(1):1732. doi: 10.1038/s41467-018-03952-z.


Characterization of a spectrally diverse set of fluorescent proteins as FRET acceptors for mTurquoise2.

Mastop M, Bindels DS, Shaner NC, Postma M, Gadella TWJ Jr, Goedhart J.

Sci Rep. 2017 Sep 20;7(1):11999. doi: 10.1038/s41598-017-12212-x.


Blue-Shifted Green Fluorescent Protein Homologues Are Brighter than Enhanced Green Fluorescent Protein under Two-Photon Excitation.

Molina RS, Tran TM, Campbell RE, Lambert GG, Salih A, Shaner NC, Hughes TE, Drobizhev M.

J Phys Chem Lett. 2017 Jun 15;8(12):2548-2554. doi: 10.1021/acs.jpclett.7b00960. Epub 2017 May 25.


Engineering of mCherry variants with long Stokes shift, red-shifted fluorescence, and low cytotoxicity.

Shen Y, Chen Y, Wu J, Shaner NC, Campbell RE.

PLoS One. 2017 Feb 27;12(2):e0171257. doi: 10.1371/journal.pone.0171257. eCollection 2017.


Structural analysis of the bright monomeric yellow-green fluorescent protein mNeonGreen obtained by directed evolution.

Clavel D, Gotthard G, von Stetten D, De Sanctis D, Pasquier H, Lambert GG, Shaner NC, Royant A.

Acta Crystallogr D Struct Biol. 2016 Dec 1;72(Pt 12):1298-1307. Epub 2016 Nov 30.


New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories.

Tewson PH, Martinka S, Shaner NC, Hughes TE, Quinn AM.

J Biomol Screen. 2016 Mar;21(3):298-305. doi: 10.1177/1087057115618608. Epub 2015 Dec 11.


Occurrence of Isopenicillin-N-Synthase Homologs in Bioluminescent Ctenophores and Implications for Coelenterazine Biosynthesis.

Francis WR, Shaner NC, Christianson LM, Powers ML, Haddock SH.

PLoS One. 2015 Jun 30;10(6):e0128742. doi: 10.1371/journal.pone.0128742. eCollection 2015.


Fluorescent proteins for quantitative microscopy: important properties and practical evaluation.

Shaner NC.

Methods Cell Biol. 2014;123:95-111. doi: 10.1016/B978-0-12-420138-5.00006-9.


A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum.

Shaner NC, Lambert GG, Chammas A, Ni Y, Cranfill PJ, Baird MA, Sell BR, Allen JR, Day RN, Israelsson M, Davidson MW, Wang J.

Nat Methods. 2013 May;10(5):407-9. doi: 10.1038/nmeth.2413. Epub 2013 Mar 24.


A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly.

Francis WR, Christianson LM, Kiko R, Powers ML, Shaner NC, Haddock SH.

BMC Genomics. 2013 Mar 12;14:167. doi: 10.1186/1471-2164-14-167.


Expression and characterization of the calcium-activated photoprotein from the ctenophore Bathocyroe fosteri: insights into light-sensitive photoproteins.

Powers ML, McDermott AG, Shaner NC, Haddock SH.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):360-6. doi: 10.1016/j.bbrc.2012.12.026. Epub 2012 Dec 19. Erratum in: Biochem Biophys Res Commun. 2013 Jun 14;435(4):751.


The mFruit collection of monomeric fluorescent proteins.

Shaner NC.

Clin Chem. 2013 Feb;59(2):440-1. doi: 10.1373/clinchem.2012.194837. Epub 2012 Dec 4. No abstract available.


Concurrent imaging of synaptic vesicle recycling and calcium dynamics.

Li H, Foss SM, Dobryy YL, Park CK, Hires SA, Shaner NC, Tsien RY, Osborne LC, Voglmaier SM.

Front Mol Neurosci. 2011 Nov 2;4:34. doi: 10.3389/fnmol.2011.00034. eCollection 2011.


A monomeric photoconvertible fluorescent protein for imaging of dynamic protein localization.

Hoi H, Shaner NC, Davidson MW, Cairo CW, Wang J, Campbell RE.

J Mol Biol. 2010 Sep 3;401(5):776-91. doi: 10.1016/j.jmb.2010.06.056. Epub 2010 Jul 13.


Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer.

Ouyang M, Huang H, Shaner NC, Remacle AG, Shiryaev SA, Strongin AY, Tsien RY, Wang Y.

Cancer Res. 2010 Mar 15;70(6):2204-12. doi: 10.1158/0008-5472.CAN-09-3698. Epub 2010 Mar 2.


Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals.

Lin MZ, McKeown MR, Ng HL, Aguilera TA, Shaner NC, Campbell RE, Adams SR, Gross LA, Ma W, Alber T, Tsien RY.

Chem Biol. 2009 Nov 25;16(11):1169-79. doi: 10.1016/j.chembiol.2009.10.009.


Improving the photostability of bright monomeric orange and red fluorescent proteins.

Shaner NC, Lin MZ, McKeown MR, Steinbach PA, Hazelwood KL, Davidson MW, Tsien RY.

Nat Methods. 2008 Jun;5(6):545-51. doi: 10.1038/nmeth.1209. Epub 2008 May 4.


Advances in fluorescent protein technology.

Shaner NC, Patterson GH, Davidson MW.

J Cell Sci. 2007 Dec 15;120(Pt 24):4247-60. Review. Erratum in: J Cell Sci. 2011 Jul 1;124(Pt 13):2321.


Exploration of new chromophore structures leads to the identification of improved blue fluorescent proteins.

Ai HW, Shaner NC, Cheng Z, Tsien RY, Campbell RE.

Biochemistry. 2007 May 22;46(20):5904-10. Epub 2007 Apr 20.


Novel chromophores and buried charges control color in mFruits.

Shu X, Shaner NC, Yarbrough CA, Tsien RY, Remington SJ.

Biochemistry. 2006 Aug 15;45(32):9639-47.


A guide to choosing fluorescent proteins.

Shaner NC, Steinbach PA, Tsien RY.

Nat Methods. 2005 Dec;2(12):905-9. Review.


Actin and alpha-actinin dynamics in the adhesion and motility of EPEC and EHEC on host cells.

Shaner NC, Sanger JW, Sanger JM.

Cell Motil Cytoskeleton. 2005 Feb;60(2):104-20.


Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein.

Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AE, Tsien RY.

Nat Biotechnol. 2004 Dec;22(12):1567-72. Epub 2004 Nov 21.


Myofibrillogenesis in skeletal muscle cells.

Sanger JW, Chowrashi P, Shaner NC, Spalthoff S, Wang J, Freeman NL, Sanger JM.

Clin Orthop Relat Res. 2002 Oct;(403 Suppl):S153-62. Review.


Expression of green or red fluorescent protein (GFP or DsRed) linked proteins in nonmuscle and muscle cells.

Ayoob JC, Shaner NC, Sanger JW, Sanger JM.

Mol Biotechnol. 2001 Jan;17(1):65-71.


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