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Accurate and Efficient Plate and Rod Micro Finite Element Whole Bone Models Based on High-Resolution Peripheral Computed Tomography.

Wang J, Zhou B, Hu Y, Zhang Z, Yu YE, Nawathe S, Nishiyama KK, Keaveny TM, Shane E, Guo XE.

J Biomech Eng. 2019 Jan 31. doi: 10.1115/1.4042680. [Epub ahead of print]


A Randomized Placebo-Controlled Trial of Low- Versus Moderate-Dose Vitamin D3 Supplementation on Bone Mineral Density in Postmenopausal Women With HIV.

Yin MT, RoyChoudhury A, Bucovsky M, Colon I, Ferris DC, Olender S, Agarwal S, Sharma A, Zeana C, Zingman B, Shane E.

J Acquir Immune Defic Syndr. 2019 Mar 1;80(3):342-349. doi: 10.1097/QAI.0000000000001929.


Improving fracture risk assessment in older adults.

Shane E.

Lancet Diabetes Endocrinol. 2019 Jan;7(1):5-7. doi: 10.1016/S2213-8587(18)30333-4. Epub 2018 Nov 28. No abstract available.


Disrupted radial and tibial microarchitecture in patients with monoclonal gammopathy of undetermined significance.

Stein EM, Dash A, Bucovsky M, Agarwal S, Fu J, Lentzsch S, Shane E.

Osteoporos Int. 2019 Mar;30(3):629-635. doi: 10.1007/s00198-018-4787-z. Epub 2018 Nov 28.


Resistance Training Reduces Skeletal Muscle Work Efficiency in Weight-Reduced and Non-Weight-Reduced Subjects.

Rosenbaum M, Heaner M, Goldsmith RL, Christian Schulze P, Shukla A, Shen W, Shane EJ, Naor E, Leibel RL, Aronne LJ.

Obesity (Silver Spring). 2018 Oct;26(10):1576-1583. doi: 10.1002/oby.22274. Epub 2018 Sep 27.


Correction to: Differences in bone quality and strength between Asian and Caucasian young men.

Kepley AL, Nishiyama KK, Zhou B, Wang J, Zhang C, McMahon DJ, Foley KF, Walker MD, Guo XE, Shane E, Nickolas TL.

Osteoporos Int. 2018 Nov;29(11):2581. doi: 10.1007/s00198-018-4684-5.


Survey of Machine Learning Techniques in Drug Discovery.

Stephenson N, Shane E, Chase J, Rowland J, Ries D, Justice N, Zhang J, Chan L, Cao R.

Curr Drug Metab. 2019;20(3):185-193. doi: 10.2174/1389200219666180820112457.


Current Understanding of Epidemiology, Pathophysiology, and Management of Atypical Femur Fractures.

Starr J, Tay YKD, Shane E.

Curr Osteoporos Rep. 2018 Aug;16(4):519-529. doi: 10.1007/s11914-018-0464-6. Review.


Abnormal microarchitecture and stiffness in postmenopausal women using chronic inhaled glucocorticoids.

Liu Y, Dimango E, Bucovsky M, Agarwal S, Nishiyama K, Guo XE, Shane E, Stein EM.

Osteoporos Int. 2018 Sep;29(9):2121-2127. doi: 10.1007/s00198-018-4591-9. Epub 2018 Jun 11.


Bone density and microarchitecture in hepatitis C and HIV-coinfected postmenopausal minority women.

T Yin M, RoyChoudhury A, Nishiyama K, Lang T, Shah J, Olender S, Ferris DC, Zeana C, Sharma A, Zingman B, Bucovsky M, Colon I, Shane E.

Osteoporos Int. 2018 Apr;29(4):871-879. doi: 10.1007/s00198-017-4354-z. Epub 2018 Feb 1.


Adults with cystic fibrosis have deficits in bone structure and strength at the distal tibia despite similar size and measuring standard and relative sites.

Nishiyama KK, Agarwal S, Kepley A, Rosete F, Hu Y, Guo XE, Keating CL, DiMango EA, Shane E.

Bone. 2018 Feb;107:181-187. doi: 10.1016/j.bone.2017.11.006. Epub 2017 Nov 14.


Subchondral Trabecular Rod Loss and Plate Thickening in the Development of Osteoarthritis.

Chen Y, Hu Y, Yu YE, Zhang X, Watts T, Zhou B, Wang J, Wang T, Zhao W, Chiu KY, Leung FK, Cao X, Macaulay W, Nishiyama KK, Shane E, Lu WW, Guo XE.

J Bone Miner Res. 2018 Feb;33(2):316-327. doi: 10.1002/jbmr.3313. Epub 2017 Nov 16.


Response to Stoecker et al.

Khosla S, Shane E.

J Bone Miner Res. 2017 Jun;32(6):1388. doi: 10.1002/jbmr.3144. Epub 2017 May 2. No abstract available.


Spine Trabecular Bone Score as an Indicator of Bone Microarchitecture at the Peripheral Skeleton in Kidney Transplant Recipients.

Luckman M, Hans D, Cortez N, Nishiyama KK, Agarawal S, Zhang C, Nikkel L, Iyer S, Fusaro M, Guo EX, McMahon DJ, Shane E, Nickolas TL.

Clin J Am Soc Nephrol. 2017 Apr 3;12(4):644-652. doi: 10.2215/CJN.09850916. Epub 2017 Mar 27.


IGF-1 Receptor Expression on Circulating Osteoblast Progenitor Cells Predicts Tissue-Based Bone Formation Rate and Response to Teriparatide in Premenopausal Women With Idiopathic Osteoporosis.

Cohen A, Kousteni S, Bisikirska B, Shah JG, Manavalan JS, Recker RR, Lappe J, Dempster DW, Zhou H, McMahon DJ, Bucovsky M, Kamanda-Kosseh M, Stubby J, Shane E.

J Bone Miner Res. 2017 Jun;32(6):1267-1273. doi: 10.1002/jbmr.3109. Epub 2017 Mar 23.


Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward.

Khosla S, Cauley JA, Compston J, Kiel DP, Rosen C, Saag KG, Shane E.

J Bone Miner Res. 2017 Mar;32(3):424-430. doi: 10.1002/jbmr.3074. Epub 2016 Dec 29.


Frailty in Postmenopausal African American and Hispanic HIV-Infected Women.

Young P, Shah J, Zhang C, Ferris DC, Colon I, Bucovsky M, Punyanitya M, McMahon DJ, Shane E, Yin MT.

J Frailty Aging. 2016;5(4):242-246.


Differences in bone quality and strength between Asian and Caucasian young men.

Kepley AL, Nishiyama KK, Zhou B, Wang J, Zhang C, McMahon DJ, Foley KF, Walker MD, Edward Guo X, Shane E, Nickolas TL.

Osteoporos Int. 2017 Feb;28(2):549-558. doi: 10.1007/s00198-016-3762-9. Epub 2016 Sep 16. Erratum in: Osteoporos Int. 2018 Nov;29(11):2581.


Cardiovascular Risk in HIV-Infected and Uninfected Postmenopausal Minority Women: Use of the Framingham Risk Score.

Cortés YI, Reame N, Zeana C, Jia H, Ferris DC, Shane E, Yin MT.

J Womens Health (Larchmt). 2017 Mar;26(3):241-248. doi: 10.1089/jwh.2015.5736. Epub 2016 Sep 9.


Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training.

Bonaretti S, Vilayphiou N, Chan CM, Yu A, Nishiyama K, Liu D, Boutroy S, Ghasem-Zadeh A, Boyd SK, Chapurlat R, McKay H, Shane E, Bouxsein ML, Black DM, Majumdar S, Orwoll ES, Lang TF, Khosla S, Burghardt AJ.

Osteoporos Int. 2017 Jan;28(1):245-257. doi: 10.1007/s00198-016-3705-5. Epub 2016 Jul 30.


Exploring gaps in surveillance of a small measles outbreak in Toronto, Canada.

Gournis E, Shane A, Shane E, Arthur A, Berger L.

Can Commun Dis Rep. 2016 Jul 7;42(7):146-148. eCollection 2016 Jul 7.


A Crisis in the Treatment of Osteoporosis.

Khosla S, Shane E.

J Bone Miner Res. 2016 Aug;31(8):1485-7. doi: 10.1002/jbmr.2888. Epub 2016 Jun 28. No abstract available.


In Vivo Precision of Digital Topological Skeletonization Based Individual Trabecula Segmentation (ITS) Analysis of Trabecular Microstructure at the Distal Radius and Tibia by HR-pQCT.

Zhou B, Zhang Z, Wang J, Yu YE, Liu XS, Nishiyama KK, Rubin MR, Shane E, Bilezikian JP, Guo XE.

Pattern Recognit Lett. 2016 Jun 1;76:83-89. Epub 2015 Apr 1.


In vivo assessment of bone structure and estimated bone strength by first- and second-generation HR-pQCT.

Agarwal S, Rosete F, Zhang C, McMahon DJ, Guo XE, Shane E, Nishiyama KK.

Osteoporos Int. 2016 Oct;27(10):2955-66. doi: 10.1007/s00198-016-3621-8. Epub 2016 May 7.


Deterioration of trabecular plate-rod and cortical microarchitecture and reduced bone stiffness at distal radius and tibia in postmenopausal women with vertebral fractures.

Wang J, Stein EM, Zhou B, Nishiyama KK, Yu YE, Shane E, Guo XE.

Bone. 2016 Jul;88:39-46. doi: 10.1016/j.bone.2016.04.003. Epub 2016 Apr 12.


High-resolution peripheral quantitative computed tomography (HR-pQCT) can assess microstructural and biomechanical properties of both human distal radius and tibia: Ex vivo computational and experimental validations.

Zhou B, Wang J, Yu YE, Zhang Z, Nawathe S, Nishiyama KK, Rosete FR, Keaveny TM, Shane E, Guo XE.

Bone. 2016 May;86:58-67. doi: 10.1016/j.bone.2016.02.016. Epub 2016 Feb 26.


Microarchitecture and Peripheral BMD are Impaired in Postmenopausal White Women With Fracture Independently of Total Hip T-Score: An International Multicenter Study.

Boutroy S, Khosla S, Sornay-Rendu E, Zanchetta MB, McMahon DJ, Zhang CA, Chapurlat RD, Zanchetta J, Stein EM, Bogado C, Majumdar S, Burghardt AJ, Shane E.

J Bone Miner Res. 2016 Jun;31(6):1158-66. doi: 10.1002/jbmr.2796.


Bone Density After Teriparatide Discontinuation in Premenopausal Idiopathic Osteoporosis.

Cohen A, Kamanda-Kosseh M, Recker RR, Lappe JM, Dempster DW, Zhou H, Cremers S, Bucovsky M, Stubby J, Shane E.

J Clin Endocrinol Metab. 2015 Nov;100(11):4208-14. doi: 10.1210/jc.2015-2829. Epub 2015 Sep 10.


Aging Versus Postmenopausal Osteoporosis: Bone Composition and Maturation Kinetics at Actively-Forming Trabecular Surfaces of Female Subjects Aged 1 to 84 Years.

Paschalis EP, Fratzl P, Gamsjaeger S, Hassler N, Brozek W, Eriksen EF, Rauch F, Glorieux FH, Shane E, Dempster D, Cohen A, Recker R, Klaushofer K.

J Bone Miner Res. 2016 Feb;31(2):347-57. doi: 10.1002/jbmr.2696. Epub 2015 Sep 23.


Subtle changes in bone mineralization density distribution in most severely affected patients with chronic obstructive pulmonary disease.

Misof BM, Roschger P, Jorgetti V, Klaushofer K, Borba VZ, Boguszewski CL, Cohen A, Shane E, Zhou H, Dempster DW, Moreira CA.

Bone. 2015 Oct;79:1-7. doi: 10.1016/j.bone.2015.05.018. Epub 2015 May 21.


Marrow adiposity assessed on transiliac crest biopsy samples correlates with noninvasive measurement of marrow adiposity by proton magnetic resonance spectroscopy ((1)H-MRS) at the spine but not the femur.

Cohen A, Shen W, Dempster DW, Zhou H, Recker RR, Lappe JM, Kepley A, Kamanda-Kosseh M, Bucovsky M, Stein EM, Nickolas TL, Shane E.

Osteoporos Int. 2015 Oct;26(10):2471-8. doi: 10.1007/s00198-015-3161-7. Epub 2015 May 19.


Abnormal Skeletal Strength and Microarchitecture in Women With Celiac Disease.

Stein EM, Rogers H, Leib A, McMahon DJ, Young P, Nishiyama K, Guo XE, Lewis S, Green PH, Shane E.

J Clin Endocrinol Metab. 2015 Jun;100(6):2347-53. doi: 10.1210/jc.2015-1392. Epub 2015 Apr 13.


Update on osteoporosis from the 2014 Santa Fe Bone symposium.

Lewiecki EM, Bilezikian JP, Binkley N, Hans D, Krueger D, Miller PD, Oates M, Shane E.

Endocr Res. 2015;40(2):106-19. doi: 10.3109/07435800.2015.1005746. Epub 2015 Mar 24.


Low-Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial.

Kiel DP, Hannan MT, Barton BA, Bouxsein ML, Sisson E, Lang T, Allaire B, Dewkett D, Carroll D, Magaziner J, Shane E, Leary ET, Zimmerman S, Rubin CT.

J Bone Miner Res. 2015 Jul;30(7):1319-28. doi: 10.1002/jbmr.2448.


Vitamin D-related gene polymorphisms, plasma 25-hydroxyvitamin D, and breast cancer risk.

Reimers LL, Crew KD, Bradshaw PT, Santella RM, Steck SE, Sirosh I, Terry MB, Hershman DL, Shane E, Cremers S, Dworakowski E, Teitelbaum SL, Neugut AI, Gammon MD.

Cancer Causes Control. 2015 Feb;26(2):187-203. doi: 10.1007/s10552-014-0497-9. Epub 2014 Nov 25.


Longitudinal HR-pQCT and image registration detects endocortical bone loss in kidney transplantation patients.

Nishiyama KK, Pauchard Y, Nikkel LE, Iyer S, Zhang C, McMahon DJ, Cohen D, Boyd SK, Shane E, Nickolas TL.

J Bone Miner Res. 2015 Mar;30(3):554-61. doi: 10.1002/jbmr.2358.


Relationship of bone mineralization density distribution (BMDD) in cortical and cancellous bone within the iliac crest of healthy premenopausal women.

Misof BM, Dempster DW, Zhou H, Roschger P, Fratzl-Zelman N, Fratzl P, Silverberg SJ, Shane E, Cohen A, Stein E, Nickolas TL, Recker RR, Lappe J, Bilezikian JP, Klaushofer K.

Calcif Tissue Int. 2014 Oct;95(4):332-9. doi: 10.1007/s00223-014-9901-4. Epub 2014 Aug 19.


Skeletal structure in postmenopausal women with osteopenia and fractures is characterized by abnormal trabecular plates and cortical thinning.

Stein EM, Kepley A, Walker M, Nickolas TL, Nishiyama K, Zhou B, Liu XS, McMahon DJ, Zhang C, Boutroy S, Cosman F, Nieves J, Guo XE, Shane E.

J Bone Miner Res. 2014;29(5):1101-9.


Teriparatide increases strength of the peripheral skeleton in premenopausal women with idiopathic osteoporosis: a pilot HR-pQCT study.

Nishiyama KK, Cohen A, Young P, Wang J, Lappe JM, Guo XE, Dempster DW, Recker RR, Shane E.

J Clin Endocrinol Metab. 2014 Jul;99(7):2418-25. doi: 10.1210/jc.2014-1041. Epub 2014 Mar 31.


Kidney transplantation with early corticosteroid withdrawal: paradoxical effects at the central and peripheral skeleton.

Iyer SP, Nikkel LE, Nishiyama KK, Dworakowski E, Cremers S, Zhang C, McMahon DJ, Boutroy S, Liu XS, Ratner LE, Cohen DJ, Guo XE, Shane E, Nickolas TL.

J Am Soc Nephrol. 2014 Jun;25(6):1331-41. doi: 10.1681/ASN.2013080851. Epub 2014 Feb 7.


Bone density, microarchitecture and stiffness in Caucasian and Caribbean Hispanic postmenopausal American women.

Zhou B, Wang J, Stein EM, Zhang Z, Nishiyama KK, Zhang CA, Nickolas TL, Shane E, Guo XE.

Bone Res. 2014 Sep 16;2:14016. doi: 10.1038/boneres.2014.16. eCollection 2014.


Evaluation and management of the premenopausal woman with low BMD.

Cohen A, Shane E.

Curr Osteoporos Rep. 2013 Dec;11(4):276-85. doi: 10.1007/s11914-013-0161-4.


Lower peak bone mass and abnormal trabecular and cortical microarchitecture in young men infected with HIV early in life.

Yin MT, Lund E, Shah J, Zhang CA, Foca M, Neu N, Nishiyama KK, Zhou B, Guo XE, Nelson J, Bell DL, Shane E, Arpadi SM.

AIDS. 2014 Jan 28;28(3):345-53. doi: 10.1097/QAD.0000000000000070.


Premenopausal bone health: osteoporosis in premenopausal women.

Abraham A, Cohen A, Shane E.

Clin Obstet Gynecol. 2013 Dec;56(4):722-9. doi: 10.1097/GRF.0b013e3182a8ae55. Review.


Vitamin D Deficiency Is Prevalent in Morbidly Obese Adolescents Prior to Bariatric Surgery.

Censani M, Stein EM, Shane E, Oberfield SE, McMahon DJ, Lerner S, Fennoy I.

ISRN Obes. 2013;2013. pii: 284516.


Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research.

Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster DW, Ebeling PR, Einhorn TA, Genant HK, Geusens P, Klaushofer K, Lane JM, McKiernan F, McKinney R, Ng A, Nieves J, O'Keefe R, Papapoulos S, Howe TS, van der Meulen MC, Weinstein RS, Whyte MP.

J Bone Miner Res. 2014 Jan;29(1):1-23. doi: 10.1002/jbmr.1998. Epub 2013 Oct 1. Review.


Teriparatide for idiopathic osteoporosis in premenopausal women: a pilot study.

Cohen A, Stein EM, Recker RR, Lappe JM, Dempster DW, Zhou H, Cremers S, McMahon DJ, Nickolas TL, Müller R, Zwahlen A, Young P, Stubby J, Shane E.

J Clin Endocrinol Metab. 2013 May;98(5):1971-81. doi: 10.1210/jc.2013-1172. Epub 2013 Mar 29.


Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study.

Cohen A, Dempster DW, Recker RR, Lappe JM, Zhou H, Zwahlen A, Müller R, Zhao B, Guo X, Lang T, Saeed I, Liu XS, Guo XE, Cremers S, Rosen CJ, Stein EM, Nickolas TL, McMahon DJ, Young P, Shane E.

J Clin Endocrinol Metab. 2013 Jun;98(6):2562-72. doi: 10.1210/jc.2013-1047. Epub 2013 Mar 20.


Clinical imaging of bone microarchitecture with HR-pQCT.

Nishiyama KK, Shane E.

Curr Osteoporos Rep. 2013 Jun;11(2):147-55. doi: 10.1007/s11914-013-0142-7. Review.

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