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Items: 1 to 50 of 550

1.

Low-dose CT imaging of the acute abdomen using model-based iterative reconstruction: a prospective study.

Moloney F, James K, Twomey M, Ryan D, Grey TM, Downes A, Kavanagh RG, Moore N, Murphy MJ, Bye J, Carey BW, McSweeney SE, Deasy C, Andrews E, Shanahan F, Maher MM, O'Connor OJ.

Emerg Radiol. 2018 Nov 17. doi: 10.1007/s10140-018-1658-z. [Epub ahead of print]

PMID:
30448900
2.

Dietary Fiber and Gastrointestinal Disease: an Evolving Story.

O'Grady J, Shanahan F.

Curr Gastroenterol Rep. 2018 Nov 8;20(12):59. doi: 10.1007/s11894-018-0667-0. Review. No abstract available.

PMID:
30406857
3.

A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation.

O'Connell Motherway M, Houston A, O'Callaghan G, Reunanen J, O'Brien F, O'Driscoll T, Casey PG, de Vos WM, van Sinderen D, Shanahan F.

Mol Microbiol. 2018 Oct 23. doi: 10.1111/mmi.14155. [Epub ahead of print]

PMID:
30352131
4.

Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors.

Yen I, Shanahan F, Merchant M, Orr C, Hunsaker T, Durk M, La H, Zhang X, Martin SE, Lin E, Chan J, Yu Y, Amin D, Neve RM, Gustafson A, Venkatanarayan A, Foster SA, Rudolph J, Klijn C, Malek S.

Cancer Cell. 2018 Oct 8;34(4):611-625.e7. doi: 10.1016/j.ccell.2018.09.002.

PMID:
30300582
5.

Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection.

Brown JR, Flemer B, Joyce SA, Zulquernain A, Sheehan D, Shanahan F, O'Toole PW.

BMC Gastroenterol. 2018 Aug 28;18(1):131. doi: 10.1186/s12876-018-0860-5.

6.

The Use of a Mini-Bioreactor Fermentation System as a Reproducible, High-Throughput ex vivo Batch Model of the Distal Colon.

O'Donnell MM, Rea MC, Shanahan F, Ross RP.

Front Microbiol. 2018 Aug 10;9:1844. doi: 10.3389/fmicb.2018.01844. eCollection 2018.

7.

Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut.

O'Connell Motherway M, O'Brien F, O'Driscoll T, Casey PG, Shanahan F, van Sinderen D.

Sci Rep. 2018 Jul 13;8(1):10627. doi: 10.1038/s41598-018-29034-0.

8.

Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice.

Stilling RM, Moloney GM, Ryan FJ, Hoban AE, Bastiaanssen TF, Shanahan F, Clarke G, Claesson MJ, Dinan TG, Cryan JF.

Elife. 2018 May 29;7. pii: e33070. doi: 10.7554/eLife.33070.

9.

A Prospective Metagenomic and Metabolomic Analysis of the Impact of Exercise and/or Whey Protein Supplementation on the Gut Microbiome of Sedentary Adults.

Cronin O, Barton W, Skuse P, Penney NC, Garcia-Perez I, Murphy EF, Woods T, Nugent H, Fanning A, Melgar S, Falvey EC, Holmes E, Cotter PD, O'Sullivan O, Molloy MG, Shanahan F.

mSystems. 2018 Apr 24;3(3). pii: e00044-18. doi: 10.1128/mSystems.00044-18. eCollection 2018 May-Jun.

10.

Publisher Correction: Enterotypes in the landscape of gut microbial community composition.

Costea PI, Hildebrand F, Arumugam M, Bäckhed F, Blaser MJ, Bushman FD, de Vos WM, Ehrlich SD, Fraser CM, Hattori M, Huttenhower C, Jeffery IB, Knights D, Lewis JD, Ley RE, Ochman H, O'Toole PW, Quince C, Relman DA, Shanahan F, Sunagawa S, Wang J, Weinstock GM, Wu GD, Zeller G, Zhao L, Raes J, Knight R, Bork P.

Nat Microbiol. 2018 Mar;3(3):388. doi: 10.1038/s41564-018-0114-x.

PMID:
29440750
11.

Tumour-associated and non-tumour-associated microbiota: Addendum.

Flemer B, Herlihy M, O'Riordain M, Shanahan F, O'Toole PW.

Gut Microbes. 2018 Jul 4;9(4):369-373. doi: 10.1080/19490976.2018.1435246. Epub 2018 Apr 13.

PMID:
29420132
12.

How to swim with sharks: a perspective on Voltaire Cousteau's primer.

Shanahan F.

QJM. 2019 Jan 1;112(1):61-62. doi: 10.1093/qjmed/hcy027. No abstract available.

PMID:
29415122
13.

Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn's Disease and Ulcerative Colitis.

Laserna-Mendieta EJ, Clooney AG, Carretero-Gomez JF, Moran C, Sheehan D, Nolan JA, Hill C, Gahan CGM, Joyce SA, Shanahan F, Claesson MJ.

J Crohns Colitis. 2018 Jan 24;12(2):204-216. doi: 10.1093/ecco-jcc/jjx137.

PMID:
29373727
14.

Inclusion of the Mesentery in Ileocolic Resection for Crohn's Disease is Associated With Reduced Surgical Recurrence.

Coffey CJ, Kiernan MG, Sahebally SM, Jarrar A, Burke JP, Kiely PA, Shen B, Waldron D, Peirce C, Moloney M, Skelly M, Tibbitts P, Hidayat H, Faul PN, Healy V, O'Leary PD, Walsh LG, Dockery P, O'Connell RP, Martin ST, Shanahan F, Fiocchi C, Dunne CP.

J Crohns Colitis. 2018 Nov 9;12(10):1139-1150. doi: 10.1093/ecco-jcc/jjx187.

15.

Enterotypes in the landscape of gut microbial community composition.

Costea PI, Hildebrand F, Arumugam M, Bäckhed F, Blaser MJ, Bushman FD, de Vos WM, Ehrlich SD, Fraser CM, Hattori M, Huttenhower C, Jeffery IB, Knights D, Lewis JD, Ley RE, Ochman H, O'Toole PW, Quince C, Relman DA, Shanahan F, Sunagawa S, Wang J, Weinstock GM, Wu GD, Zeller G, Zhao L, Raes J, Knight R, Bork P.

Nat Microbiol. 2018 Jan;3(1):8-16. doi: 10.1038/s41564-017-0072-8. Epub 2017 Dec 18. Review. Erratum in: Nat Microbiol. 2018 Feb 13;:.

16.

CORK Study in Cystic Fibrosis: Sustained Improvements in Ultra-Low-Dose Chest CT Scores After CFTR Modulation With Ivacaftor.

Ronan NJ, Einarsson GG, Twomey M, Mooney D, Mullane D, NiChroinin M, O'Callaghan G, Shanahan F, Murphy DM, O'Connor OJ, Shortt CA, Tunney MM, Eustace JA, Maher MM, Elborn JS, Plant BJ.

Chest. 2018 Feb;153(2):395-403. doi: 10.1016/j.chest.2017.10.005. Epub 2017 Oct 14.

PMID:
29037527
17.

The oral microbiota in colorectal cancer is distinctive and predictive.

Flemer B, Warren RD, Barrett MP, Cisek K, Das A, Jeffery IB, Hurley E, O'Riordain M, Shanahan F, O'Toole PW.

Gut. 2018 Aug;67(8):1454-1463. doi: 10.1136/gutjnl-2017-314814. Epub 2017 Oct 7.

18.

Microbial regulation of microRNA expression in the amygdala and prefrontal cortex.

Hoban AE, Stilling RM, M Moloney G, Moloney RD, Shanahan F, Dinan TG, Cryan JF, Clarke G.

Microbiome. 2017 Aug 25;5(1):102. doi: 10.1186/s40168-017-0321-3.

19.

Editorial: probiotics in inflammatory bowel disease-wrong organisms, wrong disease, or flawed concepts?

Shanahan F.

Aliment Pharmacol Ther. 2017 Sep;46(6):632-633. doi: 10.1111/apt.14230. No abstract available.

PMID:
28805324
20.

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.

McDonald ER 3rd, de Weck A, Schlabach MR, Billy E, Mavrakis KJ, Hoffman GR, Belur D, Castelletti D, Frias E, Gampa K, Golji J, Kao I, Li L, Megel P, Perkins TA, Ramadan N, Ruddy DA, Silver SJ, Sovath S, Stump M, Weber O, Widmer R, Yu J, Yu K, Yue Y, Abramowski D, Ackley E, Barrett R, Berger J, Bernard JL, Billig R, Brachmann SM, Buxton F, Caothien R, Caushi JX, Chung FS, Cortés-Cros M, deBeaumont RS, Delaunay C, Desplat A, Duong W, Dwoske DA, Eldridge RS, Farsidjani A, Feng F, Feng J, Flemming D, Forrester W, Galli GG, Gao Z, Gauter F, Gibaja V, Haas K, Hattenberger M, Hood T, Hurov KE, Jagani Z, Jenal M, Johnson JA, Jones MD, Kapoor A, Korn J, Liu J, Liu Q, Liu S, Liu Y, Loo AT, Macchi KJ, Martin T, McAllister G, Meyer A, Mollé S, Pagliarini RA, Phadke T, Repko B, Schouwey T, Shanahan F, Shen Q, Stamm C, Stephan C, Stucke VM, Tiedt R, Varadarajan M, Venkatesan K, Vitari AC, Wallroth M, Weiler J, Zhang J, Mickanin C, Myer VE, Porter JA, Lai A, Bitter H, Lees E, Keen N, Kauffmann A, Stegmeier F, Hofmann F, Schmelzle T, Sellers WR.

Cell. 2017 Jul 27;170(3):577-592.e10. doi: 10.1016/j.cell.2017.07.005.

21.

A pilot study demonstrating the altered gut microbiota functionality in stable adults with Cystic Fibrosis.

Fouhy F, Ronan NJ, O'Sullivan O, McCarthy Y, Walsh AM, Murphy DM, Daly M, Flanagan ET, Fleming C, McCarthy M, Shortt C, Eustace JA, Shanahan F, Rea MC, Ross RP, Stanton C, Plant BJ.

Sci Rep. 2017 Jul 27;7(1):6685. doi: 10.1038/s41598-017-06880-y.

22.

Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes.

Moloney GM, O'Leary OF, Salvo-Romero E, Desbonnet L, Shanahan F, Dinan TG, Clarke G, Cryan JF.

Behav Brain Res. 2017 Sep 15;334:50-54. doi: 10.1016/j.bbr.2017.07.026. Epub 2017 Jul 20.

PMID:
28736331
23.

Feeding the microbiota: transducer of nutrient signals for the host.

Shanahan F, van Sinderen D, O'Toole PW, Stanton C.

Gut. 2017 Sep;66(9):1709-1717. doi: 10.1136/gutjnl-2017-313872. Epub 2017 Jun 29. Review.

PMID:
28663354
24.

Microbiota regulates visceral pain in the mouse.

Luczynski P, Tramullas M, Viola M, Shanahan F, Clarke G, O'Mahony S, Dinan TG, Cryan JF.

Elife. 2017 Jun 20;6. pii: e25887. doi: 10.7554/eLife.25887.

25.

The microbiome regulates amygdala-dependent fear recall.

Hoban AE, Stilling RM, Moloney G, Shanahan F, Dinan TG, Clarke G, Cryan JF.

Mol Psychiatry. 2018 May;23(5):1134-1144. doi: 10.1038/mp.2017.100. Epub 2017 May 16.

26.

The effect of exercise interventions on inflammatory biomarkers in healthy, physically inactive subjects: a systematic review.

Cronin O, Keohane DM, Molloy MG, Shanahan F.

QJM. 2017 Oct 1;110(10):629-637. doi: 10.1093/qjmed/hcx091. Review.

PMID:
28472518
27.

Erratum to: The altered gut microbiota in adults with cystic fibrosis.

Burke DG, Fouhy F, Harrison MJ, Rea MC, Cotter PD, O'Sullivan O, Stanton C, Hill C, Shanahan F, Plant BJ, Ross RP.

BMC Microbiol. 2017 Apr 27;17(1):102. doi: 10.1186/s12866-017-1006-6. No abstract available.

28.

The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level.

Barton W, Penney NC, Cronin O, Garcia-Perez I, Molloy MG, Holmes E, Shanahan F, Cotter PD, O'Sullivan O.

Gut. 2018 Apr;67(4):625-633. doi: 10.1136/gutjnl-2016-313627. Epub 2017 Mar 30.

29.

GREB1 genetic variants are associated with bone mineral density in Caucasians.

Hegarty KG, Drummond FJ, Daly M, Shanahan F, Molloy MG.

J Bone Miner Metab. 2018 Mar;36(2):189-199. doi: 10.1007/s00774-017-0823-x. Epub 2017 Mar 14.

PMID:
28293781
30.

Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E-/- mice.

Ryan PM, London LE, Bjorndahl TC, Mandal R, Murphy K, Fitzgerald GF, Shanahan F, Ross RP, Wishart DS, Caplice NM, Stanton C.

Microbiome. 2017 Mar 13;5(1):30. doi: 10.1186/s40168-017-0246-x.

31.

The altered gut microbiota in adults with cystic fibrosis.

Burke DG, Fouhy F, Harrison MJ, Rea MC, Cotter PD, O'Sullivan O, Stanton C, Hill C, Shanahan F, Plant BJ, Ross RP.

BMC Microbiol. 2017 Mar 9;17(1):58. doi: 10.1186/s12866-017-0968-8. Erratum in: BMC Microbiol. 2017 Apr 27;17 (1):102.

32.

Bifidobacterium breve with α-linolenic acid alters the composition, distribution and transcription factor activity associated with metabolism and absorption of fat.

Patterson E, Wall R, Lisai S, Ross RP, Dinan TG, Cryan JF, Fitzgerald GF, Banni S, Quigley EM, Shanahan F, Stanton C.

Sci Rep. 2017 Mar 7;7:43300. doi: 10.1038/srep43300.

33.

The influence of rosuvastatin on the gastrointestinal microbiota and host gene expression profiles.

Nolan JA, Skuse P, Govindarajan K, Patterson E, Konstantinidou N, Casey PG, MacSharry J, Shanahan F, Stanton C, Hill C, Cotter PD, Joyce SA, Gahan CGM.

Am J Physiol Gastrointest Liver Physiol. 2017 May 1;312(5):G488-G497. doi: 10.1152/ajpgi.00149.2016. Epub 2017 Feb 16.

34.

The Gut Microbiota in Inflammatory Bowel Disease.

Sheehan D, Shanahan F.

Gastroenterol Clin North Am. 2017 Mar;46(1):143-154. doi: 10.1016/j.gtc.2016.09.011. Epub 2017 Jan 4. Review.

PMID:
28164847
35.

Gut microbiota: implications for sports and exercise medicine.

Cronin O, O'Sullivan O, Barton W, Cotter PD, Molloy MG, Shanahan F.

Br J Sports Med. 2017 May;51(9):700-701. doi: 10.1136/bjsports-2016-097225. Epub 2017 Jan 11. No abstract available.

PMID:
28077354
36.

The Changing Phenotype of Inflammatory Bowel Disease.

Moran C, Sheehan D, Shanahan F.

Gastroenterol Res Pract. 2016;2016:1619053. doi: 10.1155/2016/1619053. Epub 2016 Dec 6. Review.

37.

Clostridium difficile carriage in adult cystic fibrosis (CF); implications for patients with CF and the potential for transmission of nosocomial infection.

Burke DG, Harrison MJ, Fleming C, McCarthy M, Shortt C, Sulaiman I, Murphy DM, Eustace JA, Shanahan F, Hill C, Stanton C, Rea MC, Ross RP, Plant BJ.

J Cyst Fibros. 2017 Mar;16(2):291-298. doi: 10.1016/j.jcf.2016.09.008. Epub 2016 Nov 29.

PMID:
27908697
38.

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk.

Govindarajan K, MacSharry J, Casey PG, Shanahan F, Joyce SA, Gahan CG.

PLoS One. 2016 Dec 1;11(12):e0167319. doi: 10.1371/journal.pone.0167319. eCollection 2016.

39.

Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus.

Luczynski P, Whelan SO, O'Sullivan C, Clarke G, Shanahan F, Dinan TG, Cryan JF.

Eur J Neurosci. 2016 Nov;44(9):2654-2666. doi: 10.1111/ejn.13291. Epub 2016 Jul 8.

40.

A randomised, double-blind, placebo-controlled clinical study: the effects of a synbiotic, Lepicol, in adults with chronic, functional constipation.

Cudmore S, Doolan A, Lacey S, Shanahan F.

Int J Food Sci Nutr. 2017 May;68(3):366-377. doi: 10.1080/09637486.2016.1244661. Epub 2016 Oct 24.

PMID:
27776217
41.

Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue.

Zhdanov AV, Okkelman IA, Golubeva AV, Doerr B, Hyland NP, Melgar S, Shanahan F, Cryan JF, Papkovsky DB.

Cell Mol Life Sci. 2017 Jan;74(1):141-151. doi: 10.1007/s00018-016-2323-x. Epub 2016 Aug 10.

PMID:
27510419
42.

Preparation of a standardised faecal slurry for ex-vivo microbiota studies which reduces inter-individual donor bias.

O'Donnell MM, Rea MC, O'Sullivan Ó, Flynn C, Jones B, McQuaid A, Shanahan F, Ross RP.

J Microbiol Methods. 2016 Oct;129:109-116. doi: 10.1016/j.mimet.2016.08.002. Epub 2016 Aug 4.

PMID:
27498348
43.

Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene.

Bloomfield SF, Rook GA, Scott EA, Shanahan F, Stanwell-Smith R, Turner P.

Perspect Public Health. 2016 Jul;136(4):213-24. doi: 10.1177/1757913916650225.

44.

Microbial contributions to chronic inflammation and metabolic disease.

Shanahan F, Sheehan D.

Curr Opin Clin Nutr Metab Care. 2016 Jul;19(4):257-62. doi: 10.1097/MCO.0000000000000282. Review.

PMID:
27097361
45.

Regulation of prefrontal cortex myelination by the microbiota.

Hoban AE, Stilling RM, Ryan FJ, Shanahan F, Dinan TG, Claesson MJ, Clarke G, Cryan JF.

Transl Psychiatry. 2016 Apr 5;6:e774. doi: 10.1038/tp.2016.42.

46.

Tumour-associated and non-tumour-associated microbiota in colorectal cancer.

Flemer B, Lynch DB, Brown JM, Jeffery IB, Ryan FJ, Claesson MJ, O'Riordain M, Shanahan F, O'Toole PW.

Gut. 2017 Apr;66(4):633-643. doi: 10.1136/gutjnl-2015-309595. Epub 2016 Mar 18.

47.

Exercise, fitness, and the gut.

Cronin O, Molloy MG, Shanahan F.

Curr Opin Gastroenterol. 2016 Mar;32(2):67-73. doi: 10.1097/MOG.0000000000000240. Review.

PMID:
26839963
48.

IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.

Russell SE, Horan RM, Stefanska AM, Carey A, Leon G, Aguilera M, Statovci D, Moran T, Fallon PG, Shanahan F, Brint EK, Melgar S, Hussey S, Walsh PT.

Mucosal Immunol. 2016 Sep;9(5):1193-204. doi: 10.1038/mi.2015.134. Epub 2016 Jan 27.

PMID:
26813344
49.

Pure Iterative Reconstruction Improves Image Quality in Computed Tomography of the Abdomen and Pelvis Acquired at Substantially Reduced Radiation Doses in Patients With Active Crohn Disease.

McLaughlin PD, Murphy KP, Twomey M, OʼNeill SB, Moloney F, OʼConnor OJ, OʼRegan K, McSweeney S, McGarrigle AM, Moore N, Bye J, Shanahan F, Maher MM.

J Comput Assist Tomogr. 2016 Mar-Apr;40(2):225-33. doi: 10.1097/RCT.0000000000000358.

PMID:
26760188
50.

How mothers mediate the social integration of their children conceived of forced marriage within the Lord's Resistance Army.

Shanahan F, Veale A.

Child Abuse Negl. 2016 Jan;51:72-86. doi: 10.1016/j.chiabu.2015.11.003. Epub 2015 Dec 6.

PMID:
26671833

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