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Thrombolysis in Acute Stroke Due to Thrombosed Aneurysm.

Lun RR, Cora EA, Iancu D, Graveline J, Figurado P, Shamy M.

Neurohospitalist. 2019 Oct;9(4):226-229. doi: 10.1177/1941874418825187. Epub 2019 Jan 22.


Effect of Recombinant Activated Coagulation Factor VII on Hemorrhage Expansion Among Patients With Spot Sign-Positive Acute Intracerebral Hemorrhage: The SPOTLIGHT and STOP-IT Randomized Clinical Trials.

Gladstone DJ, Aviv RI, Demchuk AM, Hill MD, Thorpe KE, Khoury JC, Sucharew HJ, Al-Ajlan F, Butcher K, Dowlatshahi D, Gubitz G, De Masi S, Hall J, Gregg D, Mamdani M, Shamy M, Swartz RH, Del Campo CM, Cucchiara B, Panagos P, Goldstein JN, Carrozzella J, Jauch EC, Broderick JP, Flaherty ML; SPOTLIGHT and STOP-IT Investigators and Coordinators.

JAMA Neurol. 2019 Aug 19. doi: 10.1001/jamaneurol.2019.2636. [Epub ahead of print]


Protocol for a systematic scoping review of reasons given to justify the performance of randomised controlled trials.

Dewar B, Fedyk M, Jurkovic L, Chevrier S, Rodriguez R, Kitto SC, Saginur R, Shamy M.

BMJ Open. 2019 Jul 26;9(7):e027575. doi: 10.1136/bmjopen-2018-027575.


Response by Dewar and Shamy to Letter Regarding Article "Deferral of Consent in Acute Stroke Trials: Lessons From the ESCAPE Trial".

Dewar B, Shamy MCF.

Stroke. 2019 Aug;50(8):e236. doi: 10.1161/STROKEAHA.119.026278. Epub 2019 Jul 5. No abstract available.


Need for Randomized Trials to Support Procedural Interventions.

Dewar B, Shamy M.

JAMA. 2019 May 21;321(19):1938. doi: 10.1001/jama.2019.2036. No abstract available.


Deferral of Consent in Acute Stroke Trials.

Shamy MCF, Dewar B, Chevrier S, Wang CQ, Page S, Goyal M, Demchuk AM, Hill MD.

Stroke. 2019 Apr;50(4):1017-1020. doi: 10.1161/STROKEAHA.118.024096.


RecoverNow: A mobile tablet-based therapy platform for early stroke rehabilitation.

Pugliese M, Ramsay T, Shamloul R, Mallet K, Zakutney L, Corbett D, Dukelow S, Stotts G, Shamy M, Wilson K, Guerinet J, Dowlatshahi D.

PLoS One. 2019 Jan 25;14(1):e0210725. doi: 10.1371/journal.pone.0210725. eCollection 2019.


How do neurologists diagnose transient ischemic attack: A systematic review.

Fitzpatrick T, Gocan S, Wang CQ, Hamel C, Bourgoin A, Dowlatshahi D, Stotts G, Shamy M.

Int J Stroke. 2019 Feb;14(2):115-124. doi: 10.1177/1747493018816430. Epub 2018 Dec 3.


Biological, Legal, and Moral Definitions of Brain Death.

Dewar B, Fedyk M, Shamy MCF.

JAMA. 2018 Oct 9;320(14):1494. doi: 10.1001/jama.2018.10980. No abstract available.


Harnessing the power of placebos in movement disorders: Insights from Parkinson's disease in clinical research and practice.

Mestre TA, Shamy M, Benedetti F, Lang AE.

Mov Disord. 2018 Aug;33(8):1195-1203. doi: 10.1002/mds.27409. Epub 2018 Aug 25. Review.


Canadian Stroke Best Practice Recommendations for Acute Stroke Management: Prehospital, Emergency Department, and Acute Inpatient Stroke Care, 6th Edition, Update 2018.

Boulanger JM, Lindsay MP, Gubitz G, Smith EE, Stotts G, Foley N, Bhogal S, Boyle K, Braun L, Goddard T, Heran M, Kanya-Forster N, Lang E, Lavoie P, McClelland M, O'Kelly C, Pageau P, Pettersen J, Purvis H, Shamy M, Tampieri D, vanAdel B, Verbeek R, Blacquiere D, Casaubon L, Ferguson D, Hegedus Y, Jacquin GJ, Kelly M, Kamal N, Linkewich B, Lum C, Mann B, Milot G, Newcommon N, Poirier P, Simpkin W, Snieder E, Trivedi A, Whelan R, Eustace M, Smitko E, Butcher K.

Int J Stroke. 2018 Dec;13(9):949-984. doi: 10.1177/1747493018786616. Epub 2018 Jul 18. Review.


RecoverNow: A patient perspective on the delivery of mobile tablet-based stroke rehabilitation in the acute care setting.

Mallet K, Shamloul R, Pugliese M, Power E, Corbett D, Hatcher S, Shamy M, Stotts G, Zakutney L, Dukelow S, Dowlatshahi D.

Int J Stroke. 2019 Feb;14(2):174-179. doi: 10.1177/1747493018790031. Epub 2018 Jul 18.


Diagnostic accuracy of whole-brain computed tomography perfusion for detection of ischemic stroke in patients with mild neurological symptoms.

Frank RA, Chakraborty S, McGrath T, Mungham A, Ross J, Dowlatshahi D, Shamy M, Stotts G.

Neuroradiol J. 2018 Oct;31(5):464-472. doi: 10.1177/1971400918770898. Epub 2018 May 3.


Reply to: Letter to the Editor by M. Olsen, M. K. Sharp, and P. M. Bossuyt.

Shamy M, Fedyk M.

J Clin Epidemiol. 2018 Jul;99:171. doi: 10.1016/j.jclinepi.2018.03.009. Epub 2018 Mar 26. No abstract available.


Sucrose diester of aryldihydronaphthalene-type lignans from Echium angustifolium Mill. and their antitumor activity.

El-Rokh AR, Negm A, El-Shamy M, El-Gindy M, Abdel-Mogib M.

Phytochemistry. 2018 May;149:155-160. doi: 10.1016/j.phytochem.2018.02.014. Epub 2018 Mar 5.


Why the ethical justification of randomized clinical trials is a scientific question.

Shamy M, Fedyk M.

J Clin Epidemiol. 2018 May;97:126-132. doi: 10.1016/j.jclinepi.2017.12.026. Epub 2018 Jan 3. No abstract available.


Many randomized clinical trials may not be justified: a cross-sectional analysis of the ethics and science of randomized clinical trials.

De Meulemeester J, Fedyk M, Jurkovic L, Reaume M, Dowlatshahi D, Stotts G, Shamy M.

J Clin Epidemiol. 2018 May;97:20-25. doi: 10.1016/j.jclinepi.2017.12.027. Epub 2018 Jan 3.


Association between Exposure to Ambient Air Particulates and Metabolic Syndrome Components in a Saudi Arabian Population.

Shamy M, Alghamdi M, Khoder MI, Mohorjy AM, Alkhatim AA, Alkhalaf AK, Brocato J, Chen LC, Thurston GD, Lim CC, Costa M.

Int J Environ Res Public Health. 2017 Dec 25;15(1). pii: E27. doi: 10.3390/ijerph15010027.


Risk Assessment and Implication of Human Exposure to Road Dust Heavy Metals in Jeddah, Saudi Arabia.

Shabbaj II, Alghamdi MA, Shamy M, Hassan SK, Alsharif MM, Khoder MI.

Int J Environ Res Public Health. 2017 Dec 26;15(1). pii: E36. doi: 10.3390/ijerph15010036.


Serpiginous cranial arterial calcification in uremia.

Shamy MC, Yogendrakumar V, Iancu D, Bourque PR.

Neurology. 2017 Oct 3;89(14):1530-1531. doi: 10.1212/WNL.0000000000004546. No abstract available.


Intra-arterial milrinone may differentiate fulminant RCVS from vasculitis.

Laneuville M, Ding J, Shamy M, Lum C, Dowlatshahi D.

Neurology. 2017 Sep 5;89(10):1093-1094. doi: 10.1212/WNL.0000000000004337. No abstract available.


Temporal variations of fine and coarse particulate matter sources in Jeddah, Saudi Arabia.

Lim CC, Thurston GD, Shamy M, Alghamdi M, Khoder M, Mohorjy AM, Alkhalaf AK, Brocato J, Chen LC, Costa M.

J Air Waste Manag Assoc. 2018 Feb;68(2):123-138. doi: 10.1080/10962247.2017.1344158. Epub 2018 Jan 16.


Translating futility.

Kyriakopoulos P, Fedyk M, Shamy M.

CMAJ. 2017 Jun 12;189(23):E805-E806. doi: 10.1503/cmaj.161354. No abstract available.


Polycyclic aromatic hydrocarbons (PAHs) in the settled dust of automobile workshops, health and carcinogenic risk evaluation.

Ali N, Ismail IMI, Khoder M, Shamy M, Alghamdi M, Al Khalaf A, Costa M.

Sci Total Environ. 2017 Dec 1;601-602:478-484. doi: 10.1016/j.scitotenv.2017.05.110. Epub 2017 May 31.


Developing transgenic wheat to encounter rusts and powdery mildew by overexpressing barley chi26 gene for fungal resistance.

Eissa HF, Hassanien SE, Ramadan AM, El-Shamy MM, Saleh OM, Shokry AM, Abdelsattar M, Morsy YB, El-Maghraby MA, Alameldin HF, Hassan SM, Osman GH, Mahfouz HT, Gad El-Karim GA, Madkour MA, Bahieldin A.

Plant Methods. 2017 May 22;13:41. doi: 10.1186/s13007-017-0191-5. eCollection 2017.


Evaluation of the Effects of Airborne Particulate Matter on Bone Marrow-Mesenchymal Stem Cells (BM-MSCs): Cellular, Molecular and Systems Biological Approaches.

Abu-Elmagd M, Alghamdi MA, Shamy M, Khoder MI, Costa M, Assidi M, Kadam R, Alsehli H, Gari M, Pushparaj PN, Kalamegam G, Al-Qahtani MH.

Int J Environ Res Public Health. 2017 Apr 20;14(4). pii: E440. doi: 10.3390/ijerph14040440.


A Novel Neuroscience Intermediate-Level Care Unit Model: Retrospective Analysis of Impact on Patient Flow and Safety.

Quimby AE, Shamy MC, Rothwell DM, Liu EY, Dowlatshahi D, Stotts G.

Neurohospitalist. 2017 Apr;7(2):83-90. doi: 10.1177/1941874416672558. Epub 2016 Oct 15.


Health risk associated with airborne particulate matter and its components in Jeddah, Saudi Arabia.

Harrison RM, Bousiotis D, Mohorjy AM, Alkhalaf AK, Shamy M, Alghamdi M, Khoder M, Costa M.

Sci Total Environ. 2017 Jul 15;590-591:531-539. doi: 10.1016/j.scitotenv.2017.02.216. Epub 2017 Mar 9.


Clinical Trials Involving Hypertension.

Shamy M, Fedyk M.

N Engl J Med. 2017 Jan 19;376(3):289-90. No abstract available.


RecoverNow: Feasibility of a Mobile Tablet-Based Rehabilitation Intervention to Treat Post-Stroke Communication Deficits in the Acute Care Setting.

Mallet KH, Shamloul RM, Corbett D, Finestone HM, Hatcher S, Lumsden J, Momoli F, Shamy MC, Stotts G, Swartz RH, Yang C, Dowlatshahi D.

PLoS One. 2016 Dec 21;11(12):e0167950. doi: 10.1371/journal.pone.0167950. eCollection 2016.


A Case Study in the History of Neurology.

Day GS, Tang-Wai DF, Shamy MC.

Neurohospitalist. 2016 Oct;6(4):181-184. Epub 2016 May 27.


Polycyclic aromatic hydrocarbons (PAHs) in indoor dust samples from Cities of Jeddah and Kuwait: Levels, sources and non-dietary human exposure.

Ali N, Ismail IMI, Khoder M, Shamy M, Alghamdi M, Costa M, Ali LN, Wang W, Eqani SAMAS.

Sci Total Environ. 2016 Dec 15;573:1607-1614. doi: 10.1016/j.scitotenv.2016.09.134. Epub 2016 Sep 24.


Virulence Analysis of Wheat Powdery Mildew (Blumeria graminis f. sp. tritici) and Effective Genes in Middle Delta, Egypt.

El-Shamy MM, Emara HM, Mohamed ME.

Plant Dis. 2016 Sep;100(9):1927-1930. doi: 10.1094/PDIS-01-16-0130-RE. Epub 2016 Jun 30.


How Patient Demographics, Imaging, and Beliefs Influence Tissue-Type Plasminogen Activator Use: A Survey of North American Neurologists.

Shamy MC, Pugliese M, Meisel K, Rodriguez R, Kim AS, Stahnisch FW, Smith EE.

Stroke. 2016 Aug;47(8):2051-7. doi: 10.1161/STROKEAHA.116.013344. Epub 2016 Jun 30.


Decision Making and the Limits of Evidence: A Case Study of Acute Stroke in Pregnancy.

Boyko M, Iancu D, Lesiuk H, Dowlatshahi D, Shamy MC.

Neurohospitalist. 2016 Apr;6(2):70-5. doi: 10.1177/1941874415594120. Epub 2015 Jul 2.


Natural course of total mismatch and predictors for tissue infarction.

Shamy MC.

Neurology. 2016 Mar 1;86(9):880. doi: 10.1212/WNL.0000000000002458. No abstract available.


In Vivo Exposures to Particulate Matter Collected from Saudi Arabia or Nickel Chloride Display Similar Dysregulation of Metabolic Syndrome Genes.

Brocato J, Hernandez M, Laulicht F, Sun H, Shamy M, Alghamdi MA, Khoder MI, Kluz T, Chen LC, Costa M.

J Toxicol Environ Health A. 2015;78(23-24):1421-36. doi: 10.1080/15287394.2015.1095689.


Association between sleeping hours and cardiometabolic risk factors for metabolic syndrome in a Saudi Arabian population.

Brocato J, Wu F, Chen Y, Shamy M, Alghamdi MA, Khoder MI, Alkhatim AA, Abdou MH, Costa M.

BMJ Open. 2015 Nov 30;5(11):e008590. doi: 10.1136/bmjopen-2015-008590.


The Canadian Management of Bovine Spongiform Encephalopathy in Historical and Scientific Perspective, 1990-2014.

Quimby AE, Shamy MC.

Can J Neurol Sci. 2015 Nov;42(6):472-81. doi: 10.1017/cjn.2015.286. Epub 2015 Sep 11. Review.


Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift.

Kamal N, Hill MD, Blacquiere DP, Boulanger JM, Boyle K, Buck B, Butcher K, Camden MC, Casaubon LK, Côté R, Demchuk AM, Dowlatshahi D, Dubuc V, Field TS, Ghrooda E, Gioia L, Gladstone DJ, Goyal M, Gubitz GJ, Harris D, Hart RG, Hunter G, Jeerakathil T, Jin A, Khan K, Lang E, Lanthier S, Lindsay MP, Mackey A, Mandzia J, Mehdiratta M, Minuk J, Oczkowski W, Odier C, Penn A, Perry J, Pettersen JA, Phillips SJ, Poppe AY, Saposnik G, Selchen D, Shamy M, Sharma M, Shoamanesh A, Shuaib A, Silver F, Stotts G, Swartz R, Tamayo A, Teitelbaum J, Verreault S, Wein T, Yip S, Coutts SB.

Stroke. 2015 Oct;46(10):2987-90. doi: 10.1161/STROKEAHA.115.010454. Epub 2015 Aug 27. No abstract available.


Should CT Angiography be a Routine Component of Acute Stroke Imaging?

Douglas V, Shamy M, Bhattacharya P.

Neurohospitalist. 2015 Jul;5(3):97-8. doi: 10.1177/1941874415588393. No abstract available.


Urinary metabolites of polycyclic aromatic hydrocarbons in Saudi Arabian schoolchildren in relation to sources of exposure.

Alghamdi MA, Alam MS, Stark C, Mohammed N, Harrison RM, Shamy M, Khoder MI, Shabbaj II, Göen T.

Environ Res. 2015 Jul;140:495-501. doi: 10.1016/j.envres.2015.04.023. Epub 2015 May 18.


Effects of airborne particulate matter on alternative pre-mRNA splicing in colon cancer cells.

Buggiano V, Petrillo E, Alló M, Lafaille C, Redal MA, Alghamdi MA, Khoder MI, Shamy M, Muñoz MJ, Kornblihtt AR.

Environ Res. 2015 Jul;140:185-90. doi: 10.1016/j.envres.2015.04.001. Epub 2015 Apr 9.


Huge amoebic liver abscess presented with massive right empyema: a case report.

El-Shamy M, Emara M, Attia A, Abd-Allah M, Said S.

Iran J Parasitol. 2014 Mar;9(1):141-4.


Can Mismatch Negativity Reduce Uncertainty in the Prediction of Awakening From Coma During Extracorporeal Membrane Oxygenation?

Rodriguez RA, Shamy M, Dowlatshahi D, Nathan HJ.

J Cardiothorac Vasc Anesth. 2015 Dec;29(6):1627-31. doi: 10.1053/j.jvca.2014.09.019. Epub 2015 Jan 17. No abstract available.


Fallibility: a new perspective on the ethics of clinical trial enrollment.

Shamy MC, Stahnisch FW, Hill MD.

Int J Stroke. 2015 Jan;10(1):2-6. doi: 10.1111/ijs.12376.


Receptor modelling study of polycyclic aromatic hydrocarbons in Jeddah, Saudi Arabia.

Alghamdi MA, Alam MS, Yin J, Stark C, Jang E, Harrison RM, Shamy M, Khoder MI, Shabbaj II.

Sci Total Environ. 2015 Feb 15;506-507:401-8. doi: 10.1016/j.scitotenv.2014.10.056. Epub 2014 Nov 25.


Polycyclic aromatic hydrocarbons, brachial artery distensibility and blood pressure among children residing near an oil refinery.

Trasande L, Urbina EM, Khoder M, Alghamdi M, Shabaj I, Alam MS, Harrison RM, Shamy M.

Environ Res. 2015 Jan;136:133-40. doi: 10.1016/j.envres.2014.08.038. Epub 2014 Nov 20.


Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression.

Brocato J, Fang L, Chervona Y, Chen D, Kiok K, Sun H, Tseng HC, Xu D, Shamy M, Jin C, Costa M.

J Biol Chem. 2014 Nov 14;289(46):31751-64. doi: 10.1074/jbc.M114.591883. Epub 2014 Sep 28.


Particulate matter from Saudi Arabia induces genes involved in inflammation, metabolic syndrome and atherosclerosis.

Brocato J, Sun H, Shamy M, Kluz T, Alghamdi MA, Khoder MI, Chen LC, Costa M.

J Toxicol Environ Health A. 2014;77(13):751-66. doi: 10.1080/15287394.2014.892446.

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