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Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes.

Shakya S, Sharma P, Bhatt AM, Jani RA, Delevoye C, Gangi Setty SR.

EMBO Rep. 2018 Nov 7. pii: e45918. doi: 10.15252/embr.201845918. [Epub ahead of print]


Comparison of critically ill patients from three freestanding ED's compared to a tertiary care hospital based ED.

Simon EL, Shakya S, Liu L, Griffin G, Smalley CM, Podolsky S, Engineer R.

Am J Emerg Med. 2018 Oct 11. pii: S0735-6757(18)30820-9. doi: 10.1016/j.ajem.2018.10.006. [Epub ahead of print]


Effect of geraniol against arecoline induced toxicity in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9.

Shakya B, Shakya S, Siddique YH.

Toxicol Mech Methods. 2018 Oct 15:1-54. doi: 10.1080/15376516.2018.1534299. [Epub ahead of print]


Reach and Adoption of a Randomized Weight Loss Maintenance Trial in Rural African Americans of Faith: The WORD (Wholeness, Oneness, Righteousness, Deliverance).

Yeary KHK, Moore PC, Gauss CH, Cornell C, Prewitt TE, Shakya S, Turner J, Scarbrough C, Porter G, Estabrooks PA.

Am J Health Promot. 2018 Oct 11:890117118805065. doi: 10.1177/0890117118805065. [Epub ahead of print]


Prevalence of Sexually Transmitted Infections among Married Women in Rural Nepal.

Shakya S, Thingulstad S, Syversen U, Nordbø SA, Madhup S, Vaidya K, Karmacharya BM, Åsvold BO, Afset JE.

Infect Dis Obstet Gynecol. 2018 Aug 26;2018:4980396. doi: 10.1155/2018/4980396. eCollection 2018.


Gender, medication use and other factors associated with esophageal motility disorders in non-obstructive dysphagia.

Kamal A, Shakya S, Lopez R, Thota PN.

Gastroenterol Rep (Oxf). 2018 Aug;6(3):177-183. doi: 10.1093/gastro/goy018. Epub 2018 Jun 2.


Identification of beagle food taking patterns and protocol for food effects evaluation on bioavailability.

Zhang G, Wang C, Wu L, Xu J, Hu X, Shakya S, He Y, Ren X, Chen W, Zhang J.

Sci Rep. 2018 Aug 24;8(1):12765. doi: 10.1038/s41598-018-30937-1.


Perceived social support, coping, and stigma on the quality of life of people living with HIV in Nepal: a moderated mediation analysis.

Shrestha S, Shibanuma A, Poudel KC, Nanishi K, Koyama Abe M, Shakya SK, Jimba M.

AIDS Care. 2018 Jul 11:1-8. doi: 10.1080/09540121.2018.1497136. [Epub ahead of print]


Metabolic syndrome and biochemical changes among non-alcoholic fatty liver disease patients attending a tertiary care hospital of Nepal.

Pardhe BD, Shakya S, Bhetwal A, Mathias J, Khanal PR, Pandit R, Shakya J, Joshi HO, Marahatta SB.

BMC Gastroenterol. 2018 Jul 6;18(1):109. doi: 10.1186/s12876-018-0843-6.


Correlation of proliferative index with various clinicopathologic prognostic parameters in primary breast carcinoma: A study from North India.

Marwah N, Batra A, Marwah S, Gupta V, Shakya S, Sen R.

J Cancer Res Ther. 2018 Apr-Jun;14(3):537-542. doi: 10.4103/0973-1482.167614.


Ugly bugs in healthy guts! Carriage of multidrug-resistant and ESBL-producing commensal Enterobacteriaceae in the intestine of healthy Nepalese adults.

Maharjan A, Bhetwal A, Shakya S, Satyal D, Shah S, Joshi G, Khanal PR, Parajuli NP.

Infect Drug Resist. 2018 Apr 26;11:547-554. doi: 10.2147/IDR.S156593. eCollection 2018.


Relapsing Malaria: A Case Report of Primaquine Resistance.

Dijanic C, Nickerson J, Shakya S, Dijanic A, Fabbri M.

Case Rep Infect Dis. 2018 Mar 11;2018:9720823. doi: 10.1155/2018/9720823. eCollection 2018.


Molecular Mechanism of Loading Sulfur Hexafluoride in γ-Cyclodextrin Metal-Organic Framework.

Han L, Guo T, Guo Z, Wang C, Zhang W, Shakya S, Ding H, Li H, Xu X, Ren Y, Zhang J.

J Phys Chem B. 2018 May 24;122(20):5225-5233. doi: 10.1021/acs.jpcb.8b01420. Epub 2018 May 11.


Biofunctionalization of β-cyclodextrin nanosponges using cholesterol.

Singh P, Ren X, Guo T, Wu L, Shakya S, He Y, Wang C, Maharjan A, Singh V, Zhang J.

Carbohydr Polym. 2018 Jun 15;190:23-30. doi: 10.1016/j.carbpol.2018.02.044. Epub 2018 Feb 21.


Influence of Nutritional Status on the Absorption of Polyphyllin I, an Anticancer Candidate from Paris polyphylla in Rats.

Yu FL, Gong WL, Xu FJ, Wu JW, Shakya S, Zhu H.

Eur J Drug Metab Pharmacokinet. 2018 Oct;43(5):587-597. doi: 10.1007/s13318-018-0473-y.


Isolation of Potential Phages against Multidrug-Resistant Bacterial Isolates: Promising Agents in the Rivers of Kathmandu, Nepal.

Bhetwal A, Maharjan A, Shakya S, Satyal D, Ghimire S, Khanal PR, Parajuli NP.

Biomed Res Int. 2017;2017:3723254. doi: 10.1155/2017/3723254. Epub 2017 Nov 22.


Variation in hospital admission rates between a tertiary care and two freestanding emergency departments.

Simon EL, Dark C, Kovacs M, Shakya S, Meek CA.

Am J Emerg Med. 2018 Jun;36(6):967-971. doi: 10.1016/j.ajem.2017.10.066. Epub 2017 Oct 29.


Effect of age and estrogen on biochemical markers of bone turnover in postmenopausal women: a population-based study from Nepal.

Pardhe BD, Pathak S, Bhetwal A, Ghimire S, Shakya S, Khanal PR, Marahatta SB.

Int J Womens Health. 2017 Oct 25;9:781-788. doi: 10.2147/IJWH.S145191. eCollection 2017.


Identification and treatment of Nepal 2015 earthquake survivors with posttraumatic stress disorder by nonspecialist volunteers: An exploratory cross-sectional study.

Jha A, Shakya S, Zang Y, Pathak N, Pradhan PK, Bhatta KR, Sthapit S, Niraula S, Nehete R.

Indian J Psychiatry. 2017 Jul-Sep;59(3):320-327. doi: 10.4103/psychiatry.IndianJPsychiatry_236_16.


Renaissance of Conventional First-Line Antibiotics in Salmonella enterica Clinical Isolates: Assessment of MICs for Therapeutic Antimicrobials in Enteric Fever Cases from Nepal.

Khanal PR, Satyal D, Bhetwal A, Maharjan A, Shakya S, Tandukar S, Parajuli NP.

Biomed Res Int. 2017;2017:2868143. doi: 10.1155/2017/2868143. Epub 2017 Sep 5.


Updated estimation of the impact of a Japanese encephalitis immunization program with live, attenuated SA 14-14-2 vaccine in Nepal.

Upreti SR, Lindsey NP, Bohara R, Choudhary GR, Shakya S, Gautam M, Giri JN, Fischer M, Hills SL.

PLoS Negl Trop Dis. 2017 Sep 21;11(9):e0005866. doi: 10.1371/journal.pntd.0005866. eCollection 2017 Sep.


Tapping the woodpecker tree for evolutionary insight.

Shakya SB, Fuchs J, Pons JM, Sheldon FH.

Mol Phylogenet Evol. 2017 Nov;116:182-191. doi: 10.1016/j.ympev.2017.09.005. Epub 2017 Sep 7.


C-reactive Protein in Periodontitis and its Comparison with Body Mass Index and Smoking Behaviour.

Gupta S, Pradhan S, Kc S, Shakya S, Giri M.

JNMA J Nepal Med Assoc. 2017 Apr-Jun;56(206):226-233.


Single-step blood direct PCR: A robust and rapid method to diagnose triplet repeat disorders.

Singh I, Swarup V, Shakya S, Goyal V, Faruq M, Srivastava AK.

J Neurol Sci. 2017 Aug 15;379:49-54. doi: 10.1016/j.jns.2017.05.042. Epub 2017 May 22.


Elevated Cardiovascular Risks among Postmenopausal Women: A Community Based Case Control Study from Nepal.

Pardhe BD, Ghimire S, Shakya J, Pathak S, Shakya S, Bhetwal A, Khanal PR, Parajuli NP.

Biochem Res Int. 2017;2017:3824903. doi: 10.1155/2017/3824903. Epub 2017 May 2.


In-hospital complications after implantation of cardiac implantable electronic devices: Analysis of a national inpatient database in Japan.

Shakya S, Matsui H, Fushimi K, Yasunaga H.

J Cardiol. 2017 Nov;70(5):405-410. doi: 10.1016/j.jjcc.2017.02.013. Epub 2017 Apr 20.


Characterization of Salmonella Gallinarum from an outbreak in Raigarh, Chhattisgarh.

Sannat C, Patyal A, Rawat N, Ghosh RC, Jolhe DK, Shende RK, Hirpurkar SD, Shakya S.

Vet World. 2017 Feb;10(2):144-148. doi: 10.14202/vetworld.2017.144-148. Epub 2017 Feb 5.


Shigellosis Caused by CTX-M Type ESBL Producing Shigella flexneri in Two Siblings of Rural Nepal: First Case Report from the Country.

Parajuli NP, Joshi G, Pardhe BD, Shakya J, Bhetwal A, Shakya S, Pandit R, Shrestha SS, Khanal PR.

Case Rep Infect Dis. 2017;2017:1862320. doi: 10.1155/2017/1862320. Epub 2017 Feb 21.


Transforming growth factor-β1 (C509T, G800A, and T869C) gene polymorphisms and risk of ischemic stroke in North Indian population: A hospital-based case-control study.

Kumar P, Misra S, Kumar A, Faruq M, Shakya S, Vardhan G, Vivekanandhan S, Srivastava AK, Prasad K.

Ann Indian Acad Neurol. 2017 Jan-Mar;20(1):5-12. doi: 10.4103/0972-2327.199910.


Safe and pragmatic use of sodium-glucose co-transporter 2 inhibitors in type 2 diabetes mellitus: South Asian Federation of Endocrine Societies consensus statement.

Kalra S, Ghosh S, Aamir AH, Ahmed MT, Amin MF, Bajaj S, Baruah MP, Bulugahapitiya U, Das AK, Giri M, Gunatilake S, Mahar SA, Pathan MF, Qureshi NK, Raza SA, Sahay R, Shakya S, Shreshta D, Somasundaram N, Sumanatilleke M, Unnikrishnan AG, Wijesinghe AM.

Indian J Endocrinol Metab. 2017 Jan-Feb;21(1):210-230. doi: 10.4103/2230-8210.196029. Review.


"Addition" and "Subtraction": Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors.

Chen X, Giraldes J, Sprague ER, Shakya S, Chen Z, Wang Y, Joud C, Mathieu S, Chen CH, Straub C, Duca J, Hurov K, Yuan Y, Shao W, Touré BB.

J Med Chem. 2017 Mar 9;60(5):2155-2161. doi: 10.1021/acs.jmedchem.7b00033. Epub 2017 Feb 24.


Multiple recurrences of esophageal adenocarcinoma after esophagectomy.

Benjamin T, Shakya S, Thota PN.

Transl Gastroenterol Hepatol. 2016 Oct 26;1:79. doi: 10.21037/tgh.2016.09.09. eCollection 2016. No abstract available.


Discovery of 2-(((1r,4r)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.

Tran TA, Kramer B, Shin YJ, Vallar P, Boatman PD, Zou N, Sage CR, Gharbaoui T, Krishnan A, Pal B, Shakya SR, Garrido Montalban A, Adams JW, Ramirez J, Behan DP, Shifrina A, Blackburn A, Leakakos T, Shi Y, Morgan M, Sadeque A, Chen W, Unett DJ, Gaidarov I, Chen X, Chang S, Shu HH, Tung SF, Semple G.

J Med Chem. 2017 Feb 9;60(3):913-927. doi: 10.1021/acs.jmedchem.6b00871. Epub 2017 Jan 19.


Current Development of Anti-Cancer Drug S-1.

Chhetri P, Giri A, Shakya S, Shakya S, Sapkota B, Pramod KC.

J Clin Diagn Res. 2016 Nov;10(11):XE01-XE05. doi: 10.7860/JCDR/2016/19345.8776. Epub 2016 Nov 1. Review.


Bacteremia caused by a rare pathogen - Chromobacterium violaceum: a case report from Nepal.

Parajuli NP, Bhetwal A, Ghimire S, Maharjan A, Shakya S, Satyal D, Pandit R, Khanal PR.

Int J Gen Med. 2016 Dec 5;9:441-446. eCollection 2016.


Rebamipide to Manage Stomatopyrosis in Oral Submucous Fibrosis.

Baptist J, Shakya S, Ongole R.

J Contemp Dent Pract. 2016 Dec 1;17(12):1009-1012.


Cognitive Dysfunctions in Patients with Alcohol Dependence Syndrome in a Tertiary Hospital in Kathmandu.

Adhikari S, Rana M, Shakya S, Ojha SP.

JNMA J Nepal Med Assoc. 2016 Jan-Mar;54(201):17-23.


Iron related hemochromatosis (HFE) gene mutations in Friedreich Ataxia patients.

Singh I, Shakya S, Singh RK, Ahmad I, Goyal V, Shukla G, Srivastava MV, Faruq M, Srivastava AK.

Parkinsonism Relat Disord. 2017 Jan;34:71-72. doi: 10.1016/j.parkreldis.2016.10.015. Epub 2016 Oct 19. No abstract available.


Probiotics Prevent Candida Colonization and Invasive Fungal Sepsis in Preterm Neonates: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Hu HJ, Zhang GQ, Zhang Q, Shakya S, Li ZY.

Pediatr Neonatol. 2017 Apr;58(2):103-110. doi: 10.1016/j.pedneo.2016.06.001. Epub 2016 Sep 14. Review.


Prevalence of human papillomavirus infection among women in rural Nepal.

Shakya S, Syversen U, Åsvold BO, Bofin AM, Aune G, Nordbø SA, Vaidya KM, Karmacharya BM, Afset JE, Tingulstad S.

Acta Obstet Gynecol Scand. 2017 Jan;96(1):29-38. doi: 10.1111/aogs.13036. Epub 2016 Nov 23.


Real-Time Monitoring of Vaccination Campaign Performance Using Mobile Phones - Nepal, 2016.

Oh DH, Dabbagh A, Goodson JL, Strebel PM, Thapa S, Giri JN, Shakya SR, Khanal S.

MMWR Morb Mortal Wkly Rep. 2016 Oct 7;65(39):1072-1076. doi: 10.15585/mmwr.mm6539a5.


Coconut oil induced production of a surfactant-compatible lipase from Aspergillus tamarii under submerged fermentation.

Das A, Bhattacharya S, Shivakumar S, Shakya S, Sogane SS.

J Basic Microbiol. 2017 Feb;57(2):114-120. doi: 10.1002/jobm.201600478. Epub 2016 Oct 6.


Feasibility of volumetric laser endomicroscopy in Barrett's esophagus with dysplasia and in post-ablation surveillance.

Benjamin T, Shakya S, Thota PN.

J Gastrointestin Liver Dis. 2016 Sep;25(3):407-8. doi: 10.15403/jgld.2014.1121.253.brt. No abstract available.


Metabolic profile and pharmacokinetics of polyphyllin I, an anticancer candidate, in rats by UPLC-QTOF-MS/MS and LC-TQ-MS/MS.

Liu YC, Zhu H, Shakya S, Wu JW.

Biomed Chromatogr. 2017 Mar;31(3). doi: 10.1002/bmc.3817. Epub 2016 Sep 15.


Problems Faced by Antiretroviral (ARV) Drug Users in Kathmandu.

Karki J, Shakya S.

J Nepal Health Res Counc. 2016 Jan;14(32):27-32.


Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.

Chen YN, LaMarche MJ, Chan HM, Fekkes P, Garcia-Fortanet J, Acker MG, Antonakos B, Chen CH, Chen Z, Cooke VG, Dobson JR, Deng Z, Fei F, Firestone B, Fodor M, Fridrich C, Gao H, Grunenfelder D, Hao HX, Jacob J, Ho S, Hsiao K, Kang ZB, Karki R, Kato M, Larrow J, La Bonte LR, Lenoir F, Liu G, Liu S, Majumdar D, Meyer MJ, Palermo M, Perez L, Pu M, Price E, Quinn C, Shakya S, Shultz MD, Slisz J, Venkatesan K, Wang P, Warmuth M, Williams S, Yang G, Yuan J, Zhang JH, Zhu P, Ramsey T, Keen NJ, Sellers WR, Stams T, Fortin PD.

Nature. 2016 Jul 7;535(7610):148-52. Epub 2016 Jun 29.


Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight.

Touré BB, Giraldes J, Smith T, Sprague ER, Wang Y, Mathieu S, Chen Z, Mishina Y, Feng Y, Yan-Neale Y, Shakya S, Chen D, Meyer M, Puleo D, Brazell JT, Straub C, Sage D, Wright K, Yuan Y, Chen X, Duca J, Kim S, Tian L, Martin E, Hurov K, Shao W.

J Med Chem. 2016 May 26;59(10):4711-23. doi: 10.1021/acs.jmedchem.6b00052. Epub 2016 May 17.


Isolation and molecular characterization of Salmonella spp. from chevon and chicken meat collected from different districts of Chhattisgarh, India.

Naik VK, Shakya S, Patyal A, Gade NE, Bhoomika.

Vet World. 2015 Jun;8(6):702-6. doi: 10.14202/vetworld.2015.702-706. Epub 2015 Jun 6.

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