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Items: 1 to 50 of 64

1.

Changing epidemiology and antimicrobial resistance in Vibrio cholerae: AMR surveillance findings (2006-2016) from Nepal.

Rijal N, Acharya J, Adhikari S, Upadhaya BP, Shakya G, Kansakar P, Rajbhandari P.

BMC Infect Dis. 2019 Sep 11;19(1):801. doi: 10.1186/s12879-019-4432-2.

2.

Integrating postpartum contraceptive counseling and IUD insertion services into maternity care in Nepal: results from stepped-wedge randomized controlled trial.

Pradhan E, Canning D, Shah IH, Puri M, Pearson E, Thapa K, Bajracharya L, Maharjan M, Maharjan DC, Bajracharya L, Shakya G, Chaudhary P.

Reprod Health. 2019 May 29;16(1):69. doi: 10.1186/s12978-019-0738-1.

3.

Low population Japanese encephalitis virus (JEV) seroprevalence in Udayapur district, Nepal, three years after a JE vaccination programme: A case for further catch up campaigns?

Turtle L, Brindle HE, Schluter WW, Faragher B, Rayamajhi A, Bohara R, Gurung S, Shakya G, Yoksan S, Dixit S, Rajbhandari R, Paudel B, Adhikari S, Solomon T, Griffiths MJ.

PLoS Negl Trop Dis. 2019 Apr 15;13(4):e0007269. doi: 10.1371/journal.pntd.0007269. eCollection 2019 Apr.

4.

Feasibility of a Comprehensive Targeted Cholera Intervention in The Kathmandu Valley, Nepal.

Roskosky M, Acharya B, Shakya G, Karki K, Sekine K, Bajracharya D, von Seidlein L, Devaux I, Lopez AL, Deen J, Sack DA.

Am J Trop Med Hyg. 2019 May;100(5):1088-1097. doi: 10.4269/ajtmh.18-0863.

5.

Biological active matter aggregates: Inspiration for smart colloidal materials.

Vernerey FJ, Benet E, Blue L, Fajrial AK, Lalitha Sridhar S, Lum JS, Shakya G, Song KH, Thomas AN, Borden MA.

Adv Colloid Interface Sci. 2019 Jan;263:38-51. doi: 10.1016/j.cis.2018.11.006. Epub 2018 Nov 22. Review.

PMID:
30504078
6.

Outbreak Investigation Following the 2015 Earthquake Disaster in Nepal.

Shakya G, Marasini B, Karki KB, Upadhaya BP, Acharya J, Adhikari S, Manjhi R, Maharjan L, Shrestha L, Ranabhat K, Marahatta SB, Shrestha B, Dhimal M.

J Nepal Health Res Counc. 2018 Mar 13;16(1):61-65.

PMID:
29717292
7.

Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC.

Jackson DR, Shakya G, Patel AB, Mohammed LY, Vasilakis K, Wattana-Amorn P, Valentic TR, Milligan JC, Crump MP, Crosby J, Tsai SC.

ACS Chem Biol. 2018 Jan 19;13(1):141-151. doi: 10.1021/acschembio.7b00551. Epub 2017 Dec 11.

PMID:
29161022
8.

Inhibition of metastasis and angiogenesis in Hep-2 cells by wheatgrass extract - an in vitro and in silico approach.

Shakya G, Balasubramanian S, Hoda M, Rajagopalan R.

Toxicol Mech Methods. 2018 Mar;28(3):205-218. doi: 10.1080/15376516.2017.1388460. Epub 2017 Nov 21.

PMID:
29160133
9.

Dengue Virus Serotypes 1 and 2 Responsible for Major Dengue Outbreaks in Nepal: Clinical, Laboratory, and Epidemiological Features.

Dumre SP, Bhandari R, Shakya G, Shrestha SK, Cherif MS, Ghimire P, Klungthong C, Yoon IK, Hirayama K, Na-Bangchang K, Fernandez S.

Am J Trop Med Hyg. 2017 Oct;97(4):1062-1069. doi: 10.4269/ajtmh.17-0221.

10.

Strengthening laboratory surveillance of antimicrobial resistance in South East Asia.

Shah AS, Karunaratne K, Shakya G, Barreto I, Khare S, Paveenkittiporn W, Wangchuk S, Tin HH, Muhsin MA, Aung L, Bhatia R, Srivastava R, Maryandi DA.

BMJ. 2017 Sep 5;358:j3474. doi: 10.1136/bmj.j3474. No abstract available.

11.

Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.

Nakamura K, Shirakura M, Fujisaki S, Kishida N, Burke DF, Smith DJ, Kuwahara T, Takashita E, Takayama I, Nakauchi M, Chadha M, Potdar V, Bhushan A, Upadhyay BP, Shakya G, Odagiri T, Kageyama T, Watanabe S.

Influenza Other Respir Viruses. 2017 Sep;11(5):399-403. doi: 10.1111/irv.12469. Epub 2017 Aug 9.

12.

Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases.

Barajas JF, Shakya G, Moreno G, Rivera H Jr, Jackson DR, Topper CL, Vagstad AL, La Clair JJ, Townsend CA, Burkart MD, Tsai SC.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4142-E4148. doi: 10.1073/pnas.1609001114. Epub 2017 May 8.

13.

Scrub Typhus: An Emerging Neglected Tropical Disease in Nepal.

Upadhyaya BP, Shakya G, Adhikari S, Rijal N, Acharya J, Maharjan L, Marasini BR.

J Nepal Health Res Counc. 2016 May;14(33):122-127.

PMID:
27885295
14.

Shigellosis in Nepal: 13 years review of nationwide surveillance.

Shakya G, Acharya J, Adhikari S, Rijal N.

J Health Popul Nutr. 2016 Nov 4;35(1):36.

15.

Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain.

Barajas JF, Finzel K, Valentic TR, Shakya G, Gamarra N, Martinez D, Meier JL, Vagstad AL, Newman AG, Townsend CA, Burkart MD, Tsai SC.

Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13005-13009. doi: 10.1002/anie.201605401.

16.

Evaluation of SD Bioline HIV/syphilis Duo rapid test kits in Nepal.

Shakya G, Singh DR, Ojha HC, Ojha CR, Mishra SK, Malla K, Chaudhary P, Regmi K.

BMC Infect Dis. 2016 Aug 26;16(1):450. doi: 10.1186/s12879-016-1694-9.

17.

Virological and Immunological Status of the People Living with HIV/AIDS Undergoing ART Treatment in Nepal.

Ojha CR, Shakya G, Dumre SP.

Biomed Res Int. 2016;2016:6817325. doi: 10.1155/2016/6817325. Epub 2016 Jul 28.

18.

Anti-proliferative and apoptosis-triggering potential of disulfiram and disulfiram-loaded polysorbate 80-stabilized PLGA nanoparticles on hepatocellular carcinoma Hep3B cell line.

Hoda M, Pajaniradje S, Shakya G, Mohankumar K, Rajagopalan R.

Nanomedicine. 2016 Aug;12(6):1641-50. doi: 10.1016/j.nano.2016.02.013. Epub 2016 Mar 22.

PMID:
27013133
19.

Outbreak Investigation of Influenza in Pajaru VDC of Jajarkot District of Nepal.

Upadhyay SK, Singh Pradhan PM, Mahato RK, Marasini B, Upadhyaya B, Shakya G, Baral G, Baral KP.

J Nepal Health Res Counc. 2016 Sep;14(34):186-191.

PMID:
28327684
20.

Lower respiratory tract infections among HIV positive and control group in Nepal.

Ojha CR, Rijal N, Khagendra KC, Palpasa K, Kansakar P, Gupta BP, Shakya G.

Virusdisease. 2015 Jun;26(1-2):77-81. doi: 10.1007/s13337-015-0254-z. Epub 2015 Jun 23.

21.
22.

Influence of stabilizers on the production of disulfiram-loaded poly(lactic-co-glycolic acid) nanoparticles and their anticancer potential.

Hoda M, Sufi SA, Shakya G, Kumar KM, Rajagopalan R.

Ther Deliv. 2015 Jan;6(1):17-25. doi: 10.4155/tde.14.99. Erratum in: Ther Deliv. 2017 Dec;8(12):1109.

PMID:
25565438
23.

In vitro Temocillin efficacy against extended spectrum β-lactamase producing multidrug resistant gram negative bacterial isolates from Nepal.

Kandel BP, Bhatta DR, Shakya G, Upadhayay BP, Dumre SP, Poudyal S, Adhikari N, Acharya D.

Nepal Med Coll J. 2014 Dec;16(2-4):144-7.

PMID:
26930733
24.

Modeling linear and cyclic PKS intermediates through atom replacement.

Shakya G, Rivera H Jr, Lee DJ, Jaremko MJ, La Clair JJ, Fox DT, Haushalter RW, Schaub AJ, Bruegger J, Barajas JF, White AR, Kaur P, Gwozdziowski ER, Wong F, Tsai SC, Burkart MD.

J Am Chem Soc. 2014 Dec 3;136(48):16792-9. doi: 10.1021/ja5064857. Epub 2014 Nov 19.

25.

Genomic epidemiology of the Haitian cholera outbreak: a single introduction followed by rapid, extensive, and continued spread characterized the onset of the epidemic.

Eppinger M, Pearson T, Koenig SS, Pearson O, Hicks N, Agrawal S, Sanjar F, Galens K, Daugherty S, Crabtree J, Hendriksen RS, Price LB, Upadhyay BP, Shakya G, Fraser CM, Ravel J, Keim PS.

MBio. 2014 Nov 4;5(6):e01721. doi: 10.1128/mBio.01721-14.

26.

Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass.

Durairaj V, Hoda M, Shakya G, Babu SP, Rajagopalan R.

Asian Pac J Trop Med. 2014 Sep;7S1:S398-404. doi: 10.1016/S1995-7645(14)60265-0.

27.

Hypoglycaemic role of wheatgrass and its effect on carbohydrate metabolic enzymes in type II diabetic rats.

Shakya G, Randhi PK, Pajaniradje S, Mohankumar K, Rajagopalan R.

Toxicol Ind Health. 2016 Jun;32(6):1026-32. doi: 10.1177/0748233714545202. Epub 2014 Aug 12.

PMID:
25116122
28.

Prevalence of chronic hepatitis B virus infection before and after implementation of a hepatitis B vaccination program among children in Nepal.

Upreti SR, Gurung S, Patel M, Dixit SM, Krause LK, Shakya G, Wannemuehler K, Rajbhandari R, Bohara R, Schluter WW.

Vaccine. 2014 Jul 23;32(34):4304-9. doi: 10.1016/j.vaccine.2014.06.027. Epub 2014 Jun 18.

29.

Effect of wheatgrass on membrane fatty acid composition during hepatotoxicity induced by alcohol and heated PUFA.

Durairaj V, Shakya G, Pajaniradje S, Rajagopalan R.

J Membr Biol. 2014 Jun;247(6):515-21. doi: 10.1007/s00232-014-9661-0. Epub 2014 Apr 6.

PMID:
24706101
30.

Hepatoprotective Role of Wheatgrass on Alcohol and ΔPUFA-Induced Oxidative Stress in Rats.

Durairaj V, Shakya G, Rajagopalan R.

J Diet Suppl. 2015 Jun;12(2):126-37. doi: 10.3109/19390211.2014.902002. Epub 2014 Apr 3.

PMID:
24697162
31.

The challenges and successes of implementing a sustainable antimicrobial resistance surveillance programme in Nepal.

Malla S, Dumre SP, Shakya G, Kansakar P, Rai B, Hossain A, Nair GB, Albert MJ, Sack D, Baker S, Rahman M; Antimicrobial Resistance Surveillance Programme team, Nepal.

BMC Public Health. 2014 Mar 21;14:269. doi: 10.1186/1471-2458-14-269.

32.

Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.

Bruegger J, Haushalter RW, Vagstad AL, Shakya G, Mih N, Townsend CA, Burkart MD, Tsai SC.

Chem Biol. 2013 Sep 19;20(9):1135-46. doi: 10.1016/j.chembiol.2013.07.012. Epub 2013 Aug 29. Erratum in: Chem Biol. 2014 Jul 17;21(7):913. Haushalter, Bob [corrected to Haushalter, Robert W]; Vagstad, Anna [corrected to Vagstad, Anna L].

33.

Hepatoprotective role of kaempferol during alcohol- and ΔPUFA-induced oxidative stress.

Shakya G, Manjini S, Hoda M, Rajagopalan R.

J Basic Clin Physiol Pharmacol. 2014 Feb;25(1):73-9. doi: 10.1515/jbcpp-2013-0051.

PMID:
23893680
34.

Pandemic (H1N1) 2009 cases in Nepal.

Kandel N, Shrestha JM, Upadhyay B, Shrestha AK, Shakya G.

JNMA J Nepal Med Assoc. 2012 Oct-Dec;52(188):201-4.

PMID:
23591254
35.

Dengue virus and Japanese encephalitis virus epidemiological shifts in Nepal: a case of opposing trends.

Dumre SP, Shakya G, Na-Bangchang K, Eursitthichai V, Rudi Grams H, Upreti SR, Ghimire P, KC K, Nisalak A, Gibbons RV, Fernandez S.

Am J Trop Med Hyg. 2013 Apr;88(4):677-80. doi: 10.4269/ajtmh.12-0436. Epub 2013 Feb 18.

36.

Estimation of the impact of a Japanese encephalitis immunization program with live, attenuated SA 14-14-2 vaccine in Nepal.

Upreti SR, Janusz KB, Schluter WW, Bichha RP, Shakya G, Biggerstaff BJ, Shrestha MM, Sedai TR, Fischer M, Gibbons RV, Shrestha SK, Hills SL.

Am J Trop Med Hyg. 2013 Mar;88(3):464-8. doi: 10.4269/ajtmh.12-0196. Epub 2013 Jan 28.

37.

Values of lymphocyte subsets in Nepalese healthy adult population.

Shakya G, Dumre SP, Malla S, Sharma M, Kc KP, Chhetri DB, Amatya R, Paudyal P.

JNMA J Nepal Med Assoc. 2012 Jan-Mar;52(185):6-13.

PMID:
23279766
38.

Transthoracic echocardiography may be useful for preoperative cardiac evaluation of gynaecological patients undergoing routine surgery.

Shrestha B, Pradhan P, Shakya GR, Giri A, Regmi R, Dhungel S.

Nepal Med Coll J. 2012 Dec;14(4):287-93.

PMID:
24579536
39.

Diagnostic dilemma of the single screening test used in the diagnosis of syphilis in Nepal.

Dumre SP, Shakya G, Acharya D, Malla S, Adhikari N.

Nepal Med Coll J. 2011 Dec;13(4):238-40.

PMID:
23016470
40.

Comparative study of sensitivity of rapid diagnostic (hexagon) test with calculated malarial parasitic density in peripheral blood.

Shakya G, Gupta R, Pant SD, Poudel P, Upadhaya B, Sapkota A, Kc K, Ojha CR.

J Nepal Health Res Counc. 2012 Jan;10(1):16-9.

PMID:
22929630
41.

Phenotypic and genetic characterization of Vibrio cholerae O1 clinical isolates collected through national antimicrobial resistance surveillance network in Nepal.

Shakya G, Kim DW, Clemens JD, Malla S, Upadhyaya BP, Dumre SP, Shrestha SD, Adhikari S, Sharma S, Rijal N, Shrestha SK, Mason C, Kansakar P.

World J Microbiol Biotechnol. 2012 Aug;28(8):2671-8. doi: 10.1007/s11274-012-1077-3. Epub 2012 May 23.

PMID:
22806193
42.

Reply to "South Asia instead of Nepal may be the origin of the Haitian cholera outbreak strain".

Keim PS, Aarestrup FM, Shakya G, Price LB, Hendriksen RS, Engelthaler DM, Pearson T.

MBio. 2011 Nov 1;2(6):e00245-11. doi: 10.1128/mBio.00245-11. Print 2011. No abstract available.

43.

Extended spectrum â-lactamase producing multidrug resistant clinical bacterial isolates at National Public Health Laboratory, Nepal.

Poudyal S, Bhatta DR, Shakya G, Upadhyaya B, Dumre SP, Buda G, Kandel BP.

Nepal Med Coll J. 2011 Mar;13(1):34-8.

PMID:
21991699
44.

Reducing maternal mortality in Nepal.

Bhandari A, Gordon M, Shakya G.

BJOG. 2011 Sep;118 Suppl 2:26-30. doi: 10.1111/j.1471-0528.2011.03109.x. No abstract available.

45.

Population genetics of Vibrio cholerae from Nepal in 2010: evidence on the origin of the Haitian outbreak.

Hendriksen RS, Price LB, Schupp JM, Gillece JD, Kaas RS, Engelthaler DM, Bortolaia V, Pearson T, Waters AE, Upadhyay BP, Shrestha SD, Adhikari S, Shakya G, Keim PS, Aarestrup FM.

MBio. 2011 Sep 1;2(4):e00157-11. doi: 10.1128/mBio.00157-11. Print 2011.

46.

The spatial heterogeneity between Japanese encephalitis incidence distribution and environmental variables in Nepal.

Impoinvil DE, Solomon T, Schluter WW, Rayamajhi A, Bichha RP, Shakya G, Caminade C, Baylis M.

PLoS One. 2011;6(7):e22192. doi: 10.1371/journal.pone.0022192. Epub 2011 Jul 21.

47.

Developing rubella vaccination policy in Nepal--results from rubella surveillance and seroprevalence and congenital rubella syndrome studies.

Upreti SR, Thapa K, Pradhan YV, Shakya G, Sapkota YD, Anand A, Taylor T, Mach O, Reef S, Pattamadilok S, Liyanage J, O'Connor P, Sedai T, Bhandary SR, Partridge J, Schluter W.

J Infect Dis. 2011 Jul;204 Suppl 1:S433-8. doi: 10.1093/infdis/jir078.

PMID:
21666196
48.

Structural and biochemical analyses of regio- and stereospecificities observed in a type II polyketide ketoreductase.

Javidpour P, Korman TP, Shakya G, Tsai SC.

Biochemistry. 2011 May 31;50(21):4638-49. doi: 10.1021/bi200335f. Epub 2011 May 4.

49.

Outbreak of pandemic influenza A/H1N1 2009 in Nepal.

Adhikari BR, Shakya G, Upadhyay BP, Prakash Kc K, Shrestha SD, Dhungana GR.

Virol J. 2011 Mar 23;8:133. doi: 10.1186/1743-422X-8-133.

50.

A growing global network's role in outbreak response: AFHSC-GEIS 2008-2009.

Johns MC, Burke RL, Vest KG, Fukuda M, Pavlin JA, Shrestha SK, Schnabel DC, Tobias S, Tjaden JA, Montgomery JM, Faix DJ, Duffy MR, Cooper MJ, Sanchez JL, Blazes DL; AFHSC-GEIS Outbreak Response Writing Group, Wangchuk S, Dorji T, Gibbons R, Iamsirithaworn S, Richardson J, Buathong R, Jarman R, Yoon IK, Shakya G, Ofula V, Coldren R, Bulimo W, Sang R, Omariba D, Obura B, Mwala D, Kasper M, Brice G, Williams M, Yasuda C, Barthel RV, Pimentel G, Meyers C, Kammerer P, Baynes DE, Metzgar D, Hawksworth A, Blair P, Ellorin M, Coon R, Macintosh V, Burwell K, Macias E, Palys T, Jerke K.

BMC Public Health. 2011 Mar 4;11 Suppl 2:S3. doi: 10.1186/1471-2458-11-S2-S3. Review.

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