Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 177


An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases.

Roy NK, Parama D, Banik K, Bordoloi D, Devi AK, Thakur KK, Padmavathi G, Shakibaei M, Fan L, Sethi G, Kunnumakkara AB.

Int J Mol Sci. 2019 Aug 22;20(17). pii: E4101. doi: 10.3390/ijms20174101. Review.


Cancer drug development: The missing links.

Kunnumakkara AB, Bordoloi D, Sailo BL, Roy NK, Thakur KK, Banik K, Shakibaei M, Gupta SC, Aggarwal BB.

Exp Biol Med (Maywood). 2019 May;244(8):663-689. doi: 10.1177/1535370219839163. Epub 2019 Apr 8.


Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol.

Buhrmann C, Yazdi M, Popper B, Kunnumakkara AB, Aggarwal BB, Shakibaei M.

Nutrients. 2019 Mar 26;11(3). pii: E704. doi: 10.3390/nu11030704.


Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it.

Buhrmann C, Yazdi M, Popper B, Shayan P, Goel A, Aggarwal BB, Shakibaei M.

Exp Biol Med (Maywood). 2019 Jan;244(1):1-12. doi: 10.1177/1535370218824538. Epub 2019 Jan 19.


Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.

Buhrmann C, Yazdi M, Popper B, Shayan P, Goel A, Aggarwal BB, Shakibaei M.

Nutrients. 2018 Jul 12;10(7). pii: E888. doi: 10.3390/nu10070888.


Dietary nutraceuticals as backbone for bone health.

Pandey MK, Gupta SC, Karelia D, Gilhooley PJ, Shakibaei M, Aggarwal BB.

Biotechnol Adv. 2018 Nov 1;36(6):1633-1648. doi: 10.1016/j.biotechadv.2018.03.014. Epub 2018 Mar 27. Review.


Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.

Buhrmann C, Popper B, Aggarwal BB, Shakibaei M.

PLoS One. 2017 Nov 2;12(11):e0186993. doi: 10.1371/journal.pone.0186993. eCollection 2017.


Accessibility of axonal G protein coupled mu-opioid receptors requires conceptual changes of axonal membrane targeting for pain modulation.

Mousa SA, Shaqura M, Al-Madol M, Tafelski S, Khalefa BI, Shakibaei M, Schäfer M.

J Control Release. 2017 Dec 28;268:352-363. doi: 10.1016/j.jconrel.2017.10.016. Epub 2017 Oct 17.


Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.

Buhrmann C, Shayan P, Goel A, Shakibaei M.

Nutrients. 2017 Sep 27;9(10). pii: E1073. doi: 10.3390/nu9101073.


Pathological alterations in liver injury following congestive heart failure induced by volume overload in rats.

Shaqura M, Mohamed DM, Aboryag NB, Bedewi L, Dehe L, Treskatsch S, Shakibaei M, Schäfer M, Mousa SA.

PLoS One. 2017 Sep 21;12(9):e0184161. doi: 10.1371/journal.pone.0184161. eCollection 2017.


Histopathological Changes in the Kidney following Congestive Heart Failure by Volume Overload in Rats.

Aboryag NB, Mohamed DM, Dehe L, Shaqura M, Treskatsch S, Shakibaei M, Schäfer M, Mousa SA.

Oxid Med Cell Longev. 2017;2017:6894040. doi: 10.1155/2017/6894040. Epub 2017 Jul 31.


Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load.

Dex S, Alberton P, Willkomm L, Söllradl T, Bago S, Milz S, Shakibaei M, Ignatius A, Bloch W, Clausen-Schaumann H, Shukunami C, Schieker M, Docheva D.

EBioMedicine. 2017 Jun;20:240-254. doi: 10.1016/j.ebiom.2017.05.003. Epub 2017 May 5.


Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects.

Shaqura M, Li X, Al-Khrasani M, Shakibaei M, Tafelski S, Fürst S, Beyer A, Kawata M, Schäfer M, Mousa SA.

Neuropharmacology. 2016 Dec;111:1-13. doi: 10.1016/j.neuropharm.2016.08.019. Epub 2016 Aug 21.


Effect of platelet mediator concentrate (PMC) on Achilles tenocytes: an in vitro study.

Arslan E, Nellesen T, Bayer A, Prescher A, Lippross S, Nebelung S, Jahr H, Jaeger C, Huebner WD, Fischer H, Stoffel M, Shakibaei M, Pufe T, Tohidnezhad M.

BMC Musculoskelet Disord. 2016 Jul 22;17:307. doi: 10.1186/s12891-016-1160-2.


Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells.

Buhrmann C, Shayan P, Popper B, Goel A, Shakibaei M.

Nutrients. 2016 Mar 5;8(3):145. doi: 10.3390/nu8030145.


Protein kinase C-mediated mu-opioid receptor phosphorylation and desensitization in rats, and its prevention during early diabetes.

Mousa SA, Shaqura M, Winkler J, Khalefa BI, Al-Madol MA, Shakibaei M, Schulz S, Schäfer M.

Pain. 2016 Apr;157(4):910-21. doi: 10.1097/j.pain.0000000000000459.


Evidence for MOR on cell membrane, sarcoplasmatic reticulum and mitochondria in left ventricular myocardium in rats.

Treskatsch S, Shaqura M, Dehe L, Roepke TK, Shakibaei M, Schäfer M, Mousa SA.

Heart Vessels. 2016 Aug;31(8):1380-8. doi: 10.1007/s00380-015-0784-8. Epub 2015 Dec 19.


Upregulation of the kappa opioidergic system in left ventricular rat myocardium in response to volume overload: Adaptive changes of the cardiac kappa opioid system in heart failure.

Treskatsch S, Shaqura M, Dehe L, Feldheiser A, Roepke TK, Shakibaei M, Spies CD, Schäfer M, Mousa SA.

Pharmacol Res. 2015 Dec;102:33-41. doi: 10.1016/j.phrs.2015.09.005. Epub 2015 Sep 10.


Identification and characterization of a compound from Cuminum cyminum essential oil with antifibrilation and cytotoxic effect.

Morshedi D, Kesejini TS, Aliakbari F, Karami-Osboo R, Shakibaei M, Marvian AT, Khalifeh M, Soroosh M.

Res Pharm Sci. 2014 Nov-Dec;9(6):431-43.


Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.

Buhrmann C, Shayan P, Kraehe P, Popper B, Goel A, Shakibaei M.

Biochem Pharmacol. 2015 Nov 1;98(1):51-68. doi: 10.1016/j.bcp.2015.08.105. Epub 2015 Aug 24.


Ultrastructural changes associated with myocardial apoptosis, in failing rat hearts induced by volume overload.

Treskatsch S, Shakibaei M, Feldheiser A, Shaqura M, Dehe L, Roepke TK, Spies C, Schäfer M, Mousa SA.

Int J Cardiol. 2015 Oct 15;197:327-32. doi: 10.1016/j.ijcard.2015.06.067. Epub 2015 Jun 28.


Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer.

Shakibaei M, Kraehe P, Popper B, Shayan P, Goel A, Buhrmann C.

BMC Cancer. 2015 Apr 10;15:250. doi: 10.1186/s12885-015-1291-0.


Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer.

Toden S, Okugawa Y, Buhrmann C, Nattamai D, Anguiano E, Baldwin N, Shakibaei M, Boland CR, Goel A.

Cancer Prev Res (Phila). 2015 May;8(5):431-43. doi: 10.1158/1940-6207.CAPR-14-0354. Epub 2015 Feb 23.


Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer.

Toden S, Okugawa Y, Jascur T, Wodarz D, Komarova NL, Buhrmann C, Shakibaei M, Boland CR, Goel A.

Carcinogenesis. 2015 Mar;36(3):355-67. doi: 10.1093/carcin/bgv006. Epub 2015 Feb 4.


Cellular localization and adaptive changes of the cardiac delta opioid receptor system in an experimental model of heart failure in rats.

Treskatsch S, Feldheiser A, Shaqura M, Dehe L, Habazettl H, Röpke TK, Shakibaei M, Schäfer M, Spies CD, Mousa SA.

Heart Vessels. 2016 Feb;31(2):241-50. doi: 10.1007/s00380-014-0620-6. Epub 2015 Jan 1.


Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.

Buhrmann C, Kraehe P, Lueders C, Shayan P, Goel A, Shakibaei M.

PLoS One. 2014 Sep 19;9(9):e107514. doi: 10.1371/journal.pone.0107514. eCollection 2014.


Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.

Buhrmann C, Busch F, Shayan P, Shakibaei M.

J Biol Chem. 2014 Aug 8;289(32):22048-62. doi: 10.1074/jbc.M114.568790. Epub 2014 Jun 24.


New insights into mechanisms of opioid inhibitory effects on capsaicin-induced TRPV1 activity during painful diabetic neuropathy.

Shaqura M, Khalefa BI, Shakibaei M, Zöllner C, Al-Khrasani M, Fürst S, Schäfer M, Mousa SA.

Neuropharmacology. 2014 Oct;85:142-50. doi: 10.1016/j.neuropharm.2014.05.026. Epub 2014 May 24.


A modified approach to induce predictable congestive heart failure by volume overload in rats.

Treskatsch S, Feldheiser A, Rosin AT, Sifringer M, Habazettl H, Mousa SA, Shakibaei M, Schäfer M, Spies CD.

PLoS One. 2014 Jan 31;9(1):e87531. doi: 10.1371/journal.pone.0087531. eCollection 2014.


Curcumin chemosensitizes 5-fluorouracil resistant MMR-deficient human colon cancer cells in high density cultures.

Shakibaei M, Buhrmann C, Kraehe P, Shayan P, Lueders C, Goel A.

PLoS One. 2014 Jan 3;9(1):e85397. doi: 10.1371/journal.pone.0085397. eCollection 2014.


Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes.

Buhrmann C, Shayan P, Aggarwal BB, Shakibaei M.

Arthritis Res Ther. 2013;15(6):R202.


Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis.

Mobasheri A, Shakibaei M.

Ann N Y Acad Sci. 2013 Jul;1290:59-66. doi: 10.1111/nyas.12145. Review.


Large scale expansion of human umbilical cord cells in a rotating bed system bioreactor for cardiovascular tissue engineering applications.

Reichardt A, Polchow B, Shakibaei M, Henrich W, Hetzer R, Lueders C.

Open Biomed Eng J. 2013 Jun 14;7:50-61. doi: 10.2174/1874120701307010050. Print 2013.


Reduced number, G protein coupling, and antinociceptive efficacy of spinal mu-opioid receptors in diabetic rats are reversed by nerve growth factor.

Shaqura M, Khalefa BI, Shakibaei M, Winkler J, Al-Khrasani M, Fürst S, Mousa SA, Schäfer M.

J Pain. 2013 Jul;14(7):720-30. doi: 10.1016/j.jpain.2013.01.776. Epub 2013 Apr 24.


Is tendinitis an inflammatory disease initiated and driven by pro-inflammatory cytokines such as interleukin 1β?

Mobasheri A, Shakibaei M.

Histol Histopathol. 2013 Aug;28(8):955-64. doi: 10.14670/HH-28.955. Epub 2013 Mar 6. Review.


Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways.

Shakibaei M, Mobasheri A, Lueders C, Busch F, Shayan P, Goel A.

PLoS One. 2013;8(2):e57218. doi: 10.1371/journal.pone.0057218. Epub 2013 Feb 22.


Rab7 silencing prevents μ-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy.

Mousa SA, Shaqura M, Khalefa BI, Zöllner C, Schaad L, Schneider J, Shippenberg TS, Richter JF, Hellweg R, Shakibaei M, Schäfer M.

Diabetes. 2013 Apr;62(4):1308-19. doi: 10.2337/db12-0590. Epub 2012 Dec 10.


Resveratrol modulates interleukin-1β-induced phosphatidylinositol 3-kinase and nuclear factor κB signaling pathways in human tenocytes.

Busch F, Mobasheri A, Shayan P, Lueders C, Stahlmann R, Shakibaei M.

J Biol Chem. 2012 Nov 2;287(45):38050-63. doi: 10.1074/jbc.M112.377028. Epub 2012 Aug 30.


Effects of mycophenolic acid alone and in combination with its metabolite mycophenolic acid glucuronide on rat embryos in vitro.

Schmidt F, Eckardt K, Shakibaei M, Glander P, Stahlmann R.

Arch Toxicol. 2013 Feb;87(2):361-70. doi: 10.1007/s00204-012-0922-3. Epub 2012 Aug 23.


Midkine acts as proangiogenic cytokine in hypoxia-induced angiogenesis.

Weckbach LT, Groesser L, Borgolte J, Pagel JI, Pogoda F, Schymeinsky J, Müller-Höcker J, Shakibaei M, Muramatsu T, Deindl E, Walzog B.

Am J Physiol Heart Circ Physiol. 2012 Aug 15;303(4):H429-38. doi: 10.1152/ajpheart.00934.2011. Epub 2012 Jun 15.


Sirt-1 is required for the inhibition of apoptosis and inflammatory responses in human tenocytes.

Busch F, Mobasheri A, Shayan P, Stahlmann R, Shakibaei M.

J Biol Chem. 2012 Jul 27;287(31):25770-81. doi: 10.1074/jbc.M112.355420. Epub 2012 Jun 11.


Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.

Mobasheri A, Henrotin Y, Biesalski HK, Shakibaei M.

Int J Mol Sci. 2012;13(4):4202-32. doi: 10.3390/ijms13044202. Epub 2012 Mar 30. Review.


Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation.

Shakibaei M, Shayan P, Busch F, Aldinger C, Buhrmann C, Lueders C, Mobasheri A.

PLoS One. 2012;7(4):e35712. doi: 10.1371/journal.pone.0035712. Epub 2012 Apr 23.


Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes.

Shakibaei M, Allaway D, Nebrich S, Mobasheri A.

Evid Based Complement Alternat Med. 2012;2012:509383. doi: 10.1155/2012/509383. Epub 2012 Mar 14.


Treatment of full thickness cartilage defects in human knees with Autologous Chondrocyte Transplantation.

Nazem K, Safdarian A, Fesharaki M, Moulavi F, Motififard M, Zarezadeh A, Shakibaei M, Esfandiari E, Nasr-Esfahani MH.

J Res Med Sci. 2011 Jul;16(7):855-61.


IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.

Montaseri A, Busch F, Mobasheri A, Buhrmann C, Aldinger C, Rad JS, Shakibaei M.

PLoS One. 2011;6(12):e28663. doi: 10.1371/journal.pone.0028663. Epub 2011 Dec 14.


Anti-inflammatory and anti-catabolic effects of TENDOACTIVE® on human tenocytes in vitro.

Shakibaei M, Buhrmann C, Mobasheri A.

Histol Histopathol. 2011 Sep;26(9):1173-85. doi: 10.14670/HH-26.1173.


Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway.

Buhrmann C, Mobasheri A, Busch F, Aldinger C, Stahlmann R, Montaseri A, Shakibaei M.

J Biol Chem. 2011 Aug 12;286(32):28556-66. doi: 10.1074/jbc.M111.256180. Epub 2011 Jun 13.


Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro.

Shakibaei M, Mobasheri A, Buhrmann C.

Genes Nutr. 2011 May;6(2):171-9. doi: 10.1007/s12263-010-0179-5. Epub 2010 May 25.

Supplemental Content

Loading ...
Support Center