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Items: 1 to 50 of 88

1.

Elderly apolipoprotein E‑/‑ mice with advanced atherosclerotic lesions in the aorta do not develop Alzheimer's disease-like pathologies.

Shnerb Ganor R, Harats D, Schiby G, Rosenblatt K, Lubitz I, Shaish A, Salomon O.

Mol Med Rep. 2018 Feb;17(2):2488-2492. doi: 10.3892/mmr.2017.8127. Epub 2017 Nov 21.

PMID:
29207114
2.

Interleukin 1-alpha deficiency increases the expression of Follicle-stimulating hormone receptors in granulosa cells.

Uri-Belapolsky S, Miller I, Shaish A, Levi M, Harats D, Ninio-Many L, Kamari Y, Shalgi R.

Mol Reprod Dev. 2017 Jun;84(6):460-467. doi: 10.1002/mrd.22799. Epub 2017 Apr 17.

PMID:
28337831
3.

Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins.

Boehm-Cagan A, Bar R, Harats D, Shaish A, Levkovitz H, Bielicki JK, Johansson JO, Michaelson DM.

PLoS One. 2016 Nov 8;11(11):e0166195. doi: 10.1371/journal.pone.0166195. eCollection 2016.

4.

9-cis β-Carotene Increased Cholesterol Efflux to HDL in Macrophages.

Bechor S, Zolberg Relevy N, Harari A, Almog T, Kamari Y, Ben-Amotz A, Harats D, Shaish A.

Nutrients. 2016 Jul 19;8(7). pii: E435. doi: 10.3390/nu8070435.

5.

Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia.

Grosskopf I, Shaish A, Charach G, Harats D, Kamari Y.

Horm Metab Res. 2016 Apr;48(4):257-62. doi: 10.1055/s-0035-1565180. Epub 2016 Feb 5.

PMID:
26849821
6.

Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice.

Shnerb Ganor R, Harats D, Schiby G, Gailani D, Levkovitz H, Avivi C, Tamarin I, Shaish A, Salomon O.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):475-81. doi: 10.1161/ATVBAHA.115.306954. Epub 2016 Jan 21.

7.

Thoracic Duct Narrowing-Innovative Technique Restraining Weight Gain in Rats.

Rosenzweig B, Barshack I, Harats D, Shaish A.

Obes Surg. 2015 Dec;25(12):2443-50. doi: 10.1007/s11695-015-1917-y.

PMID:
26446490
8.

Interleukin-1α deficiency attenuates endoplasmic reticulum stress-induced liver damage and CHOP expression in mice.

Kandel-Kfir M, Almog T, Shaish A, Shlomai G, Anafi L, Avivi C, Barshack I, Grosskopf I, Harats D, Kamari Y.

J Hepatol. 2015 Oct;63(4):926-33. doi: 10.1016/j.jhep.2015.05.012. Epub 2015 May 27.

PMID:
26022690
9.

The Effect of Klotho Treatment on Atherogenesis, Blood Pressure, and Metabolic Parameters in Experimental Rodent Models.

Kamari Y, Fingrut O, Shaish A, Almog T, Kandel-Kfir M, Harats D, Rubinek T, Wolf I.

Horm Metab Res. 2016 Mar;48(3):196-200. doi: 10.1055/s-0035-1549879. Epub 2015 May 7.

PMID:
25951321
10.

Vitamin A-deficient diet accelerated atherogenesis in apolipoprotein E(-/-) mice and dietary β-carotene prevents this consequence.

Relevy NZ, Harats D, Harari A, Ben-Amotz A, Bitzur R, Rühl R, Shaish A.

Biomed Res Int. 2015;2015:758723. doi: 10.1155/2015/758723. Epub 2015 Feb 23.

11.

Knockdown of interleukin-1α does not attenuate LPS-induced production of interleukin-1β in mouse macrophages.

Almog T, Kandel-Kfir M, Shaish A, Dissen M, Shlomai G, Voronov E, Apte RN, Harats D, Kamari Y.

Cytokine. 2015 May;73(1):138-43. doi: 10.1016/j.cyto.2015.01.029. Epub 2015 Mar 6.

PMID:
25748836
12.

The inhibition of macrophage foam cell formation by 9-cis β-carotene is driven by BCMO1 activity.

Zolberg Relevy N, Bechor S, Harari A, Ben-Amotz A, Kamari Y, Harats D, Shaish A.

PLoS One. 2015 Jan 28;10(1):e0115272. doi: 10.1371/journal.pone.0115272. eCollection 2015.

13.

Experimental myocardial infarction induces altered regulatory T cell hemostasis, and adoptive transfer attenuates subsequent remodeling.

Sharir R, Semo J, Shimoni S, Ben-Mordechai T, Landa-Rouben N, Maysel-Auslender S, Shaish A, Entin-Meer M, Keren G, George J.

PLoS One. 2014 Dec 1;9(12):e113653. doi: 10.1371/journal.pone.0113653. eCollection 2014.

14.

Interleukin-1 deficiency prolongs ovarian lifespan in mice.

Uri-Belapolsky S, Shaish A, Eliyahu E, Grossman H, Levi M, Chuderland D, Ninio-Many L, Hasky N, Shashar D, Almog T, Kandel-Kfir M, Harats D, Shalgi R, Kamari Y.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12492-7. doi: 10.1073/pnas.1323955111. Epub 2014 Aug 11.

15.

Regulatory T cells influence blood flow recovery in experimental hindlimb ischaemia in an IL-10-dependent manner.

Sharir R, Semo J, Shaish A, Landa-Rouben N, Entin-Meer M, Keren G, George J.

Cardiovasc Res. 2014 Sep 1;103(4):585-96. doi: 10.1093/cvr/cvu159. Epub 2014 Jun 25.

PMID:
24966183
16.

Lack of interleukin-1α in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice.

Olteanu S, Kandel-Kfir M, Shaish A, Almog T, Shemesh S, Barshack I, Apte RN, Harats D, Kamari Y.

Dig Liver Dis. 2014 May;46(5):433-9. doi: 10.1016/j.dld.2014.01.156. Epub 2014 Feb 26.

PMID:
24582082
17.

Non-viability of crossing the Alzheimer mouse model Tg2576 with the type 2 diabetes mouse model ob/ob.

Lubitz I, Haroutunian V, Katsel P, Leroith D, Landa N, Castel D, Shaish A, Shnerb R, Schnaider-Beeri M.

Neurobiol Aging. 2014 Jul;35(7):e19-20. doi: 10.1016/j.neurobiolaging.2014.01.138. Epub 2014 Jan 31. No abstract available.

PMID:
24581479
18.

Low molecular weight heparin-induced increase in chylomicron-remnants clearance, is associated with decreased plasma TNF-α level and increased hepatic lipase activity.

Grosskopf I, Shaish A, Ray A, Harats D, Kamari Y.

Thromb Res. 2014 Apr;133(4):688-92. doi: 10.1016/j.thromres.2014.01.019. Epub 2014 Jan 21.

PMID:
24525311
19.

Prevention of atherosclerosis progression by 9-cis-β-carotene rich alga Dunaliella in apoE-deficient mice.

Harari A, Abecassis R, Relevi N, Levi Z, Ben-Amotz A, Kamari Y, Harats D, Shaish A.

Biomed Res Int. 2013;2013:169517. doi: 10.1155/2013/169517. Epub 2013 Sep 23.

20.

Effect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts.

Kriska T, Cepura C, Siangjong L, Wan TC, Auchampach JA, Shaish A, Haratz D, Kumar G, Falck JR, Gauthier KM, Campbell WB.

Prostaglandins Other Lipid Mediat. 2013 Oct;106:8-15. doi: 10.1016/j.prostaglandins.2013.07.002. Epub 2013 Jul 16.

21.

Treatment with 9-cis β-carotene-rich powder in patients with retinitis pigmentosa: a randomized crossover trial.

Rotenstreich Y, Belkin M, Sadetzki S, Chetrit A, Ferman-Attar G, Sher I, Harari A, Shaish A, Harats D.

JAMA Ophthalmol. 2013 Aug;131(8):985-92.

PMID:
23700011
22.

9-cis-rich β-carotene powder of the alga Dunaliella reduces the severity of chronic plaque psoriasis: a randomized, double-blind, placebo-controlled clinical trial.

Greenberger S, Harats D, Salameh F, Lubish T, Harari A, Trau H, Shaish A.

J Am Coll Nutr. 2012 Oct;31(5):320-6.

PMID:
23529989
23.

Apolipoprotein A-V modulates multiple atherogenic mechanisms in a mouse model of disturbed clearance of triglyceride-rich lipoproteins.

Grosskopf I, Shaish A, Afek A, Shemesh S, Harats D, Kamari Y.

Atherosclerosis. 2012 Sep;224(1):75-83. doi: 10.1016/j.atherosclerosis.2012.04.011. Epub 2012 May 29.

PMID:
22809445
24.

Low-dose calcitriol decreases aortic renin, blood pressure, and atherosclerosis in apoe-null mice.

Ish-Shalom M, Sack J, Vechoropoulos M, Shaish A, Entin-Meer M, Kamari Y, Maysel-Auslender S, Keren G, Harats D, Stern N, Tordjman K.

J Atheroscler Thromb. 2012;19(5):422-34. Epub 2012 Apr 16.

25.

Alteration of lipids and the transcription of lipid-related genes in myelodysplastic syndromes via a TP53-related pathway.

Ellis MH, Baraf L, Shaish A, Har-Zahav A, Harats D, Ashur-Fabian O.

Exp Hematol. 2012 Jul;40(7):540-547.e1. doi: 10.1016/j.exphem.2012.02.003. Epub 2012 Feb 27.

PMID:
22381680
26.

Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice.

Shemesh S, Kamari Y, Shaish A, Olteanu S, Kandel-Kfir M, Almog T, Grosskopf I, Apte RN, Harats D.

Atherosclerosis. 2012 Jun;222(2):329-36. doi: 10.1016/j.atherosclerosis.2011.12.010. Epub 2011 Dec 17.

PMID:
22236482
27.

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice.

Kamari Y, Shaish A, Vax E, Shemesh S, Kandel-Kfir M, Arbel Y, Olteanu S, Barshack I, Dotan S, Voronov E, Dinarello CA, Apte RN, Harats D.

J Hepatol. 2011 Nov;55(5):1086-94. doi: 10.1016/j.jhep.2011.01.048. Epub 2011 Feb 24.

28.

Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α.

Kamari Y, Shaish A, Shemesh S, Vax E, Grosskopf I, Dotan S, White M, Voronov E, Dinarello CA, Apte RN, Harats D.

Biochem Biophys Res Commun. 2011 Feb 11;405(2):197-203. doi: 10.1016/j.bbrc.2011.01.008. Epub 2011 Jan 8.

PMID:
21219852
29.

Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic.

Leikin-Frenkel A, Gonen A, Shaish A, Goldiner I, Leikin-Gobbi D, Konikoff FM, Harats D, Gilat T.

Arch Med Res. 2010 Aug;41(6):397-404. doi: 10.1016/j.arcmed.2010.09.001.

PMID:
21044742
30.

Effects of hypoxia-inducible factor-1alpha overexpression in pregnant mice: possible implications for preeclampsia and intrauterine growth restriction.

Tal R, Shaish A, Barshack I, Polak-Charcon S, Afek A, Volkov A, Feldman B, Avivi C, Harats D.

Am J Pathol. 2010 Dec;177(6):2950-62. doi: 10.2353/ajpath.2010.090800. Epub 2010 Oct 15.

31.

apoB and apobec1, two genes key to lipid metabolism, are transcriptionally regulated by p53.

Ashur-Fabian O, Har-Zahav A, Shaish A, Wiener Amram H, Margalit O, Weizer-Stern O, Dominissini D, Harats D, Amariglio N, Rechavi G.

Cell Cycle. 2010 Sep 15;9(18):3761-70. Epub 2010 Sep 12.

PMID:
20890106
32.

Treatment of a retinal dystrophy, fundus albipunctatus, with oral 9-cis-{beta}-carotene.

Rotenstreich Y, Harats D, Shaish A, Pras E, Belkin M.

Br J Ophthalmol. 2010 May;94(5):616-21. doi: 10.1136/bjo.2009.167049. Epub 2009 Dec 2.

PMID:
19955196
33.

Should all diabetic patients be treated with a statin?

Kamari Y, Bitzur R, Cohen H, Shaish A, Harats D.

Diabetes Care. 2009 Nov;32 Suppl 2:S378-83. doi: 10.2337/dc09-S344. Review. No abstract available.

34.

Triglycerides and HDL cholesterol: stars or second leads in diabetes?

Bitzur R, Cohen H, Kamari Y, Shaish A, Harats D.

Diabetes Care. 2009 Nov;32 Suppl 2:S373-7. doi: 10.2337/dc09-S343. Review. No abstract available.

35.

Systemic administration of radiation-potentiated anti-angiogenic gene therapy against primary and metastatic cancer based on transcriptionally controlled HSV-TK.

Hodish I, Tal R, Shaish A, Varda-Bloom N, Greenberger S, Rauchwerger A, Breitbart E, Bangio L, Ben-Shushan D, Pfeffer R, Feder B, Waitsman A, Barshack I, Goldberg I, Mazaki-Tovi S, Peled M, Harats D.

Cancer Biol Ther. 2009 Mar;8(5):424-32. Epub 2009 Mar 19.

PMID:
19276657
36.

Systemic administration of a conditionally replicating adenovirus, targeted to angiogenesis, reduced lung metastases burden in cotton rats.

Peled M, Shaish A, Katav A, Greenberger S, Barshack I, Tal R, Bangio L, Breitbart E, Harats D.

Clin Cancer Res. 2009 Mar 1;15(5):1664-73. doi: 10.1158/1078-0432.CCR-08-1670. Epub 2009 Feb 24.

37.

Specific induction of tumor neovasculature death by modified murine PPE-1 promoter armed with HSV-TK.

Varda-Bloom N, Hodish I, Shaish A, Greenberger S, Tal R, Feder B, Roitelman J, Breitbart E, Bangio L, Barshack I, Pfeffer R, Harats D.

Pathobiology. 2008;75(6):346-55. doi: 10.1159/000164219. Epub 2008 Dec 15.

38.

Endothelial-targeted Gene Transfer of Hypoxia-inducible Factor-1α Augments Ischemic Neovascularization Following Systemic Administration.

Tal R, Shaish A, Rofe K, Feige E, Varda-Bloom N, Afek A, Barshack I, Bangio L, Hodish I, Greenberger S, Peled M, Breitbart E, Harats D.

Mol Ther. 2008 Dec;16(12):1927-1936. doi: 10.1038/mt.2008.191. Epub 2016 Dec 8.

PMID:
28189008
39.

A 9-cis beta-carotene-enriched diet inhibits atherogenesis and fatty liver formation in LDL receptor knockout mice.

Harari A, Harats D, Marko D, Cohen H, Barshack I, Kamari Y, Gonen A, Gerber Y, Ben-Amotz A, Shaish A.

J Nutr. 2008 Oct;138(10):1923-30.

PMID:
18806102
40.

Endothelial-targeted gene transfer of hypoxia-inducible factor-1alpha augments ischemic neovascularization following systemic administration.

Tal R, Shaish A, Rofe K, Feige E, Varda-Bloom N, Afek A, Barshack I, Bangio L, Hodish I, Greenberger S, Peled M, Breitbart E, Harats D.

Mol Ther. 2008 Dec;16(12):1927-36. doi: 10.1038/mt.2008.191. Epub 2008 Sep 16.

41.

A carotenoid algal preparation containing phytoene and phytofluene inhibited LDL oxidation in vitro.

Shaish A, Harari A, Kamari Y, Soudant E, Harats D, Ben-Amotz A.

Plant Foods Hum Nutr. 2008 Jun;63(2):83-6. doi: 10.1007/s11130-008-0075-y. Epub 2008 Apr 29.

PMID:
18443908
42.

Activation of C-transactivation domain is essential for optimal HIF-1 alpha-mediated transcriptional and angiogenic effects.

Tal R, Shaish A, Bangio L, Peled M, Breitbart E, Harats D.

Microvasc Res. 2008 May;76(1):1-6. doi: 10.1016/j.mvr.2008.03.002. Epub 2008 Mar 20.

PMID:
18440561
43.

Antiangiogenic systemic gene therapy combined with doxorubicin administration induced caspase 8 and 9-mediated apoptosis in endothelial cells and an anti-metastasis effect.

Peled M, Shaish A, Greenberger S, Katav A, Hodish I, Ben-Shushan D, Barshack I, Mendel I, Frishman L, Tal R, Bangio L, Breitbart E, Harats D.

Cancer Gene Ther. 2008 Aug;15(8):535-42. doi: 10.1038/cgt.2008.20. Epub 2008 Apr 18.

PMID:
18421310
44.

Characterisation of atherosclerotic lesions with scanning electron microscopy (SEM) of wet tissue.

Kamari Y, Cohen H, Shaish A, Bitzur R, Afek A, Shen S, Vainshtein A, Harats D.

Diab Vasc Dis Res. 2008 Mar;5(1):44-7. doi: 10.3132/dvdr.2008.008.

PMID:
18398812
45.

Effect of telmisartan, angiotensin II receptor antagonist, on metabolic profile in fructose-induced hypertensive, hyperinsulinemic, hyperlipidemic rats.

Kamari Y, Harari A, Shaish A, Peleg E, Sharabi Y, Harats D, Grossman E.

Hypertens Res. 2008 Jan;31(1):135-40. doi: 10.1291/hypres.31.135.

PMID:
18360028
46.

Familial Mediterranean fever gene and protection against asthma.

Rabinovitch E, Harats D, Yaron P, Luvish T, Lidar M, Kedem R, Shaish A, Ben-Dov I, Livneh A.

Ann Allergy Asthma Immunol. 2007 Dec;99(6):517-21. doi: 10.1016/S1081-1206(10)60380-8.

PMID:
18219832
47.

Rifampicin-induced CYP3A4 activation in CTX patients cannot replace chenodeoxycholic acid treatment.

Szalat A, Gershkovich P, Ben-Ari A, Shaish A, Liberman Y, Boutboul E, Gotkine M, Hoffman A, Harats D, Leitersdorf E, Meiner V.

Biochim Biophys Acta. 2007 Jul;1771(7):839-44. Epub 2007 May 1.

PMID:
17553741
48.

Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism.

Kamari Y, Werman-Venkert R, Shaish A, Werman A, Harari A, Gonen A, Voronov E, Grosskopf I, Sharabi Y, Grossman E, Iwakura Y, Dinarello CA, Apte RN, Harats D.

Atherosclerosis. 2007 Nov;195(1):31-8. Epub 2006 Dec 14.

PMID:
17173923
49.

Vascular wall maturation and prolonged angiogenic effect by endothelial-specific platelet-derived growth factor expression.

Levanon K, Varda-Bloom N, Greenberger S, Barshack I, Goldberg I, Orenstein A, Breitbart E, Shaish A, Harats D.

Pathobiology. 2006;73(3):149-58.

PMID:
17085959
50.

Endothelin B receptor antagonist increases preproendothelin-1 transcription in bovine aortic endothelial cells and in vivo.

Peled M, Shaish A, Frishman L, Cohen H, Tal R, Harats D.

J Cardiovasc Pharmacol. 2006 May;47(5):668-72.

PMID:
16775506

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