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Items: 1 to 50 of 161

1.

Cardioprotection from stress conditions by weak magnetic fields in the Schumann Resonance band.

Elhalel G, Price C, Fixler D, Shainberg A.

Sci Rep. 2019 Feb 7;9(1):1645. doi: 10.1038/s41598-018-36341-z.

2.

Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model.

Trifonov L, Nudelman V, Zhenin M, Matsree E, Afri M, Schmerling B, Cohen G, Jozwiak K, Weitman M, Korshin E, Senderowitz H, Shainberg A, Hochhauser E, Gruzman A.

J Med Chem. 2018 Dec 3. doi: 10.1021/acs.jmedchem.8b01471. [Epub ahead of print]

PMID:
30507195
3.

PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis.

Waldman M, Nudelman V, Shainberg A, Abraham NG, Kornwoski R, Aravot D, Arad M, Hochhauser E.

Exp Cell Res. 2018 Dec 15;373(1-2):112-118. doi: 10.1016/j.yexcr.2018.10.003. Epub 2018 Oct 23.

PMID:
30359575
4.

Nitric oxide is cytoprotective to breast cancer spheroids vulnerable to estrogen-induced apoptosis.

Shafran Y, Zurgil N, Ravid-Hermesh O, Sobolev M, Afrimzon E, Hakuk Y, Shainberg A, Deutsch M.

Oncotarget. 2017 Oct 7;8(65):108890-108911. doi: 10.18632/oncotarget.21610. eCollection 2017 Dec 12.

5.

Muscle Response to Complete Peripheral Nerve Injury: Changes of Acetylcholine Receptor and Creatine Kinase Activity over Time.

Rochkind S, Shainberg A.

J Reconstr Microsurg. 2017 Jun;33(5):352-357. doi: 10.1055/s-0037-1598619. Epub 2017 Feb 20.

PMID:
28561186
6.

Viral delivered gene therapy to treat catecholaminergic polymorphic ventricular tachycardia (CPVT2) in mouse models.

Kurtzwald-Josefson E, Yadin D, Harun-Khun S, Waldman M, Aravot D, Shainberg A, Eldar M, Hochhauser E, Arad M.

Heart Rhythm. 2017 Jul;14(7):1053-1060. doi: 10.1016/j.hrthm.2017.03.025. Epub 2017 Mar 20.

PMID:
28336343
7.

Silencing cardiomyocyte TLR4 reduces injury following hypoxia.

Avlas O, Srara S, Shainberg A, Aravot D, Hochhauser E.

Exp Cell Res. 2016 Nov 1;348(2):115-122. doi: 10.1016/j.yexcr.2016.07.020. Epub 2016 Jul 19.

PMID:
27448767
8.

Weak electromagnetic fields alter Ca(2+) handling and protect against hypoxia-mediated damage in primary newborn rat myotube cultures.

Adler D, Fixler D, Scheinowitz M, Shainberg A, Katz A.

Pflugers Arch. 2016 Aug;468(8):1459-65. doi: 10.1007/s00424-016-1837-2. Epub 2016 May 18.

PMID:
27194243
9.

A PARP1-ERK2 synergism is required for the induction of LTP.

Visochek L, Grigoryan G, Kalal A, Milshtein-Parush H, Gazit N, Slutsky I, Yeheskel A, Shainberg A, Castiel A, Seger R, Langelier MF, Dantzer F, Pascal JM, Segal M, Cohen-Armon M.

Sci Rep. 2016 Apr 28;6:24950. doi: 10.1038/srep24950.

10.

Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection.

Levy E, Kornowski R, Gavrieli R, Fratty I, Greenberg G, Waldman M, Birk E, Shainberg A, Akirov A, Miskin R, Hochhauser E.

PLoS One. 2015 Dec 16;10(12):e0144593. doi: 10.1371/journal.pone.0144593. eCollection 2015.

11.

Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury.

Hochhauser E, Lahat E, Sultan M, Pappo O, Waldman M, Sarne Y, Shainberg A, Gutman M, Safran M, Ben Ari Z.

Cell Physiol Biochem. 2015;36(5):1971-81. doi: 10.1159/000430165. Epub 2015 Jul 17.

12.

TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery.

Avlas O, Bragg A, Fuks A, Nicholson JD, Farkash A, Porat E, Aravot D, Levy-Drummer RS, Cohen C, Shainberg A, Arad M, Hochhauser E.

PLoS One. 2015 Jun 1;10(6):e0120175. doi: 10.1371/journal.pone.0120175. eCollection 2015.

13.

Tumor necrosis factor alpha protects heart cultures against hypoxic damage via activation of PKA and phospholamban to prevent calcium overload.

El-Ani D, Philipchik I, Stav H, Levi M, Zerbib J, Shainberg A.

Can J Physiol Pharmacol. 2014 Nov;92(11):917-25. doi: 10.1139/cjpp-2014-0092. Epub 2014 Aug 28.

PMID:
25349921
14.

Sirtuin 6 protects the heart from hypoxic damage.

Maksin-Matveev A, Kanfi Y, Hochhauser E, Isak A, Cohen HY, Shainberg A.

Exp Cell Res. 2015 Jan 1;330(1):81-90. doi: 10.1016/j.yexcr.2014.07.013. Epub 2014 Jul 24.

PMID:
25066211
15.

Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice.

Kurtzwald-Josefson E, Hochhauser E, Bogachenko K, Harun-Khun S, Katz G, Aravot D, Seidman JG, Seidman CE, Eldar M, Shainberg A, Arad M.

Heart Rhythm. 2014 Aug;11(8):1471-9. doi: 10.1016/j.hrthm.2014.04.030. Epub 2014 Apr 21.

16.

Heme oxygenase-1 induction improves cardiac function following myocardial ischemia by reducing oxidative stress.

Issan Y, Kornowski R, Aravot D, Shainberg A, Laniado-Schwartzman M, Sodhi K, Abraham NG, Hochhauser E.

PLoS One. 2014 Mar 21;9(3):e92246. doi: 10.1371/journal.pone.0092246. eCollection 2014.

17.

Protective effect of laser phototherapy on acetylcholine receptors and creatine kinase activity in denervated muscle.

Rochkind S, Shainberg A.

Photomed Laser Surg. 2013 Oct;31(10):499-504. doi: 10.1089/pho.2013.3537.

PMID:
24102168
18.

Phototherapy and nerve injury: focus on muscle response.

Rochkind S, Geuna S, Shainberg A.

Int Rev Neurobiol. 2013;109:99-109. doi: 10.1016/B978-0-12-420045-6.00004-3. Review.

PMID:
24093608
19.

The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).

Katz G, Shainberg A, Hochhauser E, Kurtzwald-Josefson E, Issac A, El-Ani D, Aravot D, Afek A, Seidman JG, Seidman CE, Eldar M, Arad M.

Biochem Pharmacol. 2013 Dec 1;86(11):1576-83. doi: 10.1016/j.bcp.2013.09.012. Epub 2013 Sep 23.

20.

Popeye domain containing 1 (Popdc1/Bves) is a caveolae-associated protein involved in ischemia tolerance.

Alcalay Y, Hochhauser E, Kliminski V, Dick J, Zahalka MA, Parnes D, Schlesinger H, Abassi Z, Shainberg A, Schindler RF, Brand T, Kessler-Icekson G.

PLoS One. 2013 Sep 16;8(9):e71100. doi: 10.1371/journal.pone.0071100. eCollection 2013.

21.

Bone marrow and nonbone marrow Toll like receptor 4 regulate acute hepatic injury induced by endotoxemia.

Hochhauser E, Avlas O, Fallach R, Bachmetov L, Zemel R, Pappo O, Shainberg A, Ben Ari Z.

PLoS One. 2013 Aug 15;8(8):e73041. doi: 10.1371/journal.pone.0073041. eCollection 2013.

22.

Speckle-based configuration for simultaneous in vitro inspection of mechanical contractions of cardiac myocyte cells.

Golberg M, Fixler D, Shainberg A, Zlochiver S, Micó V, Garcia J, Beiderman Y, Zalevsky Z.

J Biomed Opt. 2013 Oct;18(10):101310. doi: 10.1117/1.JBO.18.10.101310.

PMID:
23856787
23.

Infarct-induced steroidogenic acute regulatory protein: a survival role in cardiac fibroblasts.

Anuka E, Yivgi-Ohana N, Eimerl S, Garfinkel B, Melamed-Book N, Chepurkol E, Aravot D, Zinman T, Shainberg A, Hochhauser E, Orly J.

Mol Endocrinol. 2013 Sep;27(9):1502-17. doi: 10.1210/me.2013-1006. Epub 2013 Jul 5.

24.

P2Y2 receptor agonist with enhanced stability protects the heart from ischemic damage in vitro and in vivo.

Hochhauser E, Cohen R, Waldman M, Maksin A, Isak A, Aravot D, Jayasekara PS, Müller CE, Jacobson KA, Shainberg A.

Purinergic Signal. 2013 Dec;9(4):633-42. doi: 10.1007/s11302-013-9374-3. Epub 2013 Jul 5.

25.

An ultra-low dose of tetrahydrocannabinol provides cardioprotection.

Waldman M, Hochhauser E, Fishbein M, Aravot D, Shainberg A, Sarne Y.

Biochem Pharmacol. 2013 Jun 1;85(11):1626-33. doi: 10.1016/j.bcp.2013.03.014. Epub 2013 Mar 26.

PMID:
23537701
26.

Voltage-driven Ca(2+) binding at the L-type Ca(2+) channel triggers cardiac excitation-contraction coupling prior to Ca(2+) influx.

Gez LS, Hagalili Y, Shainberg A, Atlas D.

Biochemistry. 2012 Dec 4;51(48):9658-66. doi: 10.1021/bi301124a. Epub 2012 Nov 21.

PMID:
23145875
27.

Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice.

Kurtzwald-Josefson E, Hochhauser E, Katz G, Porat E, Seidman JG, Seidman CE, Chepurko Y, Shainberg A, Eldar M, Arad M.

J Appl Physiol (1985). 2012 Dec 1;113(11):1677-83. doi: 10.1152/japplphysiol.00818.2012. Epub 2012 Oct 4.

28.

Correlative analyses of nitric oxide generation rates and nitric oxide synthase levels in individual cells using a modular cell-retaining device.

Shafran Y, Zurgil N, Afrimzon E, Tauber Y, Sobolev M, Shainberg A, Deutsch M.

Anal Chem. 2012 Sep 4;84(17):7315-22. doi: 10.1021/ac202741z. Epub 2012 Aug 17.

PMID:
22839699
29.

Correlation of magnetic AC field on cardiac myocyte Ca(2+) transients at different magnetic DC levels.

Fixler D, Yitzhaki S, Axelrod A, Zinman T, Shainberg A.

Bioelectromagnetics. 2012 Dec;33(8):634-40. doi: 10.1002/bem.21729. Epub 2012 Apr 24.

PMID:
22532275
30.

Reduced hepatic injury in Toll-like receptor 4-deficient mice following D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.

Ben Ari Z, Avlas O, Pappo O, Zilbermints V, Cheporko Y, Bachmetov L, Zemel R, Shainberg A, Sharon E, Grief F, Hochhauser E.

Cell Physiol Biochem. 2012;29(1-2):41-50. doi: 10.1159/000337585. Epub 2012 Mar 1.

31.

Conditioned medium from hypoxic cells protects cardiomyocytes against ischemia.

Chanyshev B, Shainberg A, Isak A, Chepurko Y, Porat E, Hochhauser E.

Mol Cell Biochem. 2012 Apr;363(1-2):167-78. doi: 10.1007/s11010-011-1169-7. Epub 2011 Dec 8.

PMID:
22160856
32.

Anti-ischemic effects of multivalent dendrimeric A₃ adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart.

Chanyshev B, Shainberg A, Isak A, Litinsky A, Chepurko Y, Tosh DK, Phan K, Gao ZG, Hochhauser E, Jacobson KA.

Pharmacol Res. 2012 Mar;65(3):338-46. doi: 10.1016/j.phrs.2011.11.013. Epub 2011 Dec 1.

33.

The plasma membrane is involved in the visible light-tissue interaction.

Lavi R, Ankri R, Sinyakov M, Eichler M, Friedmann H, Shainberg A, Breitbart H, Lubart R.

Photomed Laser Surg. 2012 Jan;30(1):14-9. doi: 10.1089/pho.2011.3083. Epub 2011 Oct 3.

PMID:
21967485
34.

UTP reduces infarct size and improves mice heart function after myocardial infarct via P2Y2 receptor.

Cohen R, Shainberg A, Hochhauser E, Cheporko Y, Tobar A, Birk E, Pinhas L, Leipziger J, Don J, Porat E.

Biochem Pharmacol. 2011 Nov 1;82(9):1126-33. doi: 10.1016/j.bcp.2011.07.094. Epub 2011 Aug 3.

PMID:
21839729
35.

Ca2+-induced PARP-1 activation and ANF expression are coupled events in cardiomyocytes.

Geistrikh I, Visochek L, Klein R, Miller L, Mittelman L, Shainberg A, Cohen-Armon M.

Biochem J. 2011 Sep 1;438(2):337-47. doi: 10.1042/BJ20101484.

PMID:
21635224
36.

Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.

El-Ani D, Stav H, Guetta V, Arad M, Shainberg A.

Life Sci. 2011 Jul 4;89(1-2):7-14. doi: 10.1016/j.lfs.2011.04.017. Epub 2011 May 12.

PMID:
21600903
37.

Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress.

Golan O, Issan Y, Isak A, Leipziger J, Robaye B, Shainberg A.

Biochem Pharmacol. 2011 May 15;81(10):1219-27. doi: 10.1016/j.bcp.2011.02.007. Epub 2011 Mar 3.

PMID:
21376706
38.

Toll-like receptor 4 stimulation initiates an inflammatory response that decreases cardiomyocyte contractility.

Avlas O, Fallach R, Shainberg A, Porat E, Hochhauser E.

Antioxid Redox Signal. 2011 Oct 1;15(7):1895-909. doi: 10.1089/ars.2010.3728. Epub 2011 Apr 21. Review.

PMID:
21126202
39.

Adenosine A(1) and A (3) receptor agonists reduce hypoxic injury through the involvement of P38 MAPK.

Leshem-Lev D, Hochhauser E, Chanyshev B, Isak A, Shainberg A.

Mol Cell Biochem. 2010 Dec;345(1-2):153-60. doi: 10.1007/s11010-010-0568-5. Epub 2010 Aug 22.

PMID:
20730620
40.

Detailed analysis of reactive oxygen species induced by visible light in various cell types.

Lavi R, Shainberg A, Shneyvays V, Hochauser E, Isaac A, Zinman T, Friedmann H, Lubart R.

Lasers Surg Med. 2010 Aug;42(6):473-80. doi: 10.1002/lsm.20919.

PMID:
20662023
41.

Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.

Katz G, Khoury A, Kurtzwald E, Hochhauser E, Porat E, Shainberg A, Seidman JG, Seidman CE, Lorber A, Eldar M, Arad M.

Heart Rhythm. 2010 Nov;7(11):1676-82. doi: 10.1016/j.hrthm.2010.07.004. Epub 2010 Jul 8.

42.

Multivalent dendrimeric and monomeric adenosine agonists attenuate cell death in HL-1 mouse cardiomyocytes expressing the A(3) receptor.

Keene AM, Balasubramanian R, Lloyd J, Shainberg A, Jacobson KA.

Biochem Pharmacol. 2010 Jul 15;80(2):188-96. doi: 10.1016/j.bcp.2010.03.020. Epub 2010 Mar 25.

43.

Cardiomyocyte Toll-like receptor 4 is involved in heart dysfunction following septic shock or myocardial ischemia.

Fallach R, Shainberg A, Avlas O, Fainblut M, Chepurko Y, Porat E, Hochhauser E.

J Mol Cell Cardiol. 2010 Jun;48(6):1236-44. doi: 10.1016/j.yjmcc.2010.02.020. Epub 2010 Mar 4.

PMID:
20211628
44.

Thyroid hormones and cardiac arrhythmias.

Tribulova N, Knezl V, Shainberg A, Seki S, Soukup T.

Vascul Pharmacol. 2010 Mar-Apr;52(3-4):102-12. doi: 10.1016/j.vph.2009.10.001. Epub 2009 Oct 20. Review.

PMID:
19850152
45.

Adenosine A3 receptor-mediated cardioprotection against doxorubicin-induced mitochondrial damage.

Emanuelov AK, Shainberg A, Chepurko Y, Kaplan D, Sagie A, Porat E, Arad M, Hochhauser E.

Biochem Pharmacol. 2010 Jan 15;79(2):180-7. doi: 10.1016/j.bcp.2009.08.010. Epub 2009 Aug 15.

PMID:
19686702
46.

Chapter 25: Phototherapy in peripheral nerve injury: effects on muscle preservation and nerve regeneration.

Rochkind S, Geuna S, Shainberg A.

Int Rev Neurobiol. 2009;87:445-64. doi: 10.1016/S0074-7742(09)87025-6. Review.

PMID:
19682654
47.

Uridine-5'-triphosphate protects against hepatic- ischemic/reperfusion injury in mice.

Ben-Ari Z, Pappo O, Yitzhaki S, Cheporko Y, Shainberg A, Zinman T, Ravid A, Zemel R, Bachmatov L, Kurtzwald E, Mor E, Hochhauser E.

Transplantation. 2009 Apr 27;87(8):1155-62. doi: 10.1097/TP.0b013e31819e3cdc.

PMID:
19384161
48.

Involvement of UTP in protection of cardiomyocytes from hypoxic stress.

Shainberg A, Yitzhaki S, Golan O, Jacobson KA, Hochhauser E.

Can J Physiol Pharmacol. 2009 Apr;87(4):287-99. doi: 10.1139/Y09-010.

49.

Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.

Klutz AM, Gao ZG, Lloyd J, Shainberg A, Jacobson KA.

J Nanobiotechnology. 2008 Oct 23;6:12. doi: 10.1186/1477-3155-6-12.

50.

Uridine-5'-triphosphate (UTP) maintains cardiac mitochondrial function following chemical and hypoxic stress.

Yitzhaki S, Hochhauser E, Porat E, Shainberg A.

J Mol Cell Cardiol. 2007 Nov;43(5):653-62. Epub 2007 Aug 7.

PMID:
17880998

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