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Items: 1 to 50 of 119

1.

High-throughput label-free flow cytometry based on matched-filter compressive imaging.

Ba C, Shain WJ, Bifano TG, Mertz J.

Biomed Opt Express. 2018 Nov 12;9(12):6145-6153. doi: 10.1364/BOE.9.006145. eCollection 2018 Dec 1.

2.

Axial localization with modulated-illumination extended-depth-of-field microscopy.

Shain WJ, Vickers NA, Li J, Han X, Bifano T, Mertz J.

Biomed Opt Express. 2018 Mar 21;9(4):1771-1782. doi: 10.1364/BOE.9.001771. eCollection 2018 Apr 1.

3.

Dual fluorescence-absorption deconvolution applied to extended-depth-of-field microscopy.

Shain WJ, Vickers NA, Negash A, Bifano T, Sentenac A, Mertz J.

Opt Lett. 2017 Oct 15;42(20):4183-4186. doi: 10.1364/OL.42.004183.

PMID:
29028043
4.

Reduced cell attachment to poly(2-hydroxyethyl methacrylate)-coated ventricular catheters in vitro.

Hanak BW, Hsieh CY, Donaldson W, Browd SR, Lau KKS, Shain W.

J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):1268-1279. doi: 10.1002/jbm.b.33915. Epub 2017 Jun 20.

5.

Extended depth-of-field microscopy with a high-speed deformable mirror.

Shain WJ, Vickers NA, Goldberg BB, Bifano T, Mertz J.

Opt Lett. 2017 Mar 1;42(5):995-998. doi: 10.1364/OL.42.000995.

PMID:
28248351
6.

Toward a better understanding of the cellular basis for cerebrospinal fluid shunt obstruction: report on the construction of a bank of explanted hydrocephalus devices.

Hanak BW, Ross EF, Harris CA, Browd SR, Shain W.

J Neurosurg Pediatr. 2016 Aug;18(2):213-23. doi: 10.3171/2016.2.PEDS15531. Epub 2016 Apr 1.

7.

Fabrication of three-dimensional hydrogel scaffolds for modeling shunt failure by tissue obstruction in hydrocephalus.

Harris C, Pearson K, Hadley K, Zhu S, Browd S, Hanak BW, Shain W.

Fluids Barriers CNS. 2015 Nov 14;12:26. doi: 10.1186/s12987-015-0023-9.

8.

Quantitative 3-D analysis of GFAP labeled astrocytes from fluorescence confocal images.

Kulkarni PM, Barton E, Savelonas M, Padmanabhan R, Lu Y, Trett K, Shain W, Leasure JL, Roysam B.

J Neurosci Methods. 2015 May 15;246:38-51. doi: 10.1016/j.jneumeth.2015.02.014. Epub 2015 Mar 5.

PMID:
25745860
9.

Population-scale three-dimensional reconstruction and quantitative profiling of microglia arbors.

Megjhani M, Rey-Villamizar N, Merouane A, Lu Y, Mukherjee A, Trett K, Chong P, Harris C, Shain W, Roysam B.

Bioinformatics. 2015 Jul 1;31(13):2190-8. doi: 10.1093/bioinformatics/btv109. Epub 2015 Feb 19.

10.

Quantitative arbor analytics: unsupervised harmonic co-clustering of populations of brain cell arbors based on L-measure.

Lu Y, Carin L, Coifman R, Shain W, Roysam B.

Neuroinformatics. 2015 Jan;13(1):47-63. doi: 10.1007/s12021-014-9237-2.

PMID:
25086878
11.

Large-scale automated image analysis for computational profiling of brain tissue surrounding implanted neuroprosthetic devices using Python.

Rey-Villamizar N, Somasundar V, Megjhani M, Xu Y, Lu Y, Padmanabhan R, Trett K, Shain W, Roysam B.

Front Neuroinform. 2014 Apr 29;8:39. doi: 10.3389/fninf.2014.00039. eCollection 2014.

12.

Whole animal perfusion fixation for rodents.

Gage GJ, Kipke DR, Shain W.

J Vis Exp. 2012 Jul 30;(65). pii: 3564. doi: 10.3791/3564.

13.

Knockdown of cortical transthyretin expression around implanted neural prosthetic devices using intraventricular siRNA injection in the brain.

Smith KL, Herron B, Dowell-Mesfin N, Wu H, Kim SJ, Shain W, Hynd MR.

J Neurosci Methods. 2012 Jan 30;203(2):398-406. doi: 10.1016/j.jneumeth.2011.09.023. Epub 2011 Sep 29.

PMID:
21978485
14.

The fate of ultrafast degrading polymeric implants in the brain.

Lewitus DY, Smith KL, Shain W, Bolikal D, Kohn J.

Biomaterials. 2011 Aug;32(24):5543-50. doi: 10.1016/j.biomaterials.2011.04.052. Epub 2011 May 24.

15.

Robust, globally consistent and fully automatic multi-image registration and montage synthesis for 3-D multi-channel images.

Tsai CL, Lister JP, Bjornsson CS, Smith K, Shain W, Barnes CA, Roysam B.

J Microsc. 2011 Aug;243(2):154-71. doi: 10.1111/j.1365-2818.2011.03489.x. Epub 2011 Mar 1.

16.

Ultrafast resorbing polymers for use as carriers for cortical neural probes.

Lewitus D, Smith KL, Shain W, Kohn J.

Acta Biomater. 2011 Jun;7(6):2483-91. doi: 10.1016/j.actbio.2011.02.027. Epub 2011 Feb 21.

PMID:
21345383
17.

Fabrication and optimization of alginate hydrogel constructs for use in 3D neural cell culture.

Frampton JP, Hynd MR, Shuler ML, Shain W.

Biomed Mater. 2011 Feb;6(1):015002. doi: 10.1088/1748-6041/6/1/015002. Epub 2011 Jan 5.

PMID:
21205998
18.

The effect of acoustically-induced cavitation on the permeance of a bullfrog urinary bladder.

Cancelos S, Moraga FJ, Lahey RT, Shain W, Parsons RH.

J Acoust Soc Am. 2010 Nov;128(5):2726-38. doi: 10.1121/1.3493442.

PMID:
21110568
19.

The national DBS brain tissue network pilot study: need for more tissue and more standardization.

Vedam-Mai V, Krock N, Ullman M, Foote KD, Shain W, Smith K, Yachnis AT, Steindler D, Reynolds B, Merritt S, Pagan F, Marjama-Lyons J, Hogarth P, Resnick AS, Zeilman P, Okun MS.

Cell Tissue Bank. 2011 Aug;12(3):219-31. doi: 10.1007/s10561-010-9189-1. Epub 2010 Jun 30.

PMID:
20589432
20.

Optical monitoring of neural networks evoked by focal electrical stimulation on microelectrode arrays using FM dyes.

Jun SB, Smith KL, Shain W, Dowell-Mesfin NM, Kim SJ, Hynd MR.

Med Biol Eng Comput. 2010 Sep;48(9):933-40. doi: 10.1007/s11517-010-0628-8. Epub 2010 May 21.

PMID:
20490941
21.

Effects of glial cells on electrode impedance recorded from neuralprosthetic devices in vitro.

Frampton JP, Hynd MR, Shuler ML, Shain W.

Ann Biomed Eng. 2010 Mar;38(3):1031-47.

PMID:
20336824
22.

Robust adaptive 3-D segmentation of vessel laminae from fluorescence confocal microscope images and parallel GPU implementation.

Narayanaswamy A, Dwarakapuram S, Bjornsson CS, Cutler BM, Shain W, Roysam B.

IEEE Trans Med Imaging. 2010 Mar;29(3):583-97. doi: 10.1109/TMI.2009.2022086.

23.

An in vitro system for modeling brain reactive responses and changes in neuroprosthetic device impedance.

Frampton JP, Hynd MR, Vargun A, Roysam B, Shain W.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:7155-8. doi: 10.1109/IEMBS.2009.5335352.

PMID:
19965268
24.

The central role of neuroinformatics in the National Academy of Engineering's grandest challenge: reverse engineer the brain.

Roysam B, Shain W, Ascoli GA.

Neuroinformatics. 2009 Spring;7(1):1-5. doi: 10.1007/s12021-008-9043-9. Epub 2009 Jan 13. No abstract available.

25.

Biomedical Technologies for in vitro Screening and Controlled Delivery of Neuroactive Compounds.

Frampton JP, Shuler ML, Shain W, Hynd MR.

Cent Nerv Syst Agents Med Chem. 2008;8(3):203-219.

26.

Release of nerve growth factor from HEMA hydrogel-coated substrates and its effect on the differentiation of neural cells.

Jhaveri SJ, Hynd MR, Dowell-Mesfin N, Turner JN, Shain W, Ober CK.

Biomacromolecules. 2009 Jan 12;10(1):174-83. doi: 10.1021/bm801101e.

PMID:
19061335
27.

Advanced neurotechnologies for chronic neural interfaces: new horizons and clinical opportunities.

Kipke DR, Shain W, Buzsáki G, Fetz E, Henderson JM, Hetke JF, Schalk G.

J Neurosci. 2008 Nov 12;28(46):11830-8. doi: 10.1523/JNEUROSCI.3879-08.2008. Review. No abstract available.

28.

Constant pressure fluid infusion into rat neocortex from implantable microfluidic devices.

Retterer ST, Smith KL, Bjornsson CS, Turner JN, Isaacson MS, Shain W.

J Neural Eng. 2008 Dec;5(4):385-91. doi: 10.1088/1741-2560/5/4/003. Epub 2008 Sep 30.

PMID:
18827310
29.

Cryopreservation of transfected primary dorsal root ganglia neurons.

Seggio AM, Ellison KS, Hynd MR, Shain W, Thompson DM.

J Neurosci Methods. 2008 Aug 15;173(1):67-73. doi: 10.1016/j.jneumeth.2008.05.017. Epub 2008 May 28.

PMID:
18639343
30.

Modulation of cultured neural networks using neurotrophin release from hydrogel-coated microelectrode arrays.

Jun SB, Hynd MR, Dowell-Mesfin NM, Al-Kofahi Y, Roysam B, Shain W, Kim SJ.

J Neural Eng. 2008 Jun;5(2):203-13. doi: 10.1088/1741-2560/5/2/011. Epub 2008 May 13.

31.

Associative image analysis: a method for automated quantification of 3D multi-parameter images of brain tissue.

Bjornsson CS, Lin G, Al-Kofahi Y, Narayanaswamy A, Smith KL, Shain W, Roysam B.

J Neurosci Methods. 2008 May 15;170(1):165-78. doi: 10.1016/j.jneumeth.2007.12.024. Epub 2008 Jan 17.

32.

Improved detection of branching points in algorithms for automated neuron tracing from 3D confocal images.

Al-Kofahi Y, Dowell-Mesfin N, Pace C, Shain W, Turner JN, Roysam B.

Cytometry A. 2008 Jan;73(1):36-43.

33.

Complex impedance spectroscopy for monitoring tissue responses to inserted neural implants.

Williams JC, Hippensteel JA, Dilgen J, Shain W, Kipke DR.

J Neural Eng. 2007 Dec;4(4):410-23. Epub 2007 Nov 27.

34.

Three-dimensional hydrogel cultures for modeling changes in tissue impedance around microfabricated neural probes.

Frampton JP, Hynd MR, Williams JC, Shuler ML, Shain W.

J Neural Eng. 2007 Dec;4(4):399-409. Epub 2007 Nov 27.

PMID:
18057507
35.

Applications of hydrogels for neural cell engineering.

Hynd MR, Turner JN, Shain W.

J Biomater Sci Polym Ed. 2007;18(10):1223-44. Review.

PMID:
17939883
36.

Electrical stimulation-induced cell clustering in cultured neural networks.

Jun SB, Hynd MR, Smith KL, Song JK, Turner JN, Shain W, Kim SJ.

Med Biol Eng Comput. 2007 Nov;45(11):1015-21. Epub 2007 Aug 8.

PMID:
17684784
37.

A multi-model approach to simultaneous segmentation and classification of heterogeneous populations of cell nuclei in 3D confocal microscope images.

Lin G, Chawla MK, Olson K, Barnes CA, Guzowski JF, Bjornsson C, Shain W, Roysam B.

Cytometry A. 2007 Sep;71(9):724-36.

38.

Directed cell growth on protein-functionalized hydrogel surfaces.

Hynd MR, Frampton JP, Dowell-Mesfin N, Turner JN, Shain W.

J Neurosci Methods. 2007 May 15;162(1-2):255-63. Epub 2007 Feb 4.

39.

Synaptic connectivity of a low density patterned neuronal network produced on the poly-L-lysine stamped microelectrode array.

Beom Jun S, Hynd M, Dowell-Mesfin N, Smith K, Turner J, Shain W, June Kim S.

Conf Proc IEEE Eng Med Biol Soc. 2005;7:7604-7.

PMID:
17282041
40.

Functionalized hydrogel surfaces for the patterning of multiple biomolecules.

Hynd MR, Frampton JP, Burnham MR, Martin DL, Dowell-Mesfin NM, Turner JN, Shain W.

J Biomed Mater Res A. 2007 May;81(2):347-54.

PMID:
17120223
41.

Low-density neuronal networks cultured using patterned poly-l-lysine on microelectrode arrays.

Jun SB, Hynd MR, Dowell-Mesfin N, Smith KL, Turner JN, Shain W, Kim SJ.

J Neurosci Methods. 2007 Mar 15;160(2):317-26. Epub 2006 Oct 17.

42.

Effects of insertion conditions on tissue strain and vascular damage during neuroprosthetic device insertion.

Bjornsson CS, Oh SJ, Al-Kofahi YA, Lim YJ, Smith KL, Turner JN, De S, Roysam B, Shain W, Kim SJ.

J Neural Eng. 2006 Sep;3(3):196-207. Epub 2006 Jun 21.

PMID:
16921203
43.

BCI Meeting 2005--workshop on signals and recording methods.

Wolpaw JR, Loeb GE, Allison BZ, Donchin E, do Nascimento OF, Heetderks WJ, Nijboer F, Shain WG, Turner JN.

IEEE Trans Neural Syst Rehabil Eng. 2006 Jun;14(2):138-41.

PMID:
16792279
44.

Dexamethasone treatment reduces astroglia responses to inserted neuroprosthetic devices in rat neocortex.

Spataro L, Dilgen J, Retterer S, Spence AJ, Isaacson M, Turner JN, Shain W.

Exp Neurol. 2005 Aug;194(2):289-300.

PMID:
16022859
45.

Automated image analysis methods for 3-D quantification of the neurovascular unit from multichannel confocal microscope images.

Lin G, Bjornsson CS, Smith KL, Abdul-Karim MA, Turner JN, Shain W, Roysam B.

Cytometry A. 2005 Jul;66(1):9-23.

46.

Topographically modified surfaces affect orientation and growth of hippocampal neurons.

Dowell-Mesfin NM, Abdul-Karim MA, Turner AM, Schanz S, Craighead HG, Roysam B, Turner JN, Shain W.

J Neural Eng. 2004 Jun;1(2):78-90. Epub 2004 Jun 14.

PMID:
15876626
47.

An endothelial and astrocyte co-culture model of the blood-brain barrier utilizing an ultra-thin, nanofabricated silicon nitride membrane.

Ma SH, Lepak LA, Hussain RJ, Shain W, Shuler ML.

Lab Chip. 2005 Jan;5(1):74-85. Epub 2004 Oct 14.

PMID:
15616743
48.

Model neural prostheses with integrated microfluidics: a potential intervention strategy for controlling reactive cell and tissue responses.

Retterer ST, Smith KL, Bjornsson CS, Neeves KB, Spence AJ, Turner JN, Shain W, Isaacson MS.

IEEE Trans Biomed Eng. 2004 Nov;51(11):2063-73.

PMID:
15536908
49.

Extracellular recordings from patterned neuronal networks using planar microelectrode arrays.

James CD, Spence AJ, Dowell-Mesfin NM, Hussain RJ, Smith KL, Craighead HG, Isaacson MS, Shain W, Turner JN.

IEEE Trans Biomed Eng. 2004 Sep;51(9):1640-8.

PMID:
15376512
50.

Median-based robust algorithms for tracing neurons from noisy confocal microscope images.

Al-Kofahi KA, Can A, Lasek S, Szarowski DH, Dowell-Mesfin N, Shain W, Turner JN, Roysam B.

IEEE Trans Inf Technol Biomed. 2003 Dec;7(4):302-17.

PMID:
15000357

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