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Items: 29

1.

Potential fluoride toxicity from oral medicaments: A review.

Ullah R, Zafar MS, Shahani N.

Iran J Basic Med Sci. 2017 Aug;20(8):841-848. doi: 10.22038/IJBMS.2017.9104. Review.

2.

Forebrain depletion of Rheb GTPase elicits spatial memory deficits in mice.

Shahani N, Huang WC, Varnum M, Page DT, Subramaniam S.

Neurobiol Aging. 2017 Feb;50:134-143. doi: 10.1016/j.neurobiolaging.2016.11.006. Epub 2016 Nov 21.

3.

RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.

Shahani N, Swarnkar S, Giovinazzo V, Morgenweck J, Bohn LM, Scharager-Tapia C, Pascal B, Martinez-Acedo P, Khare K, Subramaniam S.

Sci Signal. 2016 Nov 15;9(454):ra111.

4.

Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53.

Kim SH, Shahani N, Bae BI, Sbodio JI, Chung Y, Nakaso K, Paul BD, Sawa A.

Hum Mol Genet. 2016 Jun 15;25(12):2514-2524. Epub 2016 May 19.

5.

Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.

Swarnkar S, Chen Y, Pryor WM, Shahani N, Page DT, Subramaniam S.

Neurobiol Dis. 2015 Oct;82:66-77. doi: 10.1016/j.nbd.2015.05.011. Epub 2015 Jun 3.

PMID:
26048156
6.

Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke.

Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, Shahani N, Itakura M, Ono Y, Azuma YT, Inui T, Kamiya A, Sawa A, Takeuchi T.

J Biol Chem. 2015 Jun 5;290(23):14493-503. doi: 10.1074/jbc.M114.635607. Epub 2015 Apr 16.

7.

Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade.

Tyagi R, Shahani N, Gorgen L, Ferretti M, Pryor W, Chen PY, Swarnkar S, Worley PF, Karbstein K, Snyder SH, Subramaniam S.

Cell Rep. 2015 Feb 10;10(5):684-693. doi: 10.1016/j.celrep.2015.01.014. Epub 2015 Feb 7.

8.

Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade.

Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A.

J Biol Chem. 2015 Jan 2;290(1):56-64. doi: 10.1074/jbc.M114.596205. Epub 2014 Nov 12.

9.

Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.

Pryor WM, Biagioli M, Shahani N, Swarnkar S, Huang WC, Page DT, MacDonald ME, Subramaniam S.

Sci Signal. 2014 Oct 28;7(349):ra103. doi: 10.1126/scisignal.2005633.

PMID:
25351248
10.

DISC1 regulates trafficking and processing of APP and Aβ generation.

Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A.

Mol Psychiatry. 2015 Jul;20(7):874-9. doi: 10.1038/mp.2014.100. Epub 2014 Sep 16.

11.

Mir-592 regulates the induction and cell death-promoting activity of p75NTR in neuronal ischemic injury.

Irmady K, Jackman KA, Padow VA, Shahani N, Martin LA, Cerchietti L, Unsicker K, Iadecola C, Hempstead BL.

J Neurosci. 2014 Feb 26;34(9):3419-28. doi: 10.1523/JNEUROSCI.1982-13.2014.

12.

Rheb GTPase regulates β-secretase levels and amyloid β generation.

Shahani N, Pryor W, Swarnkar S, Kholodilov N, Thinakaran G, Burke RE, Subramaniam S.

J Biol Chem. 2014 Feb 28;289(9):5799-808. doi: 10.1074/jbc.M113.532713. Epub 2013 Dec 24.

13.

Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.

Mealer RG, Murray AJ, Shahani N, Subramaniam S, Snyder SH.

J Biol Chem. 2014 Feb 7;289(6):3547-54. doi: 10.1074/jbc.M113.536912. Epub 2013 Dec 9.

14.

Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness.

Johnson AW, Jaaro-Peled H, Shahani N, Sedlak TW, Zoubovsky S, Burruss D, Emiliani F, Sawa A, Gallagher M.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12462-7. doi: 10.1073/pnas.1307925110. Epub 2013 Jul 9.

15.

Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.

Subramaniam S, Napolitano F, Mealer RG, Kim S, Errico F, Barrow R, Shahani N, Tyagi R, Snyder SH, Usiello A.

Nat Neurosci. 2011 Dec 18;15(2):191-3. doi: 10.1038/nn.2994.

16.

Protein S-nitrosylation: role for nitric oxide signaling in neuronal death.

Shahani N, Sawa A.

Biochim Biophys Acta. 2012 Jun;1820(6):736-42. doi: 10.1016/j.bbagen.2011.07.010. Epub 2011 Jul 23. Review.

17.

Down regulation of trophic factors in neonatal rat spinal cord after administration of cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients.

Deepa P, Shahani N, Alladi PA, Vijayalakshmi K, Sathyaprabha TN, Nalini A, Ravi V, Raju TR.

J Neural Transm (Vienna). 2011 Apr;118(4):531-8. doi: 10.1007/s00702-010-0520-6. Epub 2010 Nov 11.

PMID:
21069391
18.

Nitric oxide signaling and nitrosative stress in neurons: role for S-nitrosylation.

Shahani N, Sawa A.

Antioxid Redox Signal. 2011 Apr 15;14(8):1493-504. doi: 10.1089/ars.2010.3580. Epub 2011 Feb 17. Review.

PMID:
20812870
19.

The diverse functions of GAPDH: views from different subcellular compartments.

Tristan C, Shahani N, Sedlak TW, Sawa A.

Cell Signal. 2011 Feb;23(2):317-23. doi: 10.1016/j.cellsig.2010.08.003. Epub 2010 Aug 19. Review.

20.

Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.

Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A.

Nat Cell Biol. 2008 Jul;10(7):866-73. doi: 10.1038/ncb1747. Epub 2008 Jun 15.

22.

Purification of MINUS: A negative regulator of microtubule nucleation in a variety of organisms.

Shahani N, Subramaniam S, Brandt R.

Int J Biol Macromol. 2006 Aug 15;39(1-3):15-22. Epub 2006 Jan 18.

PMID:
16420961
23.
24.

Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.

Brandt R, Hundelt M, Shahani N.

Biochim Biophys Acta. 2005 Jan 3;1739(2-3):331-54. Review.

25.

(-)-Deprenyl alleviates the degenerative changes induced in the neonatal rat spinal cord by CSF from amyotrophic lateral sclerosis patients.

Shahani N, Gourie-Devi M, Nalini A, Rammohan P, Shobha K, Harsha HN, Raju TR.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Sep;5(3):172-9.

PMID:
15512906
26.

Functions and malfunctions of the tau proteins.

Shahani N, Brandt R.

Cell Mol Life Sci. 2002 Oct;59(10):1668-80. Review.

PMID:
12475178
27.
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