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Items: 1 to 50 of 191

1.

A model to predict liver disease progression in heavy drinkers: Clinical utility for today and deep learning for the future.

Ahn JC, Shah VH.

Clin Gastroenterol Hepatol. 2020 Feb 13. pii: S1542-3565(20)30176-2. doi: 10.1016/j.cgh.2020.02.012. [Epub ahead of print] No abstract available.

PMID:
32062043
2.

Fecal microbiome distinguishes alcohol consumption from alcoholic hepatitis but does not discriminate disease severity.

Smirnova E, Puri P, Muthiah MD, Daitya K, Brown R, Chalasani N, Liangpunsakul S, Shah VH, Gelow K, Siddiqui MS, Boyett S, Mirshahi F, Sikaroodi M, Gillevet P, Sanyal AJ.

Hepatology. 2020 Feb 14. doi: 10.1002/hep.31178. [Epub ahead of print]

PMID:
32056227
3.

Multiparametric Magnetic Resonance Elastography Improves the Detection of NASH Regression Following Bariatric Surgery.

Allen AM, Shah VH, Therneau TM, Venkatesh SK, Mounajjed T, Larson JJ, Mara KC, Kellogg TA, Kendrick ML, McKenzie TJ, Greiner SM, Li J, Glaser KJ, Wells ML, Gunneson TJ, Ehman RL, Yin M.

Hepatol Commun. 2019 Nov 5;4(2):185-192. doi: 10.1002/hep4.1446. eCollection 2020 Feb.

4.

Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis.

Mindikoglu AL, Coarfa C, Opekun AR, Shah VH, Arab JP, Lazaridis KN, Putluri N, Ambati CR, Robertson MJ, Devaraj S, Jalal PK, Rana A, Goss JA, Dowling TC, Weir MR, Seliger SL, Raufman JP, Bernard DW, Vierling JM.

Future Sci OA. 2019 Dec 17;6(2):FSO441. doi: 10.2144/fsoa-2019-0124.

5.

The transcriptome of hepatic fibrosis revealed by single cell RNA sequencing.

Jophlin LL, Cao S, Shah VH.

Hepatology. 2020 Feb 3. doi: 10.1002/hep.31155. [Epub ahead of print]

PMID:
32017148
6.

Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis.

Atkinson SR, Hamesch K, Spivak I, Guldiken N, Cabezas J, Argemi J, Theurl I, Zoller H, Cao S, Mathurin P, Shah VH, Trautwein C, Bataller R, Thursz MR, Strnad P.

Am J Gastroenterol. 2020 Jan 24. doi: 10.14309/ajg.0000000000000492. [Epub ahead of print]

PMID:
31985531
7.

A single nucleotide polymorphism of PLIN2 is associated with nonalcoholic steatohepatitis and causes phenotypic changes in hepatocyte lipid droplets: A pilot study.

Faulkner CS, White CM, Shah VH, Jophlin LL.

Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jan 23:158637. doi: 10.1016/j.bbalip.2020.158637. [Epub ahead of print] No abstract available.

PMID:
31981756
8.

Small but mighty: Platelets in NASH and other chronic liver diseases.

Hilscher MB, Shah VH.

Hepatology. 2020 Jan 5. doi: 10.1002/hep.31101. [Epub ahead of print]

PMID:
31903616
9.

Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: Current concepts and perspectives.

Arab JP, Arrese M, Shah VH.

Hepatol Res. 2019 Dec 15. doi: 10.1111/hepr.13473. [Epub ahead of print] Review.

PMID:
31840358
10.

Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice.

Xiang X, Feng D, Hwang S, Ren T, Wang X, Trojnar E, Matyas C, Mo R, Shang D, He Y, Seo W, Shah VH, Pacher P, Xie Q, Gao B.

J Hepatol. 2019 Nov 29. pii: S0168-8278(19)30700-7. doi: 10.1016/j.jhep.2019.11.013. [Epub ahead of print]

PMID:
31786256
11.

An Open Label, Dose Escalation Study To Assess The Safety And Efficacy Of IL-22 Agonist F-652 In Patients With Alcoholic Hepatitis.

Arab JP, Sehrawat TS, Simonetto DA, Verma VK, Feng D, Tang T, Dreyer K, Yan X, Daley WL, Sanyal A, Chalasani N, Radaeva S, Yang L, Vargas H, Ibacache M, Gao B, Gores GJ, Malhi H, Kamath PS, Shah VH.

Hepatology. 2019 Nov 27. doi: 10.1002/hep.31046. [Epub ahead of print]

PMID:
31774566
12.

Meeting Report: The Dallas Consensus Conference on Liver Transplantation for Alcohol Associated Hepatitis.

Asrani SK, Trotter J, Lake J, Ahmed A, Bonagura A, Cameron A, DiMartini A, Gonzalez S, Im G, Martin P, Mathurin P, Mellinger J, Rice JP, Shah VH, Terrault N, Wall A, Winder S, Klintmalm G.

Liver Transpl. 2020 Jan;26(1):127-140. doi: 10.1002/lt.25681.

PMID:
31743578
13.

Neutrophil Extracellular Traps and Liver Disease.

Hilscher MB, Shah VH.

Semin Liver Dis. 2019 Nov 14. doi: 10.1055/s-0039-3399562. [Epub ahead of print]

PMID:
31726473
14.

Author Correction: Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs.

Shaheen MF, Joo DJ, Ross JJ, Anderson BD, Chen HS, Huebert RC, Li Y, Amiot B, Young A, Zlochiver V, Nelson E, Mounajjed T, Dietz AB, Michalak G, Steiner BG, Davidow DS, Paradise CR, van Wijnen AJ, Shah VH, Liu M, Nyberg SL.

Nat Biomed Eng. 2019 Nov 5. doi: 10.1038/s41551-019-0483-3. [Epub ahead of print]

PMID:
31690827
15.

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.

Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ.

Sci Transl Med. 2019 Oct 30;11(516). pii: eaau6296. doi: 10.1126/scitranslmed.aau6296.

PMID:
31666402
16.

Increasing Burden of Acute-On-Chronic Liver Failure Among Alcohol-Associated Liver Disease in the Young Population in the United States.

Singal AK, Arora S, Wong RJ, Satapathy SK, Shah VH, Kuo YF, Kamath PS.

Am J Gastroenterol. 2020 Jan;115(1):88-95. doi: 10.14309/ajg.0000000000000411.

PMID:
31651447
17.

Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs.

Shaheen MF, Joo DJ, Ross JJ, Anderson BD, Chen HS, Huebert RC, Li Y, Amiot B, Young A, Zlochiver V, Nelson E, Mounajjed T, Dietz AB, Michalak G, Steiner BG, Davidow DS, Paradise CR, van Wijnen AJ, Shah VH, Liu M, Nyberg SL.

Nat Biomed Eng. 2019 Oct 14. doi: 10.1038/s41551-019-0460-x. [Epub ahead of print] Erratum in: Nat Biomed Eng. 2019 Nov 5;:.

PMID:
31611679
18.

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R.

Nat Commun. 2019 Jul 16;10(1):3126. doi: 10.1038/s41467-019-11004-3.

19.

Prevalence and Predictors of Third-Generation Cephalosporin Resistance in the Empirical Treatment of Spontaneous Bacterial Peritonitis.

Sunjaya DB, Lennon RJ, Shah VH, Kamath PS, Simonetto DA.

Mayo Clin Proc. 2019 Aug;94(8):1499-1508. doi: 10.1016/j.mayocp.2018.12.036. Epub 2019 Jul 11.

PMID:
31303428
20.

Assessing Surgical Risk in Idiopathic Portal Hypertension: Some Answers, an Extrapolation, and More Questions.

Simonetto DA, Kamath PS, Shah VH.

Hepatology. 2019 Sep;70(3):767-770. doi: 10.1002/hep.30847. Epub 2019 Aug 19. No abstract available.

PMID:
31298742
21.

New Prospects for Medical Management of Acute Alcoholic Hepatitis.

Liu M, Shah VH.

Clin Liver Dis (Hoboken). 2019 May 31;13(5):131-135. doi: 10.1002/cld.792. eCollection 2019 May. Review. No abstract available.

22.

Alcohol Abstinence Does Not Fully Reverse Abnormalities of Mucosal-Associated Invariant T Cells in the Blood of Patients With Alcoholic Hepatitis.

Li W, Lin EL, Liangpunsakul S, Lan J, Chalasani S, Rane S, Puri P, Kamath PS, Sanyal AJ, Shah VH, Radaeva S, Crabb DW, Chalasani N, Yu Q.

Clin Transl Gastroenterol. 2019 Jun;10(6):e00052. doi: 10.14309/ctg.0000000000000052.

23.

Blueberry Muffin Baby with Cytomegalovirus Hepatitis.

Shah VH, Rambhia KD, Mukhi JI, Singh RP.

Indian Dermatol Online J. 2019 May-Jun;10(3):327-329. doi: 10.4103/idoj.IDOJ_291_18. No abstract available.

24.

How to Use Emotional Intelligence as a Career Catalyst- the X-Factor of Success for Trainees and Faculty in Gastroenterology and Hepatology.

Shah VH, Shah PP.

Gastroenterology. 2019 Aug;157(2):289-292. doi: 10.1053/j.gastro.2019.05.009. Epub 2019 May 11. No abstract available.

PMID:
31085197
25.

Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis.

Jalan-Sakrikar N, De Assuncao TM, Shi G, Aseem SO, Chi C, Shah VH, Huebert RC.

Hepatology. 2019 Nov;70(5):1674-1689. doi: 10.1002/hep.30706. Epub 2019 Jun 22.

PMID:
31070797
26.

Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells.

Wang L, Feng Y, Xie X, Wu H, Su XN, Qi J, Xin W, Gao L, Zhang Y, Shah VH, Zhu Q.

EBioMedicine. 2019 May;43:525-536. doi: 10.1016/j.ebiom.2019.04.050. Epub 2019 May 3.

27.

Alcohol-related liver disease: Clinical practice guidelines by the Latin American Association for the Study of the Liver (ALEH).

Arab JP, Roblero JP, Altamirano J, Bessone F, Chaves Araujo R, Higuera-De la Tijera F, Restrepo JC, Torre A, Urzua A, Simonetto DA, Abraldes JG, Méndez-Sánchez N, Contreras F, Lucey MR, Shah VH, Cortez-Pinto H, Bataller R.

Ann Hepatol. 2019 May - Jun;18(3):518-535. doi: 10.1016/j.aohep.2019.04.005. Epub 2019 Apr 18. Review.

28.

Alcohol Rehabilitation Within 30 Days of Hospital Discharge Is Associated With Reduced Readmission, Relapse, and Death in Patients With Alcoholic Hepatitis.

Peeraphatdit TB, Kamath PS, Karpyak VM, Davis B, Desai V, Liangpunsakul S, Sanyal A, Chalasani N, Shah VH, Simonetto DA.

Clin Gastroenterol Hepatol. 2020 Feb;18(2):477-485.e5. doi: 10.1016/j.cgh.2019.04.048. Epub 2019 Apr 28.

PMID:
31042580
29.

p300 Acetyltransferase Is a Cytoplasm-to-Nucleus Shuttle for SMAD2/3 and TAZ Nuclear Transport in Transforming Growth Factor β-Stimulated Hepatic Stellate Cells.

Wang Y, Tu K, Liu D, Guo L, Chen Y, Li Q, Maiers JL, Liu Z, Shah VH, Dou C, Tschumperlin D, Voneschen L, Yang R, Kang N.

Hepatology. 2019 Oct;70(4):1409-1423. doi: 10.1002/hep.30668. Epub 2019 May 23.

30.

Extracellular vesicles, the liquid biopsy of the future.

Eguchi A, Kostallari E, Feldstein AE, Shah VH.

J Hepatol. 2019 Jun;70(6):1292-1294. doi: 10.1016/j.jhep.2019.01.030. Epub 2019 Apr 12. No abstract available.

PMID:
30982591
31.

Incidence and Risk Factors Associated With 30-Day Readmission for Alcoholic Hepatitis.

Garg SK, Sarvepalli S, Singh D, Obaitan I, Peeraphatdit T, Jophlin L, Asrani SK, Shah VH, Leise MD.

J Clin Gastroenterol. 2019 Nov/Dec;53(10):759-764. doi: 10.1097/MCG.0000000000001202.

PMID:
30950924
32.

Pericytes in the Liver.

Kostallari E, Shah VH.

Adv Exp Med Biol. 2019;1122:153-167. doi: 10.1007/978-3-030-11093-2_9. Review.

PMID:
30937868
33.

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension.

Hilscher MB, Sehrawat T, Arab JP, Zeng Z, Gao J, Liu M, Kostallari E, Gao Y, Simonetto DA, Yaqoob U, Cao S, Revzin A, Beyder A, Wang RA, Kamath PS, Kubes P, Shah VH.

Gastroenterology. 2019 Jul;157(1):193-209.e9. doi: 10.1053/j.gastro.2019.03.013. Epub 2019 Mar 11.

PMID:
30872106
34.

Current trials and novel therapeutic targets for alcoholic hepatitis.

Singal AK, Shah VH.

J Hepatol. 2019 Feb;70(2):305-313. doi: 10.1016/j.jhep.2018.10.026. Review.

PMID:
30658731
35.

Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study.

Thursz M, Kamath PS, Mathurin P, Szabo G, Shah VH.

J Hepatol. 2019 Mar;70(3):521-530. doi: 10.1016/j.jhep.2018.10.041. Epub 2019 Jan 15. Review.

PMID:
30658117
36.

Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study.

Szabo G, Kamath PS, Shah VH, Thursz M, Mathurin P; EASL-AASLD Joint Meeting.

Hepatology. 2019 May;69(5):2271-2283. doi: 10.1002/hep.30369. Epub 2019 Jan 15. Review.

PMID:
30645002
37.

Response to Forrest et al.

Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH.

Am J Gastroenterol. 2019 Jan;114(1):176. doi: 10.14309/ajg.0000000000000073. No abstract available.

PMID:
30633036
38.

Transforming growth factor β (TGFβ) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation.

Liu Z, Li C, Kang N, Malhi H, Shah VH, Maiers JL.

J Biol Chem. 2019 Mar 1;294(9):3137-3151. doi: 10.1074/jbc.RA118.005761. Epub 2019 Jan 4.

PMID:
30610118
39.

The Role of Three-Dimensional Magnetic Resonance Elastography in the Diagnosis of Nonalcoholic Steatohepatitis in Obese Patients Undergoing Bariatric Surgery.

Allen AM, Shah VH, Therneau TM, Venkatesh SK, Mounajjed T, Larson JJ, Mara KC, Schulte PJ, Kellogg TA, Kendrick ML, McKenzie TJ, Greiner SM, Li J, Glaser KJ, Wells ML, Chen J, Ehman RL, Yin M.

Hepatology. 2020 Feb;71(2):510-521. doi: 10.1002/hep.30483. Epub 2019 Mar 15.

PMID:
30582669
40.

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis.

Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH.

Cell Mol Gastroenterol Hepatol. 2019;7(1):197-209. doi: 10.1016/j.jcmgh.2018.09.005. Epub 2018 Sep 15.

41.

Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension.

Abraldes JG, Trebicka J, Chalasani N, D'Amico G, Rockey DC, Shah VH, Bosch J, Garcia-Tsao G.

Hepatology. 2019 Mar;69(3):1287-1299. doi: 10.1002/hep.30314. Epub 2019 Feb 9.

42.

A Validated Score Predicts Acute Kidney Injury and Survival in Patients With Alcoholic Hepatitis.

Sujan R, Cruz-Lemini M, Altamirano J, Simonetto DA, Maiwall R, Axley P, Richardson T, Desai V, Cabezas J, Vargas V, Kamath PS, Shah VH, Sarin SK, Bataller R, Singal AK.

Liver Transpl. 2018 Dec;24(12):1655-1664. doi: 10.1002/lt.25328.

43.

Comparison of Therapies for Primary Prevention of Esophageal Variceal Bleeding: A Systematic Review and Network Meta-analysis.

Sharma M, Singh S, Desai V, Shah VH, Kamath PS, Murad MH, Simonetto DA.

Hepatology. 2019 Apr;69(4):1657-1675. doi: 10.1002/hep.30220. Epub 2019 Feb 20.

PMID:
30125369
44.

Posttraumatic Stress Disorder in Patients with Heavy Alcohol Consumption and Alcoholic Hepatitis.

Samala N, Lourens SG, Shah VH, Kamath PS, Sanyal AJ, Crabb DW, Tang Q, Radaeva S, Liangpunsakul S, Chalasani N.

Alcohol Clin Exp Res. 2018 Oct;42(10):1933-1938. doi: 10.1111/acer.13862. Epub 2018 Aug 26.

45.

Too Stiff, Too Late . . . Timing Is Everything in Antiangiogenic Treatment of Liver Fibrosis.

Greuter T, Shah VH.

Hepatology. 2019 Jan;69(1):449-451. doi: 10.1002/hep.30124. Epub 2018 Dec 18. No abstract available.

46.

Psoriasis: implication to disease and therapeutic strategies, with an emphasis on drug delivery approaches.

Todke P, Shah VH.

Int J Dermatol. 2018 Nov;57(11):1387-1402. doi: 10.1111/ijd.14047. Epub 2018 Jun 19. Review.

PMID:
29923192
47.

Exploring new treatment paradigms for alcoholic hepatitis by extrapolating from NASH and cholestasis.

Peeraphatdit TB, Simonetto DA, Shah VH.

J Hepatol. 2018 Aug;69(2):275-277. doi: 10.1016/j.jhep.2018.05.012. Epub 2018 May 21. No abstract available.

48.

Grand Rounds: Alcoholic Hepatitis.

Singal AK, Louvet A, Shah VH, Kamath PS.

J Hepatol. 2018 Aug;69(2):534-543. doi: 10.1016/j.jhep.2018.05.001. Epub 2018 Jun 13. Review.

49.

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.

Dou C, Liu Z, Tu K, Zhang H, Chen C, Yaqoob U, Wang Y, Wen J, van Deursen J, Sicard D, Tschumperlin D, Zou H, Huang WC, Urrutia R, Shah VH, Kang N.

Gastroenterology. 2018 Jun;154(8):2209-2221.e14. doi: 10.1053/j.gastro.2018.02.015. Epub 2018 Feb 15.

50.

Incidence and cost analysis of hospital admission and 30-day readmission among patients with cirrhosis.

Chirapongsathorn S, Krittanawong C, Enders FT, Pendegraft R, Mara KC, Borah BJ, Visscher SL, Loftus CG, Shah VH, Talwalkar JA, Kamath PS.

Hepatol Commun. 2018 Jan 18;2(2):188-198. doi: 10.1002/hep4.1137. eCollection 2018 Feb.

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