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The Molecular Medicine Investigation Unit: Linking Patient Care and Scientific Inquiry in Physician-Scientist Training.

Berger A, Matloubian M, Shah NP, Wachter RM, DeRisi JL, Anderson M.

J Grad Med Educ. 2020 Feb;12(1):92-97. doi: 10.4300/JGME-D-19-00507.1.


Case series, contemporary review and imaging guided diagnostic and management approach of congenital pericardial defects.

Khayata M, Alkharabsheh S, Shah NP, Verma BR, Gentry JL, Summers M, Xu B, Asher C, Klein AL.

Open Heart. 2020 Jan 8;7(1):e001103. doi: 10.1136/openhrt-2019-001103. eCollection 2020.


Enterococcus hirae WEHI01 isolated from a healthy Chinese infant ameliorates the symptoms of type 2 diabetes by elevating the abundance of Lactobacillales in rats.

Wei M, Gu E, Luo J, Zhang Z, Xu D, Tao X, Shah NP, Wei H.

J Dairy Sci. 2020 Feb 11. pii: S0022-0302(20)30102-8. doi: 10.3168/jds.2019-17185. [Epub ahead of print]


Familial hypercholesterolemia: Detect, treat, and ask about family.

Shah NP, Ahmed HM, Wilson Tang WH.

Cleve Clin J Med. 2020 Feb;87(2):109-120. doi: 10.3949/ccjm.87a.19021.


Proteomic analysis reveals potential factors associated with enhanced EPS production in Streptococcus thermophilus ASCC 1275.

Padmanabhan A, Tong Y, Wu Q, Lo C, Shah NP.

Sci Rep. 2020 Jan 21;10(1):807. doi: 10.1038/s41598-020-57665-9.


The Role of Lipoprotein (a) as a Marker of Residual Risk in Patients With Diabetes and Established Cardiovascular Disease on Optimal Medical Therapy: Post Hoc Analysis of ACCELERATE.

Shah NP, Wang Q, Wolski KE, Cho L, McErlean E, Ruotolo G, Weerakkody G, Riesmeyer JS, Nicholls SJ, Lincoff AM, Nissen SE, Menon V.

Diabetes Care. 2020 Feb;43(2):e22-e24. doi: 10.2337/dc19-1117. Epub 2019 Dec 5. No abstract available.


Dasatinib discontinuation in patients with chronic-phase chronic myeloid leukemia and stable deep molecular response: the DASFREE study.

Shah NP, García-Gutiérrez V, Jiménez-Velasco A, Larson S, Saussele S, Rea D, Mahon FX, Levy MY, Gómez-Casares MT, Pane F, Nicolini FE, Mauro MJ, Sy O, Martin-Regueira P, Lipton JH.

Leuk Lymphoma. 2020 Mar;61(3):650-659. doi: 10.1080/10428194.2019.1675879. Epub 2019 Oct 24.


Detection of Pan drug resistance OXA-48 producing Providencia in an ICU patient for the first time in Nepal.

Sah R, Khadka S, Shrestha GS, Acharya S, Aryal D, Shrestha P, Kattel HP, Shah NP, Pokhrel BM, Singh YP, Rijal B, Erdem H.

Antimicrob Resist Infect Control. 2019 Oct 15;8:155. doi: 10.1186/s13756-019-0608-1. eCollection 2019.


Functional Genomic Analyses of Exopolysaccharide-Producing Streptococcus thermophilus ASCC 1275 in Response to Milk Fermentation Conditions.

Wu Q, Chu H, Padmanabhan A, Shah NP.

Front Microbiol. 2019 Aug 23;10:1975. doi: 10.3389/fmicb.2019.01975. eCollection 2019.


Comparative evaluation of the shear bond strength of adhesive and self-adhesive resin luting agents to three commercially available composite core build-up materials: An in vitro study.

Terni PM, Nadgere JB, Ram SM, Shah NP, Mahadevan J.

J Indian Prosthodont Soc. 2019 Jul-Sep;19(3):255-260. doi: 10.4103/jips.jips_84_19.


Purpura fulminans manifesting with Staphylococcus aureus endocarditis: a case report.

Kumar A, Shah NP, Menon V, Nissen SE.

Eur Heart J Case Rep. 2019 Jun 1;3(2). pii: ytz077. doi: 10.1093/ehjcr/ytz077.


ATP-Competitive Inhibitors Midostaurin and Avapritinib Have Distinct Resistance Profiles in Exon 17-Mutant KIT.

Apsel Winger B, Cortopassi WA, Garrido Ruiz D, Ding L, Jang K, Leyte-Vidal A, Zhang N, Esteve-Puig R, Jacobson MP, Shah NP.

Cancer Res. 2019 Aug 15;79(16):4283-4292. doi: 10.1158/0008-5472.CAN-18-3139. Epub 2019 Jul 3.


Unusual Physiological Properties of Smooth Monostratified Ganglion Cell Types in Primate Retina.

Rhoades CE, Shah NP, Manookin MB, Brackbill N, Kling A, Goetz G, Sher A, Litke AM, Chichilnisky EJ.

Neuron. 2019 Aug 21;103(4):658-672.e6. doi: 10.1016/j.neuron.2019.05.036. Epub 2019 Jun 18.


Effects of Lactic Acid Bacteria-Fermented Soymilk on Isoflavone Metabolites and Short-Chain Fatty Acids Excretion and Their Modulating Effects on Gut Microbiota.

Dai S, Pan M, El-Nezami HS, Wan JMF, Wang MF, Habimana O, Lee JCY, Louie JCY, Shah NP.

J Food Sci. 2019 Jul;84(7):1854-1863. doi: 10.1111/1750-3841.14661. Epub 2019 Jun 17.


Recreating first digit with silicone prosthesis.

Gaikwad AM, Ram SM, Nadgere JB, Shah NP.

Natl J Maxillofac Surg. 2019 Jan-Jun;10(1):105-108. doi: 10.4103/njms.NJMS_59_18.


Pericardial Cysts: a Contemporary Comprehensive Review.

Khayata M, Alkharabsheh S, Shah NP, Klein AL.

Curr Cardiol Rep. 2019 May 30;21(7):64. doi: 10.1007/s11886-019-1153-5. Review.


NCCN Guidelines Updates: Discontinuing TKI Therapy in the Treatment of Chronic Myeloid Leukemia.

Shah NP.

J Natl Compr Canc Netw. 2019 May 1;17(5.5):611-613. doi: 10.6004/jnccn.2019.5013.


Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.

McMahon CM, Ferng T, Canaani J, Wang ES, Morrissette JJD, Eastburn DJ, Pellegrino M, Durruthy-Durruthy R, Watt CD, Asthana S, Lasater EA, DeFilippis R, Peretz CAC, McGary LHF, Deihimi S, Logan AC, Luger SM, Shah NP, Carroll M, Smith CC, Perl AE.

Cancer Discov. 2019 Aug;9(8):1050-1063. doi: 10.1158/2159-8290.CD-18-1453. Epub 2019 May 14.


Sulfonation of Lactobacillus plantarum WLPL04 exopolysaccharide amplifies its antioxidant activities in vitro and in a Caco-2 cell model.

Liu Z, Dong L, Jia K, Zhan H, Zhang Z, Shah NP, Tao X, Wei H.

J Dairy Sci. 2019 Jul;102(7):5922-5932. doi: 10.3168/jds.2018-15831. Epub 2019 Apr 25.


Exercise Is Good for the Heart But Not for the Inflamed Pericardium?

Shah NP, Verma BR, Ala CK, Khayata M, Phelan D, Imazio M, Klein AL.

JACC Cardiovasc Imaging. 2019 Sep;12(9):1880-1881. doi: 10.1016/j.jcmg.2019.01.022. Epub 2019 Mar 13. No abstract available.


Effects of high-density lipoprotein targeting treatments on cardiovascular outcomes: A systematic review and meta-analysis.

Riaz H, Khan SU, Rahman H, Shah NP, Kaluski E, Lincoff AM, Nissen SE.

Eur J Prev Cardiol. 2019 Mar;26(5):533-543. doi: 10.1177/2047487318816495. Epub 2018 Dec 6.


Correction: Hypertension guidelines.

Aleyadeh W, Hutt-Centeno E, Ahmed HM, Shah NP.

Cleve Clin J Med. 2019 Mar;86(3):210.


Hypertension guidelines: Treat patients, not numbers.

Aleyadeh W, Hutt-Centeno E, Ahmed HM, Shah NP.

Cleve Clin J Med. 2019 Jan;86(1):47-56. doi: 10.3949/ccjm.86a.18027. Review. Erratum in: Cleve Clin J Med. 2019 Mar;86(3):210.


Predictors of cardiorespiratory fitness improvement in phase II cardiac rehabilitation.

Abu-Haniyeh A, Shah NP, Wu Y, Cho L, Ahmed HM.

Clin Cardiol. 2018 Dec;41(12):1563-1569. doi: 10.1002/clc.23101. Epub 2018 Nov 26.


Chronic Myeloid Leukemia, Version 1.2019, NCCN Clinical Practice Guidelines in Oncology.

Radich JP, Deininger M, Abboud CN, Altman JK, Berman E, Bhatia R, Bhatnagar B, Curtin P, DeAngelo DJ, Gotlib J, Hobbs G, Jagasia M, Kantarjian HM, Maness L, Metheny L, Moore JO, Pallera A, Pancari P, Patnaik M, Purev E, Rose MG, Shah NP, Smith BD, Snyder DS, Sweet KL, Talpaz M, Thompson J, Yang DT, Gregory KM, Sundar H.

J Natl Compr Canc Netw. 2018 Sep;16(9):1108-1135. doi: 10.6004/jnccn.2018.0071.


Transcriptomic Insights Into the Growth Phase- and Sugar-Associated Changes in the Exopolysaccharide Production of a High EPS-Producing Streptococcus thermophilus ASCC 1275.

Padmanabhan A, Tong Y, Wu Q, Zhang J, Shah NP.

Front Microbiol. 2018 Aug 20;9:1919. doi: 10.3389/fmicb.2018.01919. eCollection 2018.


Familial Chylomicronemia Syndrome: Clinical Characteristics and Long-Term Cardiovascular Outcomes.

Shah NP, Cho L, Ahmed HM.

J Am Coll Cardiol. 2018 Sep 4;72(10):1177-1179. doi: 10.1016/j.jacc.2018.06.042. No abstract available.


Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia.

Hughes TP, Laneuville P, Rousselot P, Snyder DS, Rea D, Shah NP, Paar D, Abruzzese E, Hochhaus A, Lipton JH, Cortes JE.

Haematologica. 2019 Jan;104(1):93-101. doi: 10.3324/haematol.2018.188987. Epub 2018 Aug 9.


Human case of Fasciola gigantica-like infection, review of human fascioliasis reports in Nepal, and epidemiological analysis within the South Central Asia.

Sah R, Khadka S, Lakhey PJ, Pradhan S, Shah NP, Singh YP, Mas-Coma S.

Acta Parasitol. 2018 Sep 25;63(3):435-443. doi: 10.1515/ap-2018-0053. Review.


Effects of Lactobacillus rhamnosus GG and Escherichia coli Nissle 1917 Cell-Free Supernatants on Modulation of Mucin and Cytokine Secretion on Human Intestinal Epithelial HT29-MTX Cells.

Wan ML, Chen Z, Shah NP, El-Nezami H.

J Food Sci. 2018 Jul;83(7):1999-2007. doi: 10.1111/1750-3841.14168. Epub 2018 Jun 4.


Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial.

Cortes J, Perl AE, Döhner H, Kantarjian H, Martinelli G, Kovacsovics T, Rousselot P, Steffen B, Dombret H, Estey E, Strickland S, Altman JK, Baldus CD, Burnett A, Krämer A, Russell N, Shah NP, Smith CC, Wang ES, Ifrah N, Gammon G, Trone D, Lazzaretto D, Levis M.

Lancet Oncol. 2018 Jul;19(7):889-903. doi: 10.1016/S1470-2045(18)30240-7. Epub 2018 May 31.


Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia.

Atallah E, Schiffer CA, Weinfurt KP, Zhang MJ, Radich JP, Oehler VG, Pinilla-Ibarz J, Deininger MWN, Lin L, Larson RA, Mauro MJ, Moore JO, Ritchie EK, Shah NP, Silver RT, Wadleigh M, Cortes J, Thompson J, Guhl J, Horowitz MM, Flynn KE.

BMC Cancer. 2018 Apr 2;18(1):359. doi: 10.1186/s12885-018-4273-1.


Physicochemical and textural properties of mozzarella cheese made with konjac glucomannan as a fat replacer.

Dai S, Jiang F, Corke H, Shah NP.

Food Res Int. 2018 May;107:691-699. doi: 10.1016/j.foodres.2018.02.069. Epub 2018 Feb 28.


Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.

Cortes JE, Kim DW, Pinilla-Ibarz J, le Coutre PD, Paquette R, Chuah C, Nicolini FE, Apperley JF, Khoury HJ, Talpaz M, DeAngelo DJ, Abruzzese E, Rea D, Baccarani M, Müller MC, Gambacorti-Passerini C, Lustgarten S, Rivera VM, Haluska FG, Guilhot F, Deininger MW, Hochhaus A, Hughes TP, Shah NP, Kantarjian HM.

Blood. 2018 Jul 26;132(4):393-404. doi: 10.1182/blood-2016-09-739086. Epub 2018 Mar 22.


Bifurcation of the inferior dental nerve canal: an anatomical study.

Shah NP, Murtadha L, Brown J.

Br J Oral Maxillofac Surg. 2018 May;56(4):267-271. doi: 10.1016/j.bjoms.2018.01.016. Epub 2018 Mar 7.


Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT.

Bharate JB, McConnell N, Naresh G, Zhang L, Lakkaniga NR, Ding L, Shah NP, Frett B, Li HY.

Sci Rep. 2018 Feb 27;8(1):3722. doi: 10.1038/s41598-018-21839-3.


Cardiac Rehabilitation: Current Review of the Literature and Its Role in Patients with Heart Failure.

Shah NP, AbuHaniyeh A, Ahmed H.

Curr Treat Options Cardiovasc Med. 2018 Feb 24;20(2):12. doi: 10.1007/s11936-018-0611-5. Review.


Front-Line Treatment Options for Chronic-Phase Chronic Myeloid Leukemia.

Shah NP.

J Clin Oncol. 2018 Jan 20;36(3):220-224. doi: 10.1200/JCO.2017.75.4663. Epub 2017 Dec 5.


Restoration of GABA production machinery in Lactobacillus brevis by accessible carbohydrates, anaerobiosis and early acidification.

Wu Q, Shah NP.

Food Microbiol. 2018 Feb;69:151-158. doi: 10.1016/ Epub 2017 Aug 16.


Human fascioliasis by Fasciola hepatica: the first case report in Nepal.

Sah R, Khadka S, Khadka M, Gurubacharya D, Sherchand JB, Parajuli K, Shah NP, Kattel HP, Pokharel BM, Rijal B.

BMC Res Notes. 2017 Sep 5;10(1):439. doi: 10.1186/s13104-017-2761-z.


Effect of Type of Protein-Based Microcapsules and Storage at Various Ambient Temperatures on the Survival and Heat Tolerance of Spray Dried Lactobacillus acidophilus.

Dianawati D, Lim SF, Ooi YBH, Shah NP.

J Food Sci. 2017 Sep;82(9):2134-2141. doi: 10.1111/1750-3841.13820. Epub 2017 Aug 26.


Health-promoting benefits of low-fat akawi cheese made by exopolysaccharide-producing probiotic Lactobacillus plantarum isolated from camel milk.

Al-Dhaheri AS, Al-Hemeiri R, Kizhakkayil J, Al-Nabulsi A, Abushelaibi A, Shah NP, Ayyash M.

J Dairy Sci. 2017 Oct;100(10):7771-7779. doi: 10.3168/jds.2017-12761. Epub 2017 Jul 26.


Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells.

Metts J, Bradley HL, Wang Z, Shah NP, Kapur R, Arbiser JL, Bunting KD.

Sci Rep. 2017 Jun 30;7(1):4447. doi: 10.1038/s41598-017-04796-1.


Influence of commercial culture composition and cow milk to soy milk ratio on the biochemical, microbiological, and sensory characteristics of a probiotic fermented composite drink.

Mohammadi R, Yousefi M, Sarlak Z, Shah NP, Mortazavian AM, Sadeghi E, Khajavi MZ.

Food Sci Biotechnol. 2017 May 29;26(3):749-757. doi: 10.1007/s10068-017-0097-z. eCollection 2017.


Evaluation of cardiovascular ischemic event rates in dasatinib-treated patients using standardized incidence ratios.

Saglio G, le Coutre P, Cortes J, Mayer J, Rowlings P, Mahon FX, Kroog G, Gooden K, Subar M, Shah NP.

Ann Hematol. 2017 Aug;96(8):1303-1313. doi: 10.1007/s00277-017-3012-z. Epub 2017 May 22.


Beyond ONJ - A review of the potential uses of bisphosphonates in dentistry.

Shah NP, Nayee S, Pazianas M, Sproat C.

Br Dent J. 2017 May 12;222(9):727-730. doi: 10.1038/sj.bdj.2017.412. Review.


Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysis.

Smith CC, Paguirigan A, Jeschke GR, Lin KC, Massi E, Tarver T, Chin CS, Asthana S, Olshen A, Travers KJ, Wang S, Levis MJ, Perl AE, Radich JP, Shah NP.

Blood. 2017 Jul 6;130(1):48-58. doi: 10.1182/blood-2016-04-711820. Epub 2017 May 10.


Common Distribution of gad Operon in Lactobacillus brevis and its GadA Contributes to Efficient GABA Synthesis toward Cytosolic Near-Neutral pH.

Wu Q, Tun HM, Law YS, Khafipour E, Shah NP.

Front Microbiol. 2017 Feb 14;8:206. doi: 10.3389/fmicb.2017.00206. eCollection 2017.

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