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Items: 1 to 50 of 172

1.

Medical students' perceptions of their learning environment during clinical years at Chitwan Medical College in Nepal.

Shah DK, Piryani S, Piryani RM, Islam MN, Jha RK, Deo GP.

Adv Med Educ Pract. 2019 Jul 24;10:555-562. doi: 10.2147/AMEP.S203377. eCollection 2019.

2.

Effect of Size on Solid Tumor Disposition of Protein Therapeutics.

Li Z, Li Y, Chang HP, Chang HY, Guo L, Shah DK.

Drug Metab Dispos. 2019 Aug 6. pii: dmd.119.087809. doi: 10.1124/dmd.119.087809. [Epub ahead of print]

3.

Development and validation of an LC-MS/MS method for tyrphostin A9.

Meyer LF, Shah DK.

J Pharm Anal. 2019 Jun;9(3):163-169. doi: 10.1016/j.jpha.2019.03.003. Epub 2019 Mar 8.

4.

Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART®.

Betts A, Haddish-Berhane N, Shah DK, van der Graaf PH, Barletta F, King L, Clark T, Kamperschroer C, Root A, Hooper A, Chen X.

AAPS J. 2019 Jun 4;21(4):73. doi: 10.1208/s12248-019-0348-4.

PMID:
31165304
5.

A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART®.

Betts A, Haddish-Berhane N, Shah DK, van der Graaf PH, Barletta F, King L, Clark T, Kamperschroer C, Root A, Hooper A, Chen X.

AAPS J. 2019 May 22;21(4):66. doi: 10.1208/s12248-019-0332-z. Erratum in: AAPS J. 2019 Jun 4;21(4):73.

6.

A translational platform PBPK model for antibody disposition in the brain.

Chang HY, Wu S, Meno-Tetang G, Shah DK.

J Pharmacokinet Pharmacodyn. 2019 Aug;46(4):319-338. doi: 10.1007/s10928-019-09641-8. Epub 2019 May 21.

PMID:
31115858
7.

Two-pore physiologically based pharmacokinetic model with de novo derived parameters for predicting plasma PK of different size protein therapeutics.

Li Z, Shah DK.

J Pharmacokinet Pharmacodyn. 2019 Jun;46(3):305-318. doi: 10.1007/s10928-019-09639-2. Epub 2019 Apr 26.

PMID:
31028591
8.

A Cell-Level Systems PK-PD Model to Characterize In Vivo Efficacy of ADCs.

Singh AP, Guo L, Verma A, Wong GG, Shah DK.

Pharmaceutics. 2019 Feb 25;11(2). pii: E98. doi: 10.3390/pharmaceutics11020098.

9.

A "Dual" Cell-Level Systems PK-PD Model to Characterize the Bystander Effect of ADC.

Singh AP, Shah DK.

J Pharm Sci. 2019 Jul;108(7):2465-2475. doi: 10.1016/j.xphs.2019.01.034. Epub 2019 Feb 18.

PMID:
30790581
10.

Estimation of Solid Tumor Doubling Times from Progression-Free Survival Plots Using a Novel Statistical Approach.

Kay K, Dolcy K, Bies R, Shah DK.

AAPS J. 2019 Feb 8;21(2):27. doi: 10.1208/s12248-019-0302-5.

PMID:
30737615
11.

Validation of Multicolor Imaging of Diabetic Retinopathy Lesions Vis a Vis Conventional Color Fundus Photographs.

Roy R, Saurabh K, Thomas NR, Chowdhury M, Shah DK.

Ophthalmic Surg Lasers Imaging Retina. 2019 Jan 1;50(1):8-15. doi: 10.3928/23258160-20181212-02.

PMID:
30640390
12.

Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice.

Khot A, Matsueda S, Thomas VA, Koya RC, Shah DK.

J Pharmacol Exp Ther. 2019 Mar;368(3):503-513. doi: 10.1124/jpet.118.252858. Epub 2019 Jan 8.

PMID:
30622170
13.

Pharmacokinetics of protein and peptide conjugates.

Bumbaca B, Li Z, Shah DK.

Drug Metab Pharmacokinet. 2019 Feb;34(1):42-54. doi: 10.1016/j.dmpk.2018.11.001. Epub 2018 Nov 22. Review.

PMID:
30573392
14.

Engineered pH-dependent recycling antibodies enhance elimination of Staphylococcal enterotoxin B superantigen in mice.

Kroetsch A, Qiao C, Heavey M, Guo L, Shah DK, Park S.

MAbs. 2019 Feb/Mar;11(2):411-421. doi: 10.1080/19420862.2018.1545510. Epub 2018 Dec 11.

PMID:
30526311
15.

Target-Mediated Drug Disposition Model for Bispecific Antibodies: Properties, Approximation, and Optimal Dosing Strategy.

Schropp J, Khot A, Shah DK, Koch G.

CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):177-187. doi: 10.1002/psp4.12369. Epub 2019 Jan 8.

16.

Characterisation of neonatal seizures and their treatment using continuous EEG monitoring: a multicentre experience.

Rennie JM, de Vries LS, Blennow M, Foran A, Shah DK, Livingstone V, van Huffelen AC, Mathieson SR, Pavlidis E, Weeke LC, Toet MC, Finder M, Pinnamaneni RM, Murray DM, Ryan AC, Marnane WP, Boylan GB.

Arch Dis Child Fetal Neonatal Ed. 2019 Sep;104(5):F493-F501. doi: 10.1136/archdischild-2018-315624. Epub 2018 Nov 24.

PMID:
30472660
17.

Blood pressure intervention levels in preterm infants: pilot randomised trial.

Pereira SS, Sinha AK, Morris JK, Wertheim DF, Shah DK, Kempley ST.

Arch Dis Child Fetal Neonatal Ed. 2019 May;104(3):F298-F305. doi: 10.1136/archdischild-2017-314159. Epub 2018 Jul 26.

PMID:
30049724
18.

Risk for and consequences of endometriosis: A critical epidemiologic review.

Shafrir AL, Farland LV, Shah DK, Harris HR, Kvaskoff M, Zondervan K, Missmer SA.

Best Pract Res Clin Obstet Gynaecol. 2018 Aug;51:1-15. doi: 10.1016/j.bpobgyn.2018.06.001. Epub 2018 Jul 3. Review.

PMID:
30017581
19.

Association of Patient Race With Surgical Practice and Perioperative Morbidity After Myomectomy.

Stentz NC, Cooney LG, Sammel MD, Shah DK.

Obstet Gynecol. 2018 Aug;132(2):291-297. doi: 10.1097/AOG.0000000000002738.

PMID:
29995738
20.

Antibody pharmacokinetics in rat brain determined using microdialysis.

Chang HY, Morrow K, Bonacquisti E, Zhang W, Shah DK.

MAbs. 2018 Aug/Sep;10(6):843-853. doi: 10.1080/19420862.2018.1473910. Epub 2018 Aug 6.

21.

Big data approach to evaluation of birth defects and assisted reproductive technology: the Chinese linkage cohort.

Sammel MD, Stentz N, Shah DK.

Fertil Steril. 2018 May;109(5):791-792. doi: 10.1016/j.fertnstert.2018.02.115. No abstract available.

PMID:
29778375
22.

Attitude and perception of undergraduate medical students toward the problem-based learning in Chitwan Medical College, Nepal.

Yadav RL, Piryani RM, Deo GP, Shah DK, Yadav LK, Islam MN.

Adv Med Educ Pract. 2018 May 4;9:317-322. doi: 10.2147/AMEP.S160814. eCollection 2018.

23.

Physiologically-based pharmacokinetic model of vaginally administered dapivirine ring and film formulations.

Kay K, Shah DK, Rohan L, Bies R.

Br J Clin Pharmacol. 2018 Sep;84(9):1950-1969. doi: 10.1111/bcp.13625. Epub 2018 Jun 19.

24.

Early echocardiography does not predict subsequent treatment of symptomatic patent ductus arteriosus in extremely preterm infants.

Pereira SS, Kempley ST, Shah DK, Morris JK, Sinha AK.

Acta Paediatr. 2018 Nov;107(11):1909-1916. doi: 10.1111/apa.14361. Epub 2018 May 11.

PMID:
29663524
25.

Raised Plasma Neurofilament Light Protein Levels Are Associated with Abnormal MRI Outcomes in Newborns Undergoing Therapeutic Hypothermia.

Shah DK, Ponnusamy V, Evanson J, Kapellou O, Ekitzidou G, Gupta N, Clarke P, Michael-Titus AT, Yip PK.

Front Neurol. 2018 Mar 5;9:86. doi: 10.3389/fneur.2018.00086. eCollection 2018.

26.

Investigation of EEG Activity Compared with Mean Arterial Blood Pressure in Extremely Preterm Infants.

Pereira SS, Kempley ST, Wertheim DF, Sinha AK, Morris JK, Shah DK.

Front Neurol. 2018 Feb 26;9:87. doi: 10.3389/fneur.2018.00087. eCollection 2018.

27.

Establishing in vitro-in vivo correlation for antibody drug conjugate efficacy: a PK/PD modeling approach.

Shah DK, Loganzo F, Haddish-Berhane N, Musto S, Wald HS, Barletta F, Lucas J, Clark T, Hansel S, Betts A.

J Pharmacokinet Pharmacodyn. 2018 Apr;45(2):339-349. doi: 10.1007/s10928-018-9577-x. Epub 2018 Feb 8.

PMID:
29423862
28.

Quantitative systems toxicology.

Bloomingdale P, Housand C, Apgar JF, Millard BL, Mager DE, Burke JM, Shah DK.

Curr Opin Toxicol. 2017 Jun;4:79-87. doi: 10.1016/j.cotox.2017.07.003. Epub 2017 Aug 2.

29.

Difference between mean gestational sac diameter and crown-rump length as a marker of first-trimester pregnancy loss after in vitro fertilization.

Kapfhamer JD, Palaniappan S, Summers K, Kassel K, Mancuso AC, Ryan GL, Shah DK.

Fertil Steril. 2018 Jan;109(1):130-136. doi: 10.1016/j.fertnstert.2017.09.031. Epub 2017 Nov 23.

30.

The Epidemiology of Brachial Plexus Birth Palsy in the United States: Declining Incidence and Evolving Risk Factors.

DeFrancesco CJ, Shah DK, Rogers BH, Shah AS.

J Pediatr Orthop. 2019 Feb;39(2):e134-e140. doi: 10.1097/BPO.0000000000001089.

PMID:
29016426
31.

Encapsulation of Human Islets Using a Biomimetic Self-Assembled Nanomatrix Gel for Protection against Cellular Inflammatory Responses.

Hwang PTJ, Shah DK, Garcia JA, Alexander GC, Lim DJ, Cui W, Cooper DK, Shalev A, Kin T, Kim JA, Jun HW.

ACS Biomater Sci Eng. 2017 Sep 11;3(9):2110-2119. doi: 10.1021/acsbiomaterials.7b00261. Epub 2017 Jul 11.

32.

Measurement and Mathematical Characterization of Cell-Level Pharmacokinetics of Antibody-Drug Conjugates: A Case Study with Trastuzumab-vc-MMAE.

Singh AP, Shah DK.

Drug Metab Dispos. 2017 Nov;45(11):1120-1132. doi: 10.1124/dmd.117.076414. Epub 2017 Aug 18.

33.

Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1.

Khot A, Tibbitts J, Rock D, Shah DK.

AAPS J. 2017 Nov;19(6):1715-1734. doi: 10.1208/s12248-017-0131-3. Epub 2017 Aug 14.

34.

Fertility preservation training for obstetrics and gynecology fellows: a highly desired but non-standardized experience.

Miller EJN, Cookingham LM, Woodruff TK, Ryan GL, Summers KM, Kondapalli LA, Shah DK.

Fertil Res Pract. 2017 Jul 4;3:9. doi: 10.1186/s40738-017-0036-y. eCollection 2017.

35.

Influence of Molecular size on the clearance of antibody fragments.

Li Z, Krippendorff BF, Shah DK.

Pharm Res. 2017 Oct;34(10):2131-2141. doi: 10.1007/s11095-017-2219-y. Epub 2017 Jul 5.

36.

Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine.

Yadav PK, Yadav RL, Sharma D, Shah DK, Thakur D, Limbu N, Islam MN.

J Clin Diagn Res. 2017 Mar;11(3):CC05-CC09. doi: 10.7860/JCDR/2017/22814.9399. Epub 2017 Mar 1.

37.

Changes in Myomectomy Practice After the U.S. Food and Drug Administration Safety Communication on Power Morcellation.

Stentz NC, Cooney LG, Sammel M, Shah DK.

Obstet Gynecol. 2017 Jun;129(6):1007-1013. doi: 10.1097/AOG.0000000000002035.

38.

Hypoxic-Ischaemic Encephalopathy and the Blood-Brain Barrier in Neonates.

Lee WLA, Michael-Titus AT, Shah DK.

Dev Neurosci. 2017;39(1-4):49-58. doi: 10.1159/000467392. Epub 2017 Apr 22. Review.

PMID:
28434009
39.
40.

Vibration upshot of operating mechanical sewing machine: an insight into common peroneal nerve conduction study.

Yadav PK, Yadav RL, Sharma D, Shah DK, Sapkota NK, Thakur D, Limbu N, Islam MN.

Ann Occup Environ Med. 2017 Mar 24;29:8. doi: 10.1186/s40557-017-0164-1. eCollection 2017.

41.

Progress and challenges of the bioartificial pancreas.

Hwang PT, Shah DK, Garcia JA, Bae CY, Lim DJ, Huiszoon RC, Alexander GC, Jun HW.

Nano Converg. 2016;3(1):28. doi: 10.1186/s40580-016-0088-4. Epub 2016 Nov 1. Review.

42.

Somatic neural alterations in non-diabetic obesity: a cross-sectional study.

Yadav RL, Sharma D, Yadav PK, Shah DK, Agrawal K, Khadka R, Islam MN.

BMC Obes. 2016 Nov 22;3:50. eCollection 2016.

43.

Association Between Body Mass Index, Uterine Size, and Operative Morbidity in Women Undergoing Minimally Invasive Hysterectomy.

Shah DK, Van Voorhis BJ, Vitonis AF, Missmer SA.

J Minim Invasive Gynecol. 2016 Nov - Dec;23(7):1113-1122. doi: 10.1016/j.jmig.2016.08.003. Epub 2016 Aug 11.

PMID:
27523922
44.

Perioperative mortality is the Achilles heel for cardiac transplantation in adults with congenital heart disease: Evidence from analysis of the UNOS registry.

Shah DK, Deo SV, Althouse AD, Teuteberg JJ, Park SJ, Kormos RL, Burkhart HM, Morell VO.

J Card Surg. 2016 Dec;31(12):755-764. doi: 10.1111/jocs.12857. Epub 2016 Oct 5.

PMID:
27709686
45.

Quantitative characterization of in vitro bystander effect of antibody-drug conjugates.

Singh AP, Sharma S, Shah DK.

J Pharmacokinet Pharmacodyn. 2016 Dec;43(6):567-582. Epub 2016 Sep 26.

46.

Facebook use and its effects on the life of health science students in a private medical college of Nepal.

Jha RK, Shah DK, Basnet S, Paudel KR, Sah P, Sah AK, Adhikari K.

BMC Res Notes. 2016 Aug 2;9:378. doi: 10.1186/s13104-016-2186-0.

47.

Cerebral function monitoring on a general paediatric ward: feasibility and potential.

Kalra V, Shaw SS, Dixon S, Shah DK, Clarke P.

Eur J Pediatr. 2016 Aug;175(8):1059-64. doi: 10.1007/s00431-016-2737-3. Epub 2016 Jun 6.

PMID:
27271341
48.

Automated electroencephalographic discontinuity in cooled newborns predicts cerebral MRI and neurodevelopmental outcome.

Dunne JM, Wertheim D, Clarke P, Kapellou O, Chisholm P, Boardman JP, Shah DK.

Arch Dis Child Fetal Neonatal Ed. 2017 Jan;102(1):F58-F64. doi: 10.1136/archdischild-2015-309697. Epub 2016 Apr 21.

PMID:
27103657
49.

Evolution of Antibody-Drug Conjugate Tumor Disposition Model to Predict Preclinical Tumor Pharmacokinetics of Trastuzumab-Emtansine (T-DM1).

Singh AP, Maass KF, Betts AM, Wittrup KD, Kulkarni C, King LE, Khot A, Shah DK.

AAPS J. 2016 Jul;18(4):861-75. doi: 10.1208/s12248-016-9904-3. Epub 2016 Mar 30.

50.

Learning approach among health sciences students in a medical college in Nepal: a cross-sectional study.

Shah DK, Yadav RL, Sharma D, Yadav PK, Sapkota NK, Jha RK, Islam MN.

Adv Med Educ Pract. 2016 Mar 4;7:137-43. doi: 10.2147/AMEP.S100968. eCollection 2016.

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