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Items: 1 to 50 of 149

1.

Genes and Pathways Promoting Long-Term Liver Repopulation by Ex Vivo hYAP-ERT2 Transduced Hepatocytes and Treatment of Jaundice in Gunn Rats.

Peterson EA, Polgar Z, Devakanmalai GS, Li Y, Jaber FL, Zhang W, Wang X, Iqbal NJ, Murray JW, Roy-Chowdhury N, Quispe-Tintaya W, Maslov AY, Tchaikovskaya TL, Sharma Y, Rogler LE, Gupta S, Zhu L, Roy-Chowdhury J, Shafritz DA.

Hepatol Commun. 2018 Nov 20;3(1):129-146. doi: 10.1002/hep4.1278. eCollection 2019 Jan.

2.

Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location.

Yovchev M, Jaber FL, Lu Z, Patel S, Locker J, Rogler LE, Murray JW, Sudol M, Dabeva MD, Zhu L, Shafritz DA.

Sci Rep. 2016 Jan 14;6:19275. doi: 10.1038/srep19275.

3.

Repopulation of the fibrotic/cirrhotic rat liver by transplanted hepatic stem/progenitor cells and mature hepatocytes.

Yovchev MI, Xue Y, Shafritz DA, Locker J, Oertel M.

Hepatology. 2014 Jan;59(1):284-95. doi: 10.1002/hep.26615. Epub 2013 Nov 18.

4.

Activin A, p15INK4b signaling, and cell competition promote stem/progenitor cell repopulation of livers in aging rats.

Menthena A, Koehler CI, Sandhu JS, Yovchev MI, Hurston E, Shafritz DA, Oertel M.

Gastroenterology. 2011 Mar;140(3):1009-20. doi: 10.1053/j.gastro.2010.12.003. Epub 2010 Dec 11.

5.

To TWEAK, or not to TWEAK: that is the question.

Shafritz DA.

Hepatology. 2010 Jul;52(1):13-5. doi: 10.1002/hep.23750. No abstract available.

PMID:
20578125
6.

Model systems and experimental conditions that lead to effective repopulation of the liver by transplanted cells.

Shafritz DA, Oertel M.

Int J Biochem Cell Biol. 2011 Feb;43(2):198-213. doi: 10.1016/j.biocel.2010.01.013. Epub 2010 Jan 18. Review.

7.

Purification of fetal liver stem/progenitor cells containing all the repopulation potential for normal adult rat liver.

Oertel M, Menthena A, Chen YQ, Teisner B, Jensen CH, Shafritz DA.

Gastroenterology. 2008 Mar;134(3):823-32. doi: 10.1053/j.gastro.2008.01.007. Epub 2008 Jan 10.

PMID:
18262526
8.

Stem cells, cell transplantation and liver repopulation.

Oertel M, Shafritz DA.

Biochim Biophys Acta. 2008 Feb;1782(2):61-74. doi: 10.1016/j.bbadis.2007.12.004. Epub 2007 Dec 23. Review.

9.

A human hepatocyte factory.

Shafritz DA.

Nat Biotechnol. 2007 Aug;25(8):871-2. No abstract available.

PMID:
17687361
10.
11.

Inactivation of p27Kip1 promotes chemical mouse liver tumorigenesis in the resistant strain C57BL/6J.

Sun D, Ren H, Oertel M, Sellers RS, Shafritz DA, Zhu L.

Mol Carcinog. 2008 Jan;47(1):47-55.

PMID:
17620307
12.

New cell surface markers for murine fetal hepatic stem cells identified through high density complementary DNA microarrays.

Nierhoff D, Levoci L, Schulte S, Goeser T, Rogler LE, Shafritz DA.

Hepatology. 2007 Aug;46(2):535-47.

PMID:
17508344
13.

BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm.

Gouon-Evans V, Boussemart L, Gadue P, Nierhoff D, Koehler CI, Kubo A, Shafritz DA, Keller G.

Nat Biotechnol. 2006 Nov;24(11):1402-11. Epub 2006 Nov 5.

PMID:
17086172
14.

Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice.

Landis CS, Yamanouchi K, Zhou H, Mohan S, Roy-Chowdhury N, Shafritz DA, Koretsky A, Roy-Chowdhury J, Hetherington HP, Guha C.

Hepatology. 2006 Nov;44(5):1250-8.

PMID:
17058269
15.

Properties of cryopreserved fetal liver stem/progenitor cells that exhibit long-term repopulation of the normal rat liver.

Oertel M, Menthena A, Chen YQ, Shafritz DA.

Stem Cells. 2006 Oct;24(10):2244-51. Epub 2006 Jun 15.

16.

Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells.

Oertel M, Menthena A, Dabeva MD, Shafritz DA.

Gastroenterology. 2006 Feb;130(2):507-20; quiz 590.

PMID:
16472603
17.

Liver stem cells and prospects for liver reconstitution by transplanted cells.

Shafritz DA, Oertel M, Menthena A, Nierhoff D, Dabeva MD.

Hepatology. 2006 Feb;43(2 Suppl 1):S89-98. Review.

PMID:
16447292
18.

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.

Ju W, Ogawa A, Heyer J, Nierhof D, Yu L, Kucherlapati R, Shafritz DA, Böttinger EP.

Mol Cell Biol. 2006 Jan;26(2):654-67.

19.

Whole fetal liver transplantation--a new approach to cell therapy.

Oren R, Breitman Y, Gur E, Traister A, Zvibel I, Brazovsky E, Shafritz DA, Halpern Z.

Liver Transpl. 2005 Aug;11(8):929-33.

20.

Purification and characterization of mouse fetal liver epithelial cells with high in vivo repopulation capacity.

Nierhoff D, Ogawa A, Oertel M, Chen YQ, Shafritz DA.

Hepatology. 2005 Jul;42(1):130-9.

PMID:
15895427
21.

Bone marrow progenitors are not the source of expanding oval cells in injured liver.

Menthena A, Deb N, Oertel M, Grozdanov PN, Sandhu J, Shah S, Guha C, Shafritz DA, Dabeva MD.

Stem Cells. 2004;22(6):1049-61.

22.

Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays.

Petkov PM, Zavadil J, Goetz D, Chu T, Carver R, Rogler CE, Bottinger EP, Shafritz DA, Dabeva MD.

Hepatology. 2004 Mar;39(3):617-27.

PMID:
14999680
23.
24.

Hepatic stem cells and liver repopulation.

Dabeva MD, Shafritz DA.

Semin Liver Dis. 2003 Nov;23(4):349-62. Review.

PMID:
14722812
25.

Triiodothyronine and interleukin-6 (IL-6) induce expression of HGF in an immortalized rat hepatic stellate cell line.

Kariv R, Enden A, Zvibel I, Rosner G, Brill S, Shafritz DA, Halpern Z, Oren R.

Liver Int. 2003 Jun;23(3):187-93.

PMID:
12955882
26.

HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver.

Kollet O, Shivtiel S, Chen YQ, Suriawinata J, Thung SN, Dabeva MD, Kahn J, Spiegel A, Dar A, Samira S, Goichberg P, Kalinkovich A, Arenzana-Seisdedos F, Nagler A, Hardan I, Revel M, Shafritz DA, Lapidot T.

J Clin Invest. 2003 Jul;112(2):160-9.

27.

Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors.

Oertel M, Rosencrantz R, Chen YQ, Thota PN, Sandhu JS, Dabeva MD, Pacchia AL, Adelson ME, Dougherty JP, Shafritz DA.

Hepatology. 2003 May;37(5):994-1005.

PMID:
12717380
28.

Liver stem cells and model systems for liver repopulation.

Shafritz DA, Dabeva MD.

J Hepatol. 2002 Apr;36(4):552-64. Review. No abstract available.

PMID:
11943430
29.

Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells.

Sandhu JS, Petkov PM, Dabeva MD, Shafritz DA.

Am J Pathol. 2001 Oct;159(4):1323-34.

30.

Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine.

Laconi S, Pillai S, Porcu PP, Shafritz DA, Pani P, Laconi E.

Am J Pathol. 2001 Feb;158(2):771-7.

31.

Rat liver stem cells: prospects for the future.

Shafritz DA.

Hepatology. 2000 Dec;32(6):1399-400. Review. No abstract available.

PMID:
11093748
32.

Cell transplantation causes loss of gap junctions and activates GGT expression permanently in host liver.

Gupta S, Rajvanshi P, Malhi H, Slehria S, Sokhi RP, Vasa SR, Dabeva M, Shafritz DA, Kerr.

Am J Physiol Gastrointest Liver Physiol. 2000 Oct;279(4):G815-26.

33.

Identification of differentially expressed genes in epithelial stem/progenitor cells of fetal rat liver.

Petkov PM, Kim K, Sandhu J, Shafritz DA, Dabeva MD.

Genomics. 2000 Sep 1;68(2):197-209.

PMID:
10964518
34.

Proliferation and differentiation of fetal liver epithelial progenitor cells after transplantation into adult rat liver.

Dabeva MD, Petkov PM, Sandhu J, Oren R, Laconi E, Hurston E, Shafritz DA.

Am J Pathol. 2000 Jun;156(6):2017-31.

35.

Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes.

Oren R, Dabeva MD, Karnezis AN, Petkov PM, Rosencrantz R, Sandhu JP, Moss SF, Wang S, Hurston E, Laconi E, Holt PR, Thung SN, Zhu L, Shafritz DA.

Hepatology. 1999 Oct;30(4):903-13.

PMID:
10498641
36.

Direct hyperplasia does not enhance the kinetics of liver repopulation in a new model of hepatocyte transplantation in the rat.

Pani P, Laconi S, Pillai S, Scintu F, Curreli F, Shafritz DA, Laconi E.

J Hepatol. 1999 Aug;31(2):354-9.

PMID:
10453951
37.

Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver.

Ott M, Rajvanshi P, Sokhi RP, Alpini G, Aragona E, Dabeva M, Shafritz DA, Gupta S.

J Pathol. 1999 Feb;187(3):365-73.

PMID:
10398093
38.

Principles of therapeutic liver repopulation.

Grompe M, Laconi E, Shafritz DA.

Semin Liver Dis. 1999;19(1):7-14. Review.

PMID:
10349679
39.

Liver regeneration and alpha-fetoprotein messenger RNA expression in the retrorsine model for hepatocyte transplantation.

Dabeva MD, Laconi E, Oren R, Petkov PM, Hurston E, Shafritz DA.

Cancer Res. 1998 Dec 15;58(24):5825-34.

40.

Restoration of serum albumin levels in nagase analbuminemic rats by hepatocyte transplantation.

Oren R, Dabeva MD, Petkov PM, Hurston E, Laconi E, Shafritz DA.

Hepatology. 1999 Jan;29(1):75-81.

PMID:
9862853
41.

Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine.

Laconi E, Oren R, Mukhopadhyay DK, Hurston E, Laconi S, Pani P, Dabeva MD, Shafritz DA.

Am J Pathol. 1998 Jul;153(1):319-29.

42.

Differentiation of pancreatic epithelial progenitor cells into hepatocytes following transplantation into rat liver.

Dabeva MD, Hwang SG, Vasa SR, Hurston E, Novikoff PM, Hixson DC, Gupta S, Shafritz DA.

Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7356-61.

43.

Cell type-specific mechanisms regulate hepatitis B virus transgene expression in liver and other organs.

Aragona E, Burk RD, Ott M, Shafritz DA, Gupta S.

J Pathol. 1996 Dec;180(4):441-9.

PMID:
9014867
44.

Phyllanthus amarus down-regulates hepatitis B virus mRNA transcription and replication.

Lee CD, Ott M, Thyagarajan SP, Shafritz DA, Burk RD, Gupta S.

Eur J Clin Invest. 1996 Dec;26(12):1069-76.

PMID:
9013081
45.

Expression of messenger RNA for liver functions following 70% and 90% hepatectomy.

Tygstrup N, Jensen SA, Krog B, Pietrangelo A, Shafritz DA.

J Hepatol. 1996 Jul;25(1):72-8.

PMID:
8836904
46.

Synthetic retinoids for the secondary prevention of hepatocellular carcinoma.

Shafritz DA.

N Engl J Med. 1996 Jun 13;334(24):1600-1. No abstract available.

PMID:
8628344
47.
48.

Gene expression of urea cycle enzymes following two-thirds partial hepatectomy in the rat.

Tygstrup N, Bak S, Krog B, Pietrangelo A, Shafritz DA.

J Hepatol. 1995 Mar;22(3):349-55.

PMID:
7608487
49.

Outcome of perinatal hepatitis B virus exposure is dependent on maternal virus load.

Burk RD, Hwang LY, Ho GY, Shafritz DA, Beasley RP.

J Infect Dis. 1994 Dec;170(6):1418-23.

PMID:
7995980
50.

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