Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 10

1.

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Abdul-Aziz AM, Sun Y, Hellmich C, Marlein CR, Mistry J, Forde E, Piddock RE, Shafat MS, Morfakis A, Mehta T, Di Palma F, Macaulay I, Ingham CJ, Haestier A, Collins A, Campisi J, Bowles KM, Rushworth SA.

Blood. 2019 Jan 31;133(5):446-456. doi: 10.1182/blood-2018-04-845420. Epub 2018 Nov 6.

PMID:
30401703
2.

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.

Piddock RE, Marlein CR, Abdul-Aziz A, Shafat MS, Auger MJ, Bowles KM, Rushworth SA.

J Hematol Oncol. 2018 May 16;11(1):66. doi: 10.1186/s13045-018-0614-4.

3.

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.

Abdul-Aziz AM, Shafat MS, Sun Y, Marlein CR, Piddock RE, Robinson SD, Edwards DR, Zhou Z, Collins A, Bowles KM, Rushworth SA.

Oncogene. 2018 May;37(20):2676-2686. doi: 10.1038/s41388-018-0151-1. Epub 2018 Feb 28.

PMID:
29487418
4.

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.

Marlein CR, Zaitseva L, Piddock RE, Robinson SD, Edwards DR, Shafat MS, Zhou Z, Lawes M, Bowles KM, Rushworth SA.

Blood. 2017 Oct 5;130(14):1649-1660. doi: 10.1182/blood-2017-03-772939. Epub 2017 Jul 21.

PMID:
28733324
5.

The bone marrow microenvironment - Home of the leukemic blasts.

Shafat MS, Gnaneswaran B, Bowles KM, Rushworth SA.

Blood Rev. 2017 Sep;31(5):277-286. doi: 10.1016/j.blre.2017.03.004. Epub 2017 Mar 12. Review.

PMID:
28318761
6.

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.

Shafat MS, Oellerich T, Mohr S, Robinson SD, Edwards DR, Marlein CR, Piddock RE, Fenech M, Zaitseva L, Abdul-Aziz A, Turner J, Watkins JA, Lawes M, Bowles KM, Rushworth SA.

Blood. 2017 Mar 9;129(10):1320-1332. doi: 10.1182/blood-2016-08-734798. Epub 2017 Jan 3.

PMID:
28049638
7.

MIF-Induced Stromal PKCβ/IL8 Is Essential in Human Acute Myeloid Leukemia.

Abdul-Aziz AM, Shafat MS, Mehta TK, Di Palma F, Lawes MJ, Rushworth SA, Bowles KM.

Cancer Res. 2017 Jan 15;77(2):303-311. doi: 10.1158/0008-5472.CAN-16-1095. Epub 2016 Nov 21.

8.

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection.

Pillinger G, Loughran NV, Piddock RE, Shafat MS, Zaitseva L, Abdul-Aziz A, Lawes MJ, Bowles KM, Rushworth SA.

Oncotarget. 2016 Jun 28;7(26):39784-39795. doi: 10.18632/oncotarget.9289.

9.

Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells.

Rushworth SA, Pillinger G, Abdul-Aziz A, Piddock R, Shafat MS, Murray MY, Zaitseva L, Lawes MJ, MacEwan DJ, Bowles KM.

Lancet Haematol. 2015 May;2(5):e204-11. doi: 10.1016/S2352-3026(15)00046-0. Epub 2015 Apr 14.

PMID:
26688095
10.

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML.

Zaitseva L, Murray MY, Shafat MS, Lawes MJ, MacEwan DJ, Bowles KM, Rushworth SA.

Oncotarget. 2014 Oct 30;5(20):9930-8.

Supplemental Content

Loading ...
Support Center