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Items: 19


Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses.

Spencer S, Köstel Bal S, Egner W, Lango Allen H, Raza SI, Ma CA, Gürel M, Zhang Y, Sun G, Sabroe RA, Greene D, Rae W, Shahin T, Kania K, Ardy RC, Thian M, Staples E, Pecchia-Bekkum A, Worrall WPM, Stephens J, Brown M, Tuna S, York M, Shackley F, Kerrin D, Sargur R, Condliffe A, Tipu HN, Kuehn HS, Rosenzweig SD, Turro E, Tavaré S, Thrasher AJ, Jodrell DI, Smith KGC, Boztug K, Milner JD, Thaventhiran JED.

J Exp Med. 2019 Jun 24. pii: jem.20190344. doi: 10.1084/jem.20190344. [Epub ahead of print]


Compound heterozygous variants in NBAS as a cause of atypical osteogenesis imperfecta.

Balasubramanian M, Hurst J, Brown S, Bishop NJ, Arundel P, DeVile C, Pollitt RC, Crooks L, Longman D, Caceres JF, Shackley F, Connolly S, Payne JH, Offiah AC, Hughes D; DDD Study, Parker MJ, Hide W, Skerry TM.

Bone. 2017 Jan;94:65-74. doi: 10.1016/j.bone.2016.10.023. Epub 2016 Oct 24.


Vitamin D and antimicrobial peptide levels in patients with atopic dermatitis and atopic dermatitis complicated by eczema herpeticum: A pilot study.

Albenali LH, Danby S, Moustafa M, Brown K, Chittock J, Shackley F, Cork MJ.

J Allergy Clin Immunol. 2016 Dec;138(6):1715-1719.e4. doi: 10.1016/j.jaci.2016.05.039. Epub 2016 Jul 14. No abstract available.


Prevalence, incidence, and associated risk factors of tuberculosis in children with HIV living in the UK and Ireland (CHIPS): a cohort study.

Turkova A, Chappell E, Judd A, Goodall RL, Welch SB, Foster C, Riordan A, Shingadia D, Shackley F, Doerholt K, Gibb DM, Collins IJ; Collaborative HIV Paediatric Study (CHIPS) Steering Committee.

Lancet HIV. 2015 Dec;2(12):e530-9. doi: 10.1016/S2352-3018(15)00200-3. Epub 2015 Oct 29.


Extreme growth failure is a common presentation of ligase IV deficiency.

Murray JE, Bicknell LS, Yigit G, Duker AL, van Kogelenberg M, Haghayegh S, Wieczorek D, Kayserili H, Albert MH, Wise CA, Brandon J, Kleefstra T, Warris A, van der Flier M, Bamforth JS, Doonanco K, Adès L, Ma A, Field M, Johnson D, Shackley F, Firth H, Woods CG, Nürnberg P, Gatti RA, Hurles M, Bober MB, Wollnik B, Jackson AP.

Hum Mutat. 2014 Jan;35(1):76-85. doi: 10.1002/humu.22461. Epub 2013 Nov 8.


Accidental cutaneous burns secondary to salbutamol metered dose inhaler.

Kale A, Shackley F.

Case Rep Med. 2010;2010:201809. doi: 10.1155/2010/201809. Epub 2010 Dec 27.


Susceptibility to mycobacterial infection in a young man with a hypoglossal nerve palsy: the hunt for an immunological defect.

Cottle LE, Sargur R, Egner W, Shackley F, Greig J.

JRSM Short Rep. 2010 Jul 30;1(2):21. doi: 10.1258/shorts.2010.010018. No abstract available.


Clinical and immunological overlap between autoimmune lymphoproliferative syndrome and common variable immunodeficiency.

Rensing-Ehl A, Warnatz K, Fuchs S, Schlesier M, Salzer U, Draeger R, Bondzio I, Joos Y, Janda A, Gomes M, Abinun M, Hambleton S, Cant A, Shackley F, Flood T, Waruiru C, Beutel K, Siepermann K, Dueckers G, Niehues T, Wiesel T, Schuster V, Seidel MG, Minkov M, Sirkiä K, Kopp MV, Korhonen M, Schwarz K, Ehl S, Speckmann C.

Clin Immunol. 2010 Dec;137(3):357-65. doi: 10.1016/j.clim.2010.08.008. Epub 2010 Sep 15.


Intracranial non-Langerhans cell histiocytosis presenting as an isolated intraparenchymal lesion.

Rajaram S, Wharton SB, Shackley F, Raghavan A, Connolly DJ.

Pediatr Radiol. 2010 Dec;40 Suppl 1:S145-9. doi: 10.1007/s00247-010-1768-6. Epub 2010 Jul 16.


Onchocercosis mansonella co-infection presenting as a subcutaneous nodule in a child.

Davies JQ, Cohen MC, Shackley F, Clarke TC, Page RE.

Fetal Pediatr Pathol. 2007 Jan-Feb;26(1):47-53.


Capsular serotype-specific attack rates and duration of carriage of Streptococcus pneumoniae in a population of children.

Sleeman KL, Griffiths D, Shackley F, Diggle L, Gupta S, Maiden MC, Moxon ER, Crook DW, Peto TE.

J Infect Dis. 2006 Sep 1;194(5):682-8. Epub 2006 Jul 25.


Return of Haemophilus influenzae type b infections.

Fenton P, Mayer A, Ridgway E, Lakshman R, Shackley F.

Lancet. 2003 May 3;361(9368):1564. No abstract available.


Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group.

Shackley F, Knox K, Morris JB, Crook D, Griffiths D, Mayon-White R, George R, Willocks L, Moxon E.

Arch Dis Child. 2000 Sep;83(3):231-3.


Safety, immunogenicity, and induction of immunologic memory by a serogroup C meningococcal conjugate vaccine in infants: A randomized controlled trial.

MacLennan JM, Shackley F, Heath PT, Deeks JJ, Flamank C, Herbert M, Griffiths H, Hatzmann E, Goilav C, Moxon ER.

JAMA. 2000 Jun 7;283(21):2795-801.


Poor response to hib (PRP-T) vaccine when combined with an acellular pertussis/diphtheria/tetanus vaccine for primary immunization of infants.

Bell F, Health P, Shackley F, Maclennan J, Herbert M, Shearstone N, Diggle L, Moxon ER, Finn A.

Biologicals. 1999 Jun;27(2):113. No abstract available.


Adverse effects and sero-responses to an acellular pertussis/diphtheria/tetanus vaccine when combined with Haemophilus influenzae type b vaccine in an accelerated schedule.

Bell F, Heath P, MacLennan J, Shackley F, Shearstone N, Diggle L, Thornton C, Griffiths H, Moxon ER, Finn A.

Eur J Pediatr. 1999 Apr;158(4):329-36.


Effect of combination with an acellular pertussis, diphtheria, tetanus vaccine on antibody response to Hib vaccine (PRP-T).

Bell F, Heath P, Shackley F, MacLennan J, Shearstone N, Diggle L, Griffiths H, Moxon ER, Finn A.

Vaccine. 1998 Apr;16(6):637-42.


Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children.

Ryan M, Murphy G, Ryan E, Nilsson L, Shackley F, Gothefors L, Oymar K, Miller E, Storsaeter J, Mills KH.

Immunology. 1998 Jan;93(1):1-10.


Trough-only monitoring of serum vancomycin concentrations in neonates.

Shackley F, Roberts P, Heath P, Bowler I, Saunders NJ.

J Antimicrob Chemother. 1998 Jan;41(1):141-2. No abstract available.


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