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Items: 6

1.

Nrf2 mitigates LRRK2- and α-synuclein-induced neurodegeneration by modulating proteostasis.

Skibinski G, Hwang V, Ando DM, Daub A, Lee AK, Ravisankar A, Modan S, Finucane MM, Shaby BA, Finkbeiner S.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1165-1170. doi: 10.1073/pnas.1522872114. Epub 2016 Dec 27.

2.

A three-groups model for high-throughput survival screens.

Shaby BA, Skibinski G, Ando M, LaDow ES, Finkbeiner S.

Biometrics. 2016 Sep;72(3):936-44. doi: 10.1111/biom.12479. Epub 2016 Jan 28.

3.

Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration.

Tsvetkov AS, Arrasate M, Barmada S, Ando DM, Sharma P, Shaby BA, Finkbeiner S.

Nat Chem Biol. 2013 Sep;9(9):586-92. doi: 10.1038/nchembio.1308. Epub 2013 Jul 21.

4.

A HIERARCHICAL MAX-STABLE SPATIAL MODEL FOR EXTREME PRECIPITATION.

Reich BJ, Shaby BA.

Ann Appl Stat. 2012;6(4):1430-1451.

5.

Identifying polyglutamine protein species in situ that best predict neurodegeneration.

Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S.

Nat Chem Biol. 2011 Oct 30;7(12):925-34. doi: 10.1038/nchembio.694. Erratum in: Nat Chem Biol. 2012 Mar;8(3):318.

6.

Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis.

Miller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S.

J Neurosci. 2010 Aug 4;30(31):10541-50. doi: 10.1523/JNEUROSCI.0146-10.2010.

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