Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 54

1.

The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.

Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M.

EMBO Mol Med. 2018 Mar;10(3). pii: e8047. doi: 10.15252/emmm.201708047.

2.

Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1.

Shabalina IG, Vyssokikh MY, Gibanova N, Csikasz RI, Edgar D, Hallden-Waldemarson A, Rozhdestvenskaya Z, Bakeeva LE, Vays VB, Pustovidko AV, Skulachev MV, Cannon B, Skulachev VP, Nedergaard J.

Aging (Albany NY). 2017 Feb 15;9(2):315-339. doi: 10.18632/aging.101174.

3.

UCP1 inhibition in Cidea-overexpressing mice is physiologically counteracted by brown adipose tissue hyperrecruitment.

Fischer AW, Shabalina IG, Mattsson CL, Abreu-Vieira G, Cannon B, Nedergaard J, Petrovic N.

Am J Physiol Endocrinol Metab. 2017 Jan 1;312(1):E72-E87. doi: 10.1152/ajpendo.00284.2016. Epub 2016 Dec 6.

4.

Mitochondria-targeted dodecyltriphenylphosphonium (C12TPP) combats high-fat-diet-induced obesity in mice.

Kalinovich AV, Mattsson CL, Youssef MR, Petrovic N, Ost M, Skulachev VP, Shabalina IG.

Int J Obes (Lond). 2016 Dec;40(12):1864-1874. doi: 10.1038/ijo.2016.146. Epub 2016 Aug 18.

5.

Corrigendum: Cidea improves the metabolic profile through expansion of adipose tissue.

Abreu-Vieira G, Fischer AW, Mattsson C, de Jong JM, Shabalina IG, Rydén M, Laurencikiene J, Arner P, Cannon B, Nedergaard J, Petrovic N.

Nat Commun. 2016 Aug 4;7:12395. doi: 10.1038/ncomms12395. No abstract available.

6.

Cidea improves the metabolic profile through expansion of adipose tissue.

Abreu-Vieira G, Fischer AW, Mattsson C, de Jong JM, Shabalina IG, Rydén M, Laurencikiene J, Arner P, Cannon B, Nedergaard J, Petrovic N.

Nat Commun. 2015 Jun 29;6:7433. doi: 10.1038/ncomms8433.

PMID:
26118629
7.

Novel Mitochondrial Cationic Uncoupler C4R1 Is an Effective Treatment for Combating Obesity in Mice.

Kalinovich AV, Shabalina IG.

Biochemistry (Mosc). 2015 May;80(5):620-8. doi: 10.1134/S0006297915050156.

8.

Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria.

Shabalina IG, Kalinovich AV, Cannon B, Nedergaard J.

Arch Toxicol. 2016 May;90(5):1117-28. doi: 10.1007/s00204-015-1535-4. Epub 2015 Jun 4.

9.

The Environmental Pollutants Perfluorooctane Sulfonate and Perfluorooctanoic Acid Upregulate Uncoupling Protein 1 (UCP1) in Brown-Fat Mitochondria Through a UCP1-Dependent Reduction in Food Intake.

Shabalina IG, Kramarova TV, Mattsson CL, Petrovic N, Rahman Qazi M, Csikasz RI, Chang SC, Butenhoff J, DePierre JW, Cannon B, Nedergaard J.

Toxicol Sci. 2015 Aug;146(2):334-43. doi: 10.1093/toxsci/kfv098. Epub 2015 May 21.

PMID:
26001964
10.

Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice.

Shabalina IG, Landreh L, Edgar D, Hou M, Gibanova N, Atanassova N, Petrovic N, Hultenby K, Söder O, Nedergaard J, Svechnikov K.

FASEB J. 2015 Aug;29(8):3274-86. doi: 10.1096/fj.15-271825. Epub 2015 Apr 21.

PMID:
25900807
11.

Age-associated murine cardiac lesions are attenuated by the mitochondria-targeted antioxidant SkQ1.

Manskikh VN, Gancharova OS, Nikiforova AI, Krasilshchikova MS, Shabalina IG, Egorov MV, Karger EM, Milanovsky GE, Galkin II, Skulachev VP, Zinovkin RA.

Histol Histopathol. 2015 Mar;30(3):353-60. doi: 10.14670/HH-30.353. Epub 2014 Oct 17.

PMID:
25323729
12.

ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence.

Shabalina IG, Vrbacký M, Pecinová A, Kalinovich AV, Drahota Z, Houštěk J, Mráček T, Cannon B, Nedergaard J.

Biochim Biophys Acta. 2014 Dec;1837(12):2017-2030. doi: 10.1016/j.bbabio.2014.04.005. Epub 2014 Apr 24.

13.

In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice.

Logan A, Shabalina IG, Prime TA, Rogatti S, Kalinovich AV, Hartley RC, Budd RC, Cannon B, Murphy MP.

Aging Cell. 2014 Aug;13(4):765-8. doi: 10.1111/acel.12212. Epub 2014 Mar 13.

14.

UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic.

Shabalina IG, Petrovic N, de Jong JM, Kalinovich AV, Cannon B, Nedergaard J.

Cell Rep. 2013 Dec 12;5(5):1196-203. doi: 10.1016/j.celrep.2013.10.044. Epub 2013 Nov 27.

15.

Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation.

Rupprecht A, Bräuer AU, Smorodchenko A, Goyn J, Hilse KE, Shabalina IG, Infante-Duarte C, Pohl EE.

PLoS One. 2012;7(8):e41406. doi: 10.1371/journal.pone.0041406. Epub 2012 Aug 3.

16.

Reduced content of α-synuclein in peripheral blood leukocytes of patients with LRRK2-associated Parkinson's disease.

Pchelina SN, Emelyanov AK, Yakimovskii AF, Miller DW, Shabalina IG, Drozdova AS, Schwarzman AL.

Bull Exp Biol Med. 2011 Apr;150(6):679-81.

PMID:
22235415
17.

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents.

Anisimov VN, Egorov MV, Krasilshchikova MS, Lyamzaev KG, Manskikh VN, Moshkin MP, Novikov EA, Popovich IG, Rogovin KA, Shabalina IG, Shekarova ON, Skulachev MV, Titova TV, Vygodin VA, Vyssokikh MY, Yurova MN, Zabezhinsky MA, Skulachev VP.

Aging (Albany NY). 2011 Nov;3(11):1110-9.

18.

Mitochondrial ('mild') uncoupling and ROS production: physiologically relevant or not?

Shabalina IG, Nedergaard J.

Biochem Soc Trans. 2011 Oct;39(5):1305-9. doi: 10.1042/BST0391305. Review.

PMID:
21936806
19.

Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic Goto-Kakizaki rats.

Öberg AI, Yassin K, Csikasz RI, Dehvari N, Shabalina IG, Hutchinson DS, Wilcke M, Östenson CG, Bengtsson T.

PLoS One. 2011;6(7):e22510. doi: 10.1371/journal.pone.0022510. Epub 2011 Jul 26.

20.

Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice.

Nabben M, Shabalina IG, Moonen-Kornips E, van Beurden D, Cannon B, Schrauwen P, Nedergaard J, Hoeks J.

Biochim Biophys Acta. 2011 Sep;1807(9):1095-105. doi: 10.1016/j.bbabio.2011.04.003. Epub 2011 May 1.

21.

Increased fatigue resistance linked to Ca2+-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice.

Bruton JD, Aydin J, Yamada T, Shabalina IG, Ivarsson N, Zhang SJ, Wada M, Tavi P, Nedergaard J, Katz A, Westerblad H.

J Physiol. 2010 Nov 1;588(Pt 21):4275-88. doi: 10.1113/jphysiol.2010.198598.

22.

Caveolin-1-ablated mice survive in cold by nonshivering thermogenesis despite desensitized adrenergic responsiveness.

Mattsson CL, Csikasz RI, Shabalina IG, Nedergaard J, Cannon B.

Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E374-83. doi: 10.1152/ajpendo.00071.2010. Epub 2010 Jun 8.

23.

Uncoupling protein-1 is not leaky.

Shabalina IG, Ost M, Petrovic N, Vrbacky M, Nedergaard J, Cannon B.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):773-84. doi: 10.1016/j.bbabio.2010.04.007. Epub 2010 Apr 14.

24.

Cold tolerance of UCP1-ablated mice: a skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects.

Shabalina IG, Hoeks J, Kramarova TV, Schrauwen P, Cannon B, Nedergaard J.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):968-80. doi: 10.1016/j.bbabio.2010.02.033. Epub 2010 Mar 19.

25.

Ultraendurance exercise increases the production of reactive oxygen species in isolated mitochondria from human skeletal muscle.

Sahlin K, Shabalina IG, Mattsson CM, Bakkman L, Fernström M, Rozhdestvenskaya Z, Enqvist JK, Nedergaard J, Ekblom B, Tonkonogi M.

J Appl Physiol (1985). 2010 Apr;108(4):780-7. doi: 10.1152/japplphysiol.00966.2009. Epub 2010 Jan 28.

26.
27.

Nonshivering thermogenesis protects against defective calcium handling in muscle.

Aydin J, Shabalina IG, Place N, Reiken S, Zhang SJ, Bellinger AM, Nedergaard J, Cannon B, Marks AR, Bruton JD, Westerblad H.

FASEB J. 2008 Nov;22(11):3919-24. doi: 10.1096/fj.08-113712. Epub 2008 Aug 7.

28.

Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist.

Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E287-96. doi: 10.1152/ajpendo.00035.2008. Epub 2008 May 20.

29.

Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism.

Shabalina IG, Backlund EC, Bar-Tana J, Cannon B, Nedergaard J.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):642-50. doi: 10.1016/j.bbabio.2008.04.038. Epub 2008 May 1.

30.

Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform.

Kramarova TV, Shabalina IG, Andersson U, Westerberg R, Carlberg I, Houstek J, Nedergaard J, Cannon B.

FASEB J. 2008 Jan;22(1):55-63. Epub 2007 Jul 31.

PMID:
17666453
31.

Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1.

Ocloo A, Shabalina IG, Nedergaard J, Brand MD.

Am J Physiol Regul Integr Comp Physiol. 2007 Sep;293(3):R1086-93. Epub 2007 Jul 3.

32.

Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase.

Hutchinson DS, Csikasz RI, Yamamoto DL, Shabalina IG, Wikström P, Wilcke M, Bengtsson T.

Cell Signal. 2007 Jul;19(7):1610-20. Epub 2007 Feb 21.

PMID:
17391917
33.

Reduced efficiency, but increased fat oxidation, in mitochondria from human skeletal muscle after 24-h ultraendurance exercise.

Fernström M, Bakkman L, Tonkonogi M, Shabalina IG, Rozhdestvenskaya Z, Mattsson CM, Enqvist JK, Ekblom B, Sahlin K.

J Appl Physiol (1985). 2007 May;102(5):1844-9. Epub 2007 Jan 18.

34.

Differential role of Presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts.

Behbahani H, Shabalina IG, Wiehager B, Concha H, Hultenby K, Petrovic N, Nedergaard J, Winblad B, Cowburn RF, Ankarcrona M.

J Neurosci Res. 2006 Sep;84(4):891-902.

PMID:
16883555
36.

Uncoupling proteins: a role in protection against reactive oxygen species--or not?

Cannon B, Shabalina IG, Kramarova TV, Petrovic N, Nedergaard J.

Biochim Biophys Acta. 2006 May-Jun;1757(5-6):449-58. Epub 2006 May 17. Review.

37.

UCP1 and defense against oxidative stress. 4-Hydroxy-2-nonenal effects on brown fat mitochondria are uncoupling protein 1-independent.

Shabalina IG, Petrovic N, Kramarova TV, Hoeks J, Cannon B, Nedergaard J.

J Biol Chem. 2006 May 19;281(20):13882-93. Epub 2006 Mar 16.

38.

ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue.

Westerberg R, Månsson JE, Golozoubova V, Shabalina IG, Backlund EC, Tvrdik P, Retterstøl K, Capecchi MR, Jacobsson A.

J Biol Chem. 2006 Feb 24;281(8):4958-68. Epub 2005 Dec 2.

39.

SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity.

Silva JP, Shabalina IG, Dufour E, Petrovic N, Backlund EC, Hultenby K, Wibom R, Nedergaard J, Cannon B, Larsson NG.

EMBO J. 2005 Dec 7;24(23):4061-70. Epub 2005 Nov 10.

40.

Inhibitory effects of halothane on the thermogenic pathway in brown adipocytes: localization to adenylyl cyclase and mitochondrial fatty acid oxidation.

Ohlson KB, Shabalina IG, Lennström K, Backlund EC, Mohell N, Bronnikov GE, Lindahl SG, Cannon B, Nedergaard J.

Biochem Pharmacol. 2004 Aug 1;68(3):463-77.

PMID:
15242813
41.

Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids.

Shabalina IG, Jacobsson A, Cannon B, Nedergaard J.

J Biol Chem. 2004 Sep 10;279(37):38236-48. Epub 2004 Jun 18.

42.

Effect of transforming growth factor-beta on calcium homeostasis in prostate carcinoma cells.

Gizatullina ZZ, Grapengiesser E, Shabalina IG, Nedergaard J, Heldin CH, Aspenström P.

Biochem Biophys Res Commun. 2003 May 16;304(4):643-9.

PMID:
12727202
43.

Generation of reactive oxygen species by mitochondria in senescence-accelerated OXYS rats.

Men'shchikova EB, Shabalina IG, Zenkov NK, Kolosova NG.

Bull Exp Biol Med. 2002 Feb;133(2):175-7.

PMID:
12428288
44.

Dynamics of structural and functional changes in hepatocyte mitochondria of senescence-accelerated OXYS rats.

Kolosova NG, Aidagulova SV, Nepomnyashchikh GI, Shabalina IG, Shalbueva NI.

Bull Exp Biol Med. 2001 Aug;132(2):814-9.

PMID:
11713575
45.

[Use of mirtilene forte and adrusen zinco for correction of oxidative lesions in mitochondria in rats OXYS with inherited hyperproduction of free radicals].

Shabalina IG, Shalbueva NI, Dikalova AE, Sinitsyna OI, Krysanova ZhS, Kolosova NG.

Eksp Klin Farmakol. 2001 Jul-Aug;64(4):34-6. Russian.

PMID:
11589106
46.
47.

Effects of the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid, on apoptosis in human hepatoma HepG2 cells.

Shabalina IG, Panaretakis T, Bergstrand A, DePierre JW.

Carcinogenesis. 1999 Dec;20(12):2237-46.

PMID:
10590214
48.

[Level of tocopherol and lipid peroxidation products in tissues of rats with an inherited ability to hyperproduce reactive free radicals].

Kolosova NG, Solov'eva NA, Shabalina IG, Salganik RI.

Biull Eksp Biol Med. 1996 Mar;121(3):282-4. Russian. No abstract available.

PMID:
8688528
49.

[Oxidative phosphorylation activity, F0F1-ATPase and level of liver mitochondrial cytochromes in rats with congenitally increased ability for free radical formation].

Shabalina IG, Kolosova NG, Grishanova AIu, Solov'ev VN, Salganik RI, Solov'eva NA.

Biokhimiia. 1995 Dec;60(12):2045-52. Russian.

PMID:
8600999
50.

[Physico-chemical properties of the membrane and functional status of liver mitochondria from rats with congenital tendency toward increased radical formation].

Salganik RI, Shabalina IG, Kolosova NG, Solov'ev VN, Solov'eva NA, Kolpakov AR.

Biull Eksp Biol Med. 1995 Jun;119(6):628-31. Russian. No abstract available.

PMID:
8589390

Supplemental Content

Loading ...
Support Center