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Items: 1 to 50 of 238

1.

Elderly patients and PD-L1-positive advanced non-small cell lung cancer: is pembrolizumab monotherapy effective and safe?

Gridelli C, Sgambato A.

Ann Transl Med. 2019 Dec;7(Suppl 8):S282. doi: 10.21037/atm.2019.12.31. No abstract available.

2.

Extracellular Vesicles and Cancer: A Focus on Metabolism, Cytokines, and Immunity.

Lucchetti D, Ricciardi Tenore C, Colella F, Sgambato A.

Cancers (Basel). 2020 Jan 10;12(1). pii: E171. doi: 10.3390/cancers12010171. Review.

3.

CD147 Promotes Cell Small Extracellular Vesicles Release during Colon Cancer Stem Cells Differentiation and Triggers Cellular Changes in Recipient Cells.

Lucchetti D, Colella F, Perelli L, Ricciardi-Tenore C, Calapà F, Fiori ME, Carbone F, De Maria R, Sgambato A.

Cancers (Basel). 2020 Jan 21;12(2). pii: E260. doi: 10.3390/cancers12020260.

4.

Low-intensity pulsed ultrasound affects growth, differentiation, migration, and epithelial-to-mesenchymal transition of colorectal cancer cells.

Lucchetti D, Perelli L, Colella F, Ricciardi-Tenore C, Scoarughi GL, Barbato G, Boninsegna A, De Maria R, Sgambato A.

J Cell Physiol. 2020 Jan 22. doi: 10.1002/jcp.29423. [Epub ahead of print]

PMID:
31967331
5.

Heat shock proteins in thyroid malignancies: Potential therapeutic targets for poorly-differentiated and anaplastic tumours?

Lettini G, Pietrafesa M, Lepore S, Maddalena F, Crispo F, Sgambato A, Esposito F, Landriscina M.

Mol Cell Endocrinol. 2020 Feb 15;502:110676. doi: 10.1016/j.mce.2019.110676. Epub 2019 Dec 6. Review.

PMID:
31812782
6.

Exploring the Molecular Crosstalk between Pancreatic Bud and Mesenchyme in Embryogenesis: Novel Signals Involved.

Guerriero I, De Angelis MT, D'Angelo F, Leveque R, Savignano E, Roberto L, Lucci V, Mazzone P, Laurino S, Storto G, Nardelli A, Sgambato A, Ceccarelli M, De Felice M, Amendola E, Falco G.

Int J Mol Sci. 2019 Oct 3;20(19). pii: E4900. doi: 10.3390/ijms20194900.

7.

Cardiovascular Risk Factors and Timing of Anthracyclines and Trastuzumab Cardiac Toxicity.

Canale ML, Camerini A, Huqi A, Lilli A, Bisceglia I, Parrini I, Lestuzzi C, Del Meglio J, Donati S, Venturini E, Sgambato A, Tarantini L, Amoroso D, Casolo G.

Anticancer Res. 2019 Oct;39(10):5741-5745. doi: 10.21873/anticanres.13775.

PMID:
31570476
8.

BRAF Inhibitors in Thyroid Cancer: Clinical Impact, Mechanisms of Resistance and Future Perspectives.

Crispo F, Notarangelo T, Pietrafesa M, Lettini G, Storto G, Sgambato A, Maddalena F, Landriscina M.

Cancers (Basel). 2019 Sep 18;11(9). pii: E1388. doi: 10.3390/cancers11091388. Review.

9.

The predictive value of CSF multiple assay in multiple sclerosis: A single center experience.

De Fino C, Lucchini M, Lucchetti D, Nociti V, Losavio FA, Bianco A, Colella F, Ricciardi-Tenore C, Sgambato A, Mirabella M.

Mult Scler Relat Disord. 2019 Oct;35:176-181. doi: 10.1016/j.msard.2019.07.030. Epub 2019 Jul 28.

PMID:
31394405
10.

Adapting and Surviving: Intra and Extra-Cellular Remodeling in Drug-Resistant Gastric Cancer Cells.

Russi S, Verma HK, Laurino S, Mazzone P, Storto G, Nardelli A, Zoppoli P, Calice G, La Rocca F, Sgambato A, Lucci V, Falco G, Ruggieri V.

Int J Mol Sci. 2019 Jul 31;20(15). pii: E3736. doi: 10.3390/ijms20153736. Review.

11.

Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression.

Crispo F, Condelli V, Lepore S, Notarangelo T, Sgambato A, Esposito F, Maddalena F, Landriscina M.

Cells. 2019 Jul 30;8(8). pii: E798. doi: 10.3390/cells8080798. Review.

12.

Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice.

Sacco A, Bruno A, Contursi A, Dovizio M, Tacconelli S, Ricciotti E, Guillem-Llobat P, Salvatore T, Di Francesco L, Fullone R, Ballerini P, Arena V, Alberti S, Liu G, Gong Y, Sgambato A, Patrono C, FitzGerald GA, Yu Y, Patrignani P.

J Pharmacol Exp Ther. 2019 Sep;370(3):416-426. doi: 10.1124/jpet.119.259382. Epub 2019 Jun 27.

PMID:
31248980
13.

Sub-chronic palladium nanoparticle effects on the endocrine reproductive system of female Wistar rats: Preliminary data.

Leso V, Fontana L, Marinaccio A, Leopold K, Fanali C, Lucchetti D, Sgambato A, Iavicoli I.

Toxicol Ind Health. 2019 Jun;35(6):403-409. doi: 10.1177/0748233719851702. Epub 2019 May 26.

PMID:
31131740
14.

Anti-tumor necrosis factor α therapy associates to type 17 helper T lymphocytes immunological shift and significant microbial changes in dextran sodium sulphate colitis.

Petito V, Graziani C, Lopetuso LR, Fossati M, Battaglia A, Arena V, Scannone D, Quaranta G, Quagliariello A, Del Chierico F, Putignani L, Masucci L, Sanguinetti M, Sgambato A, Gasbarrini A, Scaldaferri F.

World J Gastroenterol. 2019 Mar 28;25(12):1465-1477. doi: 10.3748/wjg.v25.i12.1465.

15.

TNF-Stimulated Gene-6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells.

Romano B, Elangovan S, Erreni M, Sala E, Petti L, Kunderfranco P, Massimino L, Restelli S, Sinha S, Lucchetti D, Anselmo A, Colombo FS, Stravalaci M, Arena V, D'Alessio S, Ungaro F, Inforzato A, Izzo AA, Sgambato A, Day AJ, Vetrano S.

Stem Cells. 2019 Jul;37(7):973-987. doi: 10.1002/stem.3010. Epub 2019 May 14.

PMID:
30942926
16.

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.

Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G.

Cancer Cell. 2019 Feb 11;35(2):204-220.e9. doi: 10.1016/j.ccell.2019.01.006.

17.

Aspirin inhibits cancer stem cells properties and growth of glioblastoma multiforme through Rb1 pathway modulation.

Pozzoli G, Marei HE, Althani A, Boninsegna A, Casalbore P, Marlier LNJL, Lanzilli G, Zonfrillo M, Petrucci G, Rocca B, Navarra P, Sgambato A, Cenciarelli C.

J Cell Physiol. 2019 Jan 30. doi: 10.1002/jcp.28194. [Epub ahead of print]

PMID:
30701538
18.

Combination of ω-3 fatty acids and cisplatin as a potential alternative strategy for personalized therapy of metastatic melanoma: an in-vitro study.

Ottes Vasconcelos R, Serini S, de Souza Votto AP, Santos Trindade G, Fanali C, Sgambato A, Calviello G.

Melanoma Res. 2019 Jun;29(3):270-280. doi: 10.1097/CMR.0000000000000564.

PMID:
30550405
19.

The role of extracellular vesicles as biomarkers in colorectal cancer.

Lucchetti D, Litta F, Ratto C, Sgambato A.

Tech Coloproctol. 2018 Dec;22(12):989-990. doi: 10.1007/s10151-018-1880-4. Epub 2018 Nov 16. No abstract available.

PMID:
30446918
20.

IFN-γ and other serum cytokines in head and neck squamous cell carcinomas.

Bussu F, Graziani C, Gallus R, Cittadini A, Galli J, DE Corso E, DI Cintio G, Corbi M, Almadori G, Boninsegna A, Paludetti G, Sgambato A.

Acta Otorhinolaryngol Ital. 2018 Apr;38(2):94-102. doi: 10.14639/0392-100X-1530.

21.

Lung cancer, elderly and immune checkpoint inhibitors.

Casaluce F, Sgambato A, Maione P, Spagnuolo A, Gridelli C.

J Thorac Dis. 2018 May;10(Suppl 13):S1474-S1481. doi: 10.21037/jtd.2018.05.90. Review.

22.

Extracellular Vesicles in Oncology: Progress and Pitfalls in the Methods of Isolation and Analysis.

Lucchetti D, Fattorossi A, Sgambato A.

Biotechnol J. 2019 Jan;14(1):e1700716. doi: 10.1002/biot.201700716. Epub 2018 Jun 14. Review.

PMID:
29878510
23.

Controlled release of 18-β-glycyrrhetic acid by nanodelivery systems increases cytotoxicity on oral carcinoma cell line.

Cacciotti I, Chronopoulou L, Palocci C, Amalfitano A, Cantiani M, Cordaro M, Lajolo C, Callà C, Boninsegna A, Lucchetti D, Gallenzi P, Sgambato A, Nocca G, Arcovito A.

Nanotechnology. 2018 Jul 13;29(28):285101. doi: 10.1088/1361-6528/aabecc. Epub 2018 Apr 17.

PMID:
29664420
24.

J-ALEX trial will crown alectinib as the standard choice for anaplastic lymphoma kinase positive untreated non-small cell lung cancer patients?

Gridelli C, Casaluce F, Sgambato A, Palazzolo G, Maione P.

J Thorac Dis. 2018 Jan;10(1):106-108. doi: 10.21037/jtd.2017.12.76. No abstract available.

25.

Palladium nanoparticle effects on endocrine reproductive system of female rats.

Leso V, Fontana L, Marinaccio A, Leopold K, Fanali C, Lucchetti D, Sgambato A, Iavicoli I.

Hum Exp Toxicol. 2018 Oct;37(10):1069-1079. doi: 10.1177/0960327118756722. Epub 2018 Feb 6.

PMID:
29405765
26.

Second-Line Treatment Options in Non-Small-Cell Lung Cancer: Report From an International Experts Panel Meeting of the Italian Association of Thoracic Oncology.

Gridelli C, Baas P, Barlesi F, Ciardiello F, Crinò L, Felip E, Gadgeel S, Papadimitrakopoulou V, Paz-Ares L, Planchard D, Perol M, Hanna N, Sgambato A, Casaluce F, de Marinis F.

Clin Lung Cancer. 2018 Jul;19(4):301-314. doi: 10.1016/j.cllc.2017.12.010. Epub 2017 Dec 22. Review.

PMID:
29396237
27.

Targeted therapies in non-small cell lung cancer: a focus on ALK/ROS1 tyrosine kinase inhibitors.

Sgambato A, Casaluce F, Maione P, Gridelli C.

Expert Rev Anticancer Ther. 2018 Jan;18(1):71-80. doi: 10.1080/14737140.2018.1412260. Epub 2017 Dec 6. Review.

PMID:
29187012
28.

Soft tissue adhesion patterns over Trevira tube on modular endoprosthesis for malignant bone tumours: an in vitro study.

D’Adamio S, Cazzato G, Ziranu A, Sgambato A, Rosa MA, Maccauro G.

J Biol Regul Homeost Agents. 2017 Oct-Dec,;31(4 suppl 1):37-42.

PMID:
29181955
29.

Selumetinib for the treatment of non-small cell lung cancer.

Casaluce F, Sgambato A, Maione P, Sacco PC, Santabarbara G, Gridelli C.

Expert Opin Investig Drugs. 2017 Aug;26(8):973-984. doi: 10.1080/13543784.2017.1351543. Epub 2017 Jul 12. Review.

PMID:
28675058
30.

Differentiation Affects the Release of Exosomes from Colon Cancer Cells and Their Ability to Modulate the Behavior of Recipient Cells.

Lucchetti D, Calapà F, Palmieri V, Fanali C, Carbone F, Papa A, De Maria R, De Spirito M, Sgambato A.

Am J Pathol. 2017 Jul;187(7):1633-1647. doi: 10.1016/j.ajpath.2017.03.015. Epub 2017 Jun 12.

31.

In vitro evaluation of the potential toxic effects of palladium nanoparticles on fibroblasts and lung epithelial cells.

Iavicoli I, Farina M, Fontana L, Lucchetti D, Leso V, Fanali C, Cufino V, Boninsegna A, Leopold K, Schindl R, Brucker D, Sgambato A.

Toxicol In Vitro. 2017 Aug;42:191-199. doi: 10.1016/j.tiv.2017.04.024. Epub 2017 May 1.

PMID:
28473196
32.

Muscle Microdialysis to Investigate Inflammatory Biomarkers in Facioscapulohumeral Muscular Dystrophy.

Tasca G, Monforte M, Corbi M, Granata G, Lucchetti D, Sgambato A, Ricci E.

Mol Neurobiol. 2018 Apr;55(4):2959-2966. doi: 10.1007/s12035-017-0563-x. Epub 2017 Apr 29.

PMID:
28456937
33.

Subchronic exposure to palladium nanoparticles affects serum levels of cytokines in female Wistar rats.

Iavicoli I, Fontana L, Leso V, Corbi M, Marinaccio A, Leopold K, Schindl R, Lucchetti D, Calapà F, Sgambato A.

Hum Exp Toxicol. 2018 Mar;37(3):309-320. doi: 10.1177/0960327117702952. Epub 2017 Apr 7.

PMID:
28387145
34.

The safety of second-line treatment options for non-small cell lung cancer.

Rossi A, Maione P, Santabarbara G, Sacco PC, Casaluce F, Sgambato A, Barzelloni ML, Palazzolo G, Gridelli C.

Expert Opin Drug Saf. 2017 Apr;16(4):471-479. doi: 10.1080/14740338.2017.1297795. Epub 2017 Mar 1. Review.

PMID:
28276858
35.

The role of checkpoint inhibitors immunotherapy in advanced non-small cell lung cancer in the elderly.

Sgambato A, Casaluce F, Gridelli C.

Expert Opin Biol Ther. 2017 May;17(5):565-571. doi: 10.1080/14712598.2017.1294157. Epub 2017 Feb 20. Review.

PMID:
28276698
36.

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

Genovese G, Carugo A, Tepper J, Robinson FS, Li L, Svelto M, Nezi L, Corti D, Minelli R, Pettazzoni P, Gutschner T, Wu CC, Seth S, Akdemir KC, Leo E, Amin S, Molin MD, Ying H, Kwong LN, Colla S, Takahashi K, Ghosh P, Giuliani V, Muller F, Dey P, Jiang S, Garvey J, Liu CG, Zhang J, Heffernan TP, Toniatti C, Fleming JB, Goggins MG, Wood LD, Sgambato A, Agaimy A, Maitra A, Roberts CW, Wang H, Viale A, DePinho RA, Draetta GF, Chin L.

Nature. 2017 Feb 16;542(7641):362-366. doi: 10.1038/nature21064. Epub 2017 Feb 8.

PMID:
28178232
37.

Developments in pharmacotherapy for treating metastatic non-small cell lung cancer.

Rossi A, Sacco PC, Santabarbara G, Sgambato A, Casaluce F, Palazzolo G, Maione P, Gridelli C.

Expert Opin Pharmacother. 2017 Feb;18(2):151-163. doi: 10.1080/14656566.2017.1280460. Epub 2017 Jan 20. Review.

PMID:
28067062
38.

Infliximab does not increase colonic cancer risk associated to murine chronic colitis.

Lopetuso LR, Petito V, Zinicola T, Graziani C, Gerardi V, Arena V, Caristo ME, Poscia A, Cammarota G, Papa A, Cufino V, Sgambato A, Gasbarrini A, Scaldaferri F.

World J Gastroenterol. 2016 Nov 28;22(44):9727-9733.

39.

The Role of the Antiangiogenetic Ramucirumab in the Treatment of Advanced Non Small Cell Lung Cancer.

Maione P, Sgambato A, Casaluce F, Sacco PC, Santabarbara G, Rossi A, Gridelli C.

Curr Med Chem. 2017;24(1):3-13. doi: 10.2174/0929867324666161118125103. Review.

PMID:
27855622
40.

Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering.

Sgambato A, Cipolla L, Russo L.

Gels. 2016 Oct 14;2(4). pii: E28. doi: 10.3390/gels2040028. Review.

41.

Immunotherapy of non-small cell lung cancer: report from an international experts panel meeting of the Italian association of thoracic oncology.

Gridelli C, Ascierto PA, Barberis MC, Felip E, Garon EB, O'brien M, Senan S, Casaluce F, Sgambato A, Papadimitrakopoulou V, De Marinis F.

Expert Opin Biol Ther. 2016 Dec;16(12):1479-1489. Epub 2016 Sep 21.

PMID:
27650132
42.

Immunopathological characterization of cryptoglandular anal fistula: a pilot study investigating its pathogenesis.

Ratto C, Litta F, Lucchetti D, Parello A, Boninsegna A, Arena V, Donisi L, Calapà F, Sgambato A.

Colorectal Dis. 2016 Dec;18(12):O436-O444. doi: 10.1111/codi.13527.

PMID:
27649390
43.

HLA-Cw6 allele, NFkB1 and NFkBIA polymorphisms play no role in predicting response to etanercept in psoriatic patients.

Caldarola G, Sgambato A, Fanali C, Moretta G, Farina M, Lucchetti D, Peris K, De Simone C.

Pharmacogenet Genomics. 2016 Sep;26(9):423-7. doi: 10.1097/FPC.0000000000000233.

PMID:
27348478
44.

Toll-Like Receptor 2 Mediates In Vivo Pro- and Anti-inflammatory Effects of Mycobacterium Tuberculosis and Modulates Autoimmune Encephalomyelitis.

Piermattei A, Migliara G, Di Sante G, Foti M, Hayrabedyan SB, Papagna A, Geloso MC, Corbi M, Valentini M, Sgambato A, Delogu G, Constantin G, Ria F.

Front Immunol. 2016 May 24;7:191. doi: 10.3389/fimmu.2016.00191. eCollection 2016.

45.

Treatment of limited-stage small cell lung cancer in the elderly, chemotherapy vs. sequential chemoradiotherapy vs. concurrent chemoradiotherapy: that's the question.

Gridelli C, Casaluce F, Sgambato A, Monaco F, Guida C.

Transl Lung Cancer Res. 2016 Apr;5(2):150-4. doi: 10.21037/tlcr.2016.03.03.

46.

Resistance to Crizotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) with ALK Rearrangement: Mechanisms, Treatment Strategies and New Targeted Therapies.

Casaluce F, Sgambato A, Sacco PC, Palazzolo G, Maione P, Rossi A, Ciardiello F, Gridelli C.

Curr Clin Pharmacol. 2016;11(2):77-87. Review.

PMID:
27138017
47.

Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.

Guillem-Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, Grande R, Alberti S, Arena V, Cirillo M, Patrono C, FitzGerald GA, Steinhilber D, Sgambato A, Patrignani P.

Oncotarget. 2016 May 31;7(22):32462-77. doi: 10.18632/oncotarget.8655.

48.

Overcoming Resistance to EGFR Inhibitors in NSCLC.

Maione P, Sacco PC, Casaluce F, Sgambato A, Santabarbara G, Rossi A, Gridelli C.

Rev Recent Clin Trials. 2016;11(2):99-105. Review.

PMID:
27028971
49.

IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer.

Buoncervello M, Romagnoli G, Buccarelli M, Fragale A, Toschi E, Parlato S, Lucchetti D, Macchia D, Spada M, Canini I, Sanchez M, Falchi M, Musella M, Biffoni M, Belardelli F, Capone I, Sgambato A, Vitiani LR, Gabriele L.

Oncotarget. 2016 May 3;7(18):26361-73. doi: 10.18632/oncotarget.8379.

50.

Optimal drugs for second-line treatment of patients with small-cell lung cancer.

Rossi A, Sacco PC, Sgambato A, Casaluce F, Santabarbara G, Palazzolo G, Maione P, Gridelli C.

Expert Opin Pharmacother. 2016;17(7):969-76. doi: 10.1517/14656566.2016.1154539. Epub 2016 Feb 29. Review.

PMID:
26878692

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