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Items: 40


HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy.

Triulzi T, Forte L, Regondi V, Di Modica M, Ghirelli C, Carcangiu ML, Sfondrini L, Balsari A, Tagliabue E.

Oncoimmunology. 2018 Sep 21;8(1):e1512942. doi: 10.1080/2162402X.2018.1512942. eCollection 2019.


Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit.

Triulzi T, Regondi V, De Cecco L, Cappelletti MR, Di Modica M, Paolini B, Lollini PL, Di Cosimo S, Sfondrini L, Generali D, Tagliabue E.

Br J Cancer. 2018 Dec;119(12):1487-1494. doi: 10.1038/s41416-018-0318-0. Epub 2018 Nov 27.


Modulation of Pulmonary Microbiota by Antibiotic or Probiotic Aerosol Therapy: A Strategy to Promote Immunosurveillance against Lung Metastases.

Le Noci V, Guglielmetti S, Arioli S, Camisaschi C, Bianchi F, Sommariva M, Storti C, Triulzi T, Castelli C, Balsari A, Tagliabue E, Sfondrini L.

Cell Rep. 2018 Sep 25;24(13):3528-3538. doi: 10.1016/j.celrep.2018.08.090.


Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade.

Lo Russo G, Moro M, Sommariva M, Cancila V, Boeri M, Centonze G, Ferro S, Ganzinelli M, Gasparini P, Huber V, Milione M, Porcu L, Proto C, Pruneri G, Signorelli D, Sangaletti S, Sfondrini L, Storti C, Tassi E, Bardelli A, Marsoni S, Torri V, Tripodo C, Colombo MP, Anichini A, Rivoltini L, Balsari A, Sozzi G, Garassino MC.

Clin Cancer Res. 2019 Feb 1;25(3):989-999. doi: 10.1158/1078-0432.CCR-18-1390. Epub 2018 Sep 11.


The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer.

Forte L, Turdo F, Ghirelli C, Aiello P, Casalini P, Iorio MV, D'Ippolito E, Gasparini P, Agresti R, Belmonte B, Sozzi G, Sfondrini L, Tagliabue E, Campiglio M, Bianchi F.

BMC Cancer. 2018 May 23;18(1):586. doi: 10.1186/s12885-018-4500-9.


Exploiting poly(I:C) to induce cancer cell apoptosis.

Bianchi F, Pretto S, Tagliabue E, Balsari A, Sfondrini L.

Cancer Biol Ther. 2017 Oct 3;18(10):747-756. doi: 10.1080/15384047.2017.1373220. Epub 2017 Sep 7. Review.


Three months of Western diet induces small intestinal mucosa alteration in TLR KO mice.

Sardi C, Luchini P, Emanuelli A, Giannoni A, Martini E, Manara LM, Sfondrini L, Kallikourdis M, Sommariva M, Rumio C.

Microsc Res Tech. 2017 Jun;80(6):563-569. doi: 10.1002/jemt.22831. Epub 2017 Jan 17.


Activation of NK cell cytotoxicity by aerosolized CpG-ODN/poly(I:C) against lung melanoma metastases is mediated by alveolar macrophages.

Sommariva M, Le Noci V, Storti C, Bianchi F, Tagliabue E, Balsari A, Sfondrini L.

Cell Immunol. 2017 Mar;313:52-58. doi: 10.1016/j.cellimm.2017.01.004. Epub 2017 Jan 5.


Reprogramming the lung microenvironment by inhaled immunotherapy fosters immune destruction of tumor.

Le Noci V, Sommariva M, Tortoreto M, Zaffaroni N, Campiglio M, Tagliabue E, Balsari A, Sfondrini L.

Oncoimmunology. 2016 Sep 20;5(11):e1234571. doi: 10.1080/2162402X.2016.1234571. eCollection 2016.


Expression and prognostic significance of the autoimmune regulator gene in breast cancer cells.

Bianchi F, Sommariva M, De Cecco L, Triulzi T, Romero-Cordoba S, Tagliabue E, Sfondrini L, Balsari A.

Cell Cycle. 2016 Dec;15(23):3220-3229. Epub 2016 Oct 18.


CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers.

Turdo F, Bianchi F, Gasparini P, Sandri M, Sasso M, De Cecco L, Forte L, Casalini P, Aiello P, Sfondrini L, Agresti R, Carcangiu ML, Plantamura I, Sozzi G, Tagliabue E, Campiglio M.

Oncotarget. 2016 Oct 25;7(43):69649-69665. doi: 10.18632/oncotarget.11935.


CpG-oligodeoxynucleotides exert remarkable antitumor activity against diffuse malignant peritoneal mesothelioma orthotopic xenografts.

De Cesare M, Sfondrini L, Pennati M, De Marco C, Motta V, Tagliabue E, Deraco M, Balsari A, Zaffaroni N.

J Transl Med. 2016 Jan 25;14:25. doi: 10.1186/s12967-016-0781-4.


Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition.

Di Modica M, Sfondrini L, Regondi V, Varchetta S, Oliviero B, Mariani G, Bianchi GV, Generali D, Balsari A, Triulzi T, Tagliabue E.

Oncotarget. 2016 Jan 5;7(1):255-65. doi: 10.18632/oncotarget.6353.


Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment.

Le Noci V, Tortoreto M, Gulino A, Storti C, Bianchi F, Zaffaroni N, Tripodo C, Tagliabue E, Balsari A, Sfondrini L.

Oncoimmunology. 2015 May 27;4(10):e1040214. eCollection 2015 Oct.


Aerosol Delivery in the Treatment of Lung Cancer.

Storti C, Le Noci V, Sommariva M, Tagliabue E, Balsari A, Sfondrini L.

Curr Cancer Drug Targets. 2015;15(7):604-12. Review.


Fhit Nuclear Import Following EGF Stimulation Sustains Proliferation of Breast Cancer Cells.

Bianchi F, Sasso M, Turdo F, Beretta GL, Casalini P, Ghirelli C, Sfondrini L, Ménard S, Tagliabue E, Campiglio M.

J Cell Physiol. 2015 Nov;230(11):2661-70. doi: 10.1002/jcp.24968.


Anti-tumor activity of CpG-ODN aerosol in mouse lung metastases.

Sfondrini L, Sommariva M, Tortoreto M, Meini A, Piconese S, Calvaruso M, Van Rooijen N, Bonecchi R, Zaffaroni N, Colombo MP, Tagliabue E, Balsari A.

Int J Cancer. 2013 Jul 15;133(2):383-93. doi: 10.1002/ijc.28028. Epub 2013 Feb 12.


Influence of fatty acid-free diet on mammary tumor development and growth rate in HER-2/Neu transgenic mice.

Rossini A, Zanobbio L, Sfondrini L, Cavalleri A, Secreto G, Morelli D, Palazzo M, Sommariva M, Tagliabue E, Rumio C, Balsari A.

J Cell Physiol. 2013 Jan;228(1):242-9. doi: 10.1002/jcp.24130.


TLR9 agonists oppositely modulate DNA repair genes in tumor versus immune cells and enhance chemotherapy effects.

Sommariva M, De Cecco L, De Cesare M, Sfondrini L, Ménard S, Melani C, Delia D, Zaffaroni N, Pratesi G, Uva V, Tagliabue E, Balsari A.

Cancer Res. 2011 Oct 15;71(20):6382-90. doi: 10.1158/0008-5472.CAN-11-1285. Epub 2011 Aug 30.


Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands.

Rumio C, Sommariva M, Sfondrini L, Palazzo M, Morelli D, Viganò L, De Cecco L, Tagliabue E, Balsari A.

J Cell Physiol. 2012 Mar;227(3):1107-13. doi: 10.1002/jcp.22830.


Influence of lignans depletion on murine mammary gland morphology.

Rossini A, Zanobbio L, Palazzo M, Sfondrini L, Morelli D, Tagliabue E, Balsari A, Rumio C.

Nutr Cancer. 2010;62(2):237-42. doi: 10.1080/01635580903305284.


Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN.

De Cesare M, Sfondrini L, Campiglio M, Sommariva M, Bianchi F, Perego P, van Rooijen N, Supino R, Rumio C, Zunino F, Pratesi G, Tagliabue E, Balsari A.

J Immunother. 2010 Jan;33(1):8-15. doi: 10.1097/CJI.0b013e3181affaa7.


Critical role of TLR9 in acute graft-versus-host disease.

Calcaterra C, Sfondrini L, Rossini A, Sommariva M, Rumio C, Ménard S, Balsari A.

J Immunol. 2008 Nov 1;181(9):6132-9.


Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4.

Gariboldi S, Palazzo M, Zanobbio L, Selleri S, Sommariva M, Sfondrini L, Cavicchini S, Balsari A, Rumio C.

J Immunol. 2008 Aug 1;181(3):2103-10.


Influence of antibiotic treatment on breast carcinoma development in proto-neu transgenic mice.

Rossini A, Rumio C, Sfondrini L, Tagliabue E, Morelli D, Miceli R, Mariani L, Palazzo M, Ménard S, Balsari A.

Cancer Res. 2006 Jun 15;66(12):6219-24.


Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer.

Sfondrini L, Rossini A, Besusso D, Merlo A, Tagliabue E, Mènard S, Balsari A.

J Immunol. 2006 Jun 1;176(11):6624-30.


Antibody response after vaccination with antigen-pulsed dendritic cells.

Battaini F, Besusso D, Sfondrini L, Rossini A, Morelli D, Tagliabue E, Menard S, Balsari A.

Int J Biol Markers. 2004 Jul-Sep;19(3):213-20.


Degranulation of paneth cells via toll-like receptor 9.

Rumio C, Besusso D, Palazzo M, Selleri S, Sfondrini L, Dubini F, Ménard S, Balsari A.

Am J Pathol. 2004 Aug;165(2):373-81.


Combination of a CpG-oligodeoxynucleotide and a topoisomerase I inhibitor in the therapy of human tumour xenografts.

Balsari A, Tortoreto M, Besusso D, Petrangolini G, Sfondrini L, Maggi R, Ménard S, Pratesi G.

Eur J Cancer. 2004 May;40(8):1275-81.


CpG-Oligodeoxynucleotides activate tyrosinase-related protein 2-specific T lymphocytes but do not lead to a protective tumor-specific memory response.

Sfondrini L, Besusso D, Bronte V, Macino B, Rossini A, Colombo MP, Ménard S, Balsari A.

Cancer Immunol Immunother. 2004 Aug;53(8):697-704. Epub 2004 Mar 18.


Innate immunity in breast carcinoma.

Sfondrini L, Balsari A, Ménard S.

Endocr Relat Cancer. 2003 Jun;10(2):301-8. Review.


Prevention of spontaneous mammary adenocarcinoma in HER-2/neu transgenic mice by foreign DNA.

Sfondrini L, Besusso D, Rumio C, Rodolfo M, Ménard S, Balsari A.

FASEB J. 2002 Nov;16(13):1749-54.


Absence of the CD1 molecule up-regulates antitumor activity induced by CpG oligodeoxynucleotides in mice.

Sfondrini L, Besusso D, Zoia MT, Rodolfo M, Invernizzi AM, Taniguchi M, Nakayama T, Colombo MP, Ménard S, Balsari A.

J Immunol. 2002 Jul 1;169(1):151-8.


Topical administration of a doxorubicin-specific monoclonal antibody prevents drug-induced mouth apoptosis in mice.

Balsari A, Rumio C, Morelli D, Sfondrini L, Nardini E, Barajon I, Ménard S.

Br J Cancer. 2001 Dec 14;85(12):1964-7.


High level antibody response to retrovirus-associated but not to melanocyte lineage-specific antigens in mice protected against B16 melanoma.

Sfondrini L, Morelli D, Bodini A, Colnaghi MI, Ménard S, Balsari A.

Int J Cancer. 1999 Sep 24;83(1):107-12.


Segregation of type 1 cytokine production in human peripheral blood lymphocytes: phenotypic differences between IFN-gamma and IL-2-producing cells in the CD8+ T cell subset.

Caruso A, Licenziati S, Morelli D, Fiorentini S, Ricotta D, Malacarne F, Sfondrini L, Balsari A.

Eur J Immunol. 1998 Nov;28(11):3630-8.


Evaluation of the balance between angiogenic and antiangiogenic circulating factors in patients with breast and gastrointestinal cancers.

Morelli D, Lazzerini D, Cazzaniga S, Squicciarini P, Bignami P, Maier JA, Sfondrini L, Ménard S, Colnaghi MI, Balsari A.

Clin Cancer Res. 1998 May;4(5):1221-5.


Anti-tumor immunity induced by murine melanoma cells transduced with the Mycobacterium tuberculosis gene encoding the 38-kDa antigen.

Sfondrini L, Morelli D, Ménard S, Maier J, Singh M, Melani C, Terrazzini N, Colombo M, Colnaghi M, Balsari A.

Gene Ther. 1998 Feb;5(2):247-52.


Apoptosis of hair follicle cells during doxorubicin-induced alopecia in rats.

Cece R, Cazzaniga S, Morelli D, Sfondrini L, Bignotto M, Ménard S, Colnaghi MI, Balsari A.

Lab Invest. 1996 Oct;75(4):601-9.


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