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Items: 46


Interleukin-8 Expression is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer.

Maynard JP, Ertunc O, Kulac I, Baena Del Valle JA, De Marzo AM, Sfanos KS.

Mol Cancer Res. 2019 Oct 11. pii: molcanres.0595.2019. doi: 10.1158/1541-7786.MCR-19-0595. [Epub ahead of print]


Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis.

Porter CM, Haffner MC, Kulac I, Maynard JP, Baena-Del Valle JA, Isaacs WB, Yegnasubramanian S, De Marzo AM, Sfanos KS.

Am J Pathol. 2019 Sep 6. pii: S0002-9440(19)30698-4. doi: 10.1016/j.ajpath.2019.07.016. [Epub ahead of print]


Inflammation-associated pathologies in a case of prostate schistosomiasis: Implications for a causal role in prostate carcinogenesis.

Peiffer LB, Poynton SL, Ernst SE, Hicks JL, De Marzo AM, Sfanos KS.

Prostate. 2019 Aug;79(11):1316-1325. doi: 10.1002/pros.23841. Epub 2019 Jun 18.


A Prospective Study of the Urinary and Gastrointestinal Microbiome in Prepubertal Males.

Kassiri B, Shrestha E, Kasprenski M, Antonescu C, Florea LD, Sfanos KS, Wang MH.

Urology. 2019 Sep;131:204-210. doi: 10.1016/j.urology.2019.05.031. Epub 2019 Jun 10.


TP53 missense mutation is associated with increased tumor-infiltrating T cells in primary prostate cancer.

Kaur HB, Lu J, Guedes LB, Maldonado L, Reitz L, Barber JR, De Marzo AM, Tomlins SA, Sfanos KS, Eisenberger M, Schaeffer EM, Joshu CE, Lotan TL.

Hum Pathol. 2019 May;87:95-102. doi: 10.1016/j.humpath.2019.02.006. Epub 2019 Mar 6.


If this is true, what does it imply? How end-user antibody validation facilitates insights into biology and disease.

Sfanos KS, Yegnasubramanian S, Nelson WG, Lotan TL, Kulac I, Hicks JL, Zheng Q, Bieberich CJ, Haffner MC, De Marzo AM.

Asian J Urol. 2019 Jan;6(1):10-25. doi: 10.1016/j.ajur.2018.11.006. Epub 2018 Dec 12. Review.


IBD as a risk factor for prostate cancer: what is the link?

Sfanos KS, Joshu CE.

Nat Rev Urol. 2019 May;16(5):271-272. doi: 10.1038/s41585-019-0157-7. No abstract available.


The Microbiome and Genitourinary Cancer: A Collaborative Review.

Markowski MC, Boorjian SA, Burton JP, Hahn NM, Ingersoll MA, Maleki Vareki S, Pal SK, Sfanos KS.

Eur Urol. 2019 Apr;75(4):637-646. doi: 10.1016/j.eururo.2018.12.043. Epub 2019 Jan 15. Review.


A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth.

Yu SH, Maynard JP, Vaghasia AM, De Marzo AM, Drake CG, Sfanos KS.

Prostate. 2019 Feb;79(2):215-222. doi: 10.1002/pros.23726. Epub 2018 Oct 21.


Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities.

Trabzonlu L, Kulac I, Zheng Q, Hicks JL, Haffner MC, Nelson WG, Sfanos KS, Ertunc O, Lotan TL, Heaphy CM, Meeker AK, Yegnasubramanian S, De Marzo AM.

Cold Spring Harb Perspect Med. 2019 Apr 1;9(4). pii: a030403. doi: 10.1101/cshperspect.a030403. Review.


Corpora amylacea in prostatectomy tissue and associations with molecular, histological, and lifestyle factors.

DuPre NC, Flavin R, Sfanos KS, Unger RH, To S, Gazeeva E, Fiorentino M, De Marzo AM, Rider JR, Mucci LA; Transdisciplinary Prostate Cancer Partnership(ToPCaP).

Prostate. 2018 Nov;78(15):1172-1180. doi: 10.1002/pros.23692. Epub 2018 Jul 15.


Phage Therapy in Prostatitis: Recent Prospects.

Górski A, Jończyk-Matysiak E, Łusiak-Szelachowska M, Międzybrodzki R, Weber-Dąbrowska B, Borysowski J, Letkiewicz S, Bagińska N, Sfanos KS.

Front Microbiol. 2018 Jun 29;9:1434. doi: 10.3389/fmicb.2018.01434. eCollection 2018. Review.


Compositional differences in gastrointestinal microbiota in prostate cancer patients treated with androgen axis-targeted therapies.

Sfanos KS, Markowski MC, Peiffer LB, Ernst SE, White JR, Pienta KJ, Antonarakis ES, Ross AE.

Prostate Cancer Prostatic Dis. 2018 Nov;21(4):539-548. doi: 10.1038/s41391-018-0061-x. Epub 2018 Jul 9.


Association of tumor-infiltrating T-cell density with molecular subtype, racial ancestry and clinical outcomes in prostate cancer.

Kaur HB, Guedes LB, Lu J, Maldonado L, Reitz L, Barber JR, De Marzo AM, Tosoian JJ, Tomlins SA, Schaeffer EM, Joshu CE, Sfanos KS, Lotan TL.

Mod Pathol. 2018 Oct;31(10):1539-1552. doi: 10.1038/s41379-018-0083-x. Epub 2018 May 30.


The microbiome in prostate inflammation and prostate cancer.

Porter CM, Shrestha E, Peiffer LB, Sfanos KS.

Prostate Cancer Prostatic Dis. 2018 Sep;21(3):345-354. doi: 10.1038/s41391-018-0041-1. Epub 2018 May 23. Review.


Targeting Toll-like Receptors in Cancer Prevention.

Sfanos KS.

Cancer Prev Res (Phila). 2018 May;11(5):251-254. doi: 10.1158/1940-6207.CAPR-18-0079. Epub 2018 Apr 16.


Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides.

Baena-Del Valle JA, Zheng Q, Hicks JL, Fedor H, Trock BJ, Morrissey C, Corey E, Cornish TC, Sfanos KS, De Marzo AM.

Am J Clin Pathol. 2017 Nov 2;148(5):398-415. doi: 10.1093/ajcp/aqx094.


The inflammatory microenvironment and microbiome in prostate cancer development.

Sfanos KS, Yegnasubramanian S, Nelson WG, De Marzo AM.

Nat Rev Urol. 2018 Jan;15(1):11-24. doi: 10.1038/nrurol.2017.167. Epub 2017 Oct 31. Review.


Profiling the Urinary Microbiome in Men with Positive versus Negative Biopsies for Prostate Cancer.

Shrestha E, White JR, Yu SH, Kulac I, Ertunc O, De Marzo AM, Yegnasubramanian S, Mangold LA, Partin AW, Sfanos KS.

J Urol. 2018 Jan;199(1):161-171. doi: 10.1016/j.juro.2017.08.001. Epub 2017 Aug 7.


Low Intratumoral Mast Cells Are Associated With a Higher Risk of Prostate Cancer Recurrence.

Hempel HA, Cuka NS, Kulac I, Barber JR, Cornish TC, Platz EA, De Marzo AM, Sfanos KS.

Prostate. 2017 Mar;77(4):412-424. doi: 10.1002/pros.23280. Epub 2016 Nov 21.


Beyond Seed and Soil: Understanding and Targeting Metastatic Prostate Cancer; Report From the 2016 Coffey-Holden Prostate Cancer Academy Meeting.

Miyahira AK, Roychowdhury S, Goswami S, Ippolito JE, Priceman SJ, Pritchard CC, Sfanos KS, Subudhi SK, Simons JW, Pienta KJ, Soule HR.

Prostate. 2017 Feb;77(2):123-144. doi: 10.1002/pros.23260. Epub 2016 Sep 28. Review.


A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells.

Yu SH, Zheng Q, Esopi D, Macgregor-Das A, Luo J, Antonarakis ES, Drake CG, Vessella R, Morrissey C, De Marzo AM, Sfanos KS.

Cancer Immunol Res. 2015 Oct;3(10):1175-84. doi: 10.1158/2326-6066.CIR-15-0013. Epub 2015 Jun 5.


Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)-Induced Cancer at Multiple Sites.

Sfanos KS, Canene-Adams K, Hempel H, Yu SH, Simons BW, Schaeffer AJ, Schaeffer EM, Nelson WG, De Marzo AM.

Cancer Prev Res (Phila). 2015 Aug;8(8):683-92. doi: 10.1158/1940-6207.CAPR-15-0090. Epub 2015 May 19.


Infections and inflammation in prostate cancer.

Sfanos KS, Isaacs WB, De Marzo AM.

Am J Clin Exp Urol. 2013 Dec 25;1(1):3-11.


The role of inflammation in prostate cancer.

Sfanos KS, Hempel HA, De Marzo AM.

Adv Exp Med Biol. 2014;816:153-81. doi: 10.1007/978-3-0348-0837-8_7. Review.


MSMB variation and prostate cancer risk: clues towards a possible fungal etiology.

Sutcliffe S, De Marzo AM, Sfanos KS, Laurence M.

Prostate. 2014 May;74(6):569-78. doi: 10.1002/pros.22778. Epub 2014 Jan 24. Review.


Draft Genome Sequences of Two Strains of Propionibacterium acnes Isolated from Radical Prostatectomy Specimens.

Mak TN, Sfanos KS, Brüggemann H.

Genome Announc. 2013 Dec 19;1(6). pii: e01071-13. doi: 10.1128/genomeA.01071-13.


Dietary chemoprevention of PhIP induced carcinogenesis in male Fischer 344 rats with tomato and broccoli.

Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM.

PLoS One. 2013 Nov 27;8(11):e79842. doi: 10.1371/journal.pone.0079842. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/1ac6412e-619f-4575-8b63-f5e16bd3252b. PLoS One. 2014;9(1). doi:10.1371/annotation/3fd9703c-a6d9-4715-9c93-cf5279ea4fa6.


Biobanking of derivatives from radical retropubic and robot-assisted laparoscopic prostatectomy tissues as part of the prostate cancer biorepository network.

Darshan M, Zheng Q, Fedor HL, Wyhs N, Yegnasubramanian S, Lee P, Melamed J, Netto GJ, Trock BJ, De Marzo AM, Sfanos KS.

Prostate. 2014 Jan;74(1):61-9. doi: 10.1002/pros.22730. Epub 2013 Sep 21.


Comparative genomics reveals distinct host-interacting traits of three major human-associated propionibacteria.

Mak TN, Schmid M, Brzuszkiewicz E, Zeng G, Meyer R, Sfanos KS, Brinkmann V, Meyer TF, Brüggemann H.

BMC Genomics. 2013 Sep 22;14:640. doi: 10.1186/1471-2164-14-640.


Deciphering the intracellular fate of Propionibacterium acnes in macrophages.

Fischer N, Mak TN, Shinohara DB, Sfanos KS, Meyer TF, Brüggemann H.

Biomed Res Int. 2013;2013:603046. doi: 10.1155/2013/603046. Epub 2013 Jun 5.


Infection of Xenotransplanted Human Cell Lines by Murine Retroviruses: A Lesson Brought Back to Light by XMRV.

Hempel HA, Burns KH, De Marzo AM, Sfanos KS.

Front Oncol. 2013 Jun 17;3:156. doi: 10.3389/fonc.2013.00156. eCollection 2013.


A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes.

Shinohara DB, Vaghasia AM, Yu SH, Mak TN, Brüggemann H, Nelson WG, De Marzo AM, Yegnasubramanian S, Sfanos KS.

Prostate. 2013 Jun;73(9):1007-15. doi: 10.1002/pros.22648. Epub 2013 Feb 6.


Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens.

Mak TN, Yu SH, De Marzo AM, Brüggemann H, Sfanos KS.

Prostate. 2013 May;73(7):770-7. doi: 10.1002/pros.22621. Epub 2012 Nov 26.


Propionibacterium acnes host cell tropism contributes to vimentin-mediated invasion and induction of inflammation.

Mak TN, Fischer N, Laube B, Brinkmann V, Metruccio MM, Sfanos KS, Mollenkopf HJ, Meyer TF, Brüggemann H.

Cell Microbiol. 2012 Nov;14(11):1720-33. doi: 10.1111/j.1462-5822.2012.01833.x. Epub 2012 Jul 22.


XMRV and prostate cancer--a 'final' perspective.

Sfanos KS, Aloia AL, De Marzo AM, Rein A.

Nat Rev Urol. 2012 Jan 10;9(2):111-8. doi: 10.1038/nrurol.2011.225. Review.


Prostate cancer and inflammation: the evidence.

Sfanos KS, De Marzo AM.

Histopathology. 2012 Jan;60(1):199-215. doi: 10.1111/j.1365-2559.2011.04033.x. Review.


Identification of replication competent murine gammaretroviruses in commonly used prostate cancer cell lines.

Sfanos KS, Aloia AL, Hicks JL, Esopi DM, Steranka JP, Shao W, Sanchez-Martinez S, Yegnasubramanian S, Burns KH, Rein A, De Marzo AM.

PLoS One. 2011;6(6):e20874. doi: 10.1371/journal.pone.0020874. Epub 2011 Jun 17.


The "infectious" nature of human prostate cancer: a cautionary note.

Sfanos KS, Isaacs JT.

Oncotarget. 2011 Apr;2(4):281-3. No abstract available.


XMRV: a new virus in prostate cancer?

Aloia AL, Sfanos KS, Isaacs WB, Zheng Q, Maldarelli F, De Marzo AM, Rein A.

Cancer Res. 2010 Dec 15;70(24):10028-33. doi: 10.1158/0008-5472.CAN-10-2837. Epub 2010 Oct 21.


Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+.

Sfanos KS, Bruno TC, Meeker AK, De Marzo AM, Isaacs WB, Drake CG.

Prostate. 2009 Nov 1;69(15):1694-703. doi: 10.1002/pros.21020.


Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer.

Sfanos KS, Wilson BA, De Marzo AM, Isaacs WB.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3443-8. doi: 10.1073/pnas.0810473106. Epub 2009 Feb 6.


An evaluation of PCR primer sets used for detection of Propionibacterium acnes in prostate tissue samples.

Sfanos KS, Isaacs WB.

Prostate. 2008 Oct 1;68(14):1492-5. doi: 10.1002/pros.20820.


Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing.

Sfanos KS, Bruno TC, Maris CH, Xu L, Thoburn CJ, DeMarzo AM, Meeker AK, Isaacs WB, Drake CG.

Clin Cancer Res. 2008 Jun 1;14(11):3254-61. doi: 10.1158/1078-0432.CCR-07-5164.


A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms.

Sfanos KS, Sauvageot J, Fedor HL, Dick JD, De Marzo AM, Isaacs WB.

Prostate. 2008 Feb 15;68(3):306-20. doi: 10.1002/pros.20680.


HBMMD: an enhanced database of the microorganisms associated with deeper water marine invertebrates.

Gunasekera AS, Sfanos KS, Harmody DK, Pomponi SA, McCarthy PJ, Lopez JV.

Appl Microbiol Biotechnol. 2005 Jan;66(4):373-6. Epub 2004 Nov 16. Review.


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