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Items: 1 to 50 of 88

1.

Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study.

Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, Colombara DV, Ikuta KS, Kissoon N, Finfer S, Fleischmann-Struzek C, Machado FR, Reinhart KK, Rowan K, Seymour CW, Watson RS, West TE, Marinho F, Hay SI, Lozano R, Lopez AD, Angus DC, Murray CJL, Naghavi M.

Lancet. 2020 Jan 18;395(10219):200-211. doi: 10.1016/S0140-6736(19)32989-7.

2.

Murine sepsis phenotypes and differential treatment effects in a randomized trial of prompt antibiotics and fluids.

Seymour CW, Kerti SJ, Lewis AJ, Kennedy J, Brant E, Griepentrog JE, Zhang X, Angus DC, Chang CH, Rosengart MR.

Crit Care. 2019 Nov 28;23(1):384. doi: 10.1186/s13054-019-2655-7.

3.

Identifying Sepsis Phenotypes-Reply.

Seymour CW, Angus DC.

JAMA. 2019 Oct 8;322(14):1417. doi: 10.1001/jama.2019.12595. No abstract available.

PMID:
31593269
4.

Patterns of Opioid Administration Among Opioid-Naive Inpatients and Associations With Postdischarge Opioid Use: A Cohort Study.

Donohue JM, Kennedy JN, Seymour CW, Girard TD, Lo-Ciganic WH, Kim CH, Marroquin OC, Moyo P, Chang CH, Angus DC.

Ann Intern Med. 2019 Jul 16;171(2):81-90. doi: 10.7326/M18-2864. Epub 2019 Jun 18.

5.

Association Between Intravenous Fluid Bolus and Biomarker Trajectory During Prehospital Care.

Brant EB, Kennedy J, Martin-Gill C, Jackson V, Peck Palmer OM, Callaway CW, Kahn JM, Yealy DM, Angus DC, Seymour CW.

Prehosp Emerg Care. 2019 Jul 1:1-8. doi: 10.1080/10903127.2019.1629134. [Epub ahead of print]

PMID:
31180262
6.

Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients.

Crouser ED, Parrillo JE, Seymour CW, Angus DC, Bicking K, Esguerra VG, Peck-Palmer OM, Magari RT, Julian MW, Kleven JM, Raj PJ, Procopio G, Careaga D, Tejidor L.

Crit Care Med. 2019 Aug;47(8):1018-1025. doi: 10.1097/CCM.0000000000003799.

7.

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.

Seymour CW, Kennedy JN, Wang S, Chang CH, Elliott CF, Xu Z, Berry S, Clermont G, Cooper G, Gomez H, Huang DT, Kellum JA, Mi Q, Opal SM, Talisa V, van der Poll T, Visweswaran S, Vodovotz Y, Weiss JC, Yealy DM, Yende S, Angus DC.

JAMA. 2019 May 28;321(20):2003-2017. doi: 10.1001/jama.2019.5791.

8.

Strategy to Identify Paramedic Transported Sepsis Cases in an Emergency Department Administrative Database.

Lane DJ, Blanchard IE, Cheskes S, Lazarenko G, Lin S, Morrison LJ, Saskin R, Seymour CW, Wunsch H, Scales DC.

Prehosp Emerg Care. 2020 Jan-Feb;24(1):23-31. doi: 10.1080/10903127.2019.1611978. Epub 2019 May 31.

PMID:
31046502
9.

Sepsis Surveillance Using Adult Sepsis Events Simplified eSOFA Criteria Versus Sepsis-3 Sequential Organ Failure Assessment Criteria.

Rhee C, Zhang Z, Kadri SS, Murphy DJ, Martin GS, Overton E, Seymour CW, Angus DC, Dantes R, Epstein L, Fram D, Schaaf R, Wang R, Klompas M; CDC Prevention Epicenters Program.

Crit Care Med. 2019 Mar;47(3):307-314. doi: 10.1097/CCM.0000000000003521.

PMID:
30768498
10.

Sepsis Bundles and Mortality Among Pediatric Patients-Reply.

Evans IVR, Angus DC, Seymour CW.

JAMA. 2018 Dec 4;320(21):2271-2272. doi: 10.1001/jama.2018.16751. No abstract available.

PMID:
30512096
11.

Validity of the qSOFA Score in Low- and Middle-Income Countries-Reply.

Rudd KE, Seymour CW, Angus DC.

JAMA. 2018 Nov 20;320(19):2039-2040. doi: 10.1001/jama.2018.14477. No abstract available.

PMID:
30458489
12.

Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons.

Rhee C, Jentzsch MS, Kadri SS, Seymour CW, Angus DC, Murphy DJ, Martin GS, Dantes RB, Epstein L, Fiore AE, Jernigan JA, Danner RL, Warren DK, Septimus EJ, Hickok J, Poland RE, Jin R, Fram D, Schaaf R, Wang R, Klompas M; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program.

Crit Care Med. 2019 Apr;47(4):493-500. doi: 10.1097/CCM.0000000000003554.

PMID:
30431493
13.

The global burden of sepsis: barriers and potential solutions.

Rudd KE, Kissoon N, Limmathurotsakul D, Bory S, Mutahunga B, Seymour CW, Angus DC, West TE.

Crit Care. 2018 Sep 23;22(1):232. doi: 10.1186/s13054-018-2157-z. Review.

14.

Mortality Changes Associated with Mandated Public Reporting for Sepsis. The Results of the New York State Initiative.

Levy MM, Gesten FC, Phillips GS, Terry KM, Seymour CW, Prescott HC, Friedrich M, Iwashyna TJ, Osborn T, Lemeshow S.

Am J Respir Crit Care Med. 2018 Dec 1;198(11):1406-1412. doi: 10.1164/rccm.201712-2545OC.

15.

Evaluation of Repeated Quick Sepsis-Related Organ Failure Assessment Measurements Among Patients With Suspected Infection.

Kievlan DR, Zhang LA, Chang CH, Angus DC, Seymour CW.

Crit Care Med. 2018 Dec;46(12):1906-1913. doi: 10.1097/CCM.0000000000003360.

16.

Comparing the validity of different ICD coding abstraction strategies for sepsis case identification in German claims data.

Fleischmann-Struzek C, Thomas-Rüddel DO, Schettler A, Schwarzkopf D, Stacke A, Seymour CW, Haas C, Dennler U, Reinhart K.

PLoS One. 2018 Jul 30;13(7):e0198847. doi: 10.1371/journal.pone.0198847. eCollection 2018.

17.

Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis.

Evans IVR, Phillips GS, Alpern ER, Angus DC, Friedrich ME, Kissoon N, Lemeshow S, Levy MM, Parker MM, Terry KM, Watson RS, Weiss SL, Zimmerman J, Seymour CW.

JAMA. 2018 Jul 24;320(4):358-367. doi: 10.1001/jama.2018.9071.

18.

Arguing for Adaptive Clinical Trials in Sepsis.

Talisa VB, Yende S, Seymour CW, Angus DC.

Front Immunol. 2018 Jun 28;9:1502. doi: 10.3389/fimmu.2018.01502. eCollection 2018. Review.

19.

Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries.

Rudd KE, Seymour CW, Aluisio AR, Augustin ME, Bagenda DS, Beane A, Byiringiro JC, Chang CH, Colas LN, Day NPJ, De Silva AP, Dondorp AM, Dünser MW, Faiz MA, Grant DS, Haniffa R, Van Hao N, Kennedy JN, Levine AC, Limmathurotsakul D, Mohanty S, Nosten F, Papali A, Patterson AJ, Schieffelin JS, Shaffer JG, Thuy DB, Thwaites CL, Urayeneza O, White NJ, West TE, Angus DC; Sepsis Assessment and Identification in Low Resource Settings (SAILORS) Collaboration.

JAMA. 2018 Jun 5;319(21):2202-2211. doi: 10.1001/jama.2018.6229.

20.

Children with Chronic Disease Bear the Highest Burden of Pediatric Sepsis.

Prout AJ, Talisa VB, Carcillo JA, Mayr FB, Angus DC, Seymour CW, Chang CH, Yende S.

J Pediatr. 2018 Aug;199:194-199.e1. doi: 10.1016/j.jpeds.2018.03.056. Epub 2018 May 9.

21.

Making Sepsis Molecular: Is There Enough Time for New Tests?

Seymour CW, Bernard G.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):832-833. doi: 10.1164/rccm.201804-0684ED. No abstract available.

22.

Reporting of Sepsis Cases for Performance Measurement Versus for Reimbursement in New York State.

Prescott HC, Cope TM, Gesten FC, Ledneva TA, Friedrich ME, Iwashyna TJ, Osborn TM, Seymour CW, Levy MM.

Crit Care Med. 2018 May;46(5):666-673. doi: 10.1097/CCM.0000000000003005.

23.

Prompt Administration of Antibiotics and Fluids in the Treatment of Sepsis: A Murine Trial.

Lewis AJ, Griepentrog JE, Zhang X, Angus DC, Seymour CW, Rosengart MR.

Crit Care Med. 2018 May;46(5):e426-e434. doi: 10.1097/CCM.0000000000003004.

24.

Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness.

Seymour CW, Gomez H, Chang CH, Clermont G, Kellum JA, Kennedy J, Yende S, Angus DC.

Crit Care. 2017 Oct 18;21(1):257. doi: 10.1186/s13054-017-1836-5. Review.

25.

Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014.

Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, Kadri SS, Angus DC, Danner RL, Fiore AE, Jernigan JA, Martin GS, Septimus E, Warren DK, Karcz A, Chan C, Menchaca JT, Wang R, Gruber S, Klompas M; CDC Prevention Epicenter Program.

JAMA. 2017 Oct 3;318(13):1241-1249. doi: 10.1001/jama.2017.13836.

26.

Epidemiology of Sepsis Among Adolescents at Community Hospital Emergency Departments: Implications for Rory's Regulations.

Evans IVR, Watson RS, Carcillo J, Angus DC, Seymour CW.

JAMA Pediatr. 2017 Oct 1;171(10):1011-1012. doi: 10.1001/jamapediatrics.2017.1915. No abstract available.

27.

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis.

Seymour CW, Gesten F, Prescott HC, Friedrich ME, Iwashyna TJ, Phillips GS, Lemeshow S, Osborn T, Terry KM, Levy MM.

N Engl J Med. 2017 Jun 8;376(23):2235-2244. doi: 10.1056/NEJMoa1703058. Epub 2017 May 21.

28.

Delays From First Medical Contact to Antibiotic Administration for Sepsis.

Seymour CW, Kahn JM, Martin-Gill C, Callaway CW, Yealy DM, Scales D, Angus DC.

Crit Care Med. 2017 May;45(5):759-765. doi: 10.1097/CCM.0000000000002264.

29.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.

Intensive Care Med. 2017 Mar;43(3):304-377. doi: 10.1007/s00134-017-4683-6. Epub 2017 Jan 18.

PMID:
28101605
30.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.

Crit Care Med. 2017 Mar;45(3):486-552. doi: 10.1097/CCM.0000000000002255.

PMID:
28098591
31.

Effects of Physician-targeted Pay for Performance on Use of Spontaneous Breathing Trials in Mechanically Ventilated Patients.

Barbash IJ, Pike F, Gunn SR, Seymour CW, Kahn JM.

Am J Respir Crit Care Med. 2017 Jul 1;196(1):56-63. doi: 10.1164/rccm.201607-1505OC.

32.

Hospital-Level Changes in Adult ICU Bed Supply in the United States.

Wallace DJ, Seymour CW, Kahn JM.

Crit Care Med. 2017 Jan;45(1):e67-e76.

33.

External validation of a prehospital risk score for critical illness.

Kievlan DR, Martin-Gill C, Kahn JM, Callaway CW, Yealy DM, Angus DC, Seymour CW.

Crit Care. 2016 Aug 11;20(1):255. doi: 10.1186/s13054-016-1408-0.

34.

Clinical Criteria to Identify Patients With Sepsis--Reply.

Seymour CW, Angus DC.

JAMA. 2016 Jul 26;316(4):454. doi: 10.1001/jama.2016.6413. No abstract available.

PMID:
27458955
35.

Current Murine Models of Sepsis.

Lewis AJ, Seymour CW, Rosengart MR.

Surg Infect (Larchmt). 2016 Aug;17(4):385-93. doi: 10.1089/sur.2016.021. Epub 2016 Jun 15. Review. No abstract available.

36.

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC.

JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.

37.

Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, Angus DC, Rubenfeld GD, Singer M; Sepsis Definitions Task Force.

JAMA. 2016 Feb 23;315(8):775-87. doi: 10.1001/jama.2016.0289. Review.

38.

Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, Deutschman CS, Escobar GJ, Angus DC.

JAMA. 2016 Feb 23;315(8):762-74. doi: 10.1001/jama.2016.0288. Erratum in: JAMA. 2016 May 24-31;315(20):2237.

39.

Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria.

Seymour CW, Coopersmith CM, Deutschman CS, Gesten F, Klompas M, Levy M, Martin GS, Osborn TM, Rhee C, Warren DK, Watson RS, Angus DC.

Crit Care Med. 2016 Mar;44(3):e122-30. doi: 10.1097/CCM.0000000000001724.

40.

A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria.

Angus DC, Seymour CW, Coopersmith CM, Deutschman CS, Klompas M, Levy MM, Martin GS, Osborn TM, Rhee C, Watson RS.

Crit Care Med. 2016 Mar;44(3):e113-21. doi: 10.1097/CCM.0000000000001730. Review.

41.

Use of Biotelemetry to Define Physiology-Based Deterioration Thresholds in a Murine Cecal Ligation and Puncture Model of Sepsis.

Lewis AJ, Yuan D, Zhang X, Angus DC, Rosengart MR, Seymour CW.

Crit Care Med. 2016 Jun;44(6):e420-31. doi: 10.1097/CCM.0000000000001615.

42.

Bedside Ultrasonography for Diagnosis of Septic Shock--Reply.

Seymour CW, Rosengart MR.

JAMA. 2016 Jan 5;315(1):89-90. doi: 10.1001/jama.2015.15073. No abstract available.

PMID:
26746467
43.

Septic Shock: Advances in Diagnosis and Treatment.

Seymour CW, Rosengart MR.

JAMA. 2015 Aug 18;314(7):708-17. doi: 10.1001/jama.2015.7885. Review. Erratum in: JAMA. 2015 Oct 6;314(13):1404.

44.

Accuracy of Prehospital Intravenous Fluid Volume Measurement by Emergency Medical Services.

Coppler PJ, Padmanabhan R, Martin-Gill C, Callaway CW, Yealy DM, Seymour CW.

Prehosp Emerg Care. 2016;20(1):125-31. doi: 10.3109/10903127.2015.1051681. Epub 2015 Aug 13.

45.

County-Level Effects of Prehospital Regionalization of Critically Ill Patients: A Simulation Study.

Seymour CW, Alotaik O, Wallace DJ, Elhabashy AE, Chhatwal J, Rea TD, Angus DC, Nichol G, Kahn JM.

Crit Care Med. 2015 Sep;43(9):1807-15. doi: 10.1097/CCM.0000000000001133.

46.

Critical care bed growth in the United States. A comparison of regional and national trends.

Wallace DJ, Angus DC, Seymour CW, Barnato AE, Kahn JM.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):410-6. doi: 10.1164/rccm.201409-1746OC.

47.

Effect of public reporting on intensive care unit discharge destination and outcomes.

Reineck LA, Le TQ, Seymour CW, Barnato AE, Angus DC, Kahn JM.

Ann Am Thorac Soc. 2015 Jan;12(1):57-63. doi: 10.1513/AnnalsATS.201407-342OC.

48.

Prehospital intravenous access and fluid resuscitation in severe sepsis: an observational cohort study.

Seymour CW, Cooke CR, Heckbert SR, Spertus JA, Callaway CW, Martin-Gill C, Yealy DM, Rea TD, Angus DC.

Crit Care. 2014 Sep 27;18(5):533. doi: 10.1186/s13054-014-0533-x.

49.

The burden of influenza-associated critical illness hospitalizations.

Ortiz JR, Neuzil KM, Shay DK, Rue TC, Neradilek MB, Zhou H, Seymour CW, Hooper LG, Cheng PY, Goss CH, Cooke CR.

Crit Care Med. 2014 Nov;42(11):2325-32. doi: 10.1097/CCM.0000000000000545.

50.

Hospital-level variation in ICU admission and critical care procedures for patients hospitalized for pulmonary embolism.

Admon AJ, Seymour CW, Gershengorn HB, Wunsch H, Cooke CR.

Chest. 2014 Dec;146(6):1452-1461. doi: 10.1378/chest.14-0059.

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