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Items: 1 to 50 of 188

1.

Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson's Disease.

Seyfried TN, Choi H, Chevalier A, Hogan D, Akgoc Z, Schneider JS.

ASN Neuro. 2018 Jan-Dec;10:1759091418781889. doi: 10.1177/1759091418781889.

2.

Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up.

Elsakka AMA, Bary MA, Abdelzaher E, Elnaggar M, Kalamian M, Mukherjee P, Seyfried TN.

Front Nutr. 2018 Mar 29;5:20. doi: 10.3389/fnut.2018.00020. eCollection 2018.

3.

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT.

Chen E, Kiebish MA, McDaniel J, Niedzwiecka K, Kucharczyk R, Ravasz D, Gao F, Narain NR, Sarangarajan R, Seyfried TN, Adam-Vizi V, Chinopoulos C.

Sci Rep. 2018 Apr 12;8(1):5915. doi: 10.1038/s41598-018-24305-2.

4.

Mycoplasma infection and hypoxia initiate succinate accumulation and release in the VM-M3 cancer cells.

Flores RE, Brown AK, Taus L, Khoury J, Glover F, Kami K, Sarangarajan R, Walshe TE, Narain NR, Kiebish MA, Shelton LM, Chinopoulos C, Seyfried TN.

Biochim Biophys Acta. 2018 Sep;1859(9):975-983. doi: 10.1016/j.bbabio.2018.03.012. Epub 2018 Mar 23.

PMID:
29580805
5.

Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer.

İyikesici MS, Slocum AK, Slocum A, Berkarda FB, Kalamian M, Seyfried TN.

Cureus. 2017 Jul 7;9(7):e1445. doi: 10.7759/cureus.1445.

6.

Quantification of metastatic load in a syngeneic murine model of metastasis.

Taus LJ, Flores RE, Seyfried TN.

Cancer Lett. 2017 Oct 1;405:56-62. doi: 10.1016/j.canlet.2017.07.011. Epub 2017 Jul 17.

PMID:
28729049
7.

Need for new review of article on ketogenic dietary regimes for cancer patients.

Klement RJ, Feinman RD, Gross EC, Champ CE, D'Agostino DP, Fine EJ, Kämmerer U, Poff A, Rho JM, Seyfried TN, Scheck AC.

Med Oncol. 2017 Jun;34(6):108. doi: 10.1007/s12032-017-0968-4. Epub 2017 Apr 27. No abstract available.

PMID:
28452037
8.

Ultrastructural characterization of the Mitochondria-associated membranes abnormalities in human astrocytomas: Functional and therapeutics implications.

Arismendi-Morillo G, Castellano-Ramírez A, Seyfried TN.

Ultrastruct Pathol. 2017 May-Jun;41(3):234-244. doi: 10.1080/01913123.2017.1300618. Epub 2017 Apr 4.

PMID:
28375672
10.

Press-pulse: a novel therapeutic strategy for the metabolic management of cancer.

Seyfried TN, Yu G, Maroon JC, D'Agostino DP.

Nutr Metab (Lond). 2017 Feb 23;14:19. doi: 10.1186/s12986-017-0178-2. eCollection 2017.

11.

The total and mitochondrial lipidome of Artemia franciscana encysted embryos.

Chen E, Kiebish MA, McDaniel J, Gao F, Narain NR, Sarangarajan R, Kacso G, Ravasz D, Seyfried TN, Adam-Vizi V, Chinopoulos C.

Biochim Biophys Acta. 2016 Nov;1861(11):1727-1735. doi: 10.1016/j.bbalip.2016.08.007. Epub 2016 Aug 16.

PMID:
27542539
12.

Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson's Disease.

Schneider JS, Seyfried TN, Choi HS, Kidd SK.

PLoS One. 2015 Dec 2;10(12):e0143351. doi: 10.1371/journal.pone.0143351. eCollection 2015.

13.

Influence of Serum and Hypoxia on Incorporation of [(14)C]-D-Glucose or [(14)C]-L-Glutamine into Lipids and Lactate in Murine Glioblastoma Cells.

Ta NL, Seyfried TN.

Lipids. 2015 Dec;50(12):1167-84. doi: 10.1007/s11745-015-4075-z. Epub 2015 Nov 5.

PMID:
26537505
14.

Cancer as a mitochondrial metabolic disease.

Seyfried TN.

Front Cell Dev Biol. 2015 Jul 7;3:43. doi: 10.3389/fcell.2015.00043. eCollection 2015.

15.

Bis(monoacylglycero)phosphate as a Macrophage Enriched Phospholipid.

Akgoc Z, Iosim S, Seyfried TN.

Lipids. 2015 Sep;50(9):907-12. doi: 10.1007/s11745-015-4045-5. Epub 2015 Jul 24.

PMID:
26205346
16.

Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.

Poff AM, Ward N, Seyfried TN, Arnold P, D'Agostino DP.

PLoS One. 2015 Jun 10;10(6):e0127407. doi: 10.1371/journal.pone.0127407. eCollection 2015.

17.

The role of metabolic therapy in treating glioblastoma multiforme.

Maroon JC, Seyfried TN, Donohue JP, Bost J.

Surg Neurol Int. 2015 Apr 16;6:61. doi: 10.4103/2152-7806.155259. eCollection 2015.

18.

AAV-mediated gene delivery in a feline model of Sandhoff disease corrects lysosomal storage in the central nervous system.

Rockwell HE, McCurdy VJ, Eaton SC, Wilson DU, Johnson AK, Randle AN, Bradbury AM, Gray-Edwards HL, Baker HJ, Hudson JA, Cox NR, Sena-Esteves M, Seyfried TN, Martin DR.

ASN Neuro. 2015 Apr 13;7(2). pii: 1759091415569908. doi: 10.1177/1759091415569908. Print 2015 Mar-Apr.

19.

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer.

Meidenbauer JJ, Mukherjee P, Seyfried TN.

Nutr Metab (Lond). 2015 Mar 11;12:12. doi: 10.1186/s12986-015-0009-2. eCollection 2015.

20.

Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses.

Akgoc Z, Sena-Esteves M, Martin DR, Han X, d'Azzo A, Seyfried TN.

J Lipid Res. 2015 May;56(5):1006-13. doi: 10.1194/jlr.M057851. Epub 2015 Mar 20.

21.

Myelin abnormalities in the optic and sciatic nerves in mice with GM1-gangliosidosis.

Heinecke KA, Luoma A, d'Azzo A, Kirschner DA, Seyfried TN.

ASN Neuro. 2015 Feb 18;7(1). pii: 1759091415568913. doi: 10.1177/1759091415568913. Print 2015 Jan-Feb.

22.

Widespread correction of central nervous system disease after intracranial gene therapy in a feline model of Sandhoff disease.

McCurdy VJ, Rockwell HE, Arthur JR, Bradbury AM, Johnson AK, Randle AN, Brunson BL, Hwang M, Gray-Edwards HL, Morrison NE, Johnson JA, Baker HJ, Cox NR, Seyfried TN, Sena-Esteves M, Martin DR.

Gene Ther. 2015 Feb;22(2):181-9. doi: 10.1038/gt.2014.108. Epub 2014 Dec 4.

PMID:
25474439
23.

Meal frequency and timing in health and disease.

Mattson MP, Allison DB, Fontana L, Harvie M, Longo VD, Malaisse WJ, Mosley M, Notterpek L, Ravussin E, Scheer FA, Seyfried TN, Varady KA, Panda S.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16647-53. doi: 10.1073/pnas.1413965111. Epub 2014 Nov 17.

24.

Ganglioside storage diseases: on the road to management.

Seyfried TN, Rockwell HE, Heinecke KA, Martin DR, Sena-Esteves M.

Adv Neurobiol. 2014;9:485-99. doi: 10.1007/978-1-4939-1154-7_22.

PMID:
25151393
25.

Metabolic therapy: a new paradigm for managing malignant brain cancer.

Seyfried TN, Flores R, Poff AM, D'Agostino DP, Mukherjee P.

Cancer Lett. 2015 Jan 28;356(2 Pt A):289-300. doi: 10.1016/j.canlet.2014.07.015. Epub 2014 Jul 25. Review.

PMID:
25069036
26.

Ketone strong: emerging evidence for a therapeutic role of ketone bodies in neurological and neurodegenerative diseases.

Seyfried TN.

J Lipid Res. 2014 Sep;55(9):1815-7. doi: 10.1194/jlr.E052944. Epub 2014 Jul 11. No abstract available.

27.

Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice.

Mantis JG, Meidenbauer JJ, Zimick NC, Centeno NA, Seyfried TN.

Epilepsy Res. 2014 Sep;108(7):1137-44. doi: 10.1016/j.eplepsyres.2014.05.010. Epub 2014 Jun 2.

PMID:
24938543
28.

Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice.

Meidenbauer JJ, Ta N, Seyfried TN.

Nutr Metab (Lond). 2014 May 22;11:23. doi: 10.1186/1743-7075-11-23. eCollection 2014.

29.

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer.

Poff AM, Ari C, Arnold P, Seyfried TN, D'Agostino DP.

Int J Cancer. 2014 Oct 1;135(7):1711-20. doi: 10.1002/ijc.28809. Epub 2014 May 14.

30.

Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation.

Dufort FJ, Gumina MR, Ta NL, Tao Y, Heyse SA, Scott DA, Richardson AD, Seyfried TN, Chiles TC.

J Biol Chem. 2014 Mar 7;289(10):7011-24. doi: 10.1074/jbc.M114.551051. Epub 2014 Jan 27.

31.

Cancer as a metabolic disease: implications for novel therapeutics.

Seyfried TN, Flores RE, Poff AM, D'Agostino DP.

Carcinogenesis. 2014 Mar;35(3):515-27. doi: 10.1093/carcin/bgt480. Epub 2013 Dec 16. Review.

32.

Autosomal dominant inheritance of brain cardiolipin fatty acid abnormality in VM/DK mice: association with hypoxic-induced cognitive insensitivity.

Ta NL, Jia X, Kiebish M, Seyfried TN.

Lipids. 2014 Jan;49(1):113-7. doi: 10.1007/s11745-013-3857-4. Epub 2013 Nov 16.

PMID:
24243001
33.

A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.

Ahmed SS, Li H, Cao C, Sikoglu EM, Denninger AR, Su Q, Eaton S, Liso Navarro AA, Xie J, Szucs S, Zhang H, Moore C, Kirschner DA, Seyfried TN, Flotte TR, Matalon R, Gao G.

Mol Ther. 2013 Dec;21(12):2136-47. doi: 10.1038/mt.2013.138. Epub 2013 Jul 2.

34.

The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.

Poff AM, Ari C, Seyfried TN, D'Agostino DP.

PLoS One. 2013 Jun 5;8(6):e65522. doi: 10.1371/journal.pone.0065522. Print 2013.

35.

Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy.

Bradbury AM, Cochran JN, McCurdy VJ, Johnson AK, Brunson BL, Gray-Edwards H, Leroy SG, Hwang M, Randle AN, Jackson LS, Morrison NE, Baek RC, Seyfried TN, Cheng SH, Cox NR, Baker HJ, Cachón-González MB, Cox TM, Sena-Esteves M, Martin DR.

Mol Ther. 2013 Jul;21(7):1306-15. doi: 10.1038/mt.2013.86. Epub 2013 May 21.

36.

Ethylenedioxy-PIP2 oxalate reduces ganglioside storage in juvenile Sandhoff disease mice.

Arthur JR, Wilson MW, Larsen SD, Rockwell HE, Shayman JA, Seyfried TN.

Neurochem Res. 2013 Apr;38(4):866-75. doi: 10.1007/s11064-013-0992-5. Epub 2013 Feb 16.

PMID:
23417430
37.

On the origin of cancer metastasis.

Seyfried TN, Huysentruyt LC.

Crit Rev Oncog. 2013;18(1-2):43-73. Review.

38.

Therapeutic effects of stem cells and substrate reduction in juvenile Sandhoff mice.

Arthur JR, Lee JP, Snyder EY, Seyfried TN.

Neurochem Res. 2012 Jun;37(6):1335-43. doi: 10.1007/s11064-012-0718-0. Epub 2012 Feb 25.

PMID:
22367451
39.

Dietary restriction promotes vessel maturation in a mouse astrocytoma.

Urits I, Mukherjee P, Meidenbauer J, Seyfried TN.

J Oncol. 2012;2012:264039. doi: 10.1155/2012/264039. Epub 2011 Dec 27.

40.

Itaconic acid is a mammalian metabolite induced during macrophage activation.

Strelko CL, Lu W, Dufort FJ, Seyfried TN, Chiles TC, Rabinowitz JD, Roberts MF.

J Am Chem Soc. 2011 Oct 19;133(41):16386-9. doi: 10.1021/ja2070889. Epub 2011 Sep 27.

41.

Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer?

Seyfried TN, Marsh J, Shelton LM, Huysentruyt LC, Mukherjee P.

Epilepsy Res. 2012 Jul;100(3):310-26. doi: 10.1016/j.eplepsyres.2011.06.017. Epub 2011 Aug 31. Review.

42.

Hypothesis: are neoplastic macrophages/microglia present in glioblastoma multiforme?

Huysentruyt LC, Akgoc Z, Seyfried TN.

ASN Neuro. 2011 Sep 22;3(4). pii: e00064. doi: 10.1042/AN20110011. Review.

43.

A mathematical model for the determination of steady-state cardiolipin remodeling mechanisms using lipidomic data.

Zhang L, Bell RJ, Kiebish MA, Seyfried TN, Han X, Gross RW, Chuang JH.

PLoS One. 2011;6(6):e21170. doi: 10.1371/journal.pone.0021170. Epub 2011 Jun 10.

44.

Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain.

Arthur JR, Heinecke KA, Seyfried TN.

J Lipid Res. 2011 Jul;52(7):1345-51. doi: 10.1194/jlr.M012633. Epub 2011 Apr 20.

45.

Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma.

Mulrooney TJ, Marsh J, Urits I, Seyfried TN, Mukherjee P.

PLoS One. 2011 Mar 30;6(3):e18085. doi: 10.1371/journal.pone.0018085.

46.

Biography of Dr. Robert K. Yu. Preface.

Seyfried TN.

Neurochem Res. 2011 Sep;36(9):1575-7. doi: 10.1007/s11064-011-0445-y. Epub 2011 Mar 18. No abstract available.

PMID:
21416119
47.

Lipid composition of whole brain and cerebellum in Hurler syndrome (MPS IH) mice.

Heinecke KA, Peacock BN, Blazar BR, Tolar J, Seyfried TN.

Neurochem Res. 2011 Sep;36(9):1669-76. doi: 10.1007/s11064-011-0400-y. Epub 2011 Jan 21.

PMID:
21253856
48.

The EL mouse: a natural model of autism and epilepsy.

Meidenbauer JJ, Mantis JG, Seyfried TN.

Epilepsia. 2011 Feb;52(2):347-57. doi: 10.1111/j.1528-1167.2010.02898.x. Epub 2011 Jan 4.

49.

AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival.

Baek RC, Broekman ML, Leroy SG, Tierney LA, Sandberg MA, d'Azzo A, Seyfried TN, Sena-Esteves M.

PLoS One. 2010 Oct 18;5(10):e13468. doi: 10.1371/journal.pone.0013468.

50.

Perspectives on the mesenchymal origin of metastatic cancer.

Huysentruyt LC, Seyfried TN.

Cancer Metastasis Rev. 2010 Dec;29(4):695-707. doi: 10.1007/s10555-010-9254-z. Review.

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