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Items: 1 to 50 of 93

1.

Malawian children with uncomplicated and cerebral malaria have decreased activated Vγ9Vδ2 γδ T cells which increase in convalescence.

Harawa V, Njie M, Keller T, Kim K, Jaworowski A, Seydel K, Rogerson SJ, Mandala W.

PLoS One. 2019 Oct 10;14(10):e0223410. doi: 10.1371/journal.pone.0223410. eCollection 2019.

2.

Diffusion-Weighted MR Imaging in a Prospective Cohort of Children with Cerebral Malaria Offers Insights into Pathophysiology and Prognosis.

Moghaddam SM, Birbeck GL, Taylor TE, Seydel KB, Kampondeni SD, Potchen MJ.

AJNR Am J Neuroradiol. 2019 Sep;40(9):1575-1580. doi: 10.3174/ajnr.A6159. Epub 2019 Aug 22.

PMID:
31439630
3.

Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria.

Barrera V, Haley MJ, Strangward P, Attree E, Kamiza S, Seydel KB, Taylor TE, Milner DA Jr, Craig AG, Couper KN.

Front Immunol. 2019 Jul 24;10:1747. doi: 10.3389/fimmu.2019.01747. eCollection 2019.

4.

Impact of Multiplicity of Plasmodium falciparum Infection on Clinical Disease in Malawi.

Earland D, Buchwald AG, Sixpence A, Chimenya M, Damson M, Seydel KB, Mathanga DP, Taylor TE, Laufer MK.

Am J Trop Med Hyg. 2019 Aug;101(2):412-415. doi: 10.4269/ajtmh.19-0093.

PMID:
31219007
5.

Naturally acquired immunity against immature Plasmodium falciparum gametocytes.

Dantzler KW, Ma S, Ngotho P, Stone WJR, Tao D, Rijpma S, De Niz M, Nilsson Bark SK, Jore MM, Raaijmakers TK, Early AM, Ubaida-Mohien C, Lemgruber L, Campo JJ, Teng AA, Le TQ, Walker CL, Hermand P, Deterre P, Davies DH, Felgner P, Morlais I, Wirth DF, Neafsey DE, Dinglasan RR, Laufer M, Huttenhower C, Seydel K, Taylor T, Bousema T, Marti M.

Sci Transl Med. 2019 Jun 5;11(495). pii: eaav3963. doi: 10.1126/scitranslmed.aav3963.

6.

Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1.

Bernabeu M, Gunnarsson C, Vishnyakova M, Howard CC, Nagao RJ, Avril M, Taylor TE, Seydel KB, Zheng Y, Smith JD.

MBio. 2019 May 28;10(3). pii: e00420-19. doi: 10.1128/mBio.00420-19.

7.

Meta-analysis of Plasmodium falciparum var Signatures Contributing to Severe Malaria in African Children and Indian Adults.

Duffy F, Bernabeu M, Babar PH, Kessler A, Wang CW, Vaz M, Chery L, Mandala WL, Rogerson SJ, Taylor TE, Seydel KB, Lavstsen T, Gomes E, Kim K, Lusingu J, Rathod PK, Aitchison JD, Smith JD.

MBio. 2019 Apr 30;10(2). pii: e00217-19. doi: 10.1128/mBio.00217-19.

8.

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection.

Fulakeza J, McNitt S, Vareta J, Saidi A, Mvula G, Taylor T, Mathanga DP, Small DS, Skarbinski J, Gutman JR, Seydel K.

Malar J. 2019 Mar 18;18(1):84. doi: 10.1186/s12936-019-2695-0.

9.

Neurodevelopmental Impairments 1 Year After Cerebral Malaria.

Langfitt JT, McDermott MP, Brim R, Mboma S, Potchen MJ, Kampondeni SD, Seydel KB, Semrud-Clikeman M, Taylor TE.

Pediatrics. 2019 Feb;143(2). pii: e20181026. doi: 10.1542/peds.2018-1026. Epub 2019 Jan 29.

PMID:
30696757
10.

Cerebral malaria is associated with differential cytoadherence to brain endothelial cells.

Storm J, Jespersen JS, Seydel KB, Szestak T, Mbewe M, Chisala NV, Phula P, Wang CW, Taylor TE, Moxon CA, Lavstsen T, Craig AG.

EMBO Mol Med. 2019 Feb;11(2). pii: e9164. doi: 10.15252/emmm.201809164.

11.

Malaria Modeling to Evaluate Treatment for Severe Disease.

Small D, Seydel K.

J Infect Dis. 2019 Apr 8;219(8):1176-1177. doi: 10.1093/infdis/jiy650. No abstract available.

PMID:
30517672
12.

Brain swelling is independent of peripheral plasma cytokine levels in Malawian children with cerebral malaria.

Harawa V, Njie M, Kessler A, Choko A, Kumwenda B, Kampondeni S, Potchen M, Kim K, Jaworowski A, Taylor T, Mandala W, Seydel K, Rogerson S.

Malar J. 2018 Nov 26;17(1):435. doi: 10.1186/s12936-018-2590-0.

13.

Association Between Age and Plasmodium falciparum Infection Dynamics.

Buchwald AG, Sorkin JD, Sixpence A, Chimenya M, Damson M, Wilson ML, Seydel K, Hochman S, Mathanga D, Taylor TE, Laufer MK.

Am J Epidemiol. 2019 Jan 1;188(1):169-176. doi: 10.1093/aje/kwy213.

PMID:
30252032
14.

Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow.

De Niz M, Meibalan E, Mejia P, Ma S, Brancucci NMB, Agop-Nersesian C, Mandt R, Ngotho P, Hughes KR, Waters AP, Huttenhower C, Mitchell JR, Martinelli R, Frischknecht F, Seydel KB, Taylor T, Milner D, Heussler VT, Marti M.

Sci Adv. 2018 May 23;4(5):eaat3775. doi: 10.1126/sciadv.aat3775. eCollection 2018 May.

15.

Clinical Implications of Asymptomatic Plasmodium falciparum Infections in Malawi.

Buchwald AG, Sixpence A, Chimenya M, Damson M, Sorkin JD, Wilson ML, Seydel K, Hochman S, Mathanga DP, Taylor TE, Laufer MK.

Clin Infect Dis. 2019 Jan 1;68(1):106-112. doi: 10.1093/cid/ciy427.

16.

Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes.

Postels DG, Wu X, Li C, Kaplan PW, Seydel KB, Taylor TE, Kousa YA, Idro R, Opoka R, John CC, Birbeck GL.

Malar J. 2018 May 22;17(1):208. doi: 10.1186/s12936-018-2355-9.

17.

Convalescent Plasmodium falciparum-specific seroreactivity does not correlate with paediatric malaria severity or Plasmodium antigen exposure.

Kessler A, Campo JJ, Harawa V, Mandala WL, Rogerson SJ, Mowrey WB, Seydel KB, Kim K.

Malar J. 2018 Apr 25;17(1):178. doi: 10.1186/s12936-018-2323-4.

18.

Type I Interferon Receptor Variants in Gene Regulatory Regions are Associated with Susceptibility to Cerebral Malaria in Malawi.

Feintuch CM, Tare A, Cusumano LR, Benayoun J, Ryu S, Sixpence A, Seydel K, Laufer M, Taylor T, Suh Y, Daily JP.

Am J Trop Med Hyg. 2018 Jun;98(6):1692-1698. doi: 10.4269/ajtmh.17-0887. Epub 2018 Apr 5.

19.

Simulation models predict that school-age children are responsible for most human-to-mosquito Plasmodium falciparum transmission in southern Malawi.

Coalson JE, Cohee LM, Buchwald AG, Nyambalo A, Kubale J, Seydel KB, Mathanga D, Taylor TE, Laufer MK, Wilson ML.

Malar J. 2018 Apr 3;17(1):147. doi: 10.1186/s12936-018-2295-4.

20.

Noninvasive measures of brain edema predict outcome in pediatric cerebral malaria.

Kampondeni SD, Birbeck GL, Seydel KB, Beare NA, Glover SJ, Hammond CA, Chilingulo CA, Taylor TE, Potchen MJ.

Surg Neurol Int. 2018 Mar 1;9:53. doi: 10.4103/sni.sni_297_17. eCollection 2018.

21.

Cerebrospinal fluid Plasmodium falciparum histidine-rich protein-2 in pediatric cerebral malaria.

Thakur KT, Vareta J, Carson KA, Kampondeni S, Potchen MJ, Birbeck GL, MacCormick I, Taylor T, Sullivan DJ, Seydel KB.

Malar J. 2018 Mar 23;17(1):125. doi: 10.1186/s12936-018-2272-y.

22.

1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria.

Potchen MJ, Kampondeni SD, Seydel KB, Haacke EM, Sinyangwe SS, Mwenechanya M, Glover SJ, Milner DA, Zeli E, Hammond CA, Utriainen D, Lishimpi K, Taylor TE, Birbeck GL.

Am J Trop Med Hyg. 2018 Feb;98(2):497-504. doi: 10.4269/ajtmh.17-0309. Epub 2018 Jan 4.

23.

Rapid Diagnostic Testing of Hospitalized Malawian Children Reveals Opportunities for Improved HIV Diagnosis and Treatment.

Madaline TF, Hochman SE, Seydel KB, Liomba A, Saidi A, Matebule G, Mowrey WB, O'Hare B, Milner DA Jr, Kim K.

Am J Trop Med Hyg. 2017 Dec;97(6):1929-1935. doi: 10.4269/ajtmh.17-0067. Epub 2017 Oct 12.

24.

Linking EPCR-Binding PfEMP1 to Brain Swelling in Pediatric Cerebral Malaria.

Kessler A, Dankwa S, Bernabeu M, Harawa V, Danziger SA, Duffy F, Kampondeni SD, Potchen MJ, Dambrauskas N, Vigdorovich V, Oliver BG, Hochman SE, Mowrey WB, MacCormick IJC, Mandala WL, Rogerson SJ, Sather DN, Aitchison JD, Taylor TE, Seydel KB, Smith JD, Kim K.

Cell Host Microbe. 2017 Nov 8;22(5):601-614.e5. doi: 10.1016/j.chom.2017.09.009. Epub 2017 Oct 26.

25.

Evidence from a natural experiment that malaria parasitemia is pathogenic in retinopathy-negative cerebral malaria.

Small DS, Taylor TE, Postels DG, Beare NA, Cheng J, MacCormick IJ, Seydel KB.

Elife. 2017 Jun 7;6. pii: e23699. doi: 10.7554/eLife.23699.

26.

Extensive alterations of blood metabolites in pediatric cerebral malaria.

Gupta S, Seydel K, Miranda-Roman MA, Feintuch CM, Saidi A, Kim RS, Birbeck GL, Taylor T, Daily JP.

PLoS One. 2017 Apr 20;12(4):e0175686. doi: 10.1371/journal.pone.0175686. eCollection 2017.

27.

Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.

Alkaitis MS, Wang H, Ikeda AK, Rowley CA, MacCormick IJ, Chertow JH, Billker O, Suffredini AF, Roberts DJ, Taylor TE, Seydel KB, Ackerman HC.

J Infect Dis. 2016 Dec 15;214(12):1840-1849.

28.

High prevalence of Plasmodium falciparum gametocyte infections in school-age children using molecular detection: patterns and predictors of risk from a cross-sectional study in southern Malawi.

Coalson JE, Walldorf JA, Cohee LM, Ismail MD, Mathanga D, Cordy RJ, Marti M, Taylor TE, Seydel KB, Laufer MK, Wilson ML.

Malar J. 2016 Nov 4;15(1):527.

29.

Safety of lumbar puncture in comatose children with clinical features of cerebral malaria.

Moxon CA, Zhao L, Li C, Seydel KB, MacCormick IJ, Diggle PJ, Mallewa M, Solomon T, Beare NA, Glover SJ, Harding SP, Lewallen S, Kampondeni S, Potchen MJ, Taylor TE, Postels DG.

Neurology. 2016 Nov 29;87(22):2355-2362. Epub 2016 Oct 28.

30.

HIV coinfection influences the inflammatory response but not the outcome of cerebral malaria in Malawian children.

Mbale EW, Moxon CA, Mukaka M, Chagomerana M, Glover S, Chisala N, Omar S, Molyneux M, Seydel K, Craig AG, Taylor T, Heyderman RS, Mallewa M.

J Infect. 2016 Sep;73(3):189-99. doi: 10.1016/j.jinf.2016.05.012. Epub 2016 Jun 14. Review.

31.

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients.

Joice R, Frantzreb C, Pradham A, Seydel KB, Kamiza S, Wirth DF, Duraisingh MT, Molyneux ME, Taylor TE, Marti M, Milner DA Jr.

Mod Pathol. 2016 Apr;29(4):381-90. doi: 10.1038/modpathol.2016.27. Epub 2016 Feb 26.

32.

Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children.

Feintuch CM, Saidi A, Seydel K, Chen G, Goldman-Yassen A, Mita-Mendoza NK, Kim RS, Frenette PS, Taylor T, Daily JP.

MBio. 2016 Feb 16;7(1):e01300-15. doi: 10.1128/mBio.01300-15.

33.

Author Correction for Hochman et al., Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection.

Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA Jr, Kim K.

MBio. 2016 Feb 2;7(1):e02068-15. doi: 10.1128/mBio.02068-15. No abstract available.

34.

Lipid metabolites of the phospholipase A2 pathway and inflammatory cytokines are associated with brain volume in paediatric cerebral malaria.

Pappa V, Seydel K, Gupta S, Feintuch CM, Potchen MJ, Kampondeni S, Goldman-Yassen A, Veenstra M, Lopez L, Kim RS, Berman JW, Taylor T, Daily JP.

Malar J. 2015 Dec 21;14:513. doi: 10.1186/s12936-015-1036-1.

35.

Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection.

Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA Jr, Kim K.

MBio. 2015 Sep 22;6(5):e01390-15. doi: 10.1128/mBio.01390-15. Erratum in: MBio. 2016;7(1):e02068-15.

36.

School-Age Children Are a Reservoir of Malaria Infection in Malawi.

Walldorf JA, Cohee LM, Coalson JE, Bauleni A, Nkanaunena K, Kapito-Tembo A, Seydel KB, Ali D, Mathanga D, Taylor TE, Valim C, Laufer MK.

PLoS One. 2015 Jul 24;10(7):e0134061. doi: 10.1371/journal.pone.0134061. eCollection 2015.

37.

Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding.

Moxon CA, Chisala NV, Mzikamanda R, MacCormick I, Harding S, Downey C, Molyneux M, Seydel KB, Taylor TE, Heyderman RS, Toh CH.

J Thromb Haemost. 2015 Sep;13(9):1653-64. doi: 10.1111/jth.13060. Epub 2015 Aug 27. Erratum in: J Thromb Haemost. 2016 Feb;14(2):415.

38.

Quantitative Assessment of Multiorgan Sequestration of Parasites in Fatal Pediatric Cerebral Malaria.

Milner DA Jr, Lee JJ, Frantzreb C, Whitten RO, Kamiza S, Carr RA, Pradham A, Factor RE, Playforth K, Liomba G, Dzamalala C, Seydel KB, Molyneux ME, Taylor TE.

J Infect Dis. 2015 Oct 15;212(8):1317-21. doi: 10.1093/infdis/jiv205. Epub 2015 Apr 7.

39.

Brain swelling and death in children with cerebral malaria.

Seydel KB, Kampondeni SD, Valim C, Potchen MJ, Milner DA, Muwalo FW, Birbeck GL, Bradley WG, Fox LL, Glover SJ, Hammond CA, Heyderman RS, Chilingulo CA, Molyneux ME, Taylor TE.

N Engl J Med. 2015 Mar 19;372(12):1126-37. doi: 10.1056/NEJMoa1400116.

40.

Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection.

Pelle KG, Oh K, Buchholz K, Narasimhan V, Joice R, Milner DA, Brancucci NM, Ma S, Voss TS, Ketman K, Seydel KB, Taylor TE, Barteneva NS, Huttenhower C, Marti M.

Genome Med. 2015 Feb 27;7(1):19. doi: 10.1186/s13073-015-0133-7. eCollection 2015.

41.

Plasmodium falciparum gene expression measured directly from tissue during human infection.

Van Tyne D, Tan Y, Daily JP, Kamiza S, Seydel K, Taylor T, Mesirov JP, Wirth DF, Milner DA Jr.

Genome Med. 2014 Nov 29;6(11):110. doi: 10.1186/s13073-014-0110-6. eCollection 2014.

42.

Subtle changes in Plasmodium falciparum infection complexity following enhanced intervention in Malawi.

Sisya TJ, Kamn'gona RM, Vareta JA, Fulakeza JM, Mukaka MF, Seydel KB, Laufer MK, Taylor TE, Nkhoma SC.

Acta Trop. 2015 Feb;142:108-14. doi: 10.1016/j.actatropica.2014.11.008. Epub 2014 Nov 25.

43.

Brain MRI of children with retinopathy-negative cerebral malaria.

Postels DG, Li C, Birbeck GL, Taylor TE, Seydel KB, Kampondeni SD, Glover SJ, Potchen MJ.

Am J Trop Med Hyg. 2014 Nov;91(5):943-9. doi: 10.4269/ajtmh.14-0216. Epub 2014 Sep 8.

44.

The systemic pathology of cerebral malaria in African children.

Milner DA Jr, Whitten RO, Kamiza S, Carr R, Liomba G, Dzamalala C, Seydel KB, Molyneux ME, Taylor TE.

Front Cell Infect Microbiol. 2014 Aug 21;4:104. doi: 10.3389/fcimb.2014.00104. eCollection 2014.

45.

Submicroscopic malaria infection during pregnancy and the impact of intermittent preventive treatment.

Cohee LM, Kalilani-Phiri L, Boudova S, Joshi S, Mukadam R, Seydel KB, Mawindo P, Thesing P, Kamiza S, Makwakwa K, Muehlenbachs A, Taylor TE, Laufer MK.

Malar J. 2014 Jul 15;13:274. doi: 10.1186/1475-2875-13-274.

46.

Plasmodium falciparum transmission stages accumulate in the human bone marrow.

Joice R, Nilsson SK, Montgomery J, Dankwa S, Egan E, Morahan B, Seydel KB, Bertuccini L, Alano P, Williamson KC, Duraisingh MT, Taylor TE, Milner DA, Marti M.

Sci Transl Med. 2014 Jul 9;6(244):244re5. doi: 10.1126/scitranslmed.3008882.

47.

Inferring developmental stage composition from gene expression in human malaria.

Joice R, Narasimhan V, Montgomery J, Sidhu AB, Oh K, Meyer E, Pierre-Louis W, Seydel K, Milner D, Williamson K, Wiegand R, Ndiaye D, Daily J, Wirth D, Taylor T, Huttenhower C, Marti M.

PLoS Comput Biol. 2013;9(12):e1003392. doi: 10.1371/journal.pcbi.1003392. Epub 2013 Dec 12.

48.

Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children.

Moxon CA, Chisala NV, Wassmer SC, Taylor TE, Seydel KB, Molyneux ME, Faragher B, Kennedy N, Toh CH, Craig AG, Heyderman RS.

J Infect Dis. 2014 Feb 15;209(4):610-5. doi: 10.1093/infdis/jit419. Epub 2013 Sep 17.

49.

NeuroInterp: a method for facilitating neuroimaging research on cerebral malaria.

Potchen MJ, Kampondeni SD, Ibrahim K, Bonner J, Seydel KB, Taylor TE, Birbeck GL.

Neurology. 2013 Aug 6;81(6):585-8. doi: 10.1212/WNL.0b013e31829e6ed5. Review. No abstract available.

50.

A histological method for quantifying Plasmodium falciparum in the brain in fatal paediatric cerebral malaria.

Milner DA Jr, Valim C, Carr RA, Chandak PB, Fosiko NG, Whitten R, Playforth KB, Seydel KB, Kamiza S, Molyneux ME, Taylor TE.

Malar J. 2013 Jun 7;12:191. doi: 10.1186/1475-2875-12-191.

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