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A Phase I/II Trial of Fairly Brief Androgen Suppression and Stereotactic Radiation Therapy for High-Risk Prostate Cancer (FASTR-2): Preliminary Results and Toxicity Analysis.

Callan L, Bauman G, Chen J, Lock M, Sexton T, D'Souza D, Rodrigues G.

Adv Radiat Oncol. 2019 Jul 16;4(4):668-673. doi: 10.1016/j.adro.2019.07.007. eCollection 2019 Oct-Dec.


Stereotactic image-guided neoadjuvant ablative single-dose radiation, then lumpectomy, for early breast cancer: the SIGNAL prospective single-arm trial of single-dose radiation therapy.

Guidolin K, Yaremko B, Lynn K, Gaede S, Kornecki A, Muscedere G, BenNachum I, Shmuilovich O, Mouawad M, Yu E, Sexton T, Gelman N, Moiseenko V, Brackstone M, Lock M.

Curr Oncol. 2019 Jun;26(3):e334-e340. doi: 10.3747/co.26.4479. Epub 2019 Jun 1.


Dissecting Gene Repression: Not Just Location, Location, Location.

Sexton T.

Trends Cell Biol. 2019 Aug;29(8):605-607. doi: 10.1016/j.tcb.2019.06.001. Epub 2019 Jun 21.


Optimization of Tissue Microarrays from Banked Human Formalin-Fixed Paraffin Embedded Tissues in the Cancer Research Setting.

Sexton T, Kucera GL, Levine EA, Watabe K, O'Neill SS.

Biopreserv Biobank. 2019 Oct;17(5):452-457. doi: 10.1089/bio.2019.0011. Epub 2019 Jun 13.


ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C.

Ben Zouari Y, Molitor AM, Sikorska N, Pancaldi V, Sexton T.

Genome Biol. 2019 May 22;20(1):102. doi: 10.1186/s13059-019-1706-3.


Early signatures of bleeding and mortality in patients on left ventricular assist device support: novel methods for personalized risk-stratification.

Shrout T, Sexton T, Vsevolozhskaya O, Guglin M, Shafii A, Smyth S.

Biomarkers. 2019 Jul;24(5):448-456. doi: 10.1080/1354750X.2019.1609089. Epub 2019 May 6.


Reducing the dose of gadolinium-based contrast agents for DCE-MRI guided SBRT: The effects on inter and intra observer variability for preoperative target volume delineation in early stage breast cancer patients.

Mouawad M, Biernaski H, Brackstone M, Lock M, Yaremko B, Sexton T, Yu E, Dinniwell RE, Lynn K, Hajdok G, Prato FS, Thompson RT, Gelman N, Gaede S.

Radiother Oncol. 2019 Feb;131:60-65. doi: 10.1016/j.radonc.2018.11.020. Epub 2018 Dec 29.


Changes in thromboinflammatory profiles across the generations of transcatheter aortic heart valves.

Sexton T, Alkhasova M, de Beer M, Lynch D, Smyth S.

J Thromb Thrombolysis. 2019 Feb;47(2):174-178. doi: 10.1007/s11239-018-1782-3.


Communication: Gas phase vibrational spectroscopy of the azide-water complex.

Kelly JT, Ellington TL, Sexton TM, Fortenberry RC, Tschumper GS, Asmis KR.

J Chem Phys. 2018 Nov 21;149(19):191101. doi: 10.1063/1.5053671.


Ticagrelor Reduces Thromboinflammatory Markers in Patients With Pneumonia.

Sexton TR, Zhang G, Macaulay TE, Callahan LA, Charnigo R, Vsevolozhskaya OA, Li Z, Smyth S.

JACC Basic Transl Sci. 2018 Aug 28;3(4):435-449. doi: 10.1016/j.jacbts.2018.05.005. eCollection 2018 Aug.


Letrozole concentration is associated with CYP2A6 variation but not with arthralgia in patients with breast cancer.

Borrie AE, Rose RV, Choi YH, Perera FE, Read N, Sexton T, Lock M, Vandenberg TA, Hahn K, Dinniwell R, Younus J, Logan D, Potvin K, Yaremko B, Yu E, Lenehan J, Welch S, Tyndale RF, Teft WA, Kim RB.

Breast Cancer Res Treat. 2018 Nov;172(2):371-379. doi: 10.1007/s10549-018-4910-z. Epub 2018 Aug 9.


Salmonella Contamination in Broiler Synovial Fluid: Are We Missing a Potential Reservoir?

Sexton TY, Geornaras I, Belk KE, Bunning M, Martin JN.

J Food Prot. 2018 Sep;81(9):1425-1431. doi: 10.4315/0362-028X.JFP-17-431.


Dissociation Energy of the H2O···HF Dimer.

Sexton TM, Howard JC, Tschumper GS.

J Phys Chem A. 2018 May 31;122(21):4902-4908. doi: 10.1021/acs.jpca.8b03397. Epub 2018 May 14.


Measuring Hospital Performance Using Mortality Rates: An Alternative to the RAMR.

Pitocco C, Sexton TR.

Int J Health Policy Manag. 2018 Apr 1;7(4):308-316. doi: 10.15171/ijhpm.2017.94.


TADs are 3D structural units of higher-order chromosome organization in Drosophila.

Szabo Q, Jost D, Chang JM, Cattoni DI, Papadopoulos GL, Bonev B, Sexton T, Gurgo J, Jacquier C, Nollmann M, Bantignies F, Cavalli G.

Sci Adv. 2018 Feb 28;4(2):eaar8082. doi: 10.1126/sciadv.aar8082. eCollection 2018 Feb.


High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens.

Chen R, McIntosh S, Hemby SE, Sun H, Sexton T, Martin TJ, Childers SR.

Neurosci Lett. 2018 Apr 3;671:133-139. doi: 10.1016/j.neulet.2018.02.026. Epub 2018 Feb 14.


Translational Implications of Platelets as Vascular First Responders.

Becker RC, Sexton T, Smyth SS.

Circ Res. 2018 Feb 2;122(3):506-522. doi: 10.1161/CIRCRESAHA.117.310939. Review.


Predictive Model Markup Language (PMML) Representation of Bayesian Networks: An Application in Manufacturing.

Nannapaneni S, Narayanan A, Ak R, Lechevalier D, Sexton T, Mahadevan S, Lee YT.

Smart Sustain Manuf Syst. 2018;2. doi: 10.1520/SSMS20180018.


Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.

Cattoni DI, Cardozo Gizzi AM, Georgieva M, Di Stefano M, Valeri A, Chamousset D, Houbron C, Déjardin S, Fiche JB, González I, Chang JM, Sexton T, Marti-Renom MA, Bantignies F, Cavalli G, Nollmann M.

Nat Commun. 2017 Nov 24;8(1):1753. doi: 10.1038/s41467-017-01962-x.


Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation.

Schauer T, Ghavi-Helm Y, Sexton T, Albig C, Regnard C, Cavalli G, Furlong EE, Becker PB.

EMBO Rep. 2017 Aug 9. pii: e201744292. doi: 10.15252/embr.201744292. [Epub ahead of print]


Supplementary data: Chemoradiotherapy in octogenarians as primary treatment for muscle-invasive bladder cancer.

McPherson VA, Rodrigues G, Bauman G, Winquist E, Chin J, Izawa J, Potvin K, Ernst S, Venkatesan V, Sexton T, Ahmad B, Power N.

Can Urol Assoc J. 2017 Jan-Feb;11(1-2):E64-E65. doi: 10.5489/cuaj.4476. Epub 2017 Feb 20. No abstract available.


Chemoradiotherapy in octogenarians as primary treatment for muscle-invasive bladder cancer.

McPherson VA, Rodrigues G, Bauman G, Winquist E, Chin J, Izawa J, Potvin K, Ernst S, Venkatesan V, Sexton T, Ahmad B, Power N.

Can Urol Assoc J. 2017 Jan-Feb;11(1-2):24-30. doi: 10.5489/cuaj.4008.


Acute Effects of Implantable Cardioverter-Defibrillator Shocks on Biomarkers of Myocardial Injury, Apoptosis, Heart Failure, and Systemic Inflammation.

Brewster J, Sexton T, Dhaliwal G, Charnigo R, Morales G, Parrott K, Darrat Y, Gurley J, Smyth S, Elayi CS.

Pacing Clin Electrophysiol. 2017 Apr;40(4):344-352. doi: 10.1111/pace.13037. Epub 2017 Mar 8.


Infant outcomes among women with Zika virus infection during pregnancy: results of a large prenatal Zika screening program.

Adhikari EH, Nelson DB, Johnson KA, Jacobs S, Rogers VL, Roberts SW, Sexton T, McIntire DD, Casey BM.

Am J Obstet Gynecol. 2017 Mar;216(3):292.e1-292.e8. doi: 10.1016/j.ajog.2017.01.018. Epub 2017 Jan 30.


A Reaction Valley Investigation of the Cycloaddition of 1,3-Dipoles with the Dipolarophiles Ethene and Acetylene: Solution of a Mechanistic Puzzle.

Sexton TM, Freindorf M, Kraka E, Cremer D.

J Phys Chem A. 2016 Oct 27;120(42):8400-8418. doi: 10.1021/acs.jpca.6b07975. Epub 2016 Oct 18.


A Single Institution Consensus on the Use of Sequential or Concurrent Hormonal Therapy for Breast Cancer Patients Receiving Radiation Therapy.

Cecchini MJ, Yu E, Yaremko BP, Boldt RG, Potvin K, Sexton T, D'Souza D, Brackstone M, Lock M.

Cureus. 2016 Apr 3;8(4):e555. doi: 10.7759/cureus.555.


Assessment of function and quality of life in a phase II multi-institutional clinical trial of fractionated simultaneous in-field boost radiotherapy for patients with 1-3 metastases.

Bauman G, Yartsev S, Roberge D, MacRae R, Roa W, Panet-Raymond V, Masucci L, Yaremko B, D'Souza D, Palma D, Sexton T, Yu E, Pantarotto JR, Ahmad B, Fisher B, Dar AR, Lambert C, Pond G, Stitt L, Tay KY, Rodrigues G.

J Neurooncol. 2016 Jul;128(3):431-6. doi: 10.1007/s11060-016-2128-7. Epub 2016 Apr 15.


Detecting Spatial Chromatin Organization by Chromosome Conformation Capture II: Genome-Wide Profiling by Hi-C.

Vietri Rudan M, Hadjur S, Sexton T.

Methods Mol Biol. 2017;1589:47-74. doi: 10.1007/7651_2015_261.


Extraordinary Mechanism of the Diels-Alder Reaction: Investigation of Stereochemistry, Charge Transfer, Charge Polarization, and Biradicaloid Formation.

Sexton T, Kraka E, Cremer D.

J Phys Chem A. 2016 Feb 25;120(7):1097-111. doi: 10.1021/acs.jpca.5b11493. Epub 2016 Feb 16.


Thromboinflammatory response and predictors of outcomes in patients undergoing transcatheter aortic valve replacement.

Sexton TR, Wallace EL, Chen A, Charnigo RJ, Reda HK, Ziada KM, Gurley JC, Smyth SS.

J Thromb Thrombolysis. 2016 Apr;41(3):384-93. doi: 10.1007/s11239-015-1326-z.


A New Method for Describing the Mechanism of a Chemical Reaction Based on the Unified Reaction Valley Approach.

Zou W, Sexton T, Kraka E, Freindorf M, Cremer D.

J Chem Theory Comput. 2016 Feb 9;12(2):650-63. doi: 10.1021/acs.jctc.5b01098. Epub 2016 Jan 26.


The Effectiveness of Functional Family Therapy in Reducing Adolescent Mental Health Risk and Family Adjustment Difficulties in an Irish Context.

Hartnett D, Carr A, Sexton T.

Fam Process. 2016 Jun;55(2):287-304. doi: 10.1111/famp.12195. Epub 2015 Nov 6.


Regional differences in mu and kappa opioid receptor G-protein activation in brain in male and female prairie voles.

Martin TJ, Sexton T, Kim SA, Severino AL, Peters CM, Young LJ, Childers SR.

Neuroscience. 2015 Dec 17;311:422-9. doi: 10.1016/j.neuroscience.2015.10.047. Epub 2015 Oct 30.


Respiratory motor function in individuals with centronuclear myopathies.

Smith BK, Renno MS, Green MM, Sexton TM, Lawson LA, Martin AD, Corti M, Byrne BJ.

Muscle Nerve. 2016 Feb;53(2):214-21. doi: 10.1002/mus.24899. Epub 2015 Dec 29. Erratum in: Muscle Nerve. 2016 Jun;53(6):1000.


Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains.

Ea V, Sexton T, Gostan T, Herviou L, Baudement MO, Zhang Y, Berlivet S, Le Lay-Taha MN, Cathala G, Lesne A, Victor JM, Fan Y, Cavalli G, Forné T.

BMC Genomics. 2015 Aug 15;16:607. doi: 10.1186/s12864-015-1786-8.


The significance of circulating tumor cells in prostate cancer patients undergoing adjuvant or salvage radiation therapy.

Lowes LE, Lock M, Rodrigues G, D'Souza D, Bauman G, Ahmad B, Venkatesan V, Allan AL, Sexton T.

Prostate Cancer Prostatic Dis. 2015 Dec;18(4):358-64. doi: 10.1038/pcan.2015.36. Epub 2015 Aug 4.


Type I intrinsically photosensitive retinal ganglion cells of early post-natal development correspond to the M4 subtype.

Sexton TJ, Bleckert A, Turner MH, Van Gelder RN.

Neural Dev. 2015 Jun 21;10:17. doi: 10.1186/s13064-015-0042-x.


G-Protein Coupled Receptor Kinase 2 Minimally Regulates Melanopsin Activity in Intrinsically Photosensitive Retinal Ganglion Cells.

Sexton TJ, Van Gelder RN.

PLoS One. 2015 Jun 12;10(6):e0128690. doi: 10.1371/journal.pone.0128690. eCollection 2015.


A Phase 1/2 Trial of Brief Androgen Suppression and Stereotactic Radiation Therapy (FASTR) for High-Risk Prostate Cancer.

Bauman G, Ferguson M, Lock M, Chen J, Ahmad B, Venkatesan VM, Sexton T, D'Souza D, Loblaw A, Warner A, Rodrigues G.

Int J Radiat Oncol Biol Phys. 2015 Jul 15;92(4):856-62. doi: 10.1016/j.ijrobp.2015.02.046. Epub 2015 Apr 30.


5-HT1B autoreceptors differentially modulate the expression of conditioned fear in a circuit-specific manner.

Liu Y, Kelly MA, Sexton TJ, Neumaier JF.

Neuroscience. 2015 Jul 9;298:436-47. doi: 10.1016/j.neuroscience.2015.04.032. Epub 2015 Apr 20.


The role of chromosome domains in shaping the functional genome.

Sexton T, Cavalli G.

Cell. 2015 Mar 12;160(6):1049-59. doi: 10.1016/j.cell.2015.02.040. Review.


Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding.

McIntosh S, Sexton T, Pattison LP, Childers SR, Hemby SE.

J Neuroimmune Pharmacol. 2015 Sep;10(3):493-505. doi: 10.1007/s11481-015-9594-0. Epub 2015 Mar 10.


Chronic baclofen desensitizes GABA(B)-mediated G-protein activation and stimulates phosphorylation of kinases in mesocorticolimbic rat brain.

Keegan BM, Beveridge TJ, Pezor JJ, Xiao R, Sexton T, Childers SR, Howlett AC.

Neuropharmacology. 2015 Aug;95:492-502. doi: 10.1016/j.neuropharm.2015.02.021. Epub 2015 Feb 25.


Chromosome folding: driver or passenger of epigenetic state?

Sexton T, Yaffe E.

Cold Spring Harb Perspect Biol. 2015 Feb 2;7(2):a018721. doi: 10.1101/cshperspect.a018721. Review.


The effect of rosuvastatin on platelet-leukocyte interactions in the setting of acute coronary syndrome.

Sexton TR, Wallace EL, Macaulay TE, Charnigo RJ, Evangelista V, Campbell CL, Bailey AL, Smyth SS.

J Am Coll Cardiol. 2015 Jan 27;65(3):306-7. doi: 10.1016/j.jacc.2014.10.047. No abstract available.


Evaluating the impact of a Canadian national anatomy and radiology contouring boot camp for radiation oncology residents.

Jaswal J, D'Souza L, Johnson M, Tay K, Fung K, Nichols A, Landis M, Leung E, Kassam Z, Willmore K, D'Souza D, Sexton T, Palma DA.

Int J Radiat Oncol Biol Phys. 2015 Mar 15;91(4):701-7. doi: 10.1016/j.ijrobp.2014.11.009. Epub 2015 Jan 13.


The effect of rosuvastatin on thromboinflammation in the setting of acute coronary syndrome.

Sexton TR, Wallace EL, Macaulay TE, Charnigo RJ, Evangelista V, Campbell CL, Bailey AL, Smyth SS.

J Thromb Thrombolysis. 2015 Feb;39(2):186-95. doi: 10.1007/s11239-014-1142-x.


Ultrasound surveillance for thyroid malignancies in survivors of childhood cancer following radiotherapy: a single institutional experience.

Li Z, Franklin J, Zelcer S, Sexton T, Husein M.

Thyroid. 2014 Dec;24(12):1796-805. doi: 10.1089/thy.2014.0132.


Cooperativity, specificity, and evolutionary stability of Polycomb targeting in Drosophila.

Schuettengruber B, Oded Elkayam N, Sexton T, Entrevan M, Stern S, Thomas A, Yaffe E, Parrinello H, Tanay A, Cavalli G.

Cell Rep. 2014 Oct 9;9(1):219-233. doi: 10.1016/j.celrep.2014.08.072. Epub 2014 Oct 2.

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