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Items: 45

1.

Oxysterol-related-binding-protein related Protein-2 (ORP2) regulates cortisol biosynthesis and cholesterol homeostasis.

Escajadillo T, Wang H, Li L, Li D, Sewer MB.

Mol Cell Endocrinol. 2016 May 15;427:73-85. doi: 10.1016/j.mce.2016.03.006. Epub 2016 Mar 16.

2.

p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation.

Lu JY, Sewer MB.

Mol Cell Biol. 2015 Apr;35(7):1223-37. doi: 10.1128/MCB.00993-14. Epub 2015 Jan 20.

3.

Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells.

Cai K, Lucki NC, Sewer MB.

Biochim Biophys Acta. 2014 Apr 4;1841(4):552-62. doi: 10.1016/j.bbalip.2013.12.005. Epub 2013 Dec 22.

5.

cAMP-stimulated transcription of DGKθ requires steroidogenic factor 1 and sterol regulatory element binding protein 1.

Cai K, Sewer MB.

J Lipid Res. 2013 Aug;54(8):2121-32. doi: 10.1194/jlr.M035634. Epub 2013 Apr 22.

6.

cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells.

Li D, Dammer EB, Lucki NC, Sewer MB.

Mol Biol Cell. 2013 Mar;24(6):848-57. doi: 10.1091/mbc.E12-08-0597. Epub 2013 Jan 16.

7.

Regulation of adrenocortical steroid hormone production by RhoA-diaphanous 1 signaling and the cytoskeleton.

Sewer MB, Li D.

Mol Cell Endocrinol. 2013 May 22;371(1-2):79-86. doi: 10.1016/j.mce.2012.11.014. Epub 2012 Nov 24. Review.

8.

Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor.

Lucki NC, Li D, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB.

Mol Cell Biol. 2012 Nov;32(21):4419-31. doi: 10.1128/MCB.00378-12. Epub 2012 Aug 27.

9.

Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc.

Li D, Dammer EB, Sewer MB.

Endocrinology. 2012 Jul;153(7):3258-68. doi: 10.1210/en.2011-2088. Epub 2012 May 14.

10.

Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression.

Lucki NC, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB.

Mol Endocrinol. 2012 Feb;26(2):228-43. doi: 10.1210/me.2011-1150. Epub 2012 Jan 19.

11.

Nuclear sphingolipid metabolism.

Lucki NC, Sewer MB.

Annu Rev Physiol. 2012;74:131-51. doi: 10.1146/annurev-physiol-020911-153321. Epub 2011 Sep 9. Review.

12.

Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells.

Lucki NC, Li D, Sewer MB.

Mol Cell Endocrinol. 2012 Jan 2;348(1):165-75. doi: 10.1016/j.mce.2011.08.003. Epub 2011 Aug 16.

13.

Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression.

Lucki NC, Sewer MB.

J Biol Chem. 2011 Jun 3;286(22):19399-409. doi: 10.1074/jbc.M110.195826. Epub 2011 Apr 14.

14.

RhoA and DIAPH1 mediate adrenocorticotropin-stimulated cortisol biosynthesis by regulating mitochondrial trafficking.

Li D, Sewer MB.

Endocrinology. 2010 Sep;151(9):4313-23. doi: 10.1210/en.2010-0044. Epub 2010 Jun 30.

15.

The interplay between bioactive sphingolipids and steroid hormones.

Lucki NC, Sewer MB.

Steroids. 2010 Jun;75(6):390-9. doi: 10.1016/j.steroids.2010.01.020. Epub 2010 Feb 4. Review.

16.

The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells.

Lucki N, Sewer MB.

Biochim Biophys Acta. 2009 Aug;1791(8):706-13. doi: 10.1016/j.bbalip.2009.03.005. Epub 2009 Mar 16.

17.

Complex assembly on the human CYP17 promoter.

Sewer MB, Jagarlapudi S.

Mol Cell Endocrinol. 2009 Mar 5;300(1-2):109-14. doi: 10.1016/j.mce.2008.10.006. Epub 2008 Oct 19. Review.

18.

Multiple roles for sphingolipids in steroid hormone biosynthesis.

Lucki NC, Sewer MB.

Subcell Biochem. 2008;49:387-412. doi: 10.1007/978-1-4020-8831-5_15. Review.

19.

Regulation of steroid hormone biosynthesis by the cytoskeleton.

Sewer MB, Li D.

Lipids. 2008 Dec;43(12):1109-15. doi: 10.1007/s11745-008-3221-2. Epub 2008 Aug 26. Review.

20.

Sphingosine-1-phosphate regulates the expression of the liver receptor homologue-1.

Hadizadeh S, King DN, Shah S, Sewer MB.

Mol Cell Endocrinol. 2008 Feb 13;283(1-2):104-13. doi: 10.1016/j.mce.2007.11.030. Epub 2007 Dec 5.

PMID:
18191017
21.

Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.

Dammer EB, Sewer MB.

J Biol Chem. 2008 Mar 14;283(11):6925-34. doi: 10.1074/jbc.M708432200. Epub 2008 Jan 9.

22.

Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal Cortex.

Sewer MB, Li D, Dammer EB, Jagarlapudi S, Lucki N.

Acta Chim Slov. 2008 Jan 1;55(1):53-57.

23.

Transcriptional regulation of adrenocortical steroidogenic gene expression.

Sewer MB, Dammer EB, Jagarlapudi S.

Drug Metab Rev. 2007;39(2-3):371-88. Review.

PMID:
17786627
24.

Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.

Li D, Urs AN, Allegood J, Leon A, Merrill AH Jr, Sewer MB.

Mol Cell Biol. 2007 Oct;27(19):6669-85. Epub 2007 Jul 30.

25.

Steroidogenic factor-1 is a sphingolipid binding protein.

Urs AN, Dammer E, Kelly S, Wang E, Merrill AH Jr, Sewer MB.

Mol Cell Endocrinol. 2007 Feb;265-266:174-8. Epub 2006 Dec 29. Review.

27.

Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1.

Urs AN, Dammer E, Sewer MB.

Endocrinology. 2006 Nov;147(11):5249-58. Epub 2006 Aug 3.

PMID:
16887917
28.
29.
30.

ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex.

Sewer MB, Waterman MR.

Microsc Res Tech. 2003 Jun 15;61(3):300-7. Review.

PMID:
12768545
31.

Transcriptional complexes at the CYP17 CRS.

Sewer MB, Waterman MR.

Endocr Res. 2002 Nov;28(4):551-8.

PMID:
12530662
32.

CAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells.

Sewer MB, Waterman MR.

J Biol Chem. 2003 Mar 7;278(10):8106-11. Epub 2002 Dec 27.

36.

Insights into the transcriptional regulation of steroidogenic enzymes and StAR.

Sewer MB, Waterman MR.

Rev Endocr Metab Disord. 2001 Aug;2(3):269-74. Review. No abstract available.

PMID:
11705132
37.
38.

Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent.

Barclay TB, Peters JM, Sewer MB, Ferrari L, Gonzalez FJ, Morgan ET.

J Pharmacol Exp Ther. 1999 Sep;290(3):1250-7.

PMID:
10454501
39.

Modulation of drug metabolism in infectious and inflammatory diseases.

Iber H, Sewer MB, Barclay TB, Mitchell SR, Li T, Morgan ET.

Drug Metab Rev. 1999 Feb;31(1):29-41. Review.

PMID:
10065364
40.

Physiological and pathophysiological regulation of cytochrome P450.

Morgan ET, Sewer MB, Iber H, Gonzalez FJ, Lee YH, Tukey RH, Okino S, Vu T, Chen YH, Sidhu JS, Omiecinski CJ.

Drug Metab Dispos. 1998 Dec;26(12):1232-40. Review.

PMID:
9860933
42.

Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene.

Sewer MB, Barclay TB, Morgan ET.

Mol Pharmacol. 1998 Aug;54(2):273-9.

PMID:
9687568
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