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Items: 1 to 50 of 136

1.

Germline selection shapes human mitochondrial DNA diversity.

Wei W, Tuna S, Keogh MJ, Smith KR, Aitman TJ, Beales PL, Bennett DL, Gale DP, Bitner-Glindzicz MAK, Black GC, Brennan P, Elliott P, Flinter FA, Floto RA, Houlden H, Irving M, Koziell A, Maher ER, Markus HS, Morrell NW, Newman WG, Roberts I, Sayer JA, Smith KGC, Taylor JC, Watkins H, Webster AR, Wilkie AOM, Williamson C; NIHR BioResource–Rare Diseases; 100,000 Genomes Project–Rare Diseases Pilot, Ashford S, Penkett CJ, Stirrups KE, Rendon A, Ouwehand WH, Bradley JR, Raymond FL, Caulfield M, Turro E, Chinnery PF.

Science. 2019 May 24;364(6442). pii: eaau6520. doi: 10.1126/science.aau6520. Epub 2019 May 23.

2.

The Distinguishing Clinical Features of Nonallergic Rhinitis Patients.

Hamizan AW, Azer M, Alvarado R, Earls P, Barham HP, Tattersall J, Rimmer J, Kalish L, Sewell WA, Harvey R.

Am J Rhinol Allergy. 2019 Sep;33(5):524-530. doi: 10.1177/1945892419850750. Epub 2019 May 20. No abstract available.

PMID:
31106562
3.

Nasal mucosal brushing as a diagnostic method for allergic rhinitis.

Hamizan A, Alvarado R, Rimmer J, Sewell WA, Barham HP, Kalish L, Harvey R.

Allergy Asthma Proc. 2019 May 1;40(3):167-172. doi: 10.2500/aap.2019.40.4209.

PMID:
31018891
4.

Turbinate-Specific IgE in Normal and Rhinitic Patients.

Hamizan AW, Rimmer J, Alvarado R, Sewell WA, Tatersall J, Barham HP, Kalish L, Harvey RJ.

Am J Rhinol Allergy. 2019 Mar;33(2):178-183. doi: 10.1177/1945892418825224. Epub 2019 Jan 18.

PMID:
30656948
5.

Atopy in chronic rhinosinusitis: impact on quality of life outcomes.

Ho J, Alvarado R, Rimmer J, Sewell WA, Harvey RJ.

Int Forum Allergy Rhinol. 2019 May;9(5):501-507. doi: 10.1002/alr.22272. Epub 2019 Jan 3.

PMID:
30604578
6.

Germline-activating mutations in PIK3CD compromise B cell development and function.

Avery DT, Kane A, Nguyen T, Lau A, Nguyen A, Lenthall H, Payne K, Shi W, Brigden H, French E, Bier J, Hermes JR, Zahra D, Sewell WA, Butt D, Elliott M, Boztug K, Meyts I, Choo S, Hsu P, Wong M, Berglund LJ, Gray P, O'Sullivan M, Cole T, Holland SM, Ma CS, Burkhart C, Corcoran LM, Phan TG, Brink R, Uzel G, Deenick EK, Tangye SG.

J Exp Med. 2018 Aug 6;215(8):2073-2095. doi: 10.1084/jem.20180010. Epub 2018 Jul 17.

7.

Systemic Predictors of Eosinophilic Chronic Rhinosinusitis.

Ho J, Hamizan AW, Alvarado R, Rimmer J, Sewell WA, Harvey RJ.

Am J Rhinol Allergy. 2018 Jul;32(4):252-257. doi: 10.1177/1945892418779451. Epub 2018 Jun 4.

PMID:
29862828
8.

CD200 is a useful diagnostic marker for identifying atypical chronic lymphocytic leukemia by flow cytometry.

Ting YS, Smith SABC, Brown DA, Dodds AJ, Fay KC, Ma DDF, Milliken S, Moore JJ, Sewell WA.

Int J Lab Hematol. 2018 May 27. doi: 10.1111/ijlh.12857. [Epub ahead of print]

PMID:
29806244
9.

Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency.

Deenick EK, Morey A, Danta M, Emmett L, Fay K, Gracie G, Ma CS, Macintosh R, Smith SABC, Sasson SC, Sewell WA, Cowley M, Tangye SG, Kelleher AD; CIRCA, Phan TG.

J Clin Immunol. 2018 Feb;38(2):159-162. doi: 10.1007/s10875-018-0477-z. Epub 2018 Jan 19. No abstract available.

PMID:
29350338
10.

Positive allergen reaction in allergic and nonallergic rhinitis: a systematic review.

Hamizan AW, Rimmer J, Alvarado R, Sewell WA, Kalish L, Sacks R, Harvey RJ.

Int Forum Allergy Rhinol. 2017 Sep;7(9):868-877. doi: 10.1002/alr.21988. Epub 2017 Jul 20. Review.

PMID:
28727909
11.

Polychromatic flow cytometry is more sensitive than microscopy in detecting small monoclonal plasma cell populations.

Tran DN, Smith SA, Brown DA, Parker AJ, Joseph JE, Armstrong N, Sewell WA.

Cytometry B Clin Cytom. 2017 Mar;92(2):136-144. doi: 10.1002/cyto.b.21401. Epub 2016 Aug 5.

12.

Good's syndrome: Is thymectomy the solution? Case report and literature review.

Habib AM, Thornton H, Sewell WC, Loubani M.

Asian Cardiovasc Thorac Ann. 2016 Sep;24(7):712-4. doi: 10.1177/0218492316655641. Epub 2016 Jun 28. Review.

PMID:
27357113
13.

Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay.

Sasson SC, McGill K, Wienholt L, Carr A, Brown DA, Kelleher AD, Breit SN, Sewell WA.

Pathology. 2015 Oct;47(6):564-9. doi: 10.1097/PAT.0000000000000316.

PMID:
26352111
14.

Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.

Oftedal BE, Hellesen A, Erichsen MM, Bratland E, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WA, Sozaeva LS, Zayats T, Haugarvoll K, Orlova EM, Haavik J, Johansson S, Knappskog PM, Løvås K, Wolff AS, Abramson J, Husebye ES.

Immunity. 2015 Jun 16;42(6):1185-96. doi: 10.1016/j.immuni.2015.04.021.

15.

Monoclonal precursor T-cell infiltrate in recurrent thymoma: a case report.

Sasson SC, Smith SA, Qiu MR, Stone EC, Sewell WA.

Pathology. 2015 Jun;47(4):375-7. doi: 10.1097/PAT.0000000000000257. No abstract available.

PMID:
25938353
16.

Is dosing of therapeutic immunoglobulins optimal? A review of a three-decade long debate in europe.

Kerr J, Quinti I, Eibl M, Chapel H, Späth PJ, Sewell WA, Salama A, van Schaik IN, Kuijpers TW, Peter HH.

Front Immunol. 2014 Dec 12;5:629. doi: 10.3389/fimmu.2014.00629. eCollection 2014. Review.

17.

Using calculated globulin fraction to reduce diagnostic delay in primary and secondary hypogammaglobulinaemias: results of a demonstration project.

Holding S, Khan S, Sewell WA, Jolles S, Dore PC.

Ann Clin Biochem. 2015 May;52(Pt 3):319-26. doi: 10.1177/0004563214545791. Epub 2014 Jul 14.

PMID:
25024432
18.

European consensus proposal for immunoglobulin therapies.

Sewell WA, Kerr J, Behr-Gross ME, Peter HH; Kreuth Ig Working Group.

Eur J Immunol. 2014 Aug;44(8):2207-14. doi: 10.1002/eji.201444700.

19.

IgE-associated IGHV genes from venom and peanut allergic individuals lack mutational evidence of antigen selection.

Wang Y, Jackson KJ, Davies J, Chen Z, Gaeta BA, Rimmer J, Sewell WA, Collins AM.

PLoS One. 2014 Feb 25;9(2):e89730. doi: 10.1371/journal.pone.0089730. eCollection 2014.

20.

Transitional B cell subsets in human bone marrow.

Agrawal S, Smith SA, Tangye SG, Sewell WA.

Clin Exp Immunol. 2013 Oct;174(1):53-9. doi: 10.1111/cei.12149.

21.

Phenotypic characterization of metastatic anaplastic thyroid cancer stem cells.

Li W, Reeb AN, Sewell WA, Elhomsy G, Lin RY.

PLoS One. 2013 May 28;8(5):e65095. doi: 10.1371/journal.pone.0065095. Print 2013.

22.

Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective.

Shankar-Hari M, Spencer J, Sewell WA, Rowan KM, Singer M.

Crit Care. 2012 Dec 12;16(2):206. doi: 10.1186/cc10597. Review.

23.

Polychromatic flow cytometry in the clinical laboratory.

Sewell WA, Smith SA.

Pathology. 2011 Oct;43(6):580-91. doi: 10.1097/PAT.0b013e32834a69ae. Review.

PMID:
21881537
24.

Protection against Nippostrongylus brasiliensis infection in mice is independent of GM-CSF.

Shim DS, Schilter HC, Knott ML, Almeida RA, Short RP, Mackay CR, Dent LA, Sewell WA.

Immunol Cell Biol. 2012 May;90(5):553-8. doi: 10.1038/icb.2011.69. Epub 2011 Aug 16.

PMID:
21844882
25.

Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells.

Jackson KJ, Wang Y, Gaeta BA, Pomat W, Siba P, Rimmer J, Sewell WA, Collins AM.

Immunogenetics. 2012 Jan;64(1):3-14. doi: 10.1007/s00251-011-0559-z. Epub 2011 Jul 26.

PMID:
21789596
26.

Immunotherapy of allergic diseases by bacterial products.

Sewell WA, Thomas WR.

Immunol Cell Biol. 2011 Oct;89(7):749-50. doi: 10.1038/icb.2011.24. Epub 2011 Mar 29. No abstract available.

PMID:
21445086
27.

IgE sequences in individuals living in an area of endemic parasitism show little mutational evidence of antigen selection.

Wang Y, Jackson KJ, Chen Z, Gaëta BA, Siba PM, Pomat W, Walpole E, Rimmer J, Sewell WA, Collins AM.

Scand J Immunol. 2011 May;73(5):496-504. doi: 10.1111/j.1365-3083.2011.02525.x.

28.

Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants.

Wang Y, Jackson KJ, Gäeta B, Pomat W, Siba P, Sewell WA, Collins AM.

Immunogenetics. 2011 May;63(5):259-65. doi: 10.1007/s00251-010-0510-8. Epub 2011 Jan 20.

PMID:
21249354
29.

Antigen selection in IgE antibodies from individuals with chronic rhinosinusitis with nasal polyps.

Pratt E, Collins AM, Sewell WA, Harvey RJ.

Am J Rhinol Allergy. 2010 Nov-Dec;24(6):416-21. doi: 10.2500/ajra.2010.24.3538.

PMID:
21144221
30.

Administering intravenous immunoglobulin during infection is associated with infusion reactions in selected patients.

Khan S, Abuzakouk M, Doré PC, Sewell WA.

Ir J Med Sci. 2011 Mar;180(1):125-8. doi: 10.1007/s11845-010-0654-4. Epub 2010 Dec 7.

PMID:
21136195
31.

Do ribosomopathies explain some cases of common variable immunodeficiency?

Khan S, Pereira J, Darbyshire PJ, Holding S, Doré PC, Sewell WA, Huissoon A.

Clin Exp Immunol. 2011 Jan;163(1):96-103. doi: 10.1111/j.1365-2249.2010.04280.x. Epub 2010 Nov 9. Review.

32.

Progress towards anticytokine therapy in asthma.

Sewell WA.

Immunotherapy. 2010 Sep;2(5):651-4. doi: 10.2217/imt.10.45.

PMID:
20874648
33.

Cardiac defects contribute to the pathology of spinal muscular atrophy models.

Shababi M, Habibi J, Yang HT, Vale SM, Sewell WA, Lorson CL.

Hum Mol Genet. 2010 Oct 15;19(20):4059-71. doi: 10.1093/hmg/ddq329. Epub 2010 Aug 9.

PMID:
20696672
34.

Anti-acetylcholine receptor antibody reactivity of IgG in commercial immunoglobulin preparations.

Khan S, Davies L, Cowley D, Wild G, Sewell WA.

Clin Neurol Neurosurg. 2010 Nov;112(9):835-6. doi: 10.1016/j.clineuro.2010.06.014. No abstract available.

PMID:
20619959
35.

Lichen planus in a case of Good's syndrome (thymoma and immunodeficiency).

Khan S, Campbell A, Hunt C, Sewell WA.

Interact Cardiovasc Thorac Surg. 2009 Aug;9(2):345-6. doi: 10.1510/icvts.2009.207308. Epub 2009 May 20.

PMID:
19457897
36.

Limited value of testing for intrinsic factor antibodies with negative gastric parietal cell antibodies in pernicious anaemia.

Khan S, Del-Duca C, Fenton E, Holding S, Hirst J, Doré PC, Sewell WA.

J Clin Pathol. 2009 May;62(5):439-41. doi: 10.1136/jcp.2008.060509.

PMID:
19398595
37.

Intravenous immunoglobulin-induced neutropenia.

Khan S, Doré PC, Sewell WA.

Pediatr Allergy Immunol. 2010 Aug;21(5):892-3. doi: 10.1111/j.1399-3038.2009.00885.x. Epub 2009 Apr 3. No abstract available.

PMID:
19368688
38.

The value of total IgE levels in the context of specific allergy.

Khan S, Doré PC, Sewell WA.

Pediatr Allergy Immunol. 2008 Dec;19(8):777-8. doi: 10.1111/j.1399-3038.2008.00795.x. No abstract available.

PMID:
19076566
39.

Both autoantibodies and pathogen-specific antibodies are present in immunoglobulin preparations and reflect characteristics of the donor population.

Khan S, Sims S, Raine D, Sewell WA.

J Am Acad Dermatol. 2008 Dec;59(6):1089-90. doi: 10.1016/j.jaad.2008.07.048. No abstract available.

PMID:
19022109
40.

Prescribing intravenous immunoglobulin: summary of Department of Health guidelines.

Provan D, Chapel HM, Sewell WA, O'Shaughnessy D; UK Immunoglobulin Expert Working Group.

BMJ. 2008 Oct 20;337:a1831. doi: 10.1136/bmj.a1831. No abstract available.

PMID:
18936060
41.

Antibody deficiency.

Herriot R, Sewell WA.

J Clin Pathol. 2008 Sep;61(9):994-1000. doi: 10.1136/jcp.2007.051177. Review.

PMID:
18755724
42.

The reported germline repertoire of human immunoglobulin kappa chain genes is relatively complete and accurate.

Collins AM, Wang Y, Singh V, Yu P, Jackson KJ, Sewell WA.

Immunogenetics. 2008 Nov;60(11):669-76. doi: 10.1007/s00251-008-0325-z. Epub 2008 Aug 20.

PMID:
18712520
43.

Alpha1-antitrypsin deficiency and Pi typing.

Barlow I, Sewell WA.

J Allergy Clin Immunol. 2008 Sep;122(3):658. doi: 10.1016/j.jaci.2008.06.019. Epub 2008 Jul 30. No abstract available.

PMID:
18672280
44.

Differential rates of apoptosis and recruitment limit eosinophil accumulation in the lungs of asthma-resistant CBA/Ca mice.

Tumes DJ, Wong AC, Sewell WA, McColl SR, Connolly A, Dent LA.

Mol Immunol. 2008 Aug;45(13):3609-17. doi: 10.1016/j.molimm.2008.05.002. Epub 2008 Jun 25.

PMID:
18582944
45.

Clinical immunology review series: an approach to the use of the immunology laboratory in the diagnosis of clinical allergy.

Williams P, Sewell WA, Bunn C, Pumphrey R, Read G, Jolles S.

Clin Exp Immunol. 2008 Jul;153(1):10-8. doi: 10.1111/j.1365-2249.2008.03695.x. Review.

46.

Mechanisms in allergic airway inflammation - lessons from studies in the mouse.

Shum BO, Rolph MS, Sewell WA.

Expert Rev Mol Med. 2008 May 27;10:e15. doi: 10.1017/S1462399408000707. Review.

PMID:
18503727
47.

The clinical significance of antinucleolar antibodies.

Khan S, Alvi A, Holding S, Kemp ML, Raine D, Doré PC, Sewell WA.

J Clin Pathol. 2008 Mar;61(3):283-6. doi: 10.1136/jcp.2007.049692. Erratum in: J Clin Pathol. 2008 May;61(5):688.

PMID:
18305179
48.

Both patient characteristics and IVIG product-specific mechanisms may affect eosinophils in immunoglobulin-treated Kawasaki disease.

Khan S, Doré PC, Sewell WA.

Pediatr Allergy Immunol. 2008 Mar;19(2):186-7. doi: 10.1111/j.1399-3038.2007.00658.x. No abstract available.

PMID:
18257907
49.
50.

Some cases of common variable immunodeficiency may be due to a mutation in the SBDS gene of Shwachman-Diamond syndrome.

Khan S, Hinks J, Shorto J, Schwarz MJ, Sewell WA.

Clin Exp Immunol. 2008 Mar;151(3):448-54. doi: 10.1111/j.1365-2249.2007.03556.x. Epub 2008 Jan 10. Review.

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