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Items: 1 to 50 of 203

1.

Functional consequences of co-expressing connexin40 or connexin45 with connexin43 on intercellular electrical coupling.

Thomas NM, Gray R, Fry CH, Desplantez T, Peters NS, Severs NJ, Macleod KT, Dupont E.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):191-196. doi: 10.1016/j.bbrc.2016.12.169. Epub 2016 Dec 26.

2.

Relating specific connexin co-expression ratio to connexon composition and gap junction function.

Desplantez T, Grikscheit K, Thomas NM, Peters NS, Severs NJ, Dupont E.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):195-202. doi: 10.1016/j.yjmcc.2015.11.008. Epub 2015 Nov 6.

3.

Characterisation of connexin expression and electrophysiological properties in stable clones of the HL-1 myocyte cell line.

Dias P, Desplantez T, El-Harasis MA, Chowdhury RA, Ullrich ND, Cabestrero de Diego A, Peters NS, Severs NJ, MacLeod KT, Dupont E.

PLoS One. 2014 Feb 28;9(2):e90266. doi: 10.1371/journal.pone.0090266. eCollection 2014.

4.

Localisation of SCN10A gene product Na(v)1.8 and novel pain-related ion channels in human heart.

Facer P, Punjabi PP, Abrari A, Kaba RA, Severs NJ, Chambers J, Kooner JS, Anand P.

Int Heart J. 2011;52(3):146-52.

5.

SR-PSOX at sites predisposed to atherosclerotic lesion formation mediates monocyte-endothelial cell adhesion.

Hofnagel O, Engel T, Severs NJ, Robenek H, Buers I.

Atherosclerosis. 2011 Aug;217(2):371-8. doi: 10.1016/j.atherosclerosis.2011.04.021. Epub 2011 May 5.

PMID:
21612780
6.

Topography of lipid droplet-associated proteins: insights from freeze-fracture replica immunogold labeling.

Robenek H, Buers I, Robenek MJ, Hofnagel O, Ruebel A, Troyer D, Severs NJ.

J Lipids. 2011;2011:409371. doi: 10.1155/2011/409371. Epub 2010 Dec 26.

7.

Lipid droplet associated proteins: an emerging role in atherogenesis.

Buers I, Hofnagel O, Ruebel A, Severs NJ, Robenek H.

Histol Histopathol. 2011 May;26(5):631-42. doi: 10.14670/HH-26.631. Review.

PMID:
21432779
8.

Influence of v5/6-His tag on the properties of gap junction channels composed of connexin43, connexin40 or connexin45.

Desplantez T, Halliday D, Dupont E, Severs NJ, Weingart R.

J Membr Biol. 2011 Apr;240(3):139-50. doi: 10.1007/s00232-011-9352-z. Epub 2011 Mar 19.

9.

Controlled and stochastic retention concentrates dynein at microtubule ends to keep endosomes on track.

Schuster M, Kilaru S, Ashwin P, Lin C, Severs NJ, Steinberg G.

EMBO J. 2011 Feb 16;30(4):652-64. doi: 10.1038/emboj.2010.360. Epub 2011 Jan 28.

10.

Genetic variation in SCN10A influences cardiac conduction.

Chambers JC, Zhao J, Terracciano CM, Bezzina CR, Zhang W, Kaba R, Navaratnarajah M, Lotlikar A, Sehmi JS, Kooner MK, Deng G, Siedlecka U, Parasramka S, El-Hamamsy I, Wass MN, Dekker LR, de Jong JS, Sternberg MJ, McKenna W, Severs NJ, de Silva R, Wilde AA, Anand P, Yacoub M, Scott J, Elliott P, Wood JN, Kooner JS.

Nat Genet. 2010 Feb;42(2):149-52. doi: 10.1038/ng.516. Epub 2010 Jan 10.

PMID:
20062061
11.

Lipid droplet growth by fusion: insights from freeze-fracture imaging.

Robenek H, Severs NJ.

J Cell Mol Med. 2009 Nov-Dec;13(11-12):4657-61. doi: 10.1111/j.1582-4934.2009.00950.x. Epub 2009 Oct 23.

12.

Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes.

Gadelha C, Rothery S, Morphew M, McIntosh JR, Severs NJ, Gull K.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17425-30. doi: 10.1073/pnas.0909289106. Epub 2009 Oct 1.

13.

TIP47, a lipid cargo protein involved in macrophage triglyceride metabolism.

Buers I, Robenek H, Lorkowski S, Nitschke Y, Severs NJ, Hofnagel O.

Arterioscler Thromb Vasc Biol. 2009 May;29(5):767-73. doi: 10.1161/ATVBAHA.108.182675. Epub 2009 Mar 12.

14.

Human connexin31.9, unlike its orthologous protein connexin30.2 in the mouse, is not detectable in the human cardiac conduction system.

Kreuzberg MM, Liebermann M, Segschneider S, Dobrowolski R, Dobrzynski H, Kaba R, Rowlinson G, Dupont E, Severs NJ, Willecke K.

J Mol Cell Cardiol. 2009 Apr;46(4):553-9. doi: 10.1016/j.yjmcc.2008.12.007. Epub 2008 Dec 29.

PMID:
19168070
15.

Compartmentalization of proteins in lipid droplet biogenesis.

Robenek H, Buers I, Hofnagel O, Robenek MJ, Troyer D, Severs NJ.

Biochim Biophys Acta. 2009 Jun;1791(6):408-18. doi: 10.1016/j.bbalip.2008.12.001. Epub 2008 Dec 11. Review.

PMID:
19118639
16.

Freeze-fracture replica immunolabelling reveals caveolin-1 in the human cardiomyocyte plasma membrane.

Robenek H, Weissen-Plenz G, Severs NJ.

J Cell Mol Med. 2008 Dec;12(6A):2519-21. doi: 10.1111/j.1582-4934.2008.00498.x. Epub 2008 Sep 13.

17.

Coexpression of connexin 45 with connexin 43 decreases gap junction size.

Grikscheit K, Thomas N, Bruce AF, Rothery S, Chan J, Severs NJ, Dupont E.

Cell Commun Adhes. 2008 May;15(1):185-93. doi: 10.1080/15419060802013943.

PMID:
18649189
18.

GFP-tagged proteins visualized by freeze-fracture immuno-electron microscopy: a new tool in cellular and molecular medicine.

Robenek H, Buers I, Hofnagel O, Lorkowski S, Severs NJ.

J Cell Mol Med. 2009 Jul;13(7):1381-90. doi: 10.1111/j.1582-4934.2008.00407.x. Epub 2008 Jul 9.

19.

Freeze-fracture cytochemistry in cell biology.

Severs NJ, Robenek H.

Methods Cell Biol. 2008;88:181-204. doi: 10.1016/S0091-679X(08)00411-1. Review.

PMID:
18617035
20.

Remodelling of gap junctions and connexin expression in diseased myocardium.

Severs NJ, Bruce AF, Dupont E, Rothery S.

Cardiovasc Res. 2008 Oct 1;80(1):9-19. doi: 10.1093/cvr/cvn133. Epub 2008 Jun 2. Review.

21.

Recent advances in freeze-fracture electron microscopy: the replica immunolabeling technique.

Robenek H, Severs NJ.

Biol Proced Online. 2008 Jan 28;10:9-19. doi: 10.1251/bpo138.

23.

Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.

Bruce AF, Rothery S, Dupont E, Severs NJ.

Cardiovasc Res. 2008 Mar 1;77(4):757-65. Epub 2007 Dec 4.

24.

Function of scavenger receptor class A type I/II is not important for smooth muscle foam cell formation.

Luechtenborg B, Hofnagel O, Weissen-Plenz G, Severs NJ, Robenek H.

Eur J Cell Biol. 2008 Feb;87(2):91-9. Epub 2007 Nov 5.

PMID:
17980455
25.

Gap junction channels and cardiac impulse propagation.

Desplantez T, Dupont E, Severs NJ, Weingart R.

J Membr Biol. 2007 Aug;218(1-3):13-28. Epub 2007 Jul 28. Review.

PMID:
17661127
26.

Relationship of connexin43 expression to phenotypic modulation in cultured human aortic smooth muscle cells.

Matsushita T, Rama A, Charolidi N, Dupont E, Severs NJ.

Eur J Cell Biol. 2007 Oct;86(10):617-28. Epub 2007 Jul 24.

PMID:
17651863
27.

Freeze-fracture electron microscopy.

Severs NJ.

Nat Protoc. 2007;2(3):547-76.

PMID:
17406618
28.

Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis.

Robenek H, Hofnagel O, Buers I, Robenek MJ, Troyer D, Severs NJ.

J Cell Sci. 2006 Oct 15;119(Pt 20):4215-24. Epub 2006 Sep 19.

29.

Butyrophilin controls milk fat globule secretion.

Robenek H, Hofnagel O, Buers I, Lorkowski S, Schnoor M, Robenek MJ, Heid H, Troyer D, Severs NJ.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10385-10390. doi: 10.1073/pnas.0600795103. Epub 2006 Jun 26.

30.

Alterations in cardiac connexin expression in cardiomyopathies.

Severs NJ, Dupont E, Thomas N, Kaba R, Rothery S, Jain R, Sharpey K, Fry CH.

Adv Cardiol. 2006;42:228-42. Review.

PMID:
16646594
31.

Human atrial conduction and arrhythmogenesis correlates with conformational exposure of specific epitopes on the connexin40 carboxyl tail.

Kanagaratnam P, Dupont E, Rothery S, Coppen S, Severs NJ, Peters NS.

J Mol Cell Cardiol. 2006 May;40(5):675-87.

PMID:
16600287
32.

Remodeling of myocardial sleeve and gap junctions in canine superior vena cava after rapid pacing.

Yeh HI, Lai YJ, Lee SH, Chen ST, Ko YS, Chen SA, Severs NJ, Tsai CH.

Basic Res Cardiol. 2006 Jul;101(4):269-80. Epub 2006 Mar 27.

PMID:
16568251
33.

Loss of desmoplakin isoform I causes early onset cardiomyopathy and heart failure in a Naxos-like syndrome.

Uzumcu A, Norgett EE, Dindar A, Uyguner O, Nisli K, Kayserili H, Sahin SE, Dupont E, Severs NJ, Leigh IM, Yuksel-Apak M, Kelsell DP, Wollnik B.

J Med Genet. 2006 Feb;43(2):e5.

34.

Up-regulation of connexin43 correlates with increased synthetic activity and enhanced contractile differentiation in TGF-beta-treated human aortic smooth muscle cells.

Rama A, Matsushita T, Charolidi N, Rothery S, Dupont E, Severs NJ.

Eur J Cell Biol. 2006 May;85(5):375-86. Epub 2006 Jan 25.

PMID:
16442184
35.

Pravastatin inhibits expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in Watanabe heritable hyperlipidemic rabbits: a new pleiotropic effect of statins.

Hofnagel O, Luechtenborg B, Eschert H, Weissen-Plenz G, Severs NJ, Robenek H.

Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):604-10. Epub 2005 Dec 22.

36.

Sex differences in connexin-43 expression in left ventricles of aging rats.

Tribulov√° N, Dupont E, Soukup T, Okruhlicov√° L, Severs NJ.

Physiol Res. 2005;54(6):705-8.

37.

High-resolution en-face visualization of the cardiomyocyte plasma membrane reveals distinctive distributions of spectrin and dystrophin.

Stevenson SA, Cullen MJ, Rothery S, Coppen SR, Severs NJ.

Eur J Cell Biol. 2005 Dec;84(12):961-71. Epub 2005 Oct 19.

PMID:
16325505
38.

Dystrophin and the cardiomyocyte membrane cytoskeleton in the healthy and failing heart.

Kaprielian RR, Severs NJ.

Heart Fail Rev. 2000 Oct;5(3):221-38.

PMID:
16228906
39.

Lipid droplets gain PAT family proteins by interaction with specialized plasma membrane domains.

Robenek H, Robenek MJ, Buers I, Lorkowski S, Hofnagel O, Troyer D, Severs NJ.

J Biol Chem. 2005 Jul 15;280(28):26330-8. Epub 2005 May 16.

40.

Upregulation of connexin43 gap junctions between neointimal smooth muscle cells.

Plenz G, Ko YS, Yeh HI, Eschert H, Sindermann JR, Dorszewski A, Hofnagel O, Robenek H, Breithardt G, Severs NJ.

Eur J Cell Biol. 2004 Oct;83(10):521-30.

PMID:
15679098
41.

Gap junction alterations in human cardiac disease.

Severs NJ, Coppen SR, Dupont E, Yeh HI, Ko YS, Matsushita T.

Cardiovasc Res. 2004 May 1;62(2):368-77. Review.

PMID:
15094356
42.

Remodelling of gap junctions and connexin expression in heart disease.

Severs NJ, Dupont E, Coppen SR, Halliday D, Inett E, Baylis D, Rothery S.

Biochim Biophys Acta. 2004 Mar 23;1662(1-2):138-48. Review.

43.

Relationship between connexins and atrial activation during human atrial fibrillation.

Kanagaratnam P, Cherian A, Stanbridge RD, Glenville B, Severs NJ, Peters NS.

J Cardiovasc Electrophysiol. 2004 Feb;15(2):206-16.

PMID:
15028052
44.

Spontaneous activity and electrical coupling in human detrusor smooth muscle: implications for detrusor overactivity?

Fry CH, Sui GP, Severs NJ, Wu C.

Urology. 2004 Mar;63(3 Suppl 1):3-10. Review.

PMID:
15013646
45.

Lipids partition caveolin-1 from ER membranes into lipid droplets: updating the model of lipid droplet biogenesis.

Robenek MJ, Severs NJ, Schlattmann K, Plenz G, Zimmer KP, Troyer D, Robenek H.

FASEB J. 2004 May;18(7):866-8. Epub 2004 Mar 4.

PMID:
15001554
46.

Three-dimensional reconstruction of the rabbit atrioventricular conduction axis by combining histological, desmin, and connexin mapping data.

Ko YS, Yeh HI, Ko YL, Hsu YC, Chen CF, Wu S, Lee YS, Severs NJ.

Circulation. 2004 Mar 9;109(9):1172-9. Epub 2004 Feb 9.

48.

Impedance measurements and connexin expression in human detrusor muscle from stable and unstable bladders.

Sui GP, Coppen SR, Dupont E, Rothery S, Gillespie J, Newgreen D, Severs NJ, Fry CH.

BJU Int. 2003 Aug;92(3):297-305.

49.

Reduced expression of endothelial connexin37 and connexin40 in hyperlipidemic mice: recovery of connexin37 after 7-day simvastatin treatment.

Yeh HI, Lu CS, Wu YJ, Chen CC, Hong RC, Ko YS, Shiao MS, Severs NJ, Tsai CH.

Arterioscler Thromb Vasc Biol. 2003 Aug 1;23(8):1391-7. Epub 2003 Jun 26.

50.

Age-related changes in the protective effect of chronic administration of L-arginine on post-ischemic recovery of endothelial function.

Nakamura K, Al-Ruzzeh S, Chester AH, Dewar A, Rothery S, Severs NJ, Yacoub MH, Amrani M.

Eur J Cardiothorac Surg. 2003 Apr;23(4):626-32.

PMID:
12694788

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