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Items: 8


Efficacy of caspofungin as salvage therapy for invasive aspergillosis compared to standard therapy in a historical cohort.

Hiemenz JW, Raad II, Maertens JA, Hachem RY, Saah AJ, Sable CA, Chodakewitz JA, Severino ME, Saddier P, Berman RS, Ryan DM, Dinubile MJ, Patterson TF, Denning DW, Walsh TJ.

Eur J Clin Microbiol Infect Dis. 2010 Nov;29(11):1387-94. doi: 10.1007/s10096-010-1013-0. Epub 2010 Aug 12.


A strategic view on the use of pharmacodynamic biomarkers in early clinical drug development.

Severino ME, Dubose RF, Patterson SD.

IDrugs. 2006 Dec;9(12):849-53.


Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.

Simon JS, Karnoub MC, Devlin DJ, Arreaza MG, Qiu P, Monks SA, Severino ME, Deutsch P, Palmisano J, Sachs AB, Bayne ML, Plump AS, Schadt EE.

Genomics. 2005 Dec;86(6):648-56. Epub 2005 Nov 16.


Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling.

Hardwick JS, Yang Y, Zhang C, Shi B, McFall R, Koury EJ, Hill SL, Dai H, Wasserman R, Phillips RL, Weinstein EJ, Kohl NE, Severino ME, Lamb JR, Sepp-Lorenzino L.

Mol Cancer Ther. 2005 Mar;4(3):413-25.


CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of V alpha 24J alpha Q T cells: a feedback mechanism for immune regulation.

Yang OO, Racke FK, Nguyen PT, Gausling R, Severino ME, Horton HF, Byrne MC, Strominger JL, Wilson SB.

J Immunol. 2000 Oct 1;165(7):3756-62.


Inhibition of human immunodeficiency virus type 1 replication in primary CD4(+) T lymphocytes, monocytes, and dendritic cells by cytotoxic T lymphocytes.

Severino ME, Sipsas NV, Nguyen PT, Kalams SA, Walker BD, Johnson RP, Yang OO.

J Virol. 2000 Jul;74(14):6695-9.


Cyclosporine preferentially inhibits clonal deletion of CD8-positive T cells with an MHC class II restricted autoreactive T-cell receptor.

Severino ME, Laulis MK, Horwitz LR, Hess AD.

Transplant Proc. 1993 Feb;25(1 Pt 1):520-3. No abstract available.


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