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Items: 27

1.

135La as an Auger-electron emitter for targeted internal radiotherapy.

Fonslet J, Lee BQ, Tran TA, Siragusa M, Jensen M, Kibédi T, Stuchbery AE, Severin GW.

Phys Med Biol. 2017 Dec 29;63(1):015026. doi: 10.1088/1361-6560/aa9b44.

PMID:
29286003
2.

<sup>135</sup>La as an auger-electron emitter for targeted internal radiotherapy.

Fonslet J, Lee BQ, Tran TA, Siragusa M, Jensen M, Kibedi T, Stuchbery AE, Severin GW.

Phys Med Biol. 2017 Nov 17. doi: 10.1088/1361-6560/aa9b44. [Epub ahead of print]

PMID:
29148428
3.

Remote-loading of liposomes with manganese-52 and in vivo evaluation of the stabilities of 52Mn-DOTA and 64Cu-DOTA using radiolabelled liposomes and PET imaging.

Jensen AI, Severin GW, Hansen AE, Fliedner FP, Eliasen R, Parhamifar L, Kjær A, Andresen TL, Henriksen JR.

J Control Release. 2018 Jan 10;269:100-109. doi: 10.1016/j.jconrel.2017.11.006. Epub 2017 Nov 6.

PMID:
29122662
4.

Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector.

Severin GW, Kristensen LK, Nielsen CH, Fonslet J, Jensen AI, Frellsen AF, Jensen KM, Elema DR, Maecke H, Kjær A, Johnston K, Köster U.

Front Med (Lausanne). 2017 Jul 12;4:98. doi: 10.3389/fmed.2017.00098. eCollection 2017.

5.

Imaging neuronal pathways with 52Mn PET: Toxicity evaluation in rats.

Napieczynska H, Severin GW, Fonslet J, Wiehr S, Menegakis A, Pichler BJ, Calaminus C.

Neuroimage. 2017 Sep;158:112-125. doi: 10.1016/j.neuroimage.2017.06.058. Epub 2017 Jun 30.

PMID:
28669916
6.

Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes.

Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W.

Diabetes. 2017 Aug;66(8):2163-2174. doi: 10.2337/db16-1285. Epub 2017 May 17.

7.

Optimized procedures for manganese-52: Production, separation and radiolabeling.

Fonslet J, Tietze S, Jensen AI, Graves SA, Severin GW.

Appl Radiat Isot. 2017 Mar;121:38-43. doi: 10.1016/j.apradiso.2016.11.021. Epub 2016 Dec 21.

PMID:
28024217
8.

Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines.

Edmonds S, Volpe A, Shmeeda H, Parente-Pereira AC, Radia R, Baguña-Torres J, Szanda I, Severin GW, Livieratos L, Blower PJ, Maher J, Fruhwirth GO, Gabizon A, T M de Rosales R.

ACS Nano. 2016 Nov 22;10(11):10294-10307. Epub 2016 Oct 26.

9.

Mouse Positron Emission Tomography Study of the Biodistribution of Gold Nanoparticles with Different Surface Coatings Using Embedded Copper-64.

Frellsen AF, Hansen AE, Jølck RI, Kempen PJ, Severin GW, Rasmussen PH, Kjær A, Jensen AT, Andresen TL.

ACS Nano. 2016 Nov 22;10(11):9887-9898. Epub 2016 Oct 25.

PMID:
27754658
10.

Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging.

Yang D, Severin GW, Dougherty CA, Lombardi R, Chen D, Van Dort ME, Barnhart TE, Ross BD, Mazar AP, Hong H.

Oncotarget. 2016 Nov 8;7(45):73912-73924. doi: 10.18632/oncotarget.12528.

11.

Stable and high-yielding intrinsic (59) Fe-radiolabeling of the intravenous iron preparations Monofer and Cosmofer.

Jensen AI, Severin GW, Andreasen HB, Rasmussen PH.

J Labelled Comp Radiopharm. 2016 Jul;59(9):375-82. doi: 10.1002/jlcr.3416. Epub 2016 Jun 16.

PMID:
27311359
12.

ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo.

Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33. doi: 10.1073/pnas.1518836113. Epub 2016 Jan 19.

13.

Novel Preparation Methods of (52)Mn for ImmunoPET Imaging.

Graves SA, Hernandez R, Fonslet J, England CG, Valdovinos HF, Ellison PA, Barnhart TE, Elema DR, Theuer CP, Cai W, Nickles RJ, Severin GW.

Bioconjug Chem. 2015 Oct 21;26(10):2118-24. doi: 10.1021/acs.bioconjchem.5b00414. Epub 2015 Sep 10.

14.

Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [(45)Ti](salan)Ti(dipic).

Severin GW, Nielsen CH, Jensen AI, Fonslet J, Kjær A, Zhuravlev F.

J Med Chem. 2015 Sep 24;58(18):7591-5. doi: 10.1021/acs.jmedchem.5b01167. Epub 2015 Sep 3.

PMID:
26312993
15.

Automated synthesis and PET evaluation of both enantiomers of [¹⁸F]FMISO.

Revunov E, Jørgensen JT, Jensen AI, Hansen AE, Severin GW, Kjær A, Zhuravlev F.

Nucl Med Biol. 2015 Apr;42(4):413-9. doi: 10.1016/j.nucmedbio.2014.12.010. Epub 2014 Dec 24.

PMID:
25595134
16.

The impact of weakly bound ⁸⁹Zr on preclinical studies: non-specific accumulation in solid tumors and aspergillus infection.

Severin GW, Jørgensen JT, Wiehr S, Rolle AM, Hansen AE, Maurer A, Hasenberg M, Pichler B, Kjær A, Jensen AI.

Nucl Med Biol. 2015 Apr;42(4):360-8. doi: 10.1016/j.nucmedbio.2014.11.005. Epub 2014 Nov 22.

PMID:
25583221
17.

ImmunoPET and near-infrared fluorescence imaging of CD105 expression using a monoclonal antibody dual-labeled with (89)Zr and IRDye 800CW.

Zhang Y, Hong H, Severin GW, Engle JW, Yang Y, Goel S, Nathanson AJ, Liu G, Nickles RJ, Leigh BR, Barnhart TE, Cai W.

Am J Transl Res. 2012;4(3):333-46. Epub 2012 Jul 27.

18.

Multimodality imaging of breast cancer experimental lung metastasis with bioluminescence and a monoclonal antibody dual-labeled with 89Zr and IRDye 800CW.

Hong H, Zhang Y, Severin GW, Yang Y, Engle JW, Niu G, Nickles RJ, Chen X, Leigh BR, Barnhart TE, Cai W.

Mol Pharm. 2012 Aug 6;9(8):2339-49. doi: 10.1021/mp300277f. Epub 2012 Jul 19.

19.

Cyclotron produced ⁴⁴gSc from natural calcium.

Severin GW, Engle JW, Valdovinos HF, Barnhart TE, Nickles RJ.

Appl Radiat Isot. 2012 Aug;70(8):1526-30. doi: 10.1016/j.apradiso.2012.04.030. Epub 2012 May 24.

20.

Very high specific activity ⁶⁶/⁶⁸Ga from zinc targets for PET.

Engle JW, Lopez-Rodriguez V, Gaspar-Carcamo RE, Valdovinos HF, Valle-Gonzalez M, Trejo-Ballado F, Severin GW, Barnhart TE, Nickles RJ, Avila-Rodriguez MA.

Appl Radiat Isot. 2012 Aug;70(8):1792-6. doi: 10.1016/j.apradiso.2012.03.030. Epub 2012 Mar 28.

21.

The unrealized potential of (34m)Cl for radiopharmaceutical research with PET.

Engle JW, Barnhart TE, Severin GW, Nickles RJ.

Curr Radiopharm. 2011 Apr;4(2):102-8. Review.

PMID:
22191649
22.

Cross sections of the 36Ar(d,α)34mCl, 40Ar(d,α)38Cl, and 40Ar(d,p)41Ar nuclear reactions below 8.4 MeV.

Engle JW, Severin GW, Barnhart TE, Knutson LD, Nickles RJ.

Appl Radiat Isot. 2012 Feb;70(2):355-9. doi: 10.1016/j.apradiso.2011.10.003. Epub 2011 Oct 18.

23.

Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105.

Hong H, Severin GW, Yang Y, Engle JW, Zhang Y, Barnhart TE, Liu G, Leigh BR, Nickles RJ, Cai W.

Eur J Nucl Med Mol Imaging. 2012 Jan;39(1):138-48. doi: 10.1007/s00259-011-1930-x. Epub 2011 Sep 10.

24.

HaloTag: a novel reporter gene for positron emission tomography.

Hong H, Benink HA, Zhang Y, Yang Y, Uyeda HT, Engle JW, Severin GW, McDougall MG, Barnhart TE, Klaubert DH, Nickles RJ, Fan F, Cai W.

Am J Transl Res. 2011 Aug 15;3(4):392-403. Epub 2011 Jul 28.

25.

A superconducting beta spectrometer.

Knutson LD, Severin GW, Cotter SL, Zhan L, Voytas PA, George EA.

Rev Sci Instrum. 2011 Jul;82(7):073302. doi: 10.1063/1.3608454.

PMID:
21806177
26.

89Zr radiochemistry for positron emission tomography.

Severin GW, Engle JW, Barnhart TE, Nickles RJ.

Med Chem. 2011 Sep;7(5):389-94. Review.

27.

Bisphosphonates are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase.

Montalvetti A, Bailey BN, Martin MB, Severin GW, Oldfield E, Docampo R.

J Biol Chem. 2001 Sep 7;276(36):33930-7. Epub 2001 Jul 2.

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