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Optimizing gentamicin conventional and extended interval dosing in neonates using Monte Carlo simulation - a retrospective study.

Bergenwall M, Walker SAN, Elligsen M, Iaboni DC, Findlater C, Seto W, Ng E.

BMC Pediatr. 2019 Sep 6;19(1):318. doi: 10.1186/s12887-019-1676-3.


Hepatitis B core-related antigen levels after HBeAg seroconversion is associated with the development of hepatocellular carcinoma.

To WP, Mak LY, Wong DK, Fung J, Liu F, Seto WK, Lai CL, Yuen MF.

J Viral Hepat. 2019 Aug 16. doi: 10.1111/jvh.13191. [Epub ahead of print]


Targeted genomic profiling identifies frequent deleterious mutations in FAT4 and TP53 genes in HBV-associated hepatocellular carcinoma.

Huang FY, Wong DK, Tsui VW, Seto WK, Mak LY, Cheung TT, Lai KK, Yuen MF.

BMC Cancer. 2019 Aug 8;19(1):789. doi: 10.1186/s12885-019-6002-9.


Choosing medications wisely: Is it time to address paediatric polypharmacy?

Bogler O, Roth D, Feinstein J, Strzelecki M, Seto W, Cohen E.

Paediatr Child Health. 2019 Aug;24(5):303-305. doi: 10.1093/pch/pxy188. Epub 2019 Jan 5.


Suboptimal treatment of dyslipidemia in patients with nonalcoholic fatty liver disease.

Khoo S, Wong VW, Goh GB, Fan J, Chan WK, Seto WK, Chow WC.

J Gastroenterol Hepatol. 2019 Jul 23. doi: 10.1111/jgh.14794. [Epub ahead of print]


Diabetes Increases Risk of Gastric Cancer After Helicobacter pylori Eradication: A Territory-Wide Study With Propensity Score Analysis.

Cheung KS, Chan EW, Chen L, Seto WK, Wong ICK, Leung WK.

Diabetes Care. 2019 Sep;42(9):1769-1775. doi: 10.2337/dc19-0437. Epub 2019 Jul 11.


Application of Big Data analysis in gastrointestinal research.

Cheung KS, Leung WK, Seto WK.

World J Gastroenterol. 2019 Jun 28;25(24):2990-3008. doi: 10.3748/wjg.v25.i24.2990. Review.


Long-term data on entecavir treatment for treatment-naive or lamivudine-resistant chronic hepatitis B infection in kidney transplant recipients.

Yap DYH, Tang C, Fung JYY, Seto WK, Ma MKM, Choy BY, Chan TM.

Transpl Infect Dis. 2019 Jul 8:e13143. doi: 10.1111/tid.13143. [Epub ahead of print]


In Vitro and In Vivo Renoprotective Effects of Telbivudine in Chronic Hepatitis B Patients Receiving Nucleotide Analogue.

Mak LY, Liu SH, Yap DY, Seto WK, Wong DK, Fung J, Chan TM, Lai CL, Yuen MF.

Dig Dis Sci. 2019 Jul 6. doi: 10.1007/s10620-019-05717-0. [Epub ahead of print]


Among Patients with Undetectable Hepatitis B Surface Antigen and Hepatocellular Carcinoma, a High Proportion Has Integration of HBV DNA into Hepatocyte DNA and No Cirrhosis.

Wong DK, Cheng SCY, Lung-Yi Mak L, Wai-Pan To E, Cheuk-Lam Lo R, Cheung TT, Seto WK, Fung J, Man K, Lai CL, Yuen MF.

Clin Gastroenterol Hepatol. 2019 Jun 25. pii: S1542-3565(19)30667-6. doi: 10.1016/j.cgh.2019.06.029. [Epub ahead of print]


Plasma Fibronectin Levels Identified via Quantitative Proteomics Profiling Predicts Hepatitis B Surface Antigen Seroclearance in Chronic Hepatitis B.

Liu F, Seto WK, Wong DK, Huang FY, Cheung KS, Mak LY, Sharma R, Zhang S, Fung J, Lai CL, Yuen MF.

J Infect Dis. 2019 Aug 9;220(6):940-950. doi: 10.1093/infdis/jiz223.


Epidemiology, characteristics, and survival of post-colonoscopy colorectal cancer in Asia: A population-based study.

Cheung KS, Chen L, Seto WK, Leung WK.

J Gastroenterol Hepatol. 2019 Apr 1. doi: 10.1111/jgh.14674. [Epub ahead of print]


New Biomarkers of Chronic Hepatitis B.

Mak LY, Seto WK, Fung J, Yuen MF.

Gut Liver. 2019 Mar 5. doi: 10.5009/gnl18425. [Epub ahead of print]


Serum Mac-2 binding protein glycosylation isomer level predicts hepatocellular carcinoma development in E-negative chronic hepatitis B patients.

Mak LY, To WP, Wong DK, Fung J, Liu F, Seto WK, Lai CL, Yuen MF.

World J Gastroenterol. 2019 Mar 21;25(11):1398-1408. doi: 10.3748/wjg.v25.i11.1398.


Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long-term nucleoside analogue.

Mak LY, Lee CH, Cheung KS, Wong DK, Liu F, Hui RW, Fung J, Xu A, Lam KS, Yuen MF, Seto WK.

Liver Int. 2019 Jul;39(7):1217-1225. doi: 10.1111/liv.14104. Epub 2019 Apr 11.


Fibrosis evolution in chronic hepatitis B e antigen-negative patients across a 10-year interval.

Mak LY, Seto WK, Hui RW, Fung J, Wong DK, Lai CL, Yuen MF.

J Viral Hepat. 2019 Jul;26(7):818-827. doi: 10.1111/jvh.13095. Epub 2019 Apr 16.


Statins reduce the progression of non-advanced adenomas to colorectal cancer: a postcolonoscopy study in 187 897 patients.

Cheung KS, Chen L, Chan EW, Seto WK, Wong ICK, Leung WK.

Gut. 2019 Feb 26. pii: gutjnl-2018-317714. doi: 10.1136/gutjnl-2018-317714. [Epub ahead of print]


Serum Mac-2-binding protein glycosylation isomer and risk of hepatocellular carcinoma in entecavir-treated chronic hepatitis B patients.

Mak LY, Ko M, To E, Wong DK, Ma JH, Hui TL, Seto WK, Fung J, Lai CL, Yuen MF.

J Gastroenterol Hepatol. 2019 Feb 20. doi: 10.1111/jgh.14637. [Epub ahead of print]


Are reusable blood collection tube holders the culprit for nosocomial hepatitis C virus transmission?

Tsang DNC, Ip M, Chan PKS, Ching PTY, Lam HS, Seto WH.

Infect Control Hosp Epidemiol. 2019 Feb;40(2):250-251. doi: 10.1017/ice.2018.302. No abstract available.


Chronic hepatitis B and metabolic risk factors: A call for rigorous longitudinal studies.

Seto WK.

World J Gastroenterol. 2019 Jan 21;25(3):282-286. doi: 10.3748/wjg.v25.i3.282.


Correlation of serum Mac-2-binding protein glycosylation isomer (M2BPGi) and liver stiffness in chronic hepatitis B infection.

Mak LY, Wong DK, Seto WK, Ning Q, Cheung KS, Fung J, Lai CL, Yuen MF.

Hepatol Int. 2019 Mar;13(2):148-156. doi: 10.1007/s12072-019-09928-5. Epub 2019 Jan 22.


A Territorywide Prevalence Study on Blood-Borne and Enteric Viral Hepatitis in Hong Kong.

Liu KSH, Seto WK, Lau EHY, Wong DK, Lam YF, Cheung KS, Mak LY, Ko KL, To WP, Law MWK, Wu JT, Lai CL, Yuen MF.

J Infect Dis. 2019 May 24;219(12):1924-1933. doi: 10.1093/infdis/jiz038.


Novel developments of hepatitis B: treatment goals, agents and monitoring tools.

Mak LY, Seto WK, Fung J, Yuen MF.

Expert Rev Clin Pharmacol. 2019 Feb;12(2):109-120. doi: 10.1080/17512433.2019.1567327. Epub 2019 Jan 21. Review.


Relationship between cyclosporine area-under-the curve and acute graft versus host disease in pediatric patients undergoing hematopoietic stem cell transplant: A prospective, multicenter study.

Schechter T, Lewis VA, Schultz KR, Mitchell D, Chen S, Seto W, Teuffel O, Gibson P, Doyle JJ, Gassas A, Sung L, Lee Dupuis L.

Pediatr Hematol Oncol. 2018 May;35(4):288-296. doi: 10.1080/08880018.2018.1520948. Epub 2018 Dec 28.


Chronic hepatitis B virus infection.

Seto WK, Lo YR, Pawlotsky JM, Yuen MF.

Lancet. 2018 Nov 24;392(10161):2313-2324. doi: 10.1016/S0140-6736(18)31865-8. Review.


Metformin Use and Gastric Cancer Risk in Diabetic Patients After Helicobacter pylori Eradication.

Cheung KS, Chan EW, Wong AYS, Chen L, Seto WK, Wong ICK, Leung WK.

J Natl Cancer Inst. 2019 May 1;111(5):484-489. doi: 10.1093/jnci/djy144.


Rates of metachronous adenoma after curative resection for left-sided or right-sided colon cancer.

Lam YF, Seto WK, Tong T, Cheung KS, Lo O, Hung IF, Law WL, Leung WK.

Intest Res. 2018 Oct;16(4):619-627. doi: 10.5217/ir.2018.00013. Epub 2018 Oct 10.


Monitoring and Treatment of Patients Undergoing Immunotherapy With Anti-CD20 Who are Exposed to HBV.

Seto WK, Chan TS, Hwang YY, Mak LY, Wong DK, Fung J, Liu KS, Cheung KS, Lai CL, Kwong YL, Yuen MF.

Clin Gastroenterol Hepatol. 2019 Jun;17(7):1410-1412. doi: 10.1016/j.cgh.2018.09.020. Epub 2018 Sep 19.


Determinants of methicillin-resistant Staphylococcus aureus (MRSA) prevalence in the Asia-Pacific region: A systematic review and meta-analysis.

Lim WW, Wu P, Bond HS, Wong JY, Ni K, Seto WH, Jit M, Cowling BJ.

J Glob Antimicrob Resist. 2019 Mar;16:17-27. doi: 10.1016/j.jgar.2018.08.014. Epub 2018 Aug 23. Review.


Prognostic Value of Hepatorenal Function By Modified Model for End-stage Liver Disease (MELD) Score in Patients Undergoing Tricuspid Annuloplasty.

Chen Y, Liu YX, Seto WK, Wu MZ, Yu YJ, Lam YM, Au WK, Chan D, Sit KY, Ho LM, Tse HF, Yiu KH.

J Am Heart Assoc. 2018 Jul 13;7(14). pii: e009020. doi: 10.1161/JAHA.118.009020.


Risk of viral reactivation in patients with occult hepatitis B virus infection during ruxolitinib treatment.

Gill H, Leung GMK, Seto WK, Kwong YL.

Ann Hematol. 2019 Jan;98(1):215-218. doi: 10.1007/s00277-018-3405-7. Epub 2018 Jun 26. No abstract available.


Fatal pancytopenia due to albendazole treatment for strongyloidiasis.

Xing F, Ye H, Yang J, Chan JF, Seto WK, Pai PM, Yuen KY, Hung DL.

IDCases. 2018 Apr 4;12:112-116. doi: 10.1016/j.idcr.2018.04.002. eCollection 2018.


Improved Bone Safety of Tenofovir Alafenamide Compared to Tenofovir Disoproxil Fumarate Over 2 Years in Patients With Chronic HBV Infection.

Seto WK, Asahina Y, Brown TT, Peng CY, Stanciu C, Abdurakhmanov D, Tabak F, Nguyen TT, Chuang WL, Inokuma T, Ikeda F, Santantonio TA, Habersetzer F, Ramji A, Lau AH, Suri V, Flaherty JF, Wang H, Gaggar A, Subramanian GM, Mukewar S, Brunetto MR, Fung S, Chan HL.

Clin Gastroenterol Hepatol. 2018 Jun 20. pii: S1542-3565(18)30633-5. doi: 10.1016/j.cgh.2018.06.023. [Epub ahead of print]


Role of serum M2BPGi levels on diagnosing significant liver fibrosis and cirrhosis in treated patients with chronic hepatitis B virus infection.

Mak LY, Wong DK, Cheung KS, Seto WK, Lai CL, Yuen MF.

Clin Transl Gastroenterol. 2018 Jun 19;9(6):163. doi: 10.1038/s41424-018-0020-9.


Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.

Sawai H, Nishida N, Khor SS, Honda M, Sugiyama M, Baba N, Yamada K, Sawada N, Tsugane S, Koike K, Kondo Y, Yatsuhashi H, Nagaoka S, Taketomi A, Fukai M, Kurosaki M, Izumi N, Kang JH, Murata K, Hino K, Nishina S, Matsumoto A, Tanaka E, Sakamoto N, Ogawa K, Yamamoto K, Tamori A, Yokosuka O, Kanda T, Sakaida I, Itoh Y, Eguchi Y, Oeda S, Mochida S, Yuen MF, Seto WK, Poovorawan Y, Posuwan N, Mizokami M, Tokunaga K.

Sci Rep. 2018 May 21;8(1):7958. doi: 10.1038/s41598-018-26217-7.


96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection.

Agarwal K, Brunetto M, Seto WK, Lim YS, Fung S, Marcellin P, Ahn SH, Izumi N, Chuang WL, Bae H, Sharma M, Janssen HLA, Pan CQ, Çelen MK, Furusyo N, Shalimar D, Yoon KT, Trinh H, Flaherty JF, Gaggar A, Lau AH, Cathcart AL, Lin L, Bhardwaj N, Suri V, Mani Subramanian G, Gane EJ, Buti M, Chan HLY; GS-US-320-0110; GS-US-320-0108 Investigators.

J Hepatol. 2018 Apr;68(4):672-681. doi: 10.1016/j.jhep.2017.11.039. Epub 2018 Jan 17.


An update on the toxicological considerations for protease inhibitors used for hepatitis C infection.

Mak LY, Seto WK, Lai CL, Yuen MF.

Expert Opin Drug Metab Toxicol. 2018 May;14(5):483-491. doi: 10.1080/17425255.2018.1472236. Epub 2018 May 7. Review.


Magnetic resonance cholangiogram patterns and clinical profiles of ketamine-related cholangiopathy in drug users.

Seto WK, Mak SK, Chiu K, Vardhanabhuti V, Wong HF, Leong HT, Lee PSF, Ho YC, Lee CK, Cheung KS, Yuen MF, Leung WK.

J Hepatol. 2018 Jul;69(1):121-128. doi: 10.1016/j.jhep.2018.03.006. Epub 2018 Mar 16.


Long-term outcomes and predictive scores for hepatocellular carcinoma and hepatitis B surface antigen seroclearance after hepatitis B e-antigen seroclearance.

Fung J, Cheung KS, Wong DK, Mak LY, To WP, Seto WK, Lai CL, Yuen MF.

Hepatology. 2018 Aug;68(2):462-472. doi: 10.1002/hep.29874. Epub 2018 Jun 6.


Aspirin and Risk of Gastric Cancer After Helicobacter pylori Eradication: A Territory-Wide Study.

Cheung KS, Chan EW, Wong AYS, Chen L, Seto WK, Wong ICK, Leung WK.

J Natl Cancer Inst. 2018 Jul 1;110(7):743-749. doi: 10.1093/jnci/djx267.


Review article: long-term safety of oral anti-viral treatment for chronic hepatitis B.

Wong GL, Seto WK, Wong VW, Yuen MF, Chan HL.

Aliment Pharmacol Ther. 2018 Mar;47(6):730-737. doi: 10.1111/apt.14497. Epub 2018 Jan 22. Review.


Impact of antibiotic stewardship programmes in Asia: a systematic review and meta-analysis.

Lee CF, Cowling BJ, Feng S, Aso H, Wu P, Fukuda K, Seto WH.

J Antimicrob Chemother. 2018 Apr 1;73(4):844-851. doi: 10.1093/jac/dkx492.


Prolonged Dexmedetomidine Infusion and Drug Withdrawal In Critically Ill Children.

Haenecour AS, Seto W, Urbain CM, Stephens D, Laussen PC, Balit CR.

J Pediatr Pharmacol Ther. 2017 Nov-Dec;22(6):453-460. doi: 10.5863/1551-6776-22.6.453.


Pharmacokinetic evaluation of besifovir for the treatment of HBV infection.

Mak LY, Seto WK, Lai CL, Yuen MF.

Expert Opin Drug Metab Toxicol. 2018 Jan;14(1):101-106. doi: 10.1080/17425255.2018.1417983. Epub 2017 Dec 18. Review.


Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis.

Cheung KS, Seto WK, Fung J, Mak LY, Lai CL, Yuen MF.

World J Gastroenterol. 2017 Nov 28;23(44):7863-7874. doi: 10.3748/wjg.v23.i44.7863.


Epidemiology and natural history of Wilson's disease in the Chinese: A territory-based study in Hong Kong between 2000 and 2016.

Cheung KS, Seto WK, Fung J, Mak LY, Lai CL, Yuen MF.

World J Gastroenterol. 2017 Nov 21;23(43):7716-7726. doi: 10.3748/wjg.v23.i43.7716.


Seven-Year Treatment Outcome of Entecavir in a Real-World Cohort: Effects on Clinical Parameters, HBsAg and HBcrAg Levels.

Lam YF, Seto WK, Wong D, Cheung KS, Fung J, Mak LY, Yuen J, Chong CK, Lai CL, Yuen MF.

Clin Transl Gastroenterol. 2017 Oct 26;8(10):e125. doi: 10.1038/ctg.2017.51.


Hepatitis B core protein as a therapeutic target.

Mak LY, Wong DK, Seto WK, Lai CL, Yuen MF.

Expert Opin Ther Targets. 2017 Dec;21(12):1153-1159. doi: 10.1080/14728222.2017.1397134. Epub 2017 Nov 1. Review.


Review article: hepatitis B core-related antigen (HBcrAg): an emerging marker for chronic hepatitis B virus infection.

Mak LY, Wong DK, Cheung KS, Seto WK, Lai CL, Yuen MF.

Aliment Pharmacol Ther. 2018 Jan;47(1):43-54. doi: 10.1111/apt.14376. Epub 2017 Oct 16. Review.


Association Between Hepatic Steatosis, Measured by Controlled Attenuation Parameter, and Fibrosis Burden in Chronic Hepatitis B.

Seto WK, Hui RWH, Mak LY, Fung J, Cheung KS, Liu KSH, Wong DK, Lai CL, Yuen MF.

Clin Gastroenterol Hepatol. 2018 Apr;16(4):575-583.e2. doi: 10.1016/j.cgh.2017.09.044. Epub 2017 Sep 29.


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