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Proteomics, glycomics, and glycoproteomics of matrisome molecules.

Raghunathan R, Sethi MK, Klein JA, Zaia J.

Mol Cell Proteomics. 2019 Aug 30. pii: mcp.R119.001543. doi: 10.1074/mcp.R119.001543. [Epub ahead of print] Review.


Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers.

Chatterjee S, Lee LY, Kawahara R, Abrahams JL, Adamczyk B, Anugraham M, Ashwood C, Sumer-Bayraktar Z, Briggs MT, Chik JHL, Everest-Dass A, Förster S, Hinneburg H, Leite KRM, Loke I, Möginger U, Moh ESX, Nakano M, Recuero S, Sethi MK, Srougi M, Stavenhagen K, Venkatakrishnan V, Wongtrakul-Kish K, Diestel S, Hoffmann P, Karlsson NG, Kolarich D, Molloy MP, Muders MH, Oehler MK, Packer NH, Palmisano G, Thaysen-Andersen M.

Proteomics. 2019 Aug 16:e1900010. doi: 10.1002/pmic.201900010. [Epub ahead of print]


Association Between 6-Week Postdischarge Risk Classification and 12-Month Outcomes After Orthopedic Trauma.

Castillo RC, Huang Y, Scharfstein D, Frey K, Bosse MJ, Pollak AN, Vallier HA, Archer KR, Hymes RA, Newcomb AB, MacKenzie EJ, Wegener S; and the Major Extremity Trauma Research Consortium (METRC), Hsu JR, Karunakar MA, Seymour RB, Sims SH, Flores E, Churchill C, Hak DJ, Henderson CE, Mir HR, Chan DS, Shah AR, Steverson B, Westberg J, Gary JL, Achor TS, Choo A, Munz JW, Porrey M, Hendrickson S, Breslin MA, McKinley TO, Gaski GE, Kempton LB, Sorkin AT, Virkus WW, Hill LC, Jones CB, Sietsema DL, O'Toole RV, Ordonio K, Howe AL, Zerhusen TJ Jr, Obremskey W, Boyce RH, Jahangir AA, Molina CS, Sethi MK, Vanston SW, Carroll EA, Drye DY, Holden MB, Collins SC, Wysocki E.

JAMA Surg. 2019 Feb 1;154(2):e184824. doi: 10.1001/jamasurg.2018.4824. Epub 2019 Feb 20.


Management of Femoral Defects Greater Than 5 cm Following Open Femur Fractures: A 12-Year Retrospective Review.

Attum B, Douleh DG, Whiting PS, Dodd AC, Shen MS, Lakomkin N, Obremskey WT, Sethi MK.

J Surg Orthop Adv. Fall 2018;27(3):203-208.


Are Cardiac Complications Associated With Other Adverse Events? A Look at 56,000 Orthopaedic Trauma Patients.

Yarlagadda M, Shen M, Abraham A, Mousavi I, Sethi MK.

J Surg Orthop Adv. Fall 2018;27(3):198-202.


Sensitized genetic backgrounds reveal differential roles for EGF repeat xylosyltransferases in Drosophila Notch signaling.

Pandey A, Li-Kroeger D, Sethi MK, Lee TV, Buettner FF, Bakker H, Jafar-Nejad H.

Glycobiology. 2018 Nov 1;28(11):849-859. doi: 10.1093/glycob/cwy080.


The risk of deep vein thrombosis in total joint patients compared to orthopaedic trauma patients: Need for new prevention guidelines.

Shen M, Cutrera NJ, Dodd AC, Wallace C, Avilucea FR, Melbourne C, Jahangir AA, Mir HH, Obremskey WT, Sethi MK.

J Clin Orthop Trauma. 2017 Nov;8(Suppl 2):S52-S56. doi: 10.1016/j.jcot.2016.12.007. Epub 2017 Jan 10.


Open treatment of ankle fracture as inpatient increases risk of complication.

Shen MS, Dodd AC, Lakomkin N, Mousavi I, Bulka C, Jahangir AA, Sethi MK.

J Orthop Traumatol. 2017 Dec;18(4):431-438. doi: 10.1007/s10195-017-0472-9. Epub 2017 Oct 26.


Heparan sulfate: Resilience factor and therapeutic target for cocaine abuse.

Chen J, Kawamura T, Sethi MK, Zaia J, Repunte-Canonigo V, Sanna PP.

Sci Rep. 2017 Oct 24;7(1):13931. doi: 10.1038/s41598-017-13960-6.


Opioid Prescribing Practices by Orthopaedic Trauma Surgeons After Isolated Femur Fractures.

Attum B, Rodriguez-Buitrago A, Harrison N, Evans A, Obremskey W, Sethi MK, Jahangir AA.

J Orthop Trauma. 2018 Mar;32(3):e106-e111. doi: 10.1097/BOT.0000000000001046.


Patients at Increased Risk of Major Adverse Events Following Operative Treatment of Distal Radius Fractures: Inpatient versus Outpatient.

Whiting PS, Rice CD, Avilucea FR, Bulka CM, Shen MS, Obremskey WT, Sethi MK.

J Wrist Surg. 2017 Aug;6(3):220-226. doi: 10.1055/s-0037-1599216. Epub 2017 Mar 6.


Outcomes of Distal Femur Nonunions Treated With a Combined Nail/Plate Construct and Autogenous Bone Grafting.

Attum B, Douleh D, Whiting PS, White-Dzuro GA, Dodd AC, Shen MS, Mir HR, Obremskey WT, Sethi MK.

J Orthop Trauma. 2017 Sep;31(9):e301-e304. doi: 10.1097/BOT.0000000000000926.


Damage Control Plating in Open Tibial Shaft Fractures: A Cheaper and Equally Effective Alternative to Spanning External Fixation.

Whiting PS, Mitchell PM, Perdue AM, Silverberg AJ, Greenberg SE, Thakore RV, Sathiyakumar V, Mir HR, Obremskey WT, Sethi MK.

J Surg Orthop Adv. Summer 2017;26(2):86-93.


Does Physician Reimbursement Correlate to Risk in Orthopaedic Trauma?

Sathiyakumar V, Thakore RV, Molina CS, Obremskey WT, Sethi MK.

J Surg Orthop Adv. 2017 Spring;26(1):48-53.


Drivers of hospital length of stay in 56,000 orthopaedic trauma patients: The impact of postoperative cardiac events.

Douleh DG, Yarlagadda M, Shen MS, Williams G, Mousavi I, Sethi MK.

J Clin Orthop Trauma. 2017 Jan-Mar;8(1):45-49. doi: 10.1016/j.jcot.2017.02.003. Epub 2017 Feb 9.


Integrated Proteomic and Transcriptomic-Based Approaches to Identifying Signature Biomarkers and Pathways for Elucidation of Daoy and UW228 Subtypes.

Higdon R, Kala J, Wilkins D, Yan JF, Sethi MK, Lin L, Liu S, Montague E, Janko I, Choiniere J, Kolker N, Hancock WS, Kolker E, Fanayan S.

Proteomes. 2017 Feb 3;5(1). pii: E5. doi: 10.3390/proteomes5010005.


Predicting the post-operative length of stay for the orthopaedic trauma patient.

Chona D, Lakomkin N, Bulka C, Mousavi I, Kothari P, Dodd AC, Shen MS, Obremskey WT, Sethi MK.

Int Orthop. 2017 May;41(5):859-868. doi: 10.1007/s00264-017-3425-2. Epub 2017 Feb 21.


Outcomes of Distal Femur Nonunions Treated with a Combined Nail/Plate Construct and Autogenous Bone Grafting.

Attum B, Douleh D, Whiting PS, White-Dzuro GA, Dodd AC, Shen MS, Obremskey WT, Sethi MK.

J Orthop Trauma. 2016 Dec 26. doi: 10.1097/BOT.0000000000000776. [Epub ahead of print]


VH1 Family Immunoglobulin Repertoire Sequencing after Allogeneic Hematopoietic Stem Cell Transplantation.

Sethi MK, Thol F, Stadler M, Heuser M, Ganser A, Koenecke C, Pabst O.

PLoS One. 2017 Jan 17;12(1):e0168096. doi: 10.1371/journal.pone.0168096. eCollection 2017.


The impact of resident involvement on outcomes in orthopedic trauma: An analysis of 20,090 cases.

Mitchell PM, Gavrilova SA, Dodd AC, Attum B, Obremskey WT, Sethi MK.

J Clin Orthop Trauma. 2016 Oct-Dec;7(4):229-233. Epub 2016 Jun 11.


Incidence and predictive risk factors of postoperative sepsis in orthopedic trauma patients.

Lakomkin N, Sathiyakumar V, Wick B, Shen MS, Jahangir AA, Mir H, Obremskey WT, Dodd AC, Sethi MK.

J Orthop Traumatol. 2017 Jun;18(2):151-158. doi: 10.1007/s10195-016-0437-4. Epub 2016 Nov 15.


Identifying N-Glycan Biomarkers in Colorectal Cancer by Mass Spectrometry.

Sethi MK, Hancock WS, Fanayan S.

Acc Chem Res. 2016 Oct 18;49(10):2099-2106. Epub 2016 Sep 21. Review.


Corrigendum to "Adverse cardiac events in 56,000 orthopaedic trauma patients: Does anatomic area make a difference?" [Injury 47 (2016) 1856-1861].

Lee AK, Dodd AC, Lakomkin N, Yarlagadda M, Jahangir AA, Collinge CA, Sethi MK.

Injury. 2016 Dec;47(12):2838-2840. doi: 10.1016/j.injury.2016.09.035. Epub 2016 Oct 5. No abstract available.


The Gustilo-Anderson classification system as predictor of nonunion and infection in open tibia fractures.

Thakore RV, Francois EL, Nwosu SK, Attum B, Whiting PS, Siuta MA, Benvenuti MA, Smith AK, Shen MS, Mousavi I, Obremskey WT, Sethi MK.

Eur J Trauma Emerg Surg. 2017 Oct;43(5):651-656. doi: 10.1007/s00068-016-0725-y. Epub 2016 Sep 22.


Higher Charlson Comorbidity Index Scores Are Associated With Increased Hospital Length of Stay After Lower Extremity Orthopaedic Trauma.

Lakomkin N, Kothari P, Dodd AC, VanHouten JP, Yarlagadda M, Collinge CA, Obremskey WT, Sethi MK.

J Orthop Trauma. 2017 Jan;31(1):21-26. doi: 10.1097/BOT.0000000000000701.


Extracellular matrix proteomics in schizophrenia and Alzheimer's disease.

Sethi MK, Zaia J.

Anal Bioanal Chem. 2017 Jan;409(2):379-394. doi: 10.1007/s00216-016-9900-6. Epub 2016 Sep 6. Review.


American Society of Anesthesiologists Score as a Predictive Tool to Optimize Blood Ordering for Intraoperative Transfusion in Orthopaedic Trauma Cases.

Sathiyakumar V, Estevez-Ordonez D, Thakore RV, Lee YM, Ehrenfeld JM, Obremskey WT, Sethi MK.

J Surg Orthop Adv. 2016 summer;25(2):105-9.


Predictors of 30-day mortality following hip/pelvis fractures.

Dodd AC, Bulka C, Jahangir A, Mir HR, Obremskey WT, Sethi MK.

Orthop Traumatol Surg Res. 2016 Oct;102(6):707-10. doi: 10.1016/j.otsr.2016.05.016. Epub 2016 Aug 3.


Geographic variations in orthopedic trauma billing and reimbursements for hip and pelvis fractures in the Medicare population.

Dodd AC, Lakomkin N, Bulka C, Thakore R, Collinge CA, Sethi MK.

J Orthop. 2016 Jun 25;13(4):264-7. doi: 10.1016/j.jor.2016.06.015. eCollection 2016 Dec.


Adverse cardiac events in 56,000 orthopaedic trauma patients: Does anatomic area make a difference?

Lee AK, Dodd AC, Lakomkin N, Yarlagadda M, Jahangir AA, Collinge CA, Sethi MK.

Injury. 2016 Aug;47(8):1856-61. doi: 10.1016/j.injury.2016.06.013. Epub 2016 Jun 8. Erratum in: Injury. 2016 Dec;47(12 ):2838-2840.


Increased risk of adverse events in management of femur and tibial shaft fractures with plating: An analysis of NSQIP data.

Dodd AC, Salib CG, Lakomkin N, Obremskey WT, Sethi MK.

J Clin Orthop Trauma. 2016 Apr-Jun;7(2):80-5. doi: 10.1016/j.jcot.2016.01.002. Epub 2016 Mar 7.


Risk Factors for Deep Venous Thrombosis Following Orthopaedic Trauma Surgery: An Analysis of 56,000 patients.

Whiting PS, White-Dzuro GA, Greenberg SE, VanHouten JP, Avilucea FR, Obremskey WT, Sethi MK.

Arch Trauma Res. 2016 Jan 23;5(1):e32915. doi: 10.5812/atr.32915. eCollection 2016 Mar.


Predictors of Adverse Events for Ankle Fractures: An Analysis of 6800 Patients.

Dodd AC, Lakomkin N, Attum B, Bulka C, Karhade AV, Douleh DG, Mir H, Jahangir AA, Obremskey WT, Sethi MK.

J Foot Ankle Surg. 2016 Jul-Aug;55(4):762-6. doi: 10.1053/j.jfas.2016.03.010. Epub 2016 Apr 14.


Locking Versus Nonlocking Implants in Isolated Lower Extremity Fractures: Analysis of Cost and Complications.

An TJ, Thakore RV, Greenberg SE, Sathiyakumar V, Kay HF, Gerasimopoulos M, Obremskey WT, Sethi MK.

J Surg Orthop Adv. 2016 Spring;25(1):49-53.


Staged Columnar Fixation of Bicondylar Tibial Plateaus: A Cheaper Alternative to External Fixation.

Perdue A, Greenberg SE, Sathiyakumar V, Thakore RV, Mir HR, Obremskey WT, Sethi MK.

J Surg Orthop Adv. 2016 Spring;25(1):13-7.


Pre-operative labs: Wasted dollars or predictors of post-operative cardiac and septic events in orthopaedic trauma patients?

Lakomkin N, Sathiyakumar V, Dodd AC, Jahangir AA, Whiting PS, Obremskey WT, Sethi MK.

Injury. 2016 Jun;47(6):1217-21. doi: 10.1016/j.injury.2016.03.004. Epub 2016 Mar 11.


Do orthopaedic trauma patients develop higher rates of cardiac complications? An analysis of 56,000 patients.

Dodd AC, Lakomkin N, Sathiyakumar V, Obremskey WT, Sethi MK.

Eur J Trauma Emerg Surg. 2017 Jun;43(3):329-336. doi: 10.1007/s00068-016-0649-6. Epub 2016 Feb 23.


In response.

Greenberg SE, Lakomkin N, VanHouten JP, Sethi MK.

J Orthop Trauma. 2016 Mar;30(3):e110. doi: 10.1097/ No abstract available.


Body mass index predicts perioperative complications following orthopaedic trauma surgery: an ACS-NSQIP analysis.

Whiting PS, White-Dzuro GA, Avilucea FR, Dodd AC, Lakomkin N, Obremskey WT, Collinge CA, Sethi MK.

Eur J Trauma Emerg Surg. 2017 Apr;43(2):255-264. doi: 10.1007/s00068-016-0642-0. Epub 2016 Feb 15.


Mass Spectrometry-Based N-Glycomics of Colorectal Cancer.

Sethi MK, Fanayan S.

Int J Mol Sci. 2015 Dec 9;16(12):29278-304. doi: 10.3390/ijms161226165. Review.


Risk factors for discharge to rehabilitation among hip fracture patients.

Sathiyakumar V, Thakore R, Greenberg SE, Dodd AC, Obremskey W, Sethi MK.

Am J Orthop (Belle Mead NJ). 2015 Nov;44(11):E438-43.


Surgical site infection in orthopedic trauma: A case-control study evaluating risk factors and cost.

Thakore RV, Greenberg SE, Shi H, Foxx AM, Francois EL, Prablek MA, Nwosu SK, Archer KR, Ehrenfeld JM, Obremskey WT, Sethi MK.

J Clin Orthop Trauma. 2015 Dec;6(4):220-6. doi: 10.1016/j.jcot.2015.04.004. Epub 2015 Jun 18.


Heterotopic ossification after hemiarthroplasty of the hip - A comparison of three common approaches.

Corrigan CM, Greenberg SE, Sathiyakumar V, Mitchell PM, Francis A, Omar A, Thakore RV, Obremskey WT, Sethi MK.

J Clin Orthop Trauma. 2015 Mar;6(1):1-5. doi: 10.1016/j.jcot.2014.11.004. Epub 2014 Dec 26.


Do Politics Matter to an Orthopaedic Surgeon? (They Should!).

Lee AK, Sethi MK.

J Orthop Trauma. 2015 Nov;29 Suppl 11:S3-4. doi: 10.1097/BOT.0000000000000428. Review.


Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues.

Yan JF, Kim H, Jeong SK, Lee HJ, Sethi MK, Lee LY, Beavis RC, Im H, Snyder MP, Hofree M, Ideker T, Wu SL, Paik YK, Fanayan S, Hancock WS.

J Proteome Res. 2015 Dec 4;14(12):4995-5006. doi: 10.1021/acs.jproteome.5b00827. Epub 2015 Oct 20.


Invited Commentary.

Sethi MK, Mir HR.

J Orthop Trauma. 2015 Oct;29(10):462-3. doi: 10.1097/BOT.0000000000000375. No abstract available.


Isolated sacral injuries: Postoperative length of stay, complications, and readmission.

Sathiyakumar V, Shi H, Thakore RV, Lee YM, Joyce D, Ehrenfeld J, Obremskey WT, Sethi MK.

World J Orthop. 2015 Sep 18;6(8):629-35. doi: 10.5312/wjo.v6.i8.629. eCollection 2015 Sep 18.


Does Admission to Medicine or Orthopaedics Impact a Geriatric Hip Patient's Hospital Length of Stay?

Greenberg SE, VanHouten JP, Lakomkin N, Ehrenfeld J, Jahangir AA, Boyce RH, Obremksey WT, Sethi MK.

J Orthop Trauma. 2016 Feb;30(2):95-9. doi: 10.1097/BOT.0000000000000440.


BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity.

Fransen F, Zagato E, Mazzini E, Fosso B, Manzari C, El Aidy S, Chiavelli A, D'Erchia AM, Sethi MK, Pabst O, Marzano M, Moretti S, Romani L, Penna G, Pesole G, Rescigno M.

Immunity. 2015 Sep 15;43(3):527-40. doi: 10.1016/j.immuni.2015.08.011. Epub 2015 Sep 8.

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