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Items: 1 to 50 of 619

1.

Serological and molecular detection of Mycoplasma pneumoniae in children with community-acquired lower respiratory tract infections.

Kumar S, Garg IB, Sethi GR.

Diagn Microbiol Infect Dis. 2019 Mar 27. pii: S0732-8893(18)30715-6. doi: 10.1016/j.diagmicrobio.2019.03.010. [Epub ahead of print]

PMID:
31097260
2.

Focus on Formononetin: Anticancer Potential and Molecular Targets.

Ong SKL, Shanmugam MK, Fan L, Fraser SE, Arfuso F, Ahn KS, Sethi G, Bishayee A.

Cancers (Basel). 2019 May 1;11(5). pii: E611. doi: 10.3390/cancers11050611. Review.

3.

Brassinin Represses Invasive Potential of Lung Carcinoma Cells through Deactivation of PI3K/Akt/mTOR Signaling Cascade.

Yang MH, Lee JH, Ko JH, Jung SH, Sethi G, Ahn KS.

Molecules. 2019 Apr 22;24(8). pii: E1584. doi: 10.3390/molecules24081584.

4.

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets.

Banik K, Ranaware AM, Deshpande V, Nalawade SP, Padmavathi G, Bordoloi D, Sailo BL, Shanmugam MK, Fan L, Arfuso F, Sethi G, Kunnumakkara AB.

Pharmacol Res. 2019 Apr 17;144:192-209. doi: 10.1016/j.phrs.2019.04.004. [Epub ahead of print] Review.

PMID:
31002949
5.

Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells.

Hwang ST, Kim C, Lee JH, Chinnathambi A, Alharbi SA, Shair OHM, Sethi G, Ahn KS.

Phytomedicine. 2019 Mar 31;59:152907. doi: 10.1016/j.phymed.2019.152907. [Epub ahead of print]

PMID:
30981183
6.

PARP inhibition by olaparib alleviates chronic asthma-associated remodeling features via modulating inflammasome signaling in mice.

Sethi GS, Sharma S, Naura AS.

IUBMB Life. 2019 Apr 9. doi: 10.1002/iub.2048. [Epub ahead of print]

PMID:
30964965
7.

Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential.

Varughese RS, Lam WS, Marican AABH, Viganeshwari SH, Bhave AS, Syn NL, Wang J, Wong AL, Kumar AP, Lobie PE, Lee SC, Sethi G, Goh BC, Wang L.

Cancer. 2019 Jun 1;125(11):1789-1798. doi: 10.1002/cncr.32069. Epub 2019 Apr 1. Review.

PMID:
30933320
8.

Association of Fecal Microflora with Bronchiolitis.

Rai S, Kaur A, Sethi GK, Goyal J, Kaur S, Arora H.

Indian J Pediatr. 2019 Mar 30. doi: 10.1007/s12098-019-02929-0. [Epub ahead of print] No abstract available.

PMID:
30927139
9.

Role of Natural Products in Modulating Histone Deacetylases in Cancer.

Merarchi M, Sethi G, Shanmugam MK, Fan L, Arfuso F, Ahn KS.

Molecules. 2019 Mar 16;24(6). pii: E1047. doi: 10.3390/molecules24061047. Review.

10.

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases.

Mishra S, Verma SS, Rai V, Awasthee N, Chava S, Hui KM, Kumar AP, Challagundla KB, Sethi G, Gupta SC.

Cell Mol Life Sci. 2019 May;76(10):1947-1966. doi: 10.1007/s00018-019-03053-0. Epub 2019 Mar 16. Review.

PMID:
30879091
11.

Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases.

Yang MH, Jung SH, Sethi G, Ahn KS.

Molecules. 2019 Mar 12;24(5). pii: E995. doi: 10.3390/molecules24050995. Review.

12.

Conditioned media from adipocytes promote proliferation, migration, and invasion in melanoma and colorectal cancer cells.

Ko JH, Um JY, Lee SG, Yang WM, Sethi G, Ahn KS.

J Cell Physiol. 2019 Mar 9. doi: 10.1002/jcp.28456. [Epub ahead of print]

PMID:
30851074
13.

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication.

Loh CY, Arya A, Naema AF, Wong WF, Sethi G, Looi CY.

Front Oncol. 2019 Feb 21;9:48. doi: 10.3389/fonc.2019.00048. eCollection 2019. Review.

14.

Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade.

Lee JH, Kim C, Um JY, Sethi G, Ahn KS.

Cancers (Basel). 2019 Feb 22;11(2). pii: E254. doi: 10.3390/cancers11020254.

15.

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

Sailo BL, Banik K, Girisa S, Bordoloi D, Fan L, Halim CE, Wang H, Kumar AP, Zheng D, Mao X, Sethi G, Kunnumakkara AB.

Cancers (Basel). 2019 Feb 19;11(2). pii: E246. doi: 10.3390/cancers11020246. Review.

16.

Potential of Zerumbone as an Anti-Cancer Agent.

Girisa S, Shabnam B, Monisha J, Fan L, Halim CE, Arfuso F, Ahn KS, Sethi G, Kunnumakkara AB.

Molecules. 2019 Feb 18;24(4). pii: E734. doi: 10.3390/molecules24040734. Review.

17.

Targeting autophagy using natural compounds for cancer prevention and therapy.

Deng S, Shanmugam MK, Kumar AP, Yap CT, Sethi G, Bishayee A.

Cancer. 2019 Apr 15;125(8):1228-1246. doi: 10.1002/cncr.31978. Epub 2019 Feb 12. Review.

PMID:
30748003
18.

Encapsulated human mesenchymal stem cells (eMSCs) as a novel anti-cancer agent targeting breast cancer stem cells: Development of 3D primed therapeutic MSCs.

Mandal S, Arfuso F, Sethi G, Dharmarajan A, Warrier S.

Int J Biochem Cell Biol. 2019 May;110:59-69. doi: 10.1016/j.biocel.2019.02.001. Epub 2019 Feb 6.

PMID:
30735730
19.

Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis.

Liu Y, Xu X, Lin P, He Y, Zhang Y, Cao B, Zhang Z, Sethi G, Liu J, Zhou X, Mao X.

J Biol Chem. 2019 Mar 22;294(12):4572-4582. doi: 10.1074/jbc.RA118.006057. Epub 2019 Feb 4.

PMID:
30718275
20.

Molecular Mechanisms of Action of Tocotrienols in Cancer: Recent Trends and Advancements.

Aggarwal V, Kashyap D, Sak K, Tuli HS, Jain A, Chaudhary A, Garg VK, Sethi G, Yerer MB.

Int J Mol Sci. 2019 Feb 2;20(3). pii: E656. doi: 10.3390/ijms20030656. Review.

21.

Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells.

Lee JH, Kim C, Lee J, Um JY, Sethi G, Ahn KS.

Phytomedicine. 2019 Mar 1;55:282-292. doi: 10.1016/j.phymed.2018.06.038. Epub 2018 Aug 11.

PMID:
30668440
22.

Identifying Pathways Mediating Obstructive Sleep Apnea and Obesity in Indian Children.

Lorenzoni G, Azzolina D, Sethi G, Manchanda S, Gregori D, Gulati A, Baldi I.

Indian J Pediatr. 2019 Jan;86(Suppl 1):15-19. doi: 10.1007/s12098-018-2828-4. Epub 2019 Jan 19.

PMID:
30661192
23.

The expanding roles of long non-coding RNAs in the regulation of cancer stem cells.

Ma Z, Wang YY, Xin HW, Wang L, Arfuso F, Dharmarajan A, Kumar AP, Wang H, Tang FR, Warrier S, Tergaonkar V, Sethi G.

Int J Biochem Cell Biol. 2019 Mar;108:17-20. doi: 10.1016/j.biocel.2019.01.003. Epub 2019 Jan 7.

PMID:
30630112
24.

Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model.

Jung YY, Shanmugam MK, Narula AS, Kim C, Lee JH, Namjoshi OA, Blough BE, Sethi G, Ahn KS.

Cancers (Basel). 2019 Jan 7;11(1). pii: E49. doi: 10.3390/cancers11010049.

25.

Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection.

Peng XC, Huang JR, Wang SW, Liu L, Liu ZZ, Sethi G, Ren BX, Tang FR.

Evid Based Complement Alternat Med. 2018 Nov 26;2018:2767208. doi: 10.1155/2018/2767208. eCollection 2018. Review.

26.

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors.

Lee M, Hirpara JL, Eu JQ, Sethi G, Wang L, Goh BC, Wong AL.

Redox Biol. 2018 Dec 13:101073. doi: 10.1016/j.redox.2018.101073. [Epub ahead of print] Review.

27.

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma.

Bhuvanalakshmi G, Gamit N, Patil M, Arfuso F, Sethi G, Dharmarajan A, Kumar AP, Warrier S.

Cancers (Basel). 2018 Dec 27;11(1). pii: E25. doi: 10.3390/cancers11010025.

28.

Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis.

Shanmugam MK, Ahn KS, Hsu A, Woo CC, Yuan Y, Tan KHB, Chinnathambi A, Alahmadi TA, Alharbi SA, Koh APF, Arfuso F, Huang RY, Lim LHK, Sethi G, Kumar AP.

Front Pharmacol. 2018 Dec 4;9:1294. doi: 10.3389/fphar.2018.01294. eCollection 2018.

29.

Pharmacological Utilization of Bergamottin, Derived from Grapefruits, in Cancer Prevention and Therapy.

Ko JH, Arfuso F, Sethi G, Ahn KS.

Int J Mol Sci. 2018 Dec 14;19(12). pii: E4048. doi: 10.3390/ijms19124048. Review.

30.

Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics.

Praharaj PP, Naik PP, Panigrahi DP, Bhol CS, Mahapatra KK, Patra S, Sethi G, Bhutia SK.

Cell Mol Life Sci. 2019 May;76(9):1641-1652. doi: 10.1007/s00018-018-2990-x. Epub 2018 Dec 11. Review.

PMID:
30539200
31.

Mycoplasma pneumoniae infection and asthma in children.

Kumar S, Roy RD, Sethi GR, Saigal SR.

Trop Doct. 2019 Apr;49(2):117-119. doi: 10.1177/0049475518816591. Epub 2018 Dec 11.

PMID:
30537911
32.

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.

Lee JH, Kim C, Ko JH, Jung YY, Jung SH, Kim E, Kong M, Chinnathambi A, Alahmadi TA, Alharbi SA, Sethi G, Ahn KS.

J Cell Biochem. 2019 Jun;120(6):9787-9798. doi: 10.1002/jcb.28259. Epub 2018 Dec 5.

PMID:
30520154
33.

Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance.

Raghunath A, Sundarraj K, Arfuso F, Sethi G, Perumal E.

Cancers (Basel). 2018 Dec 3;10(12). pii: E481. doi: 10.3390/cancers10120481. Review.

34.

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway.

Mohan CD, Bharathkumar H, Dukanya, Rangappa S, Shanmugam MK, Chinnathambi A, Alharbi SA, Alahmadi TA, Bhattacharjee A, Lobie PE, Deivasigamani A, Hui KM, Sethi G, Basappa, Rangappa KS, Kumar AP.

Front Pharmacol. 2018 Nov 5;9:1125. doi: 10.3389/fphar.2018.01125. eCollection 2018.

35.

Role of tumor-derived exosomes in cancer metastasis.

Wee I, Syn N, Sethi G, Goh BC, Wang L.

Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):12-19. doi: 10.1016/j.bbcan.2018.10.004. Epub 2018 Nov 9. Review.

PMID:
30419312
36.

A Review on Liquid Chromatography-Tandem Mass Spectrometry Methods for Rapid Quantification of Oncology Drugs.

Wong AL, Xiang X, Ong PS, Mitchell EQY, Syn N, Wee I, Kumar AP, Yong WP, Sethi G, Goh BC, Ho PC, Wang L.

Pharmaceutics. 2018 Nov 8;10(4). pii: E221. doi: 10.3390/pharmaceutics10040221. Review.

37.

Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma.

Lee JH, Kim C, Lee SG, Sethi G, Ahn KS.

Cancers (Basel). 2018 Nov 8;10(11). pii: E427. doi: 10.3390/cancers10110427.

38.

Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol.

Jung YY, Hwang ST, Sethi G, Fan L, Arfuso F, Ahn KS.

Molecules. 2018 Oct 31;23(11). pii: E2827. doi: 10.3390/molecules23112827. Review.

39.

Molecular Targets Modulated by Fangchinoline in Tumor Cells and Preclinical Models.

Mérarchi M, Sethi G, Fan L, Mishra S, Arfuso F, Ahn KS.

Molecules. 2018 Oct 5;23(10). pii: E2538. doi: 10.3390/molecules23102538. Review.

PMID:
30301146
Free PMC Article
40.

TIPE Family of Proteins and Its Implications in Different Chronic Diseases.

Bordoloi D, Banik K, Shabnam B, Padmavathi G, Monisha J, Arfuso F, Dharmarajan A, Mao X, Lim LHK, Wang L, Fan L, Hui KM, Kumar AP, Sethi G, Kunnumakkara AB.

Int J Mol Sci. 2018 Sep 29;19(10). pii: E2974. doi: 10.3390/ijms19102974. Review.

41.

Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells.

Liu L, Ahn KS, Shanmugam MK, Wang H, Shen H, Arfuso F, Chinnathambi A, Alharbi SA, Chang Y, Sethi G, Tang FR.

J Cell Biochem. 2019 Mar;120(3):4504-4513. doi: 10.1002/jcb.27738. Epub 2018 Sep 27.

PMID:
30260018
42.

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies.

Arora L, Kumar AP, Arfuso F, Chng WJ, Sethi G.

Cancers (Basel). 2018 Sep 13;10(9). pii: E327. doi: 10.3390/cancers10090327. Review.

43.

Sorcin a Potential Molecular Target for Cancer Therapy.

Shabnam B, Padmavathi G, Banik K, Girisa S, Monisha J, Sethi G, Fan L, Wang L, Mao X, Kunnumakkara AB.

Transl Oncol. 2018 Dec;11(6):1379-1389. doi: 10.1016/j.tranon.2018.08.015. Epub 2018 Sep 11. Review.

44.

Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer.

Ranaware AM, Banik K, Deshpande V, Padmavathi G, Roy NK, Sethi G, Fan L, Kumar AP, Kunnumakkara AB.

Int J Mol Sci. 2018 Aug 10;19(8). pii: E2362. doi: 10.3390/ijms19082362. Review.

45.

A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study.

Wang L, Phan DK, Syn N, Xiang X, Song H, Thuya WL, Yang S, Wong AL, Kumar AP, Yong WP, Sethi G, Ho PC, Goh BC.

Pharmaceutics. 2018 Aug 8;10(3). pii: E123. doi: 10.3390/pharmaceutics10030123.

46.

Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression.

Puar YR, Shanmugam MK, Fan L, Arfuso F, Sethi G, Tergaonkar V.

Biomedicines. 2018 Jul 27;6(3). pii: E82. doi: 10.3390/biomedicines6030082. Review.

47.

Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition.

Ko JH, Nam D, Um JY, Jung SH, Sethi G, Ahn KS.

Molecules. 2018 Jul 2;23(7). pii: E1601. doi: 10.3390/molecules23071601.

48.

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance.

Monisha J, Roy NK, Padmavathi G, Banik K, Bordoloi D, Khwairakpam AD, Arfuso F, Chinnathambi A, Alahmadi TA, Alharbi SA, Sethi G, Kumar AP, Kunnumakkara AB.

Cancers (Basel). 2018 Jul 10;10(7). pii: E228. doi: 10.3390/cancers10070228.

49.

Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ1-42 synthesis by suppressing the activation of STAT3 and cathepsin S.

Cao L, Cao X, Zhou Y, Nagpure BV, Wu ZY, Hu LF, Yang Y, Sethi G, Moore PK, Bian JS.

Brain Behav Immun. 2018 Oct;73:603-614. doi: 10.1016/j.bbi.2018.07.005. Epub 2018 Jul 5.

PMID:
29981830
50.

Role of RNF20 in cancer development and progression - a comprehensive review.

Sethi G, Shanmugam MK, Arfuso F, Kumar AP.

Biosci Rep. 2018 Jul 12;38(4). pii: BSR20171287. doi: 10.1042/BSR20171287. Print 2018 Aug 31. Review.

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