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Zika virus E protein alters the properties of human fetal neural stem cells by modulating microRNA circuitry.

Bhagat R, Prajapati B, Narwal S, Agnihotri N, Adlakha YK, Sen J, Mani S, Seth P.

Cell Death Differ. 2018 Jul 26. doi: 10.1038/s41418-018-0163-y. [Epub ahead of print]


Studies directed toward the asialoglycoprotein receptor mediated delivery of 5-fluoro-2'-deoxyuridine for hepatocellular carcinoma.

Rico L, Østergaard ME, Bell M, Seth PP, Hanessian S.

Bioorg Med Chem Lett. 2018 Aug 15;28(15):2652-2654. doi: 10.1016/j.bmcl.2018.06.002. Epub 2018 Jun 1.


Oncolytic adenovirus, rAd.DCN , inhibits breast tumor growth and lung metastasis in an immune-competent orthotopic xenograft model.

Zhao H, Wang H, Kong F, Xu W, Wang T, Xiao F, Wang L, Huang D, Seth P, Yang Y, Wang H.

Hum Gene Ther. 2018 Jul 21. doi: 10.1089/hum.2018.055. [Epub ahead of print]


Decorin-Modified Umbilical Cord Mesenchymal Stem Cells (MSCs) Attenuate Radiation-Induced Lung Injuries via Regulating Inflammation, Fibrotic Factors, and Immune Responses.

Liu D, Kong F, Yuan Y, Seth P, Xu W, Wang H, Xiao F, Wang L, Zhang Q, Yang Y, Wang H.

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):945-956. doi: 10.1016/j.ijrobp.2018.04.007. Epub 2018 Apr 16.


Overdose deaths involving opioids, cocaine, and psychostimulants - United States, 2015-2016.

Seth P, Scholl L, Rudd RA, Bacon S.

Am J Transplant. 2018 Jun;18(6):1556-1568. doi: 10.1111/ajt.14905. No abstract available.


Overdose Deaths Involving Opioids, Cocaine, and Psychostimulants - United States, 2015-2016.

Seth P, Scholl L, Rudd RA, Bacon S.

MMWR Morb Mortal Wkly Rep. 2018 Mar 30;67(12):349-358. doi: 10.15585/mmwr.mm6712a1.


Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor.

Gaus H, Miller CM, Seth PP, Harris EN.

Biochemistry. 2018 Apr 10;57(14):2061-2064. doi: 10.1021/acs.biochem.8b00126. Epub 2018 Mar 30.


Vital Signs: Trends in Emergency Department Visits for Suspected Opioid Overdoses - United States, July 2016-September 2017.

Vivolo-Kantor AM, Seth P, Gladden RM, Mattson CL, Baldwin GT, Kite-Powell A, Coletta MA.

MMWR Morb Mortal Wkly Rep. 2018 Mar 9;67(9):279-285. doi: 10.15585/mmwr.mm6709e1.


Quantifying the Epidemic of Prescription Opioid Overdose Deaths.

Seth P, Rudd RA, Noonan RK, Haegerich TM.

Am J Public Health. 2018 Apr;108(4):500-502. doi: 10.2105/AJPH.2017.304265. No abstract available.


Biomarkers for detection, prognosis and therapeutic assessment of neurological disorders.

Singh S, Gupta SK, Seth PK.

Rev Neurosci. 2018 Feb 21. pii: /j/revneuro.ahead-of-print/revneuro-2017-0097/revneuro-2017-0097.xml. doi: 10.1515/revneuro-2017-0097. [Epub ahead of print]


Previously Diagnosed HIV-Positive Persons: The Role of Centers for Disease Control and Prevention-Funded HIV Testing Programs in Addressing Their Needs.

Seth P, Wang G, Belcher L.

Sex Transm Dis. 2018 Jun;45(6):377-381. doi: 10.1097/OLQ.0000000000000766.


Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation.

Miller CM, Wan WB, Seth PP, Harris EN.

Nucleic Acid Ther. 2018 Apr;28(2):86-96. doi: 10.1089/nat.2017.0694. Epub 2018 Feb 13.


Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.

Miller CM, Tanowitz M, Donner AJ, Prakash TP, Swayze EE, Harris EN, Seth PP.

Nucleic Acid Ther. 2018 Jun;28(3):119-127. doi: 10.1089/nat.2017.0709. Epub 2018 Feb 9.


Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes.

Tanowitz M, Hettrick L, Revenko A, Kinberger GA, Prakash TP, Seth PP.

Nucleic Acids Res. 2017 Dec 1;45(21):12388-12400. doi: 10.1093/nar/gkx960.


Towards a First-Principles Determination of Effective Coulomb Interactions in Correlated Electron Materials: Role of Intershell Interactions.

Seth P, Hansmann P, van Roekeghem A, Vaugier L, Biermann S.

Phys Rev Lett. 2017 Aug 4;119(5):056401. doi: 10.1103/PhysRevLett.119.056401. Epub 2017 Aug 4.


Trends in Deaths Involving Heroin and Synthetic Opioids Excluding Methadone, and Law Enforcement Drug Product Reports, by Census Region - United States, 2006-2015.

O'Donnell JK, Gladden RM, Seth P.

MMWR Morb Mortal Wkly Rep. 2017 Sep 1;66(34):897-903. doi: 10.15585/mmwr.mm6634a2.


miR-217-casein kinase-2 cross talk regulates ERK activation in ganglioglioma.

Majumdar A, Ahmad F, Sheikh T, Bhagat R, Pathak P, Joshi SD, Seth P, Tandon V, Tripathi M, Saratchandra P, Sarkar C, Sen E.

J Mol Med (Berl). 2017 Nov;95(11):1215-1226. doi: 10.1007/s00109-017-1571-z. Epub 2017 Aug 25.


Estimation of the Percentage of Newly Diagnosed HIV-Positive Persons Linked to HIV Medical Care in CDC-Funded HIV Testing Programs.

Wang G, Pan Y, Seth P, Song R, Belcher L.

Eval Health Prof. 2017 Jan 1:163278717725372. doi: 10.1177/0163278717725372. [Epub ahead of print]


Lactate dehydrogenase activity drives hair follicle stem cell activation.

Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, Christofk HR, Lowry WE.

Nat Cell Biol. 2017 Sep;19(9):1017-1026. doi: 10.1038/ncb3575. Epub 2017 Aug 14.


Roles of quorum sensing molecules from Rhizobium etli RT1 in bacterial motility and biofilm formation.

Dixit S, Dubey RC, Maheshwari DK, Seth PK, Bajpai VK.

Braz J Microbiol. 2017 Oct - Dec;48(4):815-821. doi: 10.1016/j.bjm.2016.08.005. Epub 2017 Jul 8.


Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway.

Ren JG, Seth P, Ye H, Guo K, Hanai JI, Husain Z, Sukhatme VP.

Sci Rep. 2017 Jul 3;7(1):4537. doi: 10.1038/s41598-017-04626-4.


Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.

Østergaard ME, Nichols J, Dwight TA, Lima W, Jung ME, Swayze EE, Seth PP.

Mol Ther Nucleic Acids. 2017 Jun 16;7:20-30. doi: 10.1016/j.omtn.2017.02.001. Epub 2017 Feb 9.


Intra-generational protein malnutrition impairs temporal astrogenesis in rat brain.

Naik AA, Patro N, Seth P, Patro IK.

Biol Open. 2017 Jul 15;6(7):931-942. doi: 10.1242/bio.023432.


An Oncolytic Adenovirus Encoding Decorin and Granulocyte Macrophage Colony Stimulating Factor Inhibits Tumor Growth in a Colorectal Tumor Model by Targeting Pro-Tumorigenic Signals and via Immune Activation.

Liu Z, Yang Y, Zhang X, Wang H, Xu W, Wang H, Xiao F, Bai Z, Yao H, Ma X, Jin L, Wu C, Seth P, Zhang Z, Wang L.

Hum Gene Ther. 2017 Aug;28(8):667-680. doi: 10.1089/hum.2017.033.


Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity.

Prakash TP, Lima WF, Murray HM, Li W, Kinberger GA, Chappell AE, Gaus H, Seth PP, Bhat B, Crooke ST, Swayze EE.

Nucleic Acids Res. 2017 Jun 20;45(11):6994. doi: 10.1093/nar/gkx381. No abstract available.


Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver.

Donner AJ, Wancewicz EV, Murray HM, Greenlee S, Post N, Bell M, Lima WF, Swayze EE, Seth PP.

Nucleic Acid Ther. 2017 Aug;27(4):209-220. doi: 10.1089/nat.2017.0662. Epub 2017 Apr 27.


Deletion of Lactate Dehydrogenase-A in Myeloid Cells Triggers Antitumor Immunity.

Seth P, Csizmadia E, Hedblom A, Vuerich M, Xie H, Li M, Longhi MS, Wegiel B.

Cancer Res. 2017 Jul 1;77(13):3632-3643. doi: 10.1158/0008-5472.CAN-16-2938. Epub 2017 Apr 26.


Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses.

Patsoukis N, Weaver JD, Strauss L, Herbel C, Seth P, Boussiotis VA.

Front Immunol. 2017 Apr 11;8:330. doi: 10.3389/fimmu.2017.00330. eCollection 2017. Review.


SUMO-Specific Cysteine Protease 1 Promotes Epithelial Mesenchymal Transition of Prostate Cancer Cells via Regulating SMAD4 deSUMOylation.

Zhang X, Wang H, Wang H, Xiao F, Seth P, Xu W, Jia Q, Wu C, Yang Y, Wang L.

Int J Mol Sci. 2017 Apr 12;18(4). pii: E808. doi: 10.3390/ijms18040808.


Reactive Oxygen Species Synergize To Potently and Selectively Induce Cancer Cell Death.

Lee HY, Parkinson EI, Granchi C, Paterni I, Panigrahy D, Seth P, Minutolo F, Hergenrother PJ.

ACS Chem Biol. 2017 May 19;12(5):1416-1424. doi: 10.1021/acschembio.7b00015. Epub 2017 Apr 7.


Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

Posey KL, Coustry F, Veerisetty AC, Hossain M, Gattis D, Booten S, Alcorn JL, Seth PP, Hecht JT.

Mol Ther. 2017 Mar 1;25(3):705-714. doi: 10.1016/j.ymthe.2016.12.024. Epub 2017 Feb 3.


Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor.

Schmidt K, Prakash TP, Donner AJ, Kinberger GA, Gaus HJ, Low A, Østergaard ME, Bell M, Swayze EE, Seth PP.

Nucleic Acids Res. 2017 Mar 17;45(5):2294-2306. doi: 10.1093/nar/gkx060.


A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.

Southwell AL, Skotte NH, Villanueva EB, Østergaard ME, Gu X, Kordasiewicz HB, Kay C, Cheung D, Xie Y, Waltl S, Dal Cengio L, Findlay-Black H, Doty CN, Petoukhov E, Iworima D, Slama R, Ooi J, Pouladi MA, Yang XW, Swayze EE, Seth PP, Hayden MR.

Hum Mol Genet. 2017 Mar 15;26(6):1115-1132. doi: 10.1093/hmg/ddx021.


Japanese encephalitis virus induces human neural stem/progenitor cell death by elevating GRP78, PHB and hnRNPC through ER stress.

Mukherjee S, Singh N, Sengupta N, Fatima M, Seth P, Mahadevan A, Shankar SK, Bhattacharyya A, Basu A.

Cell Death Dis. 2017 Jan 19;8(1):e2556. doi: 10.1038/cddis.2016.394.


Increases in Drug and Opioid-Involved Overdose Deaths - United States, 2010-2015.

Rudd RA, Seth P, David F, Scholl L.

MMWR Morb Mortal Wkly Rep. 2016 Dec 30;65(5051):1445-1452. doi: 10.15585/mmwr.mm655051e1.


Email Between Patient and Provider: Assessing the Attitudes and Perspectives of 624 Primary Health Care Patients.

Seth P, Abu-Abed MI, Kapoor V, Nicholson K, Agarwal G.

JMIR Med Inform. 2016 Dec 22;4(4):e42. doi: 10.2196/medinform.5853.


CDC-funded HIV testing, HIV positivity, and linkage to HIV medical care in non-health care settings among young men who have sex with men (YMSM) in the United States.

Seth P, Walker T, Figueroa A.

AIDS Care. 2017 Jul;29(7):823-827. doi: 10.1080/09540121.2016.1271104. Epub 2016 Dec 21.


The expanding horizon of MicroRNAs in cellular reprogramming.

Adlakha YK, Seth P.

Prog Neurobiol. 2017 Jan;148:21-39. doi: 10.1016/j.pneurobio.2016.11.003. Epub 2016 Dec 12. Review.


Editorial (Thematic Issue: NeuroAIDS: Past, Present and Future).

Seth P.

Curr HIV Res. 2016;14(5):372. No abstract available.


Novel insights into role of miR-320a-VDAC1 axis in astrocyte-mediated neuronal damage in neuroAIDS.

Fatima M, Prajapati B, Saleem K, Kumari R, Mohindar Singh Singal C, Seth P.

Glia. 2017 Feb;65(2):250-263. doi: 10.1002/glia.23089. Epub 2016 Oct 20.


HIV Testing and Outcomes Among Hispanics/Latinos - United States, Puerto Rico, and U.S. Virgin Islands, 2014.

Rao S, Seth P, Walker T, Wang G, Mulatu MS, Gilford J, German EJ.

MMWR Morb Mortal Wkly Rep. 2016 Oct 14;65(40):1099-1103. doi: 10.15585/mmwr.mm6540a2.


Fentanyl Law Enforcement Submissions and Increases in Synthetic Opioid-Involved Overdose Deaths - 27 States, 2013-2014.

Gladden RM, Martinez P, Seth P.

MMWR Morb Mortal Wkly Rep. 2016 Aug 26;65(33):837-43. doi: 10.15585/mmwr.mm6533a2.


Clinical significance of T cell metabolic reprogramming in cancer.

Herbel C, Patsoukis N, Bardhan K, Seth P, Weaver JD, Boussiotis VA.

Clin Transl Med. 2016 Dec;5(1):29. doi: 10.1186/s40169-016-0110-9. Epub 2016 Aug 10. Review.


Disposition and Pharmacokinetics of a GalNAc3-Conjugated Antisense Oligonucleotide Targeting Human Lipoprotein (a) in Monkeys.

Yu RZ, Gunawan R, Post N, Zanardi T, Hall S, Burkey J, Kim TW, Graham MJ, Prakash TP, Seth PP, Swayze EE, Geary RS, Henry SP, Wang Y.

Nucleic Acid Ther. 2016 Dec;26(6):372-380. Epub 2016 Aug 8.


Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate.

Satake N, Duong C, Yoshida S, Oestergaard M, Chen C, Peralta R, Guo S, Seth PP, Li Y, Beckett L, Chung J, Nolta J, Nitin N, Tuscano JM.

Mol Med. 2016 Jul 22;22. doi: 10.2119/molmed.2015.00210. [Epub ahead of print]


The Medicinal Chemistry of Therapeutic Oligonucleotides.

Wan WB, Seth PP.

J Med Chem. 2016 Nov 10;59(21):9645-9667. Epub 2016 Jul 29. Review.


Risk Profiles of Women Experiencing Initial and Repeat Incarcerations: Implications for Prevention Programs.

Herbst JH, Branscomb-Burgess O, Gelaude DJ, Seth P, Parker S, Fogel CI.

AIDS Educ Prev. 2016 Aug;28(4):299-311. doi: 10.1521/aeap.2016.28.4.299.


Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion.

Juvekar A, Hu H, Yadegarynia S, Lyssiotis CA, Ullas S, Lien EC, Bellinger G, Son J, Hok RC, Seth P, Daly MB, Kim B, Scully R, Asara JM, Cantley LC, Wulf GM.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4338-47. doi: 10.1073/pnas.1522223113. Epub 2016 Jul 8.

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