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Items: 1 to 50 of 106

1.

Real-time molecular optical micro-imaging of EGFR mutations using a fluorescent erlotinib based tracer.

Patout M, Guisier F, Brune X, Bohn P, Romieu A, Sarafan-Vasseur N, Sesboüé R, Renard PY, Thiberville L, Salaün M.

BMC Pulm Med. 2019 Jan 7;19(1):3. doi: 10.1186/s12890-018-0760-z.

2.

Clinical Relevance of Gene Copy Number Variation in Metastatic Clear Cell Renal Cell Carcinoma.

Nouhaud FX, Blanchard F, Sesboue R, Flaman JM, Sabourin JC, Pfister C, Di Fiore F.

Clin Genitourin Cancer. 2018 Aug;16(4):e795-e805. doi: 10.1016/j.clgc.2018.02.013. Epub 2018 Feb 23.

PMID:
29548613
3.

Copy number variations in DCC/18q and ERBB2/17q are associated with disease-free survival in microsatellite stable colon cancer.

Sefrioui D, Vermeulin T, Blanchard F, Chapusot C, Beaussire L, Armengol-Debeir L, Sesboué R, Gangloff A, Hebbar M, Copin MC, Houivet E, Schwarz L, Clatot F, Tuech JJ, Bénichou J, Martin L, Bouvier AM, Sabourin JC, Sarafan-Vasseur N, Frébourg T, Lepage C, Michel P, Di Fiore F.

Int J Cancer. 2017 Apr 1;140(7):1653-1661. doi: 10.1002/ijc.30584.

4.

Photodynamic therapy using methylene blue in lung adenocarcinoma xenograft and hamster cheek pouch induced squamous cell carcinoma.

Obstoy B, Salaun M, Bohn P, Veresezan L, Sesboué R, Thiberville L.

Photodiagnosis Photodyn Ther. 2016 Sep;15:109-14. doi: 10.1016/j.pdpdt.2016.03.003. Epub 2016 Mar 15.

5.

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.

Mlecnik B, Bindea G, Angell HK, Maby P, Angelova M, Tougeron D, Church SE, Lafontaine L, Fischer M, Fredriksen T, Sasso M, Bilocq AM, Kirilovsky A, Obenauf AC, Hamieh M, Berger A, Bruneval P, Tuech JJ, Sabourin JC, Le Pessot F, Mauillon J, Rafii A, Laurent-Puig P, Speicher MR, Trajanoski Z, Michel P, Sesboüe R, Frebourg T, Pagès F, Valge-Archer V, Latouche JB, Galon J.

Immunity. 2016 Mar 15;44(3):698-711. doi: 10.1016/j.immuni.2016.02.025.

6.

Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer.

Sefrioui D, Sarafan-Vasseur N, Beaussire L, Baretti M, Gangloff A, Blanchard F, Clatot F, Sabourin JC, Sesboüé R, Frebourg T, Michel P, Di Fiore F.

Dig Liver Dis. 2015 Oct;47(10):884-90. doi: 10.1016/j.dld.2015.05.023. Epub 2015 Jun 5.

PMID:
26160500
7.

Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.

Maby P, Tougeron D, Hamieh M, Mlecnik B, Kora H, Bindea G, Angell HK, Fredriksen T, Elie N, Fauquembergue E, Drouet A, Leprince J, Benichou J, Mauillon J, Le Pessot F, Sesboüé R, Tuech JJ, Sabourin JC, Michel P, Frébourg T, Galon J, Latouche JB.

Cancer Res. 2015 Sep 1;75(17):3446-55. doi: 10.1158/0008-5472.CAN-14-3051. Epub 2015 Jun 9.

8.

Safety and performance analysis of acriflavine and methylene blue for in vivo imaging of precancerous lesions using fibered confocal fluorescence microscopy (FCFM): an experimental study.

Obstoy B, Salaun M, Veresezan L, Sesboüé R, Bohn P, Boland FX, Thiberville L.

BMC Pulm Med. 2015 Mar 31;15:30. doi: 10.1186/s12890-015-0020-4.

9.

The MDM2 285G-309G haplotype is associated with an earlier age of tumour onset in patients with Li-Fraumeni syndrome.

Renaux-Petel M, Sesboüé R, Baert-Desurmont S, Vasseur S, Fourneaux S, Bessenay E, Frébourg T, Bougeard G.

Fam Cancer. 2014 Mar;13(1):127-30. doi: 10.1007/s10689-013-9667-2.

PMID:
23884452
10.

A multiplex technology platform for the rapid analysis of clinically actionable genetic alterations and validation for BRAF p.V600E detection in 1549 cytologic and histologic specimens.

Smith DL, Lamy A, Beaudenon-Huibregtse S, Sesboüé R, Laosinchai-Wolf W, Sabourin JC, Labourier E.

Arch Pathol Lab Med. 2014 Mar;138(3):371-8. doi: 10.5858/arpa.2013-0002-OA. Epub 2013 Jun 28.

PMID:
23808402
11.

Genetic variations of the A13/A14 repeat located within the EGFR 3' untranslated region have no oncogenic effect in patients with colorectal cancer.

Sarafan-Vasseur N, Sefrioui D, Tougeron D, Lamy A, Blanchard F, Le Pessot F, Di Fiore F, Michel P, Bézieau S, Latouche JB, Frebourg T, Sesboüé R.

BMC Cancer. 2013 Apr 8;13:183. doi: 10.1186/1471-2407-13-183.

12.

Drastic effect of germline TP53 missense mutations in Li-Fraumeni patients.

Zerdoumi Y, Aury-Landas J, Bonaïti-Pellié C, Derambure C, Sesboüé R, Renaux-Petel M, Frebourg T, Bougeard G, Flaman JM.

Hum Mutat. 2013 Mar;34(3):453-61. doi: 10.1002/humu.22254. Epub 2013 Feb 11.

PMID:
23172776
13.

EGFR alterations and response to anti-EGFR therapy: is it a matter of gene amplification or gene copy number gain?

Sesboüé R, Le Pessot F, Di Fiore F, Frebourg T.

Br J Cancer. 2012 Jan 17;106(2):426-7; author reply 428. doi: 10.1038/bjc.2011.570. Epub 2011 Dec 20. No abstract available.

14.

Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls.

Lamy A, Blanchard F, Le Pessot F, Sesboüé R, Di Fiore F, Bossut J, Fiant E, Frébourg T, Sabourin JC.

Mod Pathol. 2011 Aug;24(8):1090-100. doi: 10.1038/modpathol.2011.60. Epub 2011 Apr 22.

15.

Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer.

Di Fiore F, Sesboüé R, Michel P, Sabourin JC, Frebourg T.

Br J Cancer. 2010 Dec 7;103(12):1765-72. doi: 10.1038/sj.bjc.6606008. Epub 2010 Nov 23. Review.

16.

HLA-A*0201-restricted CEA-derived peptide CAP1 is not a suitable target for T-cell-based immunotherapy.

Fauquembergue E, Toutirais O, Tougeron D, Drouet A, Le Gallo M, Desille M, Cabillic F, de La Pintière CT, Iero M, Rivoltini L, Baert-Desurmont S, Leprince J, Vaudry H, Sesboué R, Frébourg T, Latouche JB, Catros V.

J Immunother. 2010 May;33(4):402-13. doi: 10.1097/CJI.0b013e3181d366da.

PMID:
20386466
17.

Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.

Tougeron D, Fauquembergue E, Rouquette A, Le Pessot F, Sesboüé R, Laurent M, Berthet P, Mauillon J, Di Fiore F, Sabourin JC, Michel P, Tosi M, Frébourg T, Latouche JB.

Mod Pathol. 2009 Sep;22(9):1186-95. doi: 10.1038/modpathol.2009.80. Epub 2009 Jun 5.

18.

Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy.

Bohers E, Sarafan-Vasseur N, Drouet A, Paresy M, Latouche JB, Flaman JM, Sesboüé R, Frebourg T.

Hum Genet. 2008 Dec;124(5):473-8. doi: 10.1007/s00439-008-0572-y. Epub 2008 Oct 19.

PMID:
18932004
19.

Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families.

Bougeard G, Sesboüé R, Baert-Desurmont S, Vasseur S, Martin C, Tinat J, Brugières L, Chompret A, de Paillerets BB, Stoppa-Lyonnet D, Bonaïti-Pellié C, Frébourg T; French LFS working group.

J Med Genet. 2008 Aug;45(8):535-8. doi: 10.1136/jmg.2008.057570. Epub 2008 May 29.

PMID:
18511570
20.

Molecular predictive factors for progression of high-grade preinvasive bronchial lesions.

Salaün M, Sesboüé R, Moreno-Swirc S, Metayer J, Bota S, Bourguignon J, Thiberville L.

Am J Respir Crit Care Med. 2008 Apr 15;177(8):880-6. Epub 2007 Oct 25.

PMID:
17962638
21.

Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy.

Di Fiore F, Blanchard F, Charbonnier F, Le Pessot F, Lamy A, Galais MP, Bastit L, Killian A, Sesboüé R, Tuech JJ, Queuniet AM, Paillot B, Sabourin JC, Michot F, Michel P, Frebourg T.

Br J Cancer. 2007 Apr 23;96(8):1166-9. Epub 2007 Mar 20.

22.

A simple method for the routine detection of somatic quantitative genetic alterations in colorectal cancer.

Killian A, Di Fiore F, Le Pessot F, Blanchard F, Lamy A, Raux G, Flaman JM, Paillot B, Michel P, Sabourin JC, Tuech JJ, Michot F, Kerckaert JP, Sesboüé R, Frebourg T.

Gastroenterology. 2007 Feb;132(2):645-53. Epub 2006 Dec 3.

PMID:
17258723
23.

Hyaluronectin modulation of lung metastasis in nude mice.

Paris S, Sesboüé R, Chauzy C, Maingonnat C, Delpech B.

Eur J Cancer. 2006 Dec;42(18):3253-9. Epub 2006 Aug 23.

PMID:
16930992
24.

Contribution of the BOP1 gene, located on 8q24, to colorectal tumorigenesis.

Killian A, Sarafan-Vasseur N, Sesboüé R, Le Pessot F, Blanchard F, Lamy A, Laurent M, Flaman JM, Frébourg T.

Genes Chromosomes Cancer. 2006 Sep;45(9):874-81.

PMID:
16804918
25.

Inactivation of the RRB1-Pescadillo pathway involved in ribosome biogenesis induces chromosomal instability.

Killian A, Le Meur N, Sesboüé R, Bourguignon J, Bougeard G, Gautherot J, Bastard C, Frébourg T, Flaman JM.

Oncogene. 2004 Nov 11;23(53):8597-602.

PMID:
15467761
26.

Metastasis models: the green fluorescent revolution?

Paris S, Sesboüé R.

Carcinogenesis. 2004 Dec;25(12):2285-92. Epub 2004 Jun 24. Review.

PMID:
15217904
27.

Hyaluronidase in sera of tumour-bearing nude mice.

Maingonnat C, Courel MN, Bertrand P, Vincent JC, Sesboüé R, Delpech B.

Biomarkers. 2003 May-Aug;8(3-4):333-8.

PMID:
12944181
28.

Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer.

Lamy A, Sesboüé R, Bourguignon J, Dautréaux B, Métayer J, Frébourg T, Thiberville L.

Int J Cancer. 2002 Jul 10;100(2):189-93.

29.

Hyaluronan digestion and synthesis in an experimental model of metastatic tumour.

Delpech B, Courel MN, Maingonnat C, Chauzy C, Sesboüé R, Pratesi G.

Histochem J. 2001 Sep-Oct;33(9-10):553-8.

PMID:
12005027
30.

Overexpression of B-type cyclins alters chromosomal segregation.

Sarafan-Vasseur N, Lamy A, Bourguignon J, Le Pessot F, Hieter P, Sesboüé R, Bastard C, Frébourg T, Flaman JM.

Oncogene. 2002 Mar 27;21(13):2051-7.

31.

Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains.

Paris S, Sesboüé R, Delpech B, Chauzy C, Thiberville L, Martin JP, Frébourg T, Diarra-Mehrpour M.

Int J Cancer. 2002 Feb 10;97(5):615-20.

32.

Follow-up of bronchial precancerous lesions and carcinoma in situ using fluorescence endoscopy.

Bota S, Auliac JB, Paris C, Métayer J, Sesboüé R, Nouvet G, Thiberville L.

Am J Respir Crit Care Med. 2001 Nov 1;164(9):1688-93.

PMID:
11719311
33.

Analysis of anti-neutrophil cytoplasmic antibodies (ANCA): frequency and specificity in a sample of 191 homozygous (PiZZ) alpha1-antitrypsin-deficient subjects.

Audrain MA, Sesboüé R, Baranger TA, Elliott J, Testa A, Martin JP, Lockwood CM, Esnault VL.

Nephrol Dial Transplant. 2001 Jan;16(1):39-44.

PMID:
11208991
34.

Re: Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.

Lamy A, Métayer J, Thiberville L, Frébourg T, Sesboüé R.

J Natl Cancer Inst. 2001 Jan 3;93(1):66-8. No abstract available.

PMID:
11136849
35.

[Proteins of the inter-alpha trypsin inhibitor (ITI) family. A major role in the biology of the extracellular matrix].

Cuvelier A, Muir JF, Martin JP, Sesboüé R.

Rev Mal Respir. 2000 Apr;17(2):437-46. Review. French.

PMID:
10859762
36.

Predictive survival markers in patients with surgically resected non-small cell lung carcinoma.

Moldvay J, Scheid P, Wild P, Nabil K, Siat J, Borrelly J, Marie B, Farré G, Labib T, Pottier G, Sesboüé R, Bronner C, Vignaud JM, Martinet Y, Martinet N.

Clin Cancer Res. 2000 Mar;6(3):1125-34.

37.

Distribution of alpha(1)-antitrypsin alleles in patients with bronchiectasis.

Cuvelier A, Muir JF, Hellot MF, Benhamou D, Martin JP, Bénichou J, Sesboüé R.

Chest. 2000 Feb;117(2):415-9.

PMID:
10669684
38.

Immunohistochemical distribution of inter-alpha-trypsin inhibitor chains in normal and malignant human lung tissue.

Bourguignon J, Borghi H, Sesboüé R, Diarra-Mehrpour M, Bernaudin JF, Métayer J, Martin JP, Thiberville L.

J Histochem Cytochem. 1999 Dec;47(12):1625-32.

PMID:
10567446
39.

Alpha1-antitrypsin phenotypes and anti-neutrophil cytoplasmic auto-antibodies in inflammatory bowel disease.

Taddei C, Audrain MA, Reumaux D, Sesboüe R, Testa A, Galmiche JP, Duthilleul P, Colombel JF, Esnault VL.

Eur J Gastroenterol Hepatol. 1999 Nov;11(11):1293-8.

PMID:
10563543
40.

Polymerase chain reaction detection of S and Z alpha-1-antitrypsin variants by duplex PCR assay.

Lucotte G, Sesboüé R.

Mol Cell Probes. 1999 Oct;13(5):389-91.

PMID:
10508561
41.

Assembly and secretion of recombinant chains of human inter-alpha-trypsin inhibitor in COS-7 cells.

Martin-Vandelet N, Paris S, Bourguignon J, Sesboüé R, Martin JP, Diarra-Mehrpour M.

Eur J Biochem. 1999 Jan;259(1-2):476-84.

42.

Transverse formamide gradients as a simple and easy way to optimise DNA single-strand conformation polymorphism analysis.

Paccoud B, Bourguignon J, Diarra-Mehrpour M, Martin JP, Sesboüé R.

Nucleic Acids Res. 1998 May 1;26(9):2245-6.

43.

Human pre-alpha-inhibitor: isolation from a by-product of industrial scale plasma fractionation and structural analysis of its H3 heavy chain.

Mizon C, Héron A, Capon C, Sautiere P, Michalski C, Sesboüé R, Mizon J.

J Chromatogr B Biomed Sci Appl. 1997 May 9;692(2):281-91.

PMID:
9188816
44.

Purification and characterization of pig inter-alpha-inhibitor and its constitutive heavy chains.

Carrette O, Mizon C, Sautière P, Sesboüé R, Mizon J.

Biochim Biophys Acta. 1997 Mar 7;1338(1):21-30.

PMID:
9074612
45.

Absence of the alpha-1-antitrypsin PI*Z allele in Tunisia substantiates the particular genetic structure of African populations.

Makni S, Zitouni M, Ayed K, Mhirii S, Azabi S, Cherif F, Maalej M, Martin JP, Sesboüé R.

Am J Hum Biol. 1997;9(2):223-224. doi: 10.1002/(SICI)1520-6300(1997)9:2<223::AID-AJHB8>3.0.CO;2-0.

PMID:
28561523
46.
47.

[Metalloproteinases in the extracellular matrix: structure and activity].

Cuvelier A, Kuntz C, Sesboüé R, Muir JF, Martin JP.

Rev Mal Respir. 1997 Jan;14(1):1-10. Review. French.

PMID:
9082500
48.

Substitution of carbonate by acetate buffer for IgG coating in sandwich ELISA.

Cuvelier A, Bourguignon J, Muir JF, Martin JP, Sesboüé R.

J Immunoassay. 1996 Nov;17(4):371-82.

PMID:
8957766
49.

Relationship between a mild alpha 1 proteinase inhibitor deficiency and respiratory symptoms in a family.

Huet-Duvillier G, Balduyck M, Watrigant Y, Sesboue R, Thiebaut C, Lafitte JJ, Degand P.

Ann Clin Biochem. 1995 Nov;32 ( Pt 6):545-9.

PMID:
8579286
50.

Involvement of the three inter-alpha-trypsin inhibitor (ITI) heavy chains in each member of the serum ITI family.

Héron A, Bourguignon J, Diarra-Mehrpour M, Dautréaux B, Martin JP, Sesboüé R.

FEBS Lett. 1995 Oct 30;374(2):195-8.

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