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Items: 36


Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes.

Dirice E, Kahraman S, De Jesus DF, El Ouaamari A, Basile G, Baker RL, Yigit B, Piehowski PD, Kim MJ, Dwyer AJ, Ng RWS, Schuster C, Vethe H, Martinov T, Ishikawa Y, Teo AKK, Smith RD, Hu J, Haskins K, Serwold T, Qian WJ, Fife BT, Kissler S, Kulkarni RN.

Nat Metab. 2019 May;1(5):509-518. doi: 10.1038/s42255-019-0061-8. Epub 2019 May 6.


Isolation of Highly Viable Thymic Epithelial Cells for Use in In Vitro and In Vivo Experiments.

Kim MJ, Serwold T.

Methods Mol Biol. 2019;1899:143-156. doi: 10.1007/978-1-4939-8938-6_11.


Interleukin-17-Producing γδ T Cells Originate from SOX13+ Progenitors that Are Independent of γδTCR Signaling.

Spidale NA, Sylvia K, Narayan K, Miu B, Frascoli M, Melichar HJ, Zhihao W, Kisielow J, Palin A, Serwold T, Love P, Kobayashi M, Yoshimoto M, Jain N, Kang J.

Immunity. 2018 Nov 20;49(5):857-872.e5. doi: 10.1016/j.immuni.2018.09.010. Epub 2018 Nov 6.


The CD11a and Endothelial Protein C Receptor Marker Combination Simplifies and Improves the Purification of Mouse Hematopoietic Stem Cells.

Karimzadeh A, Scarfone VM, Varady E, Chao C, Grathwohl K, Fathman JW, Fruman DA, Serwold T, Inlay MA.

Stem Cells Transl Med. 2018 Jun;7(6):468-476. doi: 10.1002/sctm.17-0189. Epub 2018 Mar 15.


In Vivo Enrichment of Diabetogenic T Cells.

Thelin MA, Kissler S, Vigneault F, Watters AL, White D, Koshy ST, Vermillion SA, Mooney DJ, Serwold T, Ali OA.

Diabetes. 2017 Aug;66(8):2220-2229. doi: 10.2337/db16-0946. Epub 2017 Apr 10.


The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection.

Schuster C, Gerold KD, Schober K, Probst L, Boerner K, Kim MJ, Ruckdeschel A, Serwold T, Kissler S.

Immunity. 2015 May 19;42(5):942-52. doi: 10.1016/j.immuni.2015.04.011. Epub 2015 May 12.


CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1.

Vazquez SE, Inlay MA, Serwold T.

Exp Hematol. 2015 Jul;43(7):578-85. doi: 10.1016/j.exphem.2015.04.001. Epub 2015 Apr 16.


Young, proliferative thymic epithelial cells engraft and function in aging thymuses.

Kim MJ, Miller CM, Shadrach JL, Wagers AJ, Serwold T.

J Immunol. 2015 May 15;194(10):4784-95. doi: 10.4049/jimmunol.1403158. Epub 2015 Apr 13.


High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice.

Rao TN, Marks-Bluth J, Sullivan J, Gupta MK, Chandrakanthan V, Fitch SR, Ottersbach K, Jang YC, Piao X, Kulkarni RN, Serwold T, Pimanda JE, Wagers AJ.

Stem Cell Res. 2015 May;14(3):307-22. doi: 10.1016/j.scr.2015.02.001. Epub 2015 Feb 18.


Expression of TCR-Vβ peptides by murine bone marrow cells does not identify T-cell progenitors.

Abbey JL, Karsunky H, Serwold T, Papathanasiou P, Weissman IL, O'Neill HC.

J Cell Mol Med. 2015 Aug;19(8):1956-64. doi: 10.1111/jcmm.12572. Epub 2015 Mar 6.


Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.

Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ.

Science. 2014 May 9;344(6184):649-52. doi: 10.1126/science.1251152. Epub 2014 May 5.


Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development.

Inlay MA, Serwold T, Mosley A, Fathman JW, Dimov IK, Seita J, Weissman IL.

Stem Cell Reports. 2014 Mar 20;2(4):457-72. doi: 10.1016/j.stemcr.2014.02.001. eCollection 2014 Apr 8.


Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression.

Garfin PM, Min D, Bryson JL, Serwold T, Edris B, Blackburn CC, Richie ER, Weinberg KI, Manley NR, Sage J, Viatour P.

J Exp Med. 2013 Jun 3;210(6):1087-97. doi: 10.1084/jem.20121716. Epub 2013 May 13.


Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy.

Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT.

Cell. 2013 May 9;153(4):828-39. doi: 10.1016/j.cell.2013.04.015.


Gene Expression Commons: an open platform for absolute gene expression profiling.

Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL.

PLoS One. 2012;7(7):e40321. doi: 10.1371/journal.pone.0040321. Epub 2012 Jul 18.


In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors.

Richie Ehrlich LI, Serwold T, Weissman IL.

Blood. 2011 Mar 3;117(9):2618-24. doi: 10.1182/blood-2010-05-287102. Epub 2010 Dec 16.


T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.

Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18939-43. doi: 10.1073/pnas.1013230107. Epub 2010 Oct 18.


Comprehensive methylome map of lineage commitment from haematopoietic progenitors.

Ji H, Ehrlich LI, Seita J, Murakami P, Doi A, Lindau P, Lee H, Aryee MJ, Irizarry RA, Kim K, Rossi DJ, Inlay MA, Serwold T, Karsunky H, Ho L, Daley GQ, Weissman IL, Feinberg AP.

Nature. 2010 Sep 16;467(7313):338-42. doi: 10.1038/nature09367. Epub 2010 Aug 15.


Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.

Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH.

J Immunol. 2010 Sep 15;185(6):3564-73. doi: 10.4049/jimmunol.0903098. Epub 2010 Aug 13.


Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.

Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL.

Genes Dev. 2009 Oct 15;23(20):2376-81. doi: 10.1101/gad.1836009. Erratum in: Genes Dev. 2013 Sep 15;27(18):2063.


Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis.

Serwold T, Ehrlich LI, Weissman IL.

Blood. 2009 Jan 22;113(4):807-15. doi: 10.1182/blood-2008-08-173682. Epub 2008 Oct 16.


Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages.

Karsunky H, Inlay MA, Serwold T, Bhattacharya D, Weissman IL.

Blood. 2008 Jun 15;111(12):5562-70. doi: 10.1182/blood-2007-11-126219. Epub 2008 Apr 18.


Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes.

Serwold T, Hochedlinger K, Inlay MA, Jaenisch R, Weissman IL.

J Immunol. 2007 Jul 15;179(2):928-38.


New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors.

Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E.

Cell. 2006 Jul 28;126(2):415-26.


All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway.

Shastri N, Cardinaud S, Schwab SR, Serwold T, Kunisawa J.

Immunol Rev. 2005 Oct;207:31-41. Review.


ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum.

Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N.

Nature. 2002 Oct 3;419(6906):480-3.


Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules.

Shastri N, Schwab S, Serwold T.

Annu Rev Immunol. 2002;20:463-93. Epub 2001 Oct 4.


ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

Serwold T, Gaw S, Shastri N.

Nat Immunol. 2001 Jul;2(7):644-51.


Reading within the lines: naturally processed peptides displayed by MHC class I molecules.

Shastri N, Serwold T, Paz P.

Curr Opin Immunol. 1998 Apr;10(2):137-44. Review.


Does nitric oxide regulate capacitative Ca influx in HEK 293 cells?

Bischof G, Serwold TF, Machen TE.

Cell Calcium. 1997 Feb;21(2):135-42.


Chimeric human calcitonin and glucagon receptors reveal two dissociable calcitonin interaction sites.

Stroop SD, Kuestner RE, Serwold TF, Chen L, Moore EE.

Biochemistry. 1995 Jan 24;34(3):1050-7.


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