Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 143

1.
2.

CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes.

Sandor AM, Lindsay RS, Dyjack N, Whitesell JC, Rios C, Bradley BJ, Haskins K, Serreze DV, Geurts AM, Chen YG, Seibold MA, Jacobelli J, Friedman RS.

Front Immunol. 2019 Jan 31;10:99. doi: 10.3389/fimmu.2019.00099. eCollection 2019.

3.

A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in NOD Mice.

Presa M, Racine JJ, Dwyer JR, Lamont DJ, Ratiu JJ, Sarsani VK, Chen YG, Geurts A, Schmitz I, Stearns T, Allocco J, Chapman HD, Serreze DV.

J Immunol. 2018 Oct 1;201(7):1907-1917. doi: 10.4049/jimmunol.1800465. Epub 2018 Aug 20.

PMID:
30127089
4.

HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.

Schloss J, Ali R, Racine JJ, Chapman HD, Serreze DV, DiLorenzo TP.

J Immunol. 2018 May 15;200(10):3353-3363. doi: 10.4049/jimmunol.1701652. Epub 2018 Apr 9.

5.

Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development.

Racine JJ, Stewart I, Ratiu J, Christianson G, Lowell E, Helm K, Allocco J, Maser RS, Chen YG, Lutz CM, Roopenian D, Schloss J, DiLorenzo TP, Serreze DV.

Diabetes. 2018 May;67(5):923-935. doi: 10.2337/db17-1467. Epub 2018 Feb 22.

6.

Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy.

Wang Q, Racine JJ, Ratiu JJ, Wang S, Ettinger R, Wasserfall C, Atkinson MA, Serreze DV.

J Immunol. 2017 Dec 1;199(11):3757-3770. doi: 10.4049/jimmunol.1700822. Epub 2017 Oct 20.

7.

Antibiotic-associated Manipulation of the Gut Microbiota and Phenotypic Restoration in NOD Mice.

Fahey JR, Lyons BL, Olekszak HL, Mourino AJ, Ratiu JJ, Racine JJ, Chapman HD, Serreze DV, Baker DL, Hendrix NK.

Comp Med. 2017 Aug 1;67(4):335-343.

8.

Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes.

Ratiu JJ, Racine JJ, Hasham MG, Wang Q, Branca JA, Chapman HD, Zhu J, Donghia N, Philip V, Schott WH, Wasserfall C, Atkinson MA, Mills KD, Leeth CM, Serreze DV.

J Immunol. 2017 Jun 1;198(11):4255-4267. doi: 10.4049/jimmunol.1700024. Epub 2017 May 1.

9.

Interferon-γ Limits Diabetogenic CD8+ T-Cell Effector Responses in Type 1 Diabetes.

Driver JP, Racine JJ, Ye C, Lamont DJ, Newby BN, Leeth CM, Chapman HD, Brusko TM, Chen YG, Mathews CE, Serreze DV.

Diabetes. 2017 Mar;66(3):710-721. doi: 10.2337/db16-0846. Epub 2016 Dec 5.

10.

Autoimmune manifestations in aged mice arise from early-life immune dysregulation.

Mahmoud TI, Wang J, Karnell JL, Wang Q, Wang S, Naiman B, Gross P, Brohawn PZ, Morehouse C, Aoyama J, Wasserfall C, Carter L, Atkinson MA, Serreze DV, Braley-Mullen H, Mustelin T, Kolbeck R, Herbst R, Ettinger R.

Sci Transl Med. 2016 Oct 19;8(361):361ra137.

11.

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.

Lin B, Ciecko AE, MacKinney E, Serreze DV, Chen YG.

Immunogenetics. 2017 Mar;69(3):193-198. doi: 10.1007/s00251-016-0957-3. Epub 2016 Oct 28.

12.

Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.

Serreze DV, Niens M, Kulik J, DiLorenzo TP.

Methods Mol Biol. 2016;1438:137-51. doi: 10.1007/978-1-4939-3661-8_9. Review.

PMID:
27150089
13.

B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice.

Leeth CM, Racine J, Chapman HD, Arpa B, Carrillo J, Carrascal J, Wang Q, Ratiu J, Egia-Mendikute L, Rosell-Mases E, Stratmann T, Verdaguer J, Serreze DV.

Diabetes. 2016 Jul;65(7):1977-1987. doi: 10.2337/db15-1606. Epub 2016 Mar 9.

14.

The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.

Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV.

J Immunol. 2015 Oct 1;195(7):3011-9. doi: 10.4049/jimmunol.1402446. Epub 2015 Aug 17.

15.

Sudden acquired retinal degeneration syndrome (SARDS) - a review and proposed strategies toward a better understanding of pathogenesis, early diagnosis, and therapy.

Komáromy AM, Abrams KL, Heckenlively JR, Lundy SK, Maggs DJ, Leeth CM, MohanKumar PS, Petersen-Jones SM, Serreze DV, van der Woerdt A.

Vet Ophthalmol. 2016 Jul;19(4):319-31. doi: 10.1111/vop.12291. Epub 2015 Jun 20. Review.

16.

Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice.

Simecek P, Churchill GA, Yang H, Rowe LB, Herberg L, Serreze DV, Leiter EH.

G3 (Bethesda). 2015 Mar 3;5(5):771-5. doi: 10.1534/g3.115.017046.

17.

A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells.

Tsaih SW, Presa M, Khaja S, Ciecko AE, Serreze DV, Chen YG.

Genes Immun. 2015 Apr-May;16(3):221-30. doi: 10.1038/gene.2014.81. Epub 2015 Feb 5.

18.

Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses.

Lamont D, Mukherjee G, Kumar PR, Samanta D, McPhee CG, Kay TW, Almo SC, DiLorenzo TP, Serreze DV.

J Immunol. 2014 Sep 1;193(5):2135-46. doi: 10.4049/jimmunol.1400997. Epub 2014 Jul 25.

19.

In vivo detection of peripherin-specific autoreactive B cells during type 1 diabetes pathogenesis.

Garabatos N, Alvarez R, Carrillo J, Carrascal J, Izquierdo C, Chapman HD, Presa M, Mora C, Serreze DV, Verdaguer J, Stratmann T.

J Immunol. 2014 Apr 1;192(7):3080-90. doi: 10.4049/jimmunol.1301053. Epub 2014 Mar 7.

20.

DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8⁺ T cells independently of PD-1 and PD-L1.

Mukherjee G, Geliebter A, Babad J, Santamaria P, Serreze DV, Freeman GJ, Tarbell KV, Sharpe A, DiLorenzo TP.

Int Immunol. 2013 Nov;25(11):651-60. doi: 10.1093/intimm/dxt031. Epub 2013 Sep 10.

21.

Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.

Unger WW, Pearson T, Abreu JR, Laban S, van der Slik AR, der Kracht SM, Kester MG, Serreze DV, Shultz LD, Griffioen M, Drijfhout JW, Greiner DL, Roep BO.

PLoS One. 2012;7(11):e49213. doi: 10.1371/journal.pone.0049213. Epub 2012 Nov 14.

22.

B7x in the periphery abrogates pancreas-specific damage mediated by self-reactive CD8 T cells.

Lee JS, Scandiuzzi L, Ray A, Wei J, Hofmeyer KA, Abadi YM, Loke P, Lin J, Yuan J, Serreze DV, Allison JP, Zang X.

J Immunol. 2012 Oct 15;189(8):4165-74. doi: 10.4049/jimmunol.1201241. Epub 2012 Sep 12.

23.

Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.

Stolp J, Chen YG, Cox SL, Henck V, Zhang W, Tsaih SW, Chapman H, Stearns T, Serreze DV, Silveira PA.

J Immunol. 2012 Aug 1;189(3):1406-17. doi: 10.4049/jimmunol.1200120. Epub 2012 Jun 25.

24.

A MusD retrotransposon insertion in the mouse Slc6a5 gene causes alterations in neuromuscular junction maturation and behavioral phenotypes.

Bogdanik LP, Chapman HD, Miers KE, Serreze DV, Burgess RW.

PLoS One. 2012;7(1):e30217. doi: 10.1371/journal.pone.0030217. Epub 2012 Jan 17.

25.

Calcium insufficiency accelerates type 1 diabetes in vitamin D receptor-deficient nonobese diabetic (NOD) mice.

Driver JP, Lamont DJ, Gysemans C, Mathieu C, Serreze DV.

Endocrinology. 2011 Dec;152(12):4620-9. doi: 10.1210/en.2011-1074. Epub 2011 Sep 27.

26.

Genetic control of murine invariant natural killer T-cell development dynamically differs dependent on the examined tissue type.

Chen YG, Tsaih SW, Serreze DV.

Genes Immun. 2012 Feb;13(2):164-74. doi: 10.1038/gene.2011.68. Epub 2011 Sep 22.

27.

Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies.

Serreze DV, Chapman HD, Niens M, Dunn R, Kehry MR, Driver JP, Haller M, Wasserfall C, Atkinson MA.

Diabetes. 2011 Nov;60(11):2914-21. doi: 10.2337/db11-0705. Epub 2011 Sep 16.

28.

Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice.

Chen YG, Scheuplein F, Driver JP, Hewes AA, Reifsnyder PC, Leiter EH, Serreze DV.

J Immunol. 2011 Apr 1;186(7):4278-84. doi: 10.4049/jimmunol.1003733. Epub 2011 Feb 25.

29.

Targeting of a T cell agonist peptide to lysosomes by DNA vaccination induces tolerance in the nonobese diabetic mouse.

Rivas EI, Driver JP, Garabatos N, Presa M, Mora C, Rodriguez F, Serreze DV, Stratmann T.

J Immunol. 2011 Apr 1;186(7):4078-87. doi: 10.4049/jimmunol.0902395. Epub 2011 Feb 23.

30.

Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach.

Niens M, Grier AE, Marron M, Kay TW, Greiner DL, Serreze DV.

Diabetes. 2011 Apr;60(4):1229-36. doi: 10.2337/db10-1523. Epub 2011 Feb 23.

31.

Unmasking genes in a type 1 diabetes-resistant mouse strain that enhances pathogenic CD8 T-cell responses.

Driver JP, Chen YG, Zhang W, Asrat S, Serreze DV.

Diabetes. 2011 Apr;60(4):1354-9. doi: 10.2337/db10-0885. Epub 2011 Feb 9.

32.

Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a β-cell neo-self-antigen in type 1 diabetes prone NOD mice.

Cox SL, Stolp J, Hallahan NL, Counotte J, Zhang W, Serreze DV, Basten A, Silveira PA.

Eur J Immunol. 2010 Dec;40(12):3413-25. doi: 10.1002/eji.201040817. Epub 2010 Nov 11.

33.

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease.

Driver JP, Serreze DV, Chen YG.

Semin Immunopathol. 2011 Jan;33(1):67-87. doi: 10.1007/s00281-010-0204-1. Epub 2010 Apr 28. Review.

PMID:
20424843
34.

Peripherin-reactive antibodies in mouse, rabbit, and human blood.

Strom A, Sonier B, Chapman HD, Mojibian M, Wang GS, Slatculescu CR, Serreze DV, Scott FW.

J Proteome Res. 2010 Mar 5;9(3):1203-8. doi: 10.1021/pr900492y.

35.

Bridging mice to men: using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans.

Serreze DV, Niens M, Kulik J, Dilorenzo TP.

Methods Mol Biol. 2010;602:119-34. doi: 10.1007/978-1-60761-058-8_8.

PMID:
20012396
36.

Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette.

Driver JP, Scheuplein F, Chen YG, Grier AE, Wilson SB, Serreze DV.

Diabetes. 2010 Feb;59(2):423-32. doi: 10.2337/db09-1116. Epub 2009 Nov 10.

37.

A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes.

Scheuplein F, Rissiek B, Driver JP, Chen YG, Koch-Nolte F, Serreze DV.

J Autoimmun. 2010 Mar;34(2):145-54. doi: 10.1016/j.jaut.2009.08.012. Epub 2009 Oct 1.

38.

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.

Wesolowski J, Alzogaray V, Reyelt J, Unger M, Juarez K, Urrutia M, Cauerhff A, Danquah W, Rissiek B, Scheuplein F, Schwarz N, Adriouch S, Boyer O, Seman M, Licea A, Serreze DV, Goldbaum FA, Haag F, Koch-Nolte F.

Med Microbiol Immunol. 2009 Aug;198(3):157-74. doi: 10.1007/s00430-009-0116-7. Epub 2009 Jun 16. Review.

39.

Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.

Mangada J, Pearson T, Brehm MA, Wicker LS, Peterson LB, Shultz LD, Serreze DV, Rossini AA, Greiner DL.

Diabetes. 2009 Jan;58(1):165-73. doi: 10.2337/db08-0275. Epub 2008 Nov 4.

40.

Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.

Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV.

Diabetes. 2008 Dec;57(12):3273-80. doi: 10.2337/db08-0767. Epub 2008 Sep 5.

41.

Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells.

Chaparro RJ, Burton AR, Serreze DV, Vignali DA, DiLorenzo TP.

J Immunol Methods. 2008 Jun 1;335(1-2):106-15. doi: 10.1016/j.jim.2008.03.007. Epub 2008 Apr 8.

42.

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6374-9. doi: 10.1073/pnas.0802644105. Epub 2008 Apr 22.

43.

Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.

Serreze DV, Choisy-Rossi CM, Grier AE, Holl TM, Chapman HD, Gahagan JR, Osborne MA, Zhang W, King BL, Brown A, Roopenian D, Marron MP.

J Immunol. 2008 Mar 1;180(5):3250-9.

44.
45.

Unexpected functional consequences of xenogeneic transgene expression in beta-cells of NOD mice.

Leiter EH, Reifsnyder P, Driver J, Kamdar S, Choisy-Rossi C, Serreze DV, Hara M, Chervonsky A.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:14-22.

PMID:
17919174
46.

In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.

Jarchum I, Baker JC, Yamada T, Takaki T, Marron MP, Serreze DV, DiLorenzo TP.

Diabetes. 2007 Oct;56(10):2551-60. Epub 2007 Jul 9.

47.

Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice.

Chen YG, Driver JP, Silveira PA, Serreze DV.

Immunogenetics. 2007 Sep;59(9):705-12. Epub 2007 Jul 10.

PMID:
17619875
48.

Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men.

Unger WW, Pinkse GG, Mulder-van der Kracht S, van der Slik AR, Kester MG, Ossendorp F, Drijfhout JW, Serreze DV, Roep BO.

Ann N Y Acad Sci. 2007 Apr;1103:192-5. Epub 2007 Mar 21.

PMID:
17376840
49.

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

Serreze DV, Marron MP, Dilorenzo TP.

Ann N Y Acad Sci. 2007 Apr;1103:103-11. Epub 2007 Mar 21.

PMID:
17376821
50.

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.

Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P.

Nat Genet. 2007 Mar;39(3):329-37. Epub 2007 Feb 4.

Supplemental Content

Loading ...
Support Center