Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 104

1.

Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Substrates (TAILS) N-Terminomics.

Zelanis A, Oliveira AK, Prudova A, Huesgen PF, Tashima AK, Kizhakkedathu J, Overall CM, Serrano SMT.

J Proteome Res. 2019 Sep 6;18(9):3419-3428. doi: 10.1021/acs.jproteome.9b00325. Epub 2019 Aug 8.

PMID:
31337208
2.

A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies.

Zelanis A, Silva DA, Kitano ES, Liberato T, Fukushima I, Serrano SMT, Tashima AK.

Comp Biochem Physiol Part D Genomics Proteomics. 2019 Sep;31:100599. doi: 10.1016/j.cbd.2019.100599. Epub 2019 May 31.

PMID:
31181499
3.

Comparative analysis of the high molecular mass subproteomes of eight Bothrops snake venoms.

Gren ECK, Kitano ES, Andrade-Silva D, Iwai LK, Reis MS, Menezes MC, Serrano SMT.

Comp Biochem Physiol Part D Genomics Proteomics. 2019 Jun;30:113-121. doi: 10.1016/j.cbd.2019.01.012. Epub 2019 Jan 30.

PMID:
30825662
4.

Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation.

Silva-de-França F, Villas-Boas IM, Serrano SMT, Cogliati B, Chudzinski SAA, Lopes PH, Kitano ES, Okamoto CK, Tambourgi DV.

PLoS Negl Trop Dis. 2019 Jan 18;13(1):e0007017. doi: 10.1371/journal.pntd.0007017. eCollection 2019 Jan.

5.

Early response of C2C12 myotubes to a sub-cytotoxic dose of hemorrhagic metalloproteinase HF3 from Bothrops jararaca venom.

Menezes MC, Kitano ES, Bauer VC, Oliveira AK, Cararo-Lopes E, Nishiyama MY Jr, Zelanis A, Serrano SMT.

J Proteomics. 2019 Apr 30;198:163-176. doi: 10.1016/j.jprot.2018.12.006. Epub 2018 Dec 12.

PMID:
30553073
6.

Proteomic profiling of the proteolytic events in the secretome of the transformed phenotype of melanocyte-derived cells using Terminal Amine Isotopic Labeling of Substrates.

Liberato T, Fukushima I, Kitano ES, Serrano SMT, Chammas R, Zelanis A.

J Proteomics. 2019 Feb 10;192:291-298. doi: 10.1016/j.jprot.2018.09.010. Epub 2018 Sep 26.

PMID:
30267877
7.

Biochemical characterization of venom from Pseudoboa neuwiedii (Neuwied's false boa; Xenodontinae; Pseudoboini).

Torres-Bonilla KA, Andrade-Silva D, Serrano SMT, Hyslop S.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Nov;213:27-38. doi: 10.1016/j.cbpc.2018.06.003. Epub 2018 Jun 30.

PMID:
29966733
8.

Structures of N-Glycans of Bothrops Venoms Revealed as Molecular Signatures that Contribute to Venom Phenotype in Viperid Snakes.

Andrade-Silva D, Ashline D, Tran T, Lopes AS, Travaglia Cardoso SR, Reis MDS, Zelanis A, Serrano SMT, Reinhold V.

Mol Cell Proteomics. 2018 Jul;17(7):1261-1284. doi: 10.1074/mcp.RA118.000748. Epub 2018 May 1.

9.

Leptospira interrogans Secreted Proteases Degrade Extracellular Matrix and Plasma Proteins From the Host.

da Silva LB, Menezes MC, Kitano ES, Oliveira AK, Abreu AG, Souza GO, Heinemann MB, Isaac L, Fraga TR, Serrano SMT, Barbosa AS.

Front Cell Infect Microbiol. 2018 Mar 27;8:92. doi: 10.3389/fcimb.2018.00092. eCollection 2018.

10.

Analysis of the Snake Venom Peptidome.

Serrano SMT, Zelanis A, Kitano ES, Tashima AK.

Methods Mol Biol. 2018;1719:349-358. doi: 10.1007/978-1-4939-7537-2_23.

PMID:
29476523
11.

Clinical assessment and brain findings in a cohort of mothers, fetuses and infants infected with ZIKA virus.

Sanz Cortes M, Rivera AM, Yepez M, Guimaraes CV, Diaz Yunes I, Zarutskie A, Davila I, Shetty A, Mahadev A, Serrano SM, Castillo N, Lee W, Valentine G, Belfort M, Parra G, Mohila C, Aagaard K, Parra Saavedra M.

Am J Obstet Gynecol. 2018 Apr;218(4):440.e1-440.e36. doi: 10.1016/j.ajog.2018.01.012. Epub 2018 Jan 17.

PMID:
29353032
12.

Functional and proteomic comparison of Bothrops jararaca venom from captive specimens and the Brazilian Bothropic Reference Venom.

Farias IB, Morais-Zani K, Serino-Silva C, Sant'Anna SS, Rocha MMTD, Grego KF, Andrade-Silva D, Serrano SMT, Tanaka-Azevedo AM.

J Proteomics. 2018 Mar 1;174:36-46. doi: 10.1016/j.jprot.2017.12.008. Epub 2017 Dec 22.

PMID:
29275044
13.

Signatures of protein expression revealed by secretome analyses of cancer associated fibroblasts and melanoma cell lines.

Liberato T, Pessotti DS, Fukushima I, Kitano ES, Serrano SMT, Zelanis A.

J Proteomics. 2018 Mar 1;174:1-8. doi: 10.1016/j.jprot.2017.12.013. Epub 2017 Dec 22.

PMID:
29275043
14.

Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase.

Freitas-de-Sousa LA, Colombini M, Lopes-Ferreira M, Serrano SMT, Moura-da-Silva AM.

Toxins (Basel). 2017 Aug 2;9(8). pii: E239. doi: 10.3390/toxins9080239.

15.

Phosphosite-specific regulation of the oxidative-stress response of Paracoccidioides brasiliensis: a shotgun phosphoproteomic analysis.

Chaves AF, Castilho DG, Navarro MV, Oliveira AK, Serrano SM, Tashima AK, Batista WL.

Microbes Infect. 2017 Jan;19(1):34-46. doi: 10.1016/j.micinf.2016.08.004. Epub 2016 Aug 30.

PMID:
27590702
16.

Dynamic Rearrangement in Snake Venom Gland Proteome: Insights into Bothrops jararaca Intraspecific Venom Variation.

Augusto-de-Oliveira C, Stuginski DR, Kitano ES, Andrade-Silva D, Liberato T, Fukushima I, Serrano SM, Zelanis A.

J Proteome Res. 2016 Oct 7;15(10):3752-3762. Epub 2016 Sep 12.

PMID:
27575776
17.

Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo.

Branco VG, Iqbal A, Alvarez-Flores MP, Sciani JM, de Andrade SA, Iwai LK, Serrano SM, Chudzinski-Tavassi AM.

Biochim Biophys Acta. 2016 Oct;1864(10):1428-35. doi: 10.1016/j.bbapap.2016.07.011. Epub 2016 Jul 30.

PMID:
27479486
18.

Peptidomics of Acanthoscurria gomesiana spider venom reveals new toxins with potential antimicrobial activity.

Abreu TF, Sumitomo BN, Nishiyama MY Jr, Oliveira UC, Souza GH, Kitano ES, Zelanis A, Serrano SM, Junqueira-de-Azevedo I, Silva PI Jr, Tashima AK.

J Proteomics. 2017 Jan 16;151:232-242. doi: 10.1016/j.jprot.2016.07.012. Epub 2016 Jul 17.

PMID:
27436114
19.

Trends in the Evolution of Snake Toxins Underscored by an Integrative Omics Approach to Profile the Venom of the Colubrid Phalotris mertensi.

Campos PF, Andrade-Silva D, Zelanis A, Paes Leme AF, Rocha MM, Menezes MC, Serrano SM, Junqueira-de-Azevedo Ide L.

Genome Biol Evol. 2016 Aug 16;8(8):2266-87. doi: 10.1093/gbe/evw149.

20.

AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility.

Silva TA, Smuczek B, Valadão IC, Dzik LM, Iglesia RP, Cruz MC, Zelanis A, de Siqueira AS, Serrano SM, Goldberg GS, Jaeger RG, Freitas VM.

Oncotarget. 2016 Aug 2;7(31):49998-50016. doi: 10.18632/oncotarget.10307.

21.

Proteomic and Glycoproteomic Profilings Reveal That Post-translational Modifications of Toxins Contribute to Venom Phenotype in Snakes.

Andrade-Silva D, Zelanis A, Kitano ES, Junqueira-de-Azevedo IL, Reis MS, Lopes AS, Serrano SM.

J Proteome Res. 2016 Aug 5;15(8):2658-75. doi: 10.1021/acs.jproteome.6b00217. Epub 2016 Jul 7.

PMID:
27297130
22.

Recombinant expression of the precursor of the hemorrhagic metalloproteinase HF3 and its non-catalytic domains using a cell-free synthesis system.

Menezes MC, Imbert L, Kitano ES, Vernet T, Serrano SM.

Amino Acids. 2016 Sep;48(9):2205-14. doi: 10.1007/s00726-016-2255-7. Epub 2016 May 21.

PMID:
27209197
23.

Proteome-derived peptide library for the elucidation of the cleavage specificity of HF3, a snake venom metalloproteinase.

Bertholim L, Zelanis A, Oliveira AK, Serrano SM.

Amino Acids. 2016 May;48(5):1331-5. doi: 10.1007/s00726-016-2218-z. Epub 2016 Mar 29.

PMID:
27020778
24.

Proteomic identification of gender molecular markers in Bothrops jararaca venom.

Zelanis A, Menezes MC, Kitano ES, Liberato T, Tashima AK, Pinto AF, Sherman NE, Ho PL, Fox JW, Serrano SM.

J Proteomics. 2016 Apr 29;139:26-37. doi: 10.1016/j.jprot.2016.02.030. Epub 2016 Mar 2.

PMID:
26941108
25.

Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion.

Castiblanco-Valencia MM, Fraga TR, Pagotto AH, Serrano SM, Abreu PA, Barbosa AS, Isaac L.

Immunobiology. 2016 May;221(5):679-89. doi: 10.1016/j.imbio.2016.01.001. Epub 2016 Jan 7.

PMID:
26822552
26.

High-resolution proteomic profiling of spider venom: expanding the toxin diversity of Phoneutria nigriventer venom.

Liberato T, Troncone LRP, Yamashiro ET, Serrano SMT, Zelanis A.

Amino Acids. 2016 Mar;48(3):901-906. doi: 10.1007/s00726-015-2151-6. Epub 2016 Jan 23.

PMID:
26803659
27.

Ontogenetic Variation in Biological Activities of Venoms from Hybrids between Bothrops erythromelas and Bothrops neuwiedi Snakes.

Santoro ML, do Carmo T, Cunha BH, Alves AF, Zelanis A, Serrano SM, Grego KF, Sant'Anna SS, Barbaro KC, Fernandes W.

PLoS One. 2015 Dec 29;10(12):e0145516. doi: 10.1371/journal.pone.0145516. eCollection 2015.

28.

Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species.

Freitas-de-Sousa LA, Amazonas DR, Sousa LF, Sant'Anna SS, Nishiyama MY Jr, Serrano SM, Junqueira-de-Azevedo IL, Chalkidis HM, Moura-da-Silva AM, Mourão RH.

Biochimie. 2015 Nov;118:60-70. doi: 10.1016/j.biochi.2015.08.006. Epub 2015 Aug 12.

29.

New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms.

Kodama RT, Cajado-Carvalho D, Kuniyoshi AK, Kitano ES, Tashima AK, Barna BF, Takakura AC, Serrano SM, Dias-Da-Silva W, Tambourgi DV, Portaro FV.

Biochim Biophys Acta. 2015 Jun;1850(6):1180-7. doi: 10.1016/j.bbagen.2015.02.005. Epub 2015 Feb 14.

30.

Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites.

Zelanis A, Huesgen PF, Oliveira AK, Tashima AK, Serrano SM, Overall CM.

J Proteomics. 2015 Jan 15;113:260-7. doi: 10.1016/j.jprot.2014.10.002. Epub 2014 Oct 14.

PMID:
25452133
31.

Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation.

Bernardoni JL, Sousa LF, Wermelinger LS, Lopes AS, Prezoto BC, Serrano SM, Zingali RB, Moura-da-Silva AM.

PLoS One. 2014 Oct 14;9(10):e109651. doi: 10.1371/journal.pone.0109651. eCollection 2014.

32.

Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms.

Cajado Carvalho D, Kuniyoshi AK, Kodama RT, Oliveira AK, Serrano SM, Tambourgi DV, Portaro FV.

Toxicol Sci. 2014 Dec;142(2):418-26. doi: 10.1093/toxsci/kfu193. Epub 2014 Sep 19.

PMID:
25239630
33.

Proteoforms of the platelet-aggregating enzyme PA-BJ, a serine proteinase from Bothrops jararaca venom.

Yamashiro ET, Oliveira AK, Kitano ES, Menezes MC, Junqueira-de-Azevedo IL, Paes Leme AF, Serrano SM.

Biochim Biophys Acta. 2014 Dec;1844(12):2068-76. doi: 10.1016/j.bbapap.2014.09.012. Epub 2014 Sep 18.

34.

Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia.

Herrera M, Paiva OK, Pagotto AH, Segura A, Serrano SM, Vargas M, Villalta M, Jensen SD, León G, Williams DJ, Gutiérrez JM.

Am J Trop Med Hyg. 2014 Nov;91(5):887-94. doi: 10.4269/ajtmh.14-0333. Epub 2014 Aug 25.

35.

Exploring potential virulence regulators in Paracoccidioides brasiliensis isolates of varying virulence through quantitative proteomics.

Castilho DG, Chaves AF, Xander P, Zelanis A, Kitano ES, Serrano SM, Tashima AK, Batista WL.

J Proteome Res. 2014 Oct 3;13(10):4259-71. doi: 10.1021/pr5002274. Epub 2014 Sep 2.

PMID:
25145636
36.

Interaction of Bothrops jararaca venom metalloproteinases with protein inhibitors.

Asega AF, Oliveira AK, Menezes MC, Neves-Ferreira AG, Serrano SM.

Toxicon. 2014 Mar;80:1-8. doi: 10.1016/j.toxicon.2014.01.001. Epub 2014 Jan 14.

37.

P-I snake venom metalloproteinase is able to activate the complement system by direct cleavage of central components of the cascade.

Pidde-Queiroz G, Magnoli FC, Portaro FC, Serrano SM, Lopes AS, Paes Leme AF, van den Berg CW, Tambourgi DV.

PLoS Negl Trop Dis. 2013 Oct 31;7(10):e2519. doi: 10.1371/journal.pntd.0002519. eCollection 2013.

38.

Rapid purification of serine proteinases from Bothrops alternatus and Bothrops moojeni venoms.

Fernandes de Oliveira LM, Ullah A, Masood R, Zelanis A, Spencer PJ, Serrano SM, Arni RK.

Toxicon. 2013 Dec 15;76:282-90. doi: 10.1016/j.toxicon.2013.10.016. Epub 2013 Oct 17.

39.

Individual variability in the venom proteome of juvenile Bothrops jararaca specimens.

Dias GS, Kitano ES, Pagotto AH, Sant'anna SS, Rocha MM, Zelanis A, Serrano SM.

J Proteome Res. 2013 Oct 4;12(10):4585-98. doi: 10.1021/pr4007393. Epub 2013 Sep 18.

PMID:
23998483
40.

Cotiarinase is a novel prothrombin activator from the venom of Bothrops cotiara.

Kitano ES, Garcia TC, Menezes MC, Tashima AK, Zelanis A, Serrano SM.

Biochimie. 2013 Aug;95(8):1655-9. doi: 10.1016/j.biochi.2013.04.006. Epub 2013 Apr 23.

41.

Generation of a Chinese hamster ovary cell line producing recombinant human glucocerebrosidase.

Novo JB, Morganti L, Moro AM, Paes Leme AF, Serrano SM, Raw I, Ho PL.

J Biomed Biotechnol. 2012;2012:875383. doi: 10.1155/2012/875383. Epub 2012 Oct 3.

42.

The long road of research on snake venom serine proteinases.

Serrano SM.

Toxicon. 2013 Feb;62:19-26. doi: 10.1016/j.toxicon.2012.09.003. Epub 2012 Sep 23. Review.

PMID:
23010164
43.

Peptidomics of three Bothrops snake venoms: insights into the molecular diversification of proteomes and peptidomes.

Tashima AK, Zelanis A, Kitano ES, Ianzer D, Melo RL, Rioli V, Sant'anna SS, Schenberg AC, Camargo AC, Serrano SM.

Mol Cell Proteomics. 2012 Nov;11(11):1245-62. doi: 10.1074/mcp.M112.019331. Epub 2012 Aug 6.

44.

BJ-PI2, a non-hemorrhagic metalloproteinase from Bothrops jararaca snake venom.

da Silva IR, Lorenzetti R, Rennó AL, Baldissera L Jr, Zelanis A, Serrano SM, Hyslop S.

Biochim Biophys Acta. 2012 Nov;1820(11):1809-21. doi: 10.1016/j.bbagen.2012.07.011. Epub 2012 Jul 31.

45.

Do firstborn children have an increased risk of ADHD?

Marín AM, Seco FL, Serrano SM, García SA, Gaviria Gómez AM, Ney I.

J Atten Disord. 2014 Oct;18(7):594-7. doi: 10.1177/1087054712445066. Epub 2012 Jul 23.

PMID:
22826511
46.

A transcriptomic view of the proteome variability of newborn and adult Bothrops jararaca snake venoms.

Zelanis A, Andrade-Silva D, Rocha MM, Furtado MF, Serrano SM, Junqueira-de-Azevedo IL, Ho PL.

PLoS Negl Trop Dis. 2012;6(3):e1554. doi: 10.1371/journal.pntd.0001554. Epub 2012 Mar 13.

47.

Venomics profiling of Thamnodynastes strigatus unveils matrix metalloproteinases and other novel proteins recruited to the toxin arsenal of rear-fanged snakes.

Ching AT, Paes Leme AF, Zelanis A, Rocha MM, Furtado Mde F, Silva DA, Trugilho MR, da Rocha SL, Perales J, Ho PL, Serrano SM, Junqueira-de-Azevedo IL.

J Proteome Res. 2012 Feb 3;11(2):1152-62. doi: 10.1021/pr200876c. Epub 2012 Jan 20.

PMID:
22168127
48.

N-glycome profiling of Bothrops jararaca newborn and adult venoms.

Zelanis A, Serrano SM, Reinhold VN.

J Proteomics. 2012 Jan 4;75(3):774-82. doi: 10.1016/j.jprot.2011.09.017. Epub 2011 Oct 1.

PMID:
21989267
49.

Hemorrhagic activity of HF3, a snake venom metalloproteinase: insights from the proteomic analysis of mouse skin and blood plasma.

Paes Leme AF, Sherman NE, Smalley DM, Sizukusa LO, Oliveira AK, Menezes MC, Fox JW, Serrano SM.

J Proteome Res. 2012 Jan 1;11(1):279-91. doi: 10.1021/pr2006439. Epub 2011 Oct 27.

PMID:
21939285
50.

Bothrops jararaca venom proteome rearrangement upon neonate to adult transition.

Zelanis A, Tashima AK, Pinto AF, Paes Leme AF, Stuginski DR, Furtado MF, Sherman NE, Ho PL, Fox JW, Serrano SM.

Proteomics. 2011 Nov;11(21):4218-28. doi: 10.1002/pmic.201100287. Epub 2011 Sep 16.

PMID:
21928397

Supplemental Content

Loading ...
Support Center