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Items: 1 to 50 of 57

1.

Acute salt loading induces sympathetic nervous system overdrive in mice lacking salt-inducible kinase 1 (SIK1).

Pires NM, Igreja B, Serrão MP, Matias EF, Moura E, António T, Campos FL, Brion L, Bertorello A, Soares-da-Silva P.

Hypertens Res. 2019 Aug;42(8):1114-1124. doi: 10.1038/s41440-019-0249-z. Epub 2019 Mar 20.

PMID:
30894696
2.

Effects of nepicastat upon dopamine-β-hydroxylase activity and dopamine and norepinephrine levels in the rat left ventricle, kidney, and adrenal gland.

Catelas DN, Serrão MP, Soares-Da-Silva P.

Clin Exp Hypertens. 2020;42(2):118-125. doi: 10.1080/10641963.2019.1583245. Epub 2019 Mar 1.

PMID:
30821508
3.

Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors.

Pinheiro SD, Serrão MP, Silva T, Borges F, Soares-da-Silva P.

Eur J Pharmacol. 2019 Mar 15;847:53-60. doi: 10.1016/j.ejphar.2019.01.027. Epub 2019 Jan 24.

PMID:
30685433
4.

Antihypertensive effect of etamicastat in dopamine D2 receptor-deficient mice.

Armando I, Asico LD, Wang X, Jones JE, Serrão MP, Cuevas S, Grandy DK, Soares-da-Silva P, Jose PA.

Hypertens Res. 2018 Jul;41(7):489-498. doi: 10.1038/s41440-018-0041-5. Epub 2018 Apr 13.

5.

Catechol-O-methyltransferase activity in erythrocytes from patients with eating disorders.

Amorim-Barbosa T, Serrão MP, Brandão I, Vieira-Coelho MA.

Eat Weight Disord. 2016 Jun;21(2):221-7. doi: 10.1007/s40519-015-0213-0. Epub 2015 Aug 22.

PMID:
26296436
6.

Blood pressure decrease in spontaneously hypertensive rats folowing renal denervation or dopamine β-hydroxylase inhibition with etamicastat.

Pires NM, Igreja B, Moura E, Wright LC, Serrão MP, Soares-da-Silva P.

Hypertens Res. 2015 Sep;38(9):605-12. doi: 10.1038/hr.2015.50. Epub 2015 Apr 9.

PMID:
25854989
7.

Renalase regulates peripheral and central dopaminergic activities.

Quelhas-Santos J, Serrão MP, Soares-Silva I, Fernandes-Cerqueira C, Simões-Silva L, Pinho MJ, Remião F, Sampaio-Maia B, Desir GV, Pestana M.

Am J Physiol Renal Physiol. 2015 Jan 15;308(2):F84-91. doi: 10.1152/ajprenal.00274.2014. Epub 2014 Nov 19.

8.

Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis.

Magina S, Vieira-Coelho MA, Moura E, Serrão MP, Piscitelli F, Moura D, Di Marzo V.

Br J Dermatol. 2014 Jul;171(1):198-201. doi: 10.1111/bjd.12916. Epub 2014 Jul 17. No abstract available.

PMID:
24641781
9.

Catechol-O-methyltransferase activity in psoriasis patients treated with psoralen plus ultraviolet A therapy.

Souteiro P, Vieira-Coelho MA, Serrão MP, Magina S.

Photodermatol Photoimmunol Photomed. 2013 Oct;29(5):227-32. doi: 10.1111/phpp.12058.

PMID:
24001377
10.

Catechol-O-methyltransferase activity is higher in psoriasis patients and is down-regulated by narrowband ultraviolet B treatment.

Magina S, Moura E, Serrão MP, Moura D, Vieira-Coelho MA.

Eur J Dermatol. 2013 Jan-Feb;23(1):49-52. doi: 10.1684/ejd.2012.1912.

PMID:
23399536
11.

α2C-Adrenoceptors modulate L-DOPA uptake in opossum kidney cells and in the mouse kidney.

Moura E, Silva E, Serrão MP, Afonso J, Kozmus CE, Vieira-Coelho MA.

Am J Physiol Renal Physiol. 2012 Oct;303(7):F928-38. doi: 10.1152/ajprenal.00217.2011. Epub 2012 Aug 1.

12.

Long-term food restriction attenuates age-related changes in the expression of renal aldosterone-sensitive sodium transporters in Wistar-Kyoto rats: a comparison with SHR.

Pinto V, Pinho MJ, Silva E, Simão S, Igreja B, Afonso J, Serrão MP, Gomes P, Soares-da-Silva P.

Exp Gerontol. 2012 Aug;47(8):644-53. doi: 10.1016/j.exger.2012.05.022. Epub 2012 Jun 9.

PMID:
22687288
13.

Ultraviolet B radiation differentially modifies catechol-O-methyltransferase activity in keratinocytes and melanoma cells.

Magina S, Vieira-Coelho MA, Serrão MP, Kosmus C, Moura E, Moura D.

Photodermatol Photoimmunol Photomed. 2012 Jun;28(3):137-41. doi: 10.1111/j.1600-0781.2012.00653.x.

PMID:
22548395
14.

Influence of dietary supplementation with dextrin or oligofructose on the hepatic redox balance in rats.

Kozmus CE, Moura E, Serrão MP, Real H, Guimarães JT, Guedes-de-Pinho P, Duarte BP, Marques F, Martins MJ, Vieira-Coelho MA.

Mol Nutr Food Res. 2011 Nov;55(11):1735-9. doi: 10.1002/mnfr.201100287. Epub 2011 Sep 21.

PMID:
21936050
15.

Age-related changes in the renal dopaminergic system and expression of renal amino acid transporters in WKY and SHR rats.

Pinto V, Amaral J, Silva E, Simão S, Cabral JM, Afonso J, Serrão MP, Gomes P, Pinho MJ, Soares-da-Silva P.

Mech Ageing Dev. 2011 Jun-Jul;132(6-7):298-304. doi: 10.1016/j.mad.2011.06.003. Epub 2011 Jun 15.

PMID:
21699911
16.

α₂-Adrenoceptor-mediated inhibition of catecholamine release from the adrenal medulla of spontaneously hypertensive rats is preserved in the early stages of hypertension.

Moura E, Pinto CE, Caló A, Serrão MP, Afonso J, Vieira-Coelho MA.

Basic Clin Pharmacol Toxicol. 2011 Oct;109(4):253-60. doi: 10.1111/j.1742-7843.2011.00712.x. Epub 2011 May 26.

17.

Age-dependent effect of ouabain on renal Na+,K+-ATPase.

Silva E, Serrão MP, Soares-da-Silva P.

Life Sci. 2011 Apr 11;88(15-16):719-24. doi: 10.1016/j.lfs.2011.02.012. Epub 2011 Feb 19.

PMID:
21338612
18.

Age-related changes in renal expression of oxidant and antioxidant enzymes and oxidative stress markers in male SHR and WKY rats.

Simão S, Gomes P, Pinto V, Silva E, Amaral JS, Igreja B, Afonso J, Serrão MP, Pinho MJ, Soares-da-Silva P.

Exp Gerontol. 2011 Jun;46(6):468-74. doi: 10.1016/j.exger.2011.02.003. Epub 2011 Feb 18.

PMID:
21316443
19.

Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect.

Magina S, Esteves-Pinto C, Moura E, Serrão MP, Moura D, Petrosino S, Di Marzo V, Vieira-Coelho MA.

Arch Dermatol Res. 2011 Apr;303(3):201-10. doi: 10.1007/s00403-011-1126-z. Epub 2011 Feb 5.

PMID:
21298280
20.

LAT1 overexpression and function compensates downregulation of ASCT2 in an in vitro model of renal proximal tubule cell ageing.

Pinho MJ, Cabral JM, Silva E, Serrão MP, Soares-da-Silva P.

Mol Cell Biochem. 2011 Mar;349(1-2):107-16. doi: 10.1007/s11010-010-0665-5. Epub 2010 Dec 2.

PMID:
21125315
21.

Renal aging in WKY rats: changes in Na+,K+ -ATPase function and oxidative stress.

Silva E, Pinto V, Simão S, Serrão MP, Afonso J, Amaral J, Pinho MJ, Gomes P, Soares-da-Silva P.

Exp Gerontol. 2010 Dec;45(12):977-83. doi: 10.1016/j.exger.2010.09.012. Epub 2010 Sep 29.

PMID:
20883770
22.

Adrenal α2-adrenergic receptors in the aging normotensive and spontaneously hypertensive rat.

Moura E, Pinto CE, Serrão MP, Afonso J, Vieira-Coelho MA.

Neurobiol Aging. 2012 May;33(5):969-78. doi: 10.1016/j.neurobiolaging.2010.06.021. Epub 2010 Aug 5.

PMID:
20691504
23.

Aging increases oxidative stress and renal expression of oxidant and antioxidant enzymes that are associated with an increased trend in systolic blood pressure.

Gomes P, Simão S, Silva E, Pinto V, Amaral JS, Afonso J, Serrão MP, Pinho MJ, Soares-da-Silva P.

Oxid Med Cell Longev. 2009 Jul-Aug;2(3):138-45.

24.

Effect of (-)-Delta(9)-tetrahydrocannabinoid on the hepatic redox state of mice.

Pinto CE, Moura E, Serrão MP, Martins MJ, Vieira-Coelho MA.

Braz J Med Biol Res. 2010 Apr;43(4):325-9. doi: 10.1590/S0100-879X2010007500015. Epub 2010 Mar 12.

25.

Catecholamine synthesis and metabolism in the central nervous system of mice lacking alpha-adrenoceptor subtypes.

Vieira-Coelho MA, Serrão MP, Afonso J, Pinto CE, Moura E.

Br J Pharmacol. 2009 Oct;158(3):726-37. doi: 10.1111/j.1476-5381.2009.00375.x. Epub 2009 Aug 24.

26.

Effect of clonidine on tyrosine hydroxylase activity in the adrenal medulla and brain of spontaneously hypertensive rats.

Moura E, Afonso J, Serrão MP, Vieira-Coelho MA.

Basic Clin Pharmacol Toxicol. 2009 Feb;104(2):113-21. doi: 10.1111/j.1742-7843.2008.00339.x. Epub 2008 Dec 5.

27.

Overexpression of non-functional LAT1/4F2hc in renal proximal tubular epithelial cells from the spontaneous hypertensive rat.

Pinho MJ, Serrão MP, Jose PA, Soares-da-Silva P.

Cell Physiol Biochem. 2007;20(5):535-48.

28.

Organ specific underexpression renal of Na+-dependent B0AT1 in the SHR correlates positively with overexpression of NHE3 and salt intake.

Pinho MJ, Serrão MP, José PA, Soares-da-Silva P.

Mol Cell Biochem. 2007 Dec;306(1-2):9-18. Epub 2007 Jul 24.

PMID:
17646927
29.

Underexpression of the Na+-dependent neutral amino acid transporter ASCT2 in the spontaneously hypertensive rat kidney.

Pinho MJ, Pinto V, Serrão MP, Jose PA, Soares-da-Silva P.

Am J Physiol Regul Integr Comp Physiol. 2007 Jul;293(1):R538-47. Epub 2007 May 2.

30.

High-salt intake and the renal expression of amino acid transporters in spontaneously hypertensive rats.

Pinho MJ, Serrão MP, Soares-da-Silva P.

Am J Physiol Renal Physiol. 2007 May;292(5):F1452-63. Epub 2007 Jan 30.

31.

Apical and basolateral 4F2hc and the amino acid exchange of L-DOPA in renal LLC-PK1 cells.

Soares-da-Silva P, Serrão MP.

Amino Acids. 2005 Nov;29(3):213-9. Epub 2005 Sep 5.

PMID:
16136276
32.

Cloning and gene silencing of LAT2, the L-3,4-dihydroxyphenylalanine (L-DOPA) transporter, in pig renal LLC-PK1 epithelial cells.

Soares-Da-Silva P, Serrão MP, Pinho MJ, Bonifácio MJ.

FASEB J. 2004 Oct;18(13):1489-98.

PMID:
15466357
33.
34.

Over-expression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells.

Pinho MJ, Serrão MP, Gomes P, Hopfer U, Jose PA, Soares-da-Silva P.

Kidney Int. 2004 Jul;66(1):216-26.

35.

Organ-specific overexpression of renal LAT2 and enhanced tubular L-DOPA uptake precede the onset of hypertension.

Pinho MJ, Gomes P, Serrão MP, Bonifácio MJ, Soares-da-Silva P.

Hypertension. 2003 Oct;42(4):613-8. Epub 2003 Sep 15.

PMID:
12975385
36.

The L-3,4-dihydroxyphenylalanine transporter in human and rat epithelial intestinal cells is a type 2 hetero amino acid exchanger.

Fraga S, Serrão MP, Soares-da-Silva P.

Eur J Pharmacol. 2002 Apr 26;441(3):127-35.

PMID:
12063083
37.

Regulation of apical transporter of L-DOPA in human intestinal Caco-2 cells.

Fraga S, Sampaio-Maia B, Serrão MP, Soares-da-Silva P.

Acta Physiol Scand. 2002 Jun;175(2):103-11.

PMID:
12028130
38.
39.

Impaired synthesis or cellular storage of norepinephrine, dopamine, and 5-hydroxytryptamine in human inflammatory bowel disease.

Magro F, Vieira-Coelho MA, Fraga S, Serrão MP, Veloso FT, Ribeiro T, Soares-da-Silva P.

Dig Dis Sci. 2002 Jan;47(1):216-24.

PMID:
11837726
40.

D1-like dopamine receptor activation and natriuresis by nitrocatechol COMT inhibitors.

Vieira-Coelho MA, Gomes P, Serrão MP, Soares-da-Silva P.

Kidney Int. 2001 May;59(5):1683-94.

41.

Regulatory pathways and uptake of L-DOPA by capillary cerebral endothelial cells, astrocytes, and neuronal cells.

Sampaio-Maia B, Serrão MP, Soares-da-Silva P.

Am J Physiol Cell Physiol. 2001 Feb;280(2):C333-42.

42.

Food deprivation increases alpha(2)-adrenoceptor-mediated modulation of jejunal epithelial transport in young and adult rats.

Lucas-Teixeira V, Vieira-Coelho MA, Serrão MP, Soares-da-Silva P.

J Nutr. 2000 Oct;130(10):2461-6.

PMID:
11015473
43.

Molecular modulation of inward and outward apical transporters of L-dopa in LLC-PK(1) cells.

Soares-Da-Silva P, Serrão MP.

Am J Physiol Renal Physiol. 2000 Oct;279(4):F736-46.

44.

Response of jejunal Na+, K+-ATPase to 5-hydroxytryptamine in young and adult rats: effect of fasting and refeeding.

Lucas-Teixeira V, Serrão MP, Soares-Da-Silva P.

Acta Physiol Scand. 2000 Jun;169(2):167-72.

PMID:
10848647
45.
46.

Effect of salt intake on jejunal dopamine, Na+,K+-ATPase activity and electrolyte transport.

Lucas-Teixeira V, Serrão MP, Soares-Da-Silva P.

Acta Physiol Scand. 2000 Jan;168(1):225-31.

PMID:
10691805
47.

Aging, high salt intake, and renal dopaminergic activity in Fischer 344 rats.

Vieira-Coelho MA, Hussain T, Kansra V, Serrao MP, Guimaraes JT, Pestana M, Soares-Da-Silva P, Lokhandwala MF.

Hypertension. 1999 Oct;34(4 Pt 1):666-72.

PMID:
10523344
48.

Caco-2 cells in culture synthesize and degrade dopamine and 5-hydroxytryptamine: a comparison with rat jejunal epithelial cells.

Vieira-Coelho MA, Teixeira VL, Guimarães JT, Serrão MP, Soares-da-Silva P.

Life Sci. 1999;64(1):69-81.

PMID:
10027744
49.

L-3,4-dihydroxyphenylalanine and L-5-hydroxytryptophan share the same transporter in Opossum kidney cells.

Gomes P, Serrão MP, Vieira-Coelho MA, Soares-da-Silva P.

Int J Biochem Cell Biol. 1998 Feb;30(2):243-50.

PMID:
9608678
50.

Apical and basolateral uptake and intracellular fate of dopamine precursor L-dopa in LLC-PK1 cells.

Soares-Da-Silva P, Serrão MP, Vieira-Coelho MA.

Am J Physiol. 1998 Feb;274(2):F243-51. doi: 10.1152/ajprenal.1998.274.2.F243.

PMID:
9486218

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