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Items: 1 to 50 of 68

1.

Rhomboid-Like-2 Intramembrane Protease Mediates Metalloprotease-Independent Regulation of Cadherins.

Battistini C, Rehman M, Avolio M, Arduin A, Valdembri D, Serini G, Tamagnone L.

Int J Mol Sci. 2019 Nov 27;20(23). pii: E5958. doi: 10.3390/ijms20235958.

2.

Kinesin-2 Controls the Motility of RAB5 Endosomes and Their Association with the Spindle in Mitosis.

Pupo E, Avanzato D, Scianna M, Oldani A, Serini G, Lanzetti L.

Int J Mol Sci. 2018 Aug 30;19(9). pii: E2575. doi: 10.3390/ijms19092575.

3.

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.

Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G.

Sci Transl Med. 2018 May 23;10(442). pii: eaah4807. doi: 10.1126/scitranslmed.aah4807. Erratum in: Sci Transl Med. 2018 Jul 25;10(451):.

4.

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

Regano D, Visintin A, Clapero F, Bussolino F, Valdembri D, Maione F, Serini G, Giraudo E.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1710-1721. doi: 10.1161/ATVBAHA.117.308226. Epub 2017 Jul 20.

5.

TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.

Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Pla AF.

J Cell Biol. 2017 Jul 3;216(7):2107-2130. doi: 10.1083/jcb.201506024. Epub 2017 May 26.

6.

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.

Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D.

Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546.

7.

An Electrical Impedance-Based Method for Quantitative Real-Time Analysis of Semaphorin-Elicited Endothelial Cell Collapse.

Camillo C, Gioelli N, Bussolino F, Serini G.

Methods Mol Biol. 2017;1493:195-207.

PMID:
27787852
8.

Class 3 semaphorins in cardiovascular development.

Valdembri D, Regano D, Maione F, Giraudo E, Serini G.

Cell Adh Migr. 2016 Nov;10(6):641-651. Epub 2016 Jul 20. Review.

9.

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism.

Torchiaro E, Lorenzato A, Olivero M, Valdembri D, Gagliardi PA, Gai M, Erriquez J, Serini G, Di Renzo MF.

Oncotarget. 2016 Jan 5;7(1):712-28. doi: 10.18632/oncotarget.6412.

10.

Bad vessels beware! Semaphorins will sort you out!

Serini G, Tamagnone L.

EMBO Mol Med. 2015 Oct;7(10):1251-3. doi: 10.15252/emmm.201505551. No abstract available.

11.

Linifanib: current status and future potential in cancer therapy.

Aversa C, Leone F, Zucchini G, Serini G, Geuna E, Milani A, Valdembri D, Martinello R, Montemurro F.

Expert Rev Anticancer Ther. 2015 Jun;15(6):677-87. doi: 10.1586/14737140.2015.1042369. Epub 2015 May 2. Review.

PMID:
25936222
12.

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain RK, Serini G, Bussolino F, Primo L.

Nat Cell Biol. 2014 Oct;16(10):931-41, 1-8. doi: 10.1038/ncb3036. Epub 2014 Sep 14.

13.

The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration.

Palamidessi A, Frittoli E, Ducano N, Offenhauser N, Sigismund S, Kajiho H, Parazzoli D, Oldani A, Gobbi M, Serini G, Di Fiore PP, Scita G, Lanzetti L.

Curr Biol. 2013 Dec 2;23(23):2355-64. doi: 10.1016/j.cub.2013.09.060. Epub 2013 Nov 14.

14.

Class 3 semaphorin in angiogenesis and lymphangiogenesis.

Bussolino F, Giraudo E, Serini G.

Chem Immunol Allergy. 2014;99:71-88. doi: 10.1159/000353315. Epub 2013 Oct 17. Review.

PMID:
24217603
15.

Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures.

Cerruti B, Puliafito A, Shewan AM, Yu W, Combes AN, Little MH, Chianale F, Primo L, Serini G, Mostov KE, Celani A, Gamba A.

J Cell Biol. 2013 Oct 28;203(2):359-72. doi: 10.1083/jcb.201305044. Epub 2013 Oct 21.

16.

Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind MET.

Basilico C, Pennacchietti S, Vigna E, Chiriaco C, Arena S, Bardelli A, Valdembri D, Serini G, Michieli P.

Clin Cancer Res. 2013 May 1;19(9):2381-92. doi: 10.1158/1078-0432.CCR-12-3459. Epub 2013 Mar 26.

17.

Neuropilin-1 identifies a subset of bone marrow Gr1- monocytes that can induce tumor vessel normalization and inhibit tumor growth.

Carrer A, Moimas S, Zacchigna S, Pattarini L, Zentilin L, Ruozi G, Mano M, Sinigaglia M, Maione F, Serini G, Giraudo E, Bussolino F, Giacca M.

Cancer Res. 2012 Dec 15;72(24):6371-81. doi: 10.1158/0008-5472.CAN-12-0762. Epub 2012 Dec 7.

18.

Class 3 semaphorins: physiological vascular normalizing agents for anti-cancer therapy.

Serini G, Bussolino F, Maione F, Giraudo E.

J Intern Med. 2013 Feb;273(2):138-55. doi: 10.1111/joim.12017. Review.

19.

Neuropilin-1-dependent regulation of EGF-receptor signaling.

Rizzolio S, Rabinowicz N, Rainero E, Lanzetti L, Serini G, Norman J, Neufeld G, Tamagnone L.

Cancer Res. 2012 Nov 15;72(22):5801-11. doi: 10.1158/0008-5472.CAN-12-0995. Epub 2012 Sep 17.

20.

Regulation of adhesion site dynamics by integrin traffic.

Valdembri D, Serini G.

Curr Opin Cell Biol. 2012 Oct;24(5):582-91. doi: 10.1016/j.ceb.2012.08.004. Epub 2012 Sep 13. Review.

PMID:
22981739
21.

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.

Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, Lanzetti L, Bussolino F, Ivaska J, Serini G.

Cell Res. 2012 Oct;22(10):1479-501. doi: 10.1038/cr.2012.110. Epub 2012 Jul 24.

22.

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice.

Maione F, Capano S, Regano D, Zentilin L, Giacca M, Casanovas O, Bussolino F, Serini G, Giraudo E.

J Clin Invest. 2012 May;122(5):1832-48. doi: 10.1172/JCI58976. Epub 2012 Apr 9.

23.

A bistable model of cell polarity.

Semplice M, Veglio A, Naldi G, Serini G, Gamba A.

PLoS One. 2012;7(2):e30977. doi: 10.1371/journal.pone.0030977. Epub 2012 Feb 23.

24.

The vesicular SNARE Synaptobrevin is required for Semaphorin 3A axonal repulsion.

Zylbersztejn K, Petkovic M, Burgo A, Deck M, Garel S, Marcos S, Bloch-Gallego E, Nothias F, Serini G, Bagnard D, Binz T, Galli T.

J Cell Biol. 2012 Jan 9;196(1):37-46. doi: 10.1083/jcb.201106113. Epub 2012 Jan 2.

25.

Nervous vascular parallels: axon guidance and beyond.

Arese M, Serini G, Bussolino F.

Int J Dev Biol. 2011;55(4-5):439-45. doi: 10.1387/ijdb.103242ma. Review.

26.

Regulation of integrins by conformation and traffic: it takes two to tango.

Valdembri D, Sandri C, Santambrogio M, Serini G.

Mol Biosyst. 2011 Sep;7(9):2539-46. doi: 10.1039/c1mb05066d. Epub 2011 Jul 15. Review.

PMID:
21761076
27.

Increasing traffic on vascular routes.

Santambrogio M, Valdembri D, Serini G.

Mol Aspects Med. 2011 Apr;32(2):112-22. doi: 10.1016/j.mam.2011.04.003. Epub 2011 Apr 23. Review.

PMID:
21536065
28.

Angiogenesis: a balancing act between integrin activation and inhibition?

Bussolino F, Caccavari F, Valdembri D, Serini G.

Eur Cytokine Netw. 2009 Dec;20(4):191-6. doi: 10.1684/ecn.2009.0168. Review.

29.

Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.

Chianale F, Rainero E, Cianflone C, Bettio V, Pighini A, Porporato PE, Filigheddu N, Serini G, Sinigaglia F, Baldanzi G, Graziani A.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4182-7. doi: 10.1073/pnas.0908326107. Epub 2010 Feb 16.

30.

Integrin signaling and lung cancer.

Caccavari F, Valdembri D, Sandri C, Bussolino F, Serini G.

Cell Adh Migr. 2010 Jan-Mar;4(1):124-9. Epub 2010 Jan 16. Review.

31.

Symmetry breaking mechanism for epithelial cell polarization.

Veglio A, Gamba A, Nicodemi M, Bussolino F, Serini G.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Sep;80(3 Pt 1):031919. Epub 2009 Sep 29.

PMID:
19905158
32.

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models.

Maione F, Molla F, Meda C, Latini R, Zentilin L, Giacca M, Seano G, Serini G, Bussolino F, Giraudo E.

J Clin Invest. 2009 Nov;119(11):3356-72. doi: 10.1172/JCI36308. Epub 2009 Oct 5.

33.

Semaphorins and tumor angiogenesis.

Serini G, Maione F, Giraudo E, Bussolino F.

Angiogenesis. 2009;12(2):187-93. doi: 10.1007/s10456-009-9138-4. Epub 2009 Mar 6. Review. Erratum in: Angiogenesis. 2009;12(2):195. Giraudo, Enrico [added].

PMID:
19266292
34.

Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

Valdembri D, Caswell PT, Anderson KI, Schwarz JP, König I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, Serini G.

PLoS Biol. 2009 Jan 27;7(1):e25. doi: 10.1371/journal.pbio.1000025.

35.

Microenvironment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1.

Gualandris A, Noghero A, Geuna M, Arese M, Valdembri D, Serini G, Bussolino F.

FASEB J. 2009 Jan;23(1):68-78. doi: 10.1096/fj.08-112847. Epub 2008 Aug 29.

PMID:
18757501
36.

AP-2alpha and AP-2gamma regulate tumor progression via specific genetic programs.

Orso F, Penna E, Cimino D, Astanina E, Maione F, Valdembri D, Giraudo E, Serini G, Sismondi P, De Bortoli M, Taverna D.

FASEB J. 2008 Aug;22(8):2702-14. doi: 10.1096/fj.08-106492. Epub 2008 Apr 28.

PMID:
18443366
37.

Integrins team up with tyrosine kinase receptors and plexins to control angiogenesis.

Serini G, Napione L, Bussolino F.

Curr Opin Hematol. 2008 May;15(3):235-42. doi: 10.1097/MOH.0b013e3282fa745b. Review.

PMID:
18391791
38.

Besides adhesion: new perspectives of integrin functions in angiogenesis.

Serini G, Napione L, Arese M, Bussolino F.

Cardiovasc Res. 2008 May 1;78(2):213-22. doi: 10.1093/cvr/cvn045. Epub 2008 Feb 19. Review.

PMID:
18285512
39.

Integrins: a flexible platform for endothelial vascular tyrosine kinase receptors.

Napione L, Cascone I, Mitola S, Serini G, Bussolino F.

Autoimmun Rev. 2007 Nov;7(1):18-22. doi: 10.1016/j.autrev.2007.03.007. Epub 2007 Apr 3. Review.

PMID:
17967720
40.

A simulation environment for directional sensing as a phase separation process.

de Candia A, Gamba A, Cavalli F, Coniglio A, Di Talia S, Bussolino F, Serini G.

Sci STKE. 2007 Mar 20;2007(378):pl1.

PMID:
17374853
41.

Embryonic cleavage modeling as a computational approach to sphere packing problem.

Zammataro L, Serini G, Rowland T, Bussolino F.

J Theor Biol. 2007 Mar 7;245(1):77-82. Epub 2006 Oct 4.

PMID:
17087975
42.

Semaphoring vascular morphogenesis.

Bussolino F, Valdembri D, Caccavari F, Serini G.

Endothelium. 2006 Mar-Apr;13(2):81-91. Review.

PMID:
16728327
43.

Role of repulsive factors in vascularization dynamics.

Di Talia S, Gamba A, Lamberti F, Serini G.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Apr;73(4 Pt 1):041917. Epub 2006 Apr 14.

PMID:
16711846
44.

Loss of inhibitory semaphorin 3A (SEMA3A) autocrine loops in bone marrow endothelial cells of patients with multiple myeloma.

Vacca A, Scavelli C, Serini G, Di Pietro G, Cirulli T, Merchionne F, Ribatti D, Bussolino F, Guidolin D, Piaggio G, Bacigalupo A, Dammacco F.

Blood. 2006 Sep 1;108(5):1661-7. Epub 2006 May 9.

PMID:
16684957
45.

Integrins and angiogenesis: a sticky business.

Serini G, Valdembri D, Bussolino F.

Exp Cell Res. 2006 Mar 10;312(5):651-8. Epub 2005 Dec 2. Review.

PMID:
16325811
46.

Diffusion-limited phase separation in eukaryotic chemotaxis.

Gamba A, de Candia A, Di Talia S, Coniglio A, Bussolino F, Serini G.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):16927-32. Epub 2005 Nov 16.

47.

Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1.

Cascone I, Napione L, Maniero F, Serini G, Bussolino F.

J Cell Biol. 2005 Sep 12;170(6):993-1004.

48.

Sema4D induces angiogenesis through Met recruitment by Plexin B1.

Conrotto P, Valdembri D, Corso S, Serini G, Tamagnone L, Comoglio PM, Bussolino F, Giordano S.

Blood. 2005 Jun 1;105(11):4321-9. Epub 2005 Jan 4.

PMID:
15632204
49.

Common cues in vascular and axon guidance.

Serini G, Bussolino F.

Physiology (Bethesda). 2004 Dec;19:348-54. Review.

50.

Cell directional persistence [corrected] and chemotaxis in vascular morphogenesis.

Ambrosi D, Gamba A, Serini G.

Bull Math Biol. 2004 Nov;66(6):1851-73. Erratum in: Bull Math Biol. 2005 Jan;67(1):195.

PMID:
15522357

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