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Items: 1 to 50 of 489

1.

Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice.

Zhang L, Terrando N, Xu ZZ, Bang S, Jordt SE, Maixner W, Serhan CN, Ji RR.

Front Pharmacol. 2018 May 1;9:412. doi: 10.3389/fphar.2018.00412. eCollection 2018.

2.

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators.

Serhan CN, Levy BD.

J Clin Invest. 2018 Jul 2;128(7):2657-2669. doi: 10.1172/JCI97943. Epub 2018 May 14.

3.

Identification of proresolving and inflammatory lipid mediators in human psoriasis.

Sorokin AV, Norris PC, English JT, Dey AK, Chaturvedi A, Baumer Y, Silverman J, Playford MP, Serhan CN, Mehta NN.

J Clin Lipidol. 2018 Jul - Aug;12(4):1047-1060. doi: 10.1016/j.jacl.2018.03.091. Epub 2018 Apr 6.

PMID:
29730187
4.

Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells.

Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Exp Eye Res. 2018 Aug;173:64-72. doi: 10.1016/j.exer.2018.04.015. Epub 2018 Apr 25.

PMID:
29702100
5.

Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology.

Dalli J, Serhan CN.

Br J Pharmacol. 2018 Apr 21. doi: 10.1111/bph.14336. [Epub ahead of print] Review.

PMID:
29679485
6.

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration.

de la Rosa X, Norris PC, Chiang N, Rodriguez AR, Spur BW, Serhan CN.

Am J Pathol. 2018 Apr;188(4):950-966. doi: 10.1016/j.ajpath.2018.01.004.

PMID:
29571326
7.

Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.

Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN, Gilroy DW.

JCI Insight. 2018 Mar 22;3(6). pii: 94463. doi: 10.1172/jci.insight.94463. [Epub ahead of print]

8.

Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair.

Hellmann J, Sansbury BE, Wong B, Li X, Singh M, Nuutila K, Chiang N, Eriksson E, Serhan CN, Spite M.

J Invest Dermatol. 2018 Mar 17. pii: S0022-202X(18)31728-7. doi: 10.1016/j.jid.2018.03.1498. [Epub ahead of print]

PMID:
29559341
9.

Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues.

Norris PC, Serhan CN.

Biochem Biophys Res Commun. 2018 Mar 15. pii: S0006-291X(18)30511-4. doi: 10.1016/j.bbrc.2018.03.037. [Epub ahead of print]

PMID:
29524409
10.

15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia.

Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD.

J Immunol. 2018 Apr 15;200(8):2757-2766. doi: 10.4049/jimmunol.1602090. Epub 2018 Mar 9.

PMID:
29523657
11.

Splenic leukocytes define the resolution of inflammation in heart failure.

Halade GV, Norris PC, Kain V, Serhan CN, Ingle KA.

Sci Signal. 2018 Mar 6;11(520). pii: eaao1818. doi: 10.1126/scisignal.aao1818.

PMID:
29511119
12.

Author Correction: ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance.

Sima C, Montero E, Nguyen D, Freire M, Norris P, Serhan CN, Van Dyke TE.

Sci Rep. 2018 Mar 2;8(1):4143. doi: 10.1038/s41598-018-22520-5.

13.

New maresin conjugates in tissue regeneration pathway counters leukotriene D4-stimulated vascular responses.

Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW, Serhan CN.

FASEB J. 2018 Jul;32(7):4043-4052. doi: 10.1096/fj.201701493R. Epub 2018 Feb 28.

PMID:
29490167
14.

Immune responsive resolvin D1 programs myocardial infarction-induced cardiorenal syndrome in heart failure.

Halade GV, Kain V, Serhan CN.

FASEB J. 2018 Jul;32(7):3717-3729. doi: 10.1096/fj.201701173RR. Epub 2018 Feb 13.

PMID:
29455574
15.

Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation.

Winkler JW, Libreros S, De La Rosa X, Sansbury BE, Norris PC, Chiang N, Fichtner D, Keyes GS, Wourms N, Spite M, Serhan CN.

J Leukoc Biol. 2018 Jan 29. doi: 10.1002/JLB.3MI0617-254R. [Epub ahead of print]

PMID:
29377345
16.

Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis.

Dalli J, Colas RA, Walker ME, Serhan CN.

Methods Mol Biol. 2018;1730:59-72. doi: 10.1007/978-1-4939-7592-1_4.

PMID:
29363065
17.

Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2.

Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos Dos Santos F, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN, Tanowitz HB.

Infect Immun. 2018 Mar 22;86(4). pii: e00688-17. doi: 10.1128/IAI.00688-17. Print 2018 Apr.

PMID:
29358332
18.

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity.

Werz O, Gerstmeier J, Libreros S, De la Rosa X, Werner M, Norris PC, Chiang N, Serhan CN.

Nat Commun. 2018 Jan 4;9(1):59. doi: 10.1038/s41467-017-02538-5.

19.

Potent Anti-Inflammatory and Pro-Resolving Effects of Anabasum in a Human Model of Self-Resolving Acute Inflammation.

Motwani MP, Bennett F, Norris PC, Maini AA, George MJ, Newson J, Henderson A, Hobbs AJ, Tepper M, White B, Serhan CN, MacAllister R, Gilroy DW.

Clin Pharmacol Ther. 2017 Dec 14. doi: 10.1002/cpt.980. [Epub ahead of print]

PMID:
29238967
20.

Resolvins suppress tumor growth and enhance cancer therapy.

Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S, Panigrahy D.

J Exp Med. 2018 Jan 2;215(1):115-140. doi: 10.1084/jem.20170681. Epub 2017 Nov 30.

21.

Pro-Resolving Mediators in Regulating and Conferring Macrophage Function.

Dalli J, Serhan CN.

Front Immunol. 2017 Nov 1;8:1400. doi: 10.3389/fimmu.2017.01400. eCollection 2017. Review.

22.

Immunoresolvents signaling molecules at intersection between the brain and immune system.

Dalli J, Serhan CN.

Curr Opin Immunol. 2018 Feb;50:48-54. doi: 10.1016/j.coi.2017.10.007. Epub 2017 Nov 16. Review.

23.

Atherosclerosis, Periodontal Disease, and Treatment with Resolvins.

Hamilton JA, Hasturk H, Kantarci A, Serhan CN, Van Dyke T.

Curr Atheroscler Rep. 2017 Nov 6;19(12):57. doi: 10.1007/s11883-017-0696-4. Review.

PMID:
29110146
24.

Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming.

Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J, Elliott H, Irimia D.

Nat Biomed Eng. 2017;1. pii: 0094. doi: 10.1038/s41551-017-0094. Epub 2017 Jun 30.

25.

ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance.

Sima C, Montero E, Nguyen D, Freire M, Norris P, Serhan CN, Van Dyke TE.

Sci Rep. 2017 Oct 9;7(1):12848. doi: 10.1038/s41598-017-13185-7. Erratum in: Sci Rep. 2018 Mar 2;8(1):4143.

26.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S.

J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.

PMID:
28986437
27.

Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways.

Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4530-4544. doi: 10.1167/iovs.17-21914.

28.

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration.

Serhan CN, Chiang N, Dalli J.

Mol Aspects Med. 2017 Sep 1. pii: S0098-2997(17)30091-2. doi: 10.1016/j.mam.2017.08.002. [Epub ahead of print] Review.

PMID:
28802833
29.

A cluster of immunoresolvents links coagulation to innate host defense in human blood.

Norris PC, Libreros S, Chiang N, Serhan CN.

Sci Signal. 2017 Aug 1;10(490). pii: eaan1471. doi: 10.1126/scisignal.aan1471.

30.

Specialized Proresolving Mediators Rescue Infant Mice from Lethal Citrobacter rodentium Infection and Promote Immunity against Reinfection.

Diaz LA, Altman NH, Khan W, Serhan CN, Adkins B.

Infect Immun. 2017 Sep 20;85(10). pii: e00464-17. doi: 10.1128/IAI.00464-17. Print 2017 Oct.

31.

The novel lipid mediator PD1n-3 DPA: An overview of the structural elucidation, synthesis, biosynthesis and bioactions.

Hansen TV, Dalli J, Serhan CN.

Prostaglandins Other Lipid Mediat. 2017 Nov;133:103-110. doi: 10.1016/j.prostaglandins.2017.06.003. Epub 2017 Jun 7. Review.

PMID:
28602942
32.

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection.

Gobbetti T, Dalli J, Colas RA, Federici Canova D, Aursnes M, Bonnet D, Alric L, Vergnolle N, Deraison C, Hansen TV, Serhan CN, Perretti M.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3963-3968. doi: 10.1073/pnas.1617290114. Epub 2017 Mar 29.

33.

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors.

Chiang N, Serhan CN.

Mol Aspects Med. 2017 Dec;58:114-129. doi: 10.1016/j.mam.2017.03.005. Epub 2017 Mar 31. Review.

PMID:
28336292
34.

Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology.

Serhan CN.

Mol Aspects Med. 2017 Dec;58:1-11. doi: 10.1016/j.mam.2017.03.001. Epub 2017 Mar 3. Review.

PMID:
28263773
35.

NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4 Synthesis.

Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon JS, Shinohara M, Hisata S, Howrylak JA, Suh GY, Ryter SW, Serhan CN, Choi AMK.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):713-726. doi: 10.1164/rccm.201604-0892OC.

PMID:
28245134
36.

Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics.

English JT, Norris PC, Hodges RR, Dartt DA, Serhan CN.

Prostaglandins Leukot Essent Fatty Acids. 2017 Feb;117:17-27. doi: 10.1016/j.plefa.2017.01.004. Epub 2017 Jan 19.

37.

Plasma lipoxin A4 and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas.

Fedirko V, McKeown-Eyssen G, Serhan CN, Barry EL, Sandler RS, Figueiredo JC, Ahnen DJ, Bresalier RS, Robertson DJ, Anderson CW, Baron JA.

Mol Carcinog. 2017 Aug;56(8):1977-1983. doi: 10.1002/mc.22629. Epub 2017 Mar 6.

38.

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms.

Serhan CN.

FASEB J. 2017 Apr;31(4):1273-1288. doi: 10.1096/fj.201601222R. Epub 2017 Jan 13. Review.

39.

Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution.

Dalli J, Colas RA, Arnardottir H, Serhan CN.

Immunity. 2017 Jan 17;46(1):92-105. doi: 10.1016/j.immuni.2016.12.009. Epub 2017 Jan 5.

40.

Fish Oil Supplementation in Pregnancy.

Ramaswami R, Serhan CN, Levy BD, Makrides M.

N Engl J Med. 2016 Dec 29;375(26):2599-2601. doi: 10.1056/NEJMclde1614333. No abstract available.

41.

Novel Resolvin D2 Receptor Axis in Infectious Inflammation.

Chiang N, de la Rosa X, Libreros S, Serhan CN.

J Immunol. 2017 Jan 15;198(2):842-851. doi: 10.4049/jimmunol.1601650. Epub 2016 Dec 19.

42.

Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes.

Freire MO, Dalli J, Serhan CN, Van Dyke TE.

J Immunol. 2017 Jan 15;198(2):718-728. doi: 10.4049/jimmunol.1601543. Epub 2016 Dec 19.

43.

Lipoxin A4 Counter-regulates Histamine-stimulated Glycoconjugate Secretion in Conjunctival Goblet Cells.

Hodges RR, Li D, Shatos MA, Serhan CN, Dartt DA.

Sci Rep. 2016 Nov 8;6:36124. doi: 10.1038/srep36124.

44.

Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation.

Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN.

J Immunol. 2016 Dec 1;197(11):4444-4452. Epub 2016 Oct 31.

45.

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages.

Dalli J, Vlasakov I, Riley IR, Rodriguez AR, Spur BW, Petasis NA, Chiang N, Serhan CN.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12232-12237. Epub 2016 Oct 6.

46.

Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins.

Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A.

J Nat Prod. 2016 Oct 28;79(10):2693-2702. Epub 2016 Oct 5.

47.

Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue.

Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Lopategi A, Dalli J, Lozano JJ, Arroyo V, Delgado S, Serhan CN, Clària J.

J Immunol. 2016 Oct 15;197(8):3360-3370. Epub 2016 Sep 19.

48.

Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes.

Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN, Baron RM.

Crit Care Med. 2017 Jan;45(1):58-68.

49.

Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses.

Chiurchiù V, Leuti A, Dalli J, Jacobsson A, Battistini L, Maccarrone M, Serhan CN.

Sci Transl Med. 2016 Aug 24;8(353):353ra111. doi: 10.1126/scitranslmed.aaf7483.

50.

Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation.

Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN.

J Immunol. 2016 Sep 15;197(6):2362-8. doi: 10.4049/jimmunol.1502268. Epub 2016 Aug 17.

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