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Items: 1 to 50 of 157

1.

Humanized mouse models reveal an immunologic classification of idiopathic CD4 lymphocytopenia subtypes.

Perez-Diez A, Liu X, Sheikh V, Roby G, Stroncek DF, Sereti I.

JCI Insight. 2019 Jul 25;4(14). pii: 127802. doi: 10.1172/jci.insight.127802. eCollection 2019 Jul 25.

2.

Corrigendum: Paradoxical CD4 Lymphopenia in Autoimmune Lymphoproliferative Syndrome (ALPS).

Lisco A, Wong CS, Price S, Ye P, Niemela J, Anderson M, Richards E, Manion M, Mystakelis H, Similuk M, Lo B, Stoddard J, Rosenzweig S, Vanpouille C, Rupert A, Maric I, Perez-Diez A, Parenti D, Burbelo PD, Rao VK, Sereti I.

Front Immunol. 2019 Jul 4;10:1552. doi: 10.3389/fimmu.2019.01552. eCollection 2019.

3.

Antiretroviral therapy administration in healthy rhesus macaques is associated with transient shifts in intestinal bacterial diversity and modest immunological perturbations.

Ortiz AM, Flynn JK, DiNapoli SR, Sortino O, Vujkovic-Cvijin I, Belkaid Y, Sereti I, Brenchley JM.

J Virol. 2019 Jul 3. pii: JVI.00472-19. doi: 10.1128/JVI.00472-19. [Epub ahead of print]

PMID:
31270225
4.

ART in HIV-Positive Persons With Low Pretreatment Viremia: Results From the START Trial.

Sereti I, Gulick RM, Krishnan S, Migueles SA, Palfreeman A, Touzeau-Römer V, Belloso WH, Emery S, Law MG; INSIGHT START Study Group.

J Acquir Immune Defic Syndr. 2019 Aug 1;81(4):456-462. doi: 10.1097/QAI.0000000000002052.

PMID:
31241541
5.

Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry.

Lage SL, Dominical VM, Wong CS, Sereti I.

Front Immunol. 2019 Jun 4;10:1284. doi: 10.3389/fimmu.2019.01284. eCollection 2019.

6.

A Phase I, Randomized, Controlled Clinical Study of CC-11050 in People Living With HIV With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE).

Boulougoura A, Gabriel E, Laidlaw E, Khetani V, Arakawa K, Higgins J, Rupert A, Gorelick RJ, Lumbard K, Pau A, Poole A, Kibiy A, Kumar P, Sereti I.

Open Forum Infect Dis. 2019 Jun 3;6(6):ofz246. doi: 10.1093/ofid/ofz246. eCollection 2019 Jun.

7.

Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario.

Narendran G, Oliveira-de-Souza D, Vinhaes CL, Akrami K, Fukutani KF, Banu K, Chandrasekaran P, Ravichandran N, Sereti I, Swaminathan S, Andrade BB.

BMC Infect Dis. 2019 Jun 17;19(1):529. doi: 10.1186/s12879-019-4182-1.

8.

Paradoxical CD4 Lymphopenia in Autoimmune Lymphoproliferative Syndrome (ALPS).

Lisco A, Wong CS, Price S, Ye P, Niemela J, Anderson M, Richards E, Manion M, Mystakelis H, Similuk M, Lo B, Stoddard J, Rosenzweig S, Vanpouille C, Rupert A, Maric I, Perez-Diez A, Parenti D, Burbelo PD, Rao VK, Sereti I.

Front Immunol. 2019 May 29;10:1193. doi: 10.3389/fimmu.2019.01193. eCollection 2019. Erratum in: Front Immunol. 2019 Jul 04;10:1552.

9.

IRIS as a post-transplantation complication in primary immunodeficiency with disseminated M. avium.

Manion M, Dimitrova D, Pei L, Gea-Banacloche J, Zelazny A, Lisco A, Zerbe C, Freeman AF, Holland SM, Kanakry CG, Kanakry JA, Sereti I.

Clin Infect Dis. 2019 Jun 12. pii: ciz507. doi: 10.1093/cid/ciz507. [Epub ahead of print]

PMID:
31190050
10.

Author Correction: Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome.

Silveira-Mattos PS, Narendran G, Akrami K, Fukutani KF, Anbalagan S, Nayak K, Subramanyam S, Subramani R, Vinhaes CL, Souza DO, Antonelli LR, Satagopan K, Porter BO, Sher A, Swaminathan S, Sereti I, Andrade BB.

Sci Rep. 2019 May 24;9(1):8036. doi: 10.1038/s41598-019-44429-3.

11.

Identification of rare HIV-1-infected patients with extreme CD4+ T cell decline despite ART-mediated viral suppression.

Lisco A, Wong CS, Lage SL, Levy I, Brophy J, Lennox J, Manion M, Anderson MV, Mejia Y, Grivas C, Mystakelis H, Burbelo PD, Perez-Diez A, Rupert A, Martens CA, Anzick SL, Morse C, Chan S, Deleage C, Sereti I.

JCI Insight. 2019 Apr 18;4(8). pii: 127113. doi: 10.1172/jci.insight.127113. eCollection 2019 Apr 18.

12.

Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome.

Silveira-Mattos PS, Narendran G, Akrami K, Fukutani KF, Anbalagan S, Nayak K, Subramanyam S, Subramani R, Vinhaes CL, Souza DO, Antonelli LR, Satagopan K, Porter BO, Sher A, Swaminathan S, Sereti I, Andrade BB.

Sci Rep. 2019 Feb 6;9(1):1502. doi: 10.1038/s41598-018-37846-3. Erratum in: Sci Rep. 2019 May 24;9(1):8036.

13.

The Effects of Recombinant Human Lactoferrin on Immune Activation and the Intestinal Microbiome Among Persons Living with Human Immunodeficiency Virus and Receiving Antiretroviral Therapy.

Sortino O, Hullsiek KH, Richards E, Rupert A, Schminke A, Tetekpor N, Quinones M, Prosser R, Schacker T, Sereti I, Baker JV.

J Infect Dis. 2019 May 24;219(12):1963-1968. doi: 10.1093/infdis/jiz042.

PMID:
30721997
14.

Emergence of Kaposi's Sarcoma Herpesvirus-Associated Complications Following Corticosteroid Use in TB-IRIS.

Manion M, Uldrick T, Polizzotto MN, Sheikh V, Roby G, Lurain K, Metzger D, Mican JM, Pau A, Lisco A, Laidlaw E, Hammoud DA, Whitby D, Yarchoan R, Sereti I.

Open Forum Infect Dis. 2018 Oct 12;5(10):ofy217. doi: 10.1093/ofid/ofy217. eCollection 2018 Oct.

15.

Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency.

Pastrana DV, Peretti A, Welch NL, Borgogna C, Olivero C, Badolato R, Notarangelo LD, Gariglio M, FitzGerald PC, McIntosh CE, Reeves J, Starrett GJ, Bliskovsky V, Velez D, Brownell I, Yarchoan R, Wyvill KM, Uldrick TS, Maldarelli F, Lisco A, Sereti I, Gonzalez CM, Androphy EJ, McBride AA, Van Doorslaer K, Garcia F, Dvoretzky I, Liu JS, Han J, Murphy PM, McDermott DH, Buck CB.

mSphere. 2018 Dec 12;3(6). pii: e00645-18. doi: 10.1128/mSphereDirect.00645-18.

16.

Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells.

Mudd JC, Busman-Sahay K, DiNapoli SR, Lai S, Sheik V, Lisco A, Deleage C, Richardson B, Palesch DJ, Paiardini M, Cameron M, Sereti I, Reeves RK, Estes JD, Brenchley JM.

Nat Commun. 2018 Sep 27;9(1):3967. doi: 10.1038/s41467-018-05528-3.

17.

Increased Metabolic Activity on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Human Immunodeficiency Virus-Associated Immune Reconstitution Inflammatory Syndrome.

Hammoud DA, Boulougoura A, Papadakis GZ, Wang J, Dodd LE, Rupert A, Higgins J, Roby G, Metzger D, Laidlaw E, Mican JM, Pau A, Lage S, Wong CS, Lisco A, Manion M, Sheikh V, Millo C, Sereti I.

Clin Infect Dis. 2019 Jan 7;68(2):229-238. doi: 10.1093/cid/ciy454.

PMID:
30215671
18.

Residual Immune Activation and Latency.

Bruzzesi E, Sereti I.

Curr Top Microbiol Immunol. 2018;417:157-180. doi: 10.1007/82_2018_118. Review.

PMID:
30105422
19.

IL-7 treatment supports CD8+ mucosa-associated invariant T-cell restoration in HIV-1-infected patients on antiretroviral therapy.

Sortino O, Richards E, Dias J, Leeansyah E, Sandberg JK, Sereti I.

AIDS. 2018 Mar 27;32(6):825-828. doi: 10.1097/QAD.0000000000001760.

PMID:
29543654
20.

Emergence of Polyfunctional Cytotoxic CD4+ T Cells in Mycobacterium avium Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Patients.

Hsu DC, Breglio KF, Pei L, Wong CS, Andrade BB, Sheikh V, Smelkinson M, Petrovas C, Rupert A, Gil-Santana L, Zelazny A, Holland SM, Olivier K, Barber D, Sereti I.

Clin Infect Dis. 2018 Jul 18;67(3):437-446. doi: 10.1093/cid/ciy016.

21.

Upbeat nystagmus in an HIV-positive patient with a tuberculoma in the medulla.

Coleman BW, Sereti I, Bishop R, Smith BR.

Lancet Infect Dis. 2018 Feb;18(2):225. doi: 10.1016/S1473-3099(17)30470-X. No abstract available.

PMID:
29412971
22.

IL-7 treatment supports CD8+ MAIT cell restoration in HIV-1 infected patients on ART.

Sortino O, Richards E, Dias J, Leeansyah E, Sandberg JK, Sereti I.

AIDS. 2018 Jan 23. doi: 10.1097/QAD.0000000000001760. [Epub ahead of print]

23.

Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments.

Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group .

Clin Infect Dis. 2018 May 2;66(10):1540-1549. doi: 10.1093/cid/cix1063.

24.

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy.

Wang C, Edilova MI, Wagar LE, Mujib S, Singer M, Bernard NF, Croughs T, Lederman MM, Sereti I, Fischl MA, Kremmer E, Ostrowski M, Routy JP, Watts TH.

J Immunol. 2018 Jan 15;200(2):558-564. doi: 10.4049/jimmunol.1601254. Epub 2017 Dec 8.

25.

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.

Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H.

Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 2.

26.

Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy.

Schechter ME, Andrade BB, He T, Richter GH, Tosh KW, Policicchio BB, Singh A, Raehtz KD, Sheikh V, Ma D, Brocca-Cofano E, Apetrei C, Tracy R, Ribeiro RM, Sher A, Francischetti IMB, Pandrea I, Sereti I.

Sci Transl Med. 2017 Aug 30;9(405). pii: eaam5441. doi: 10.1126/scitranslmed.aam5441.

27.

Choroid Plexitis and Ependymitis by Magnetic Resonance Imaging are Biomarkers of Neuronal Damage and Inflammation in HIV-negative Cryptococcal Meningoencephalitis.

Hammoud DA, Mahdi E, Panackal AA, Wakim P, Sheikh V, Sereti I, Bielakova B, Bennett JE, Williamson PR.

Sci Rep. 2017 Aug 23;7(1):9184. doi: 10.1038/s41598-017-09694-0.

28.

Immunologic Effects of Maraviroc in HIV-Infected Patients with Severe CD4 Lymphopenia Starting Antiretroviral Therapy: A Sub-Study of the CADIRIS Trial.

Belaunzarán-Zamudio PF, Azzoni L, Canaday DH, Caro-Vega YN, Clagett B, Rassool MS, Rodriguez B, Sanne I, Sereti I, Sierra-Madero JG, Lederman MM.

Pathog Immun. 2017;2(2):151-177. doi: 10.20411/pai.v2i2.181. Epub 2017 May 9.

29.

Susceptibility to Cryptococcal Meningoencephalitis Associated With Idiopathic CD4+ Lymphopenia and Secondary Germline or Acquired Defects.

Panackal AA, Rosen LB, Uzel G, Davis MJ, Hu G, Adeyemo A, Tekola-Ayele F, Lisco A, Diachok C, Kim JD, Shaw D, Sereti I, Stoddard J, Niemela J, Rosenzweig SD, Bennett JE, Williamson PR.

Open Forum Infect Dis. 2017 Jun 7;4(2):ofx082. doi: 10.1093/ofid/ofx082. eCollection 2017 Spring.

30.

Vitamin D deficiency is associated with IL-6 levels and monocyte activation in HIV-infected persons.

Manion M, Hullsiek KH, Wilson EMP, Rhame F, Kojic E, Gibson D, Hammer J, Patel P, Brooks JT, Baker JV, Sereti I; Study to Understand the Natural History of HIV/AIDS in the Era of Effective Antiretroviral Therapy (the ‘SUN Study’) Investigators.

PLoS One. 2017 May 2;12(5):e0175517. doi: 10.1371/journal.pone.0175517. eCollection 2017.

31.

Country of residence is associated with distinct inflammatory biomarker signatures in HIV-infected patients.

Manion M, Andrade BB, DerSimonian R, Gu W, Rupert A, Musselwhite LW, Sierra-Madero JG, Belaunzaran-Zamudio PF, Sanne I, Lederman MM, Sereti I.

J Virus Erad. 2017 Jan 1;3(1):24-33.

32.

Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection.

Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY.

JAMA Cardiol. 2017 Feb 1;2(2):163-171. doi: 10.1001/jamacardio.2016.4728.

33.

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study.

Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Peer CJ, Bevans M, Sereti I, Maldarelli F, Whitby D, Marshall V, Goncalves PH, Khetani V, Figg WD, Steinberg SM, Zeldis JB, Yarchoan R.

J Clin Oncol. 2016 Dec;34(34):4125-4131. Epub 2016 Oct 31. Erratum in: J Clin Oncol. 2018 Jul 1;36(19):2008.

34.
35.

Immune reconstitution inflammatory syndrome in HIV infection: taking the bad with the good.

Wong CS, Richards ES, Pei L, Sereti I.

Oral Dis. 2017 Oct;23(7):822-827. doi: 10.1111/odi.12606. Epub 2016 Dec 23. Review.

36.

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection.

Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS; RV254/SEARCH 010, RV304/SEARCH 013 and SEARCH 011 protocol teams.

Clin Infect Dis. 2017 Jan 15;64(2):124-131. doi: 10.1093/cid/ciw683. Epub 2016 Oct 12.

37.

Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation.

Crowell TA, Fletcher JL, Sereti I, Pinyakorn S, Dewar R, Krebs SJ, Chomchey N, Rerknimitr R, Schuetz A, Michael NL, Phanuphak N, Chomont N, Ananworanich J; RV254/SEARCH010 Study Group.

J Int AIDS Soc. 2016 Sep 15;19(1):21163. doi: 10.7448/IAS.19.1.21163. eCollection 2016.

38.

Impact of early cART in the gut during acute HIV infection.

Deleage C, Schuetz A, Alvord WG, Johnston L, Hao XP, Morcock DR, Rerknimitr R, Fletcher JL, Puttamaswin S, Phanuphak N, Dewar R, McCune JM, Sereti I, Robb M, Kim JH, Schacker TW, Hunt P, Lifson JD, Ananworanich J, Estes JD.

JCI Insight. 2016 Jul 7;1(10). pii: e87065.

39.

Transmitted HIV Drug Resistance Is High and Longstanding in Metropolitan Washington, DC.

Kassaye SG, Grossman Z, Balamane M, Johnston-White B, Liu C, Kumar P, Young M, Sneller MC, Sereti I, Dewar R, Rehm C, Meyer W 3rd, Shafer R, Katzenstein D, Maldarelli F.

Clin Infect Dis. 2016 Sep 15;63(6):836-843. doi: 10.1093/cid/ciw382. Epub 2016 Jun 15.

40.

Reply to Tham et al.

Xie YL, Chen RY, Sereti I, Zerbe CS, Holland SM, Browne SK.

Clin Infect Dis. 2016 Aug 15;63(4):573-4. doi: 10.1093/cid/ciw352. Epub 2016 May 25. No abstract available.

41.

Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy.

Hsu DC, Ma YF, Hur S, Li D, Rupert A, Scherzer R, Kalapus SC, Deeks S, Sereti I, Hsue PY.

AIDS. 2016 Aug 24;30(13):2065-74. doi: 10.1097/QAD.0000000000001149.

42.

Vitamin D, D-dimer, Interferon γ, and sCD14 Levels are Independently Associated with Immune Reconstitution Inflammatory Syndrome: A Prospective, International Study.

Musselwhite LW, Andrade BB, Ellenberg SS, Tierney A, Belaunzaran-Zamudio PF, Rupert A, Lederman MM, Sanne I, Sierra Madero JG, Sereti I.

EBioMedicine. 2016 Jan 14;4:115-23. doi: 10.1016/j.ebiom.2016.01.016. eCollection 2016 Feb.

43.

Serious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection.

Hsu DC, Sereti I.

Drugs. 2016 Apr;76(5):533-49. doi: 10.1007/s40265-016-0546-7. Review.

44.

Repeated Cycles of Recombinant Human Interleukin 7 in HIV-Infected Patients With Low CD4 T-Cell Reconstitution on Antiretroviral Therapy: Results of 2 Phase II Multicenter Studies.

Thiébaut R, Jarne A, Routy JP, Sereti I, Fischl M, Ive P, Speck RF, D'Offizi G, Casari S, Commenges D, Foulkes S, Natarajan V, Croughs T, Delfraissy JF, Tambussi G, Levy Y, Lederman MM.

Clin Infect Dis. 2016 May 1;62(9):1178-1185. doi: 10.1093/cid/ciw065. Epub 2016 Feb 7.

45.

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection.

Ananworanich J, Sacdalan CP, Pinyakorn S, Chomont N, de Souza M, Luekasemsuk T, Schuetz A, Krebs SJ, Dewar R, Jagodzinski L, Ubolyam S, Trichavaroj R, Tovanabutra S, Spudich S, Valcour V, Sereti I, Michael N, Robb M, Phanuphak P, Kim JH, Phanuphak N.

J Virus Erad. 2016;2:43-48.

46.

Towards a scalable HIV cure research agenda: the role of co-infections.

Sereti I, Folkers GK, Meintjes G, Boulware DR.

J Virus Erad. 2015;1(4):269-271. Epub 2015 Sep 24.

47.

Immune activation and HIV: an enduring relationship.

Sereti I, Altfeld M.

Curr Opin HIV AIDS. 2016 Mar;11(2):129-30. doi: 10.1097/COH.0000000000000244. No abstract available.

48.

Markers of HIV reservoir size and immune activation after treatment in acute HIV infection with and without raltegravir and maraviroc intensification.

Ananworanich J, Chomont N, Fletcher JL, Pinyakorn S, Schuetz A, Sereti I, Rerknimitr R, Dewar R, Kroon E, Vandergeeten C, Trichavaroj R, Chomchey N, Chalermchai T, Michael NL, Kim JH, Phanuphak P, Phanuphak N.

J Virus Erad. 2015;1(2):116-122. Epub 2015 Apr 1.

49.

HIV infection and immune activation: the role of coinfections.

Boulougoura A, Sereti I.

Curr Opin HIV AIDS. 2016 Mar;11(2):191-200. doi: 10.1097/COH.0000000000000241. Review.

50.

Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia.

Sheikh V, Porter BO, DerSimonian R, Kovacs SB, Thompson WL, Perez-Diez A, Freeman AF, Roby G, Mican J, Pau A, Rupert A, Adelsberger J, Higgins J, Bourgeois JS Jr, Jensen SM, Morcock DR, Burbelo PD, Osnos L, Maric I, Natarajan V, Croughs T, Yao MD, Estes JD, Sereti I.

Blood. 2016 Feb 25;127(8):977-88. doi: 10.1182/blood-2015-05-645077. Epub 2015 Dec 16.

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