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Items: 6

1.

The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer.

Harris RS, Serebrenik AA, Argyris P, Jarvis MC, Brown WL, Bazzaro M, Vogel RI, Erickson BK, Lee SH, Goergen KM, Maurer MJ, Oberg AL, Hou X, Weroha SJ, Kaufmann SH, Huang Y, Heinzen EP.

Clin Cancer Res. 2020 Feb 14. pii: clincanres.2786.2019. doi: 10.1158/1078-0432.CCR-19-2786. [Epub ahead of print]

PMID:
32060098
2.

HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators.

Salamango DJ, Ikeda T, Moghadasi SA, Wang J, McCann JL, Serebrenik AA, Ebrahimi D, Jarvis MC, Brown WL, Harris RS.

Cell Rep. 2019 Oct 29;29(5):1057-1065.e4. doi: 10.1016/j.celrep.2019.09.057.

3.

The deaminase APOBEC3B triggers the death of cells lacking uracil DNA glycosylase.

Serebrenik AA, Starrett GJ, Leenen S, Jarvis MC, Shaban NM, Salamango DJ, Nilsen H, Brown WL, Harris RS.

Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22158-22163. doi: 10.1073/pnas.1904024116. Epub 2019 Oct 14.

PMID:
31611371
4.

Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism.

Starrett GJ, Serebrenik AA, Roelofs PA, McCann JL, Verhalen B, Jarvis MC, Stewart TA, Law EK, Krupp A, Jiang M, Martens JWM, Cahir-McFarland E, Span PN, Harris RS.

mBio. 2019 Feb 5;10(1). pii: e02690-18. doi: 10.1128/mBio.02690-18.

5.

A panel of eGFP reporters for single base editing by APOBEC-Cas9 editosome complexes.

Martin AS, Salamango DJ, Serebrenik AA, Shaban NM, Brown WL, Harris RS.

Sci Rep. 2019 Jan 24;9(1):497. doi: 10.1038/s41598-018-36739-9.

6.

Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells.

Nikkilä J, Kumar R, Campbell J, Brandsma I, Pemberton HN, Wallberg F, Nagy K, Scheer I, Vertessy BG, Serebrenik AA, Monni V, Harris RS, Pettitt SJ, Ashworth A, Lord CJ.

Br J Cancer. 2017 Jun 27;117(1):113-123. doi: 10.1038/bjc.2017.133. Epub 2017 May 23.

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