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Items: 1 to 50 of 502

1.

Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids.

Serafini MM, Catanzaro M, Fagiani F, Simoni E, Caporaso R, Dacrema M, Romanoni I, Govoni S, Racchi M, Daglia M, Rosini M, Lanni C.

Front Pharmacol. 2020 Jan 28;10:1597. doi: 10.3389/fphar.2019.01597. eCollection 2019.

2.

Transcriptomics and Epigenomics in head and neck cancer: available repositories and molecular signatures.

Serafini MS, Lopez-Perez L, Fico G, Licitra L, De Cecco L, Resteghini C.

Cancers Head Neck. 2020 Jan 21;5:2. doi: 10.1186/s41199-020-0047-y. eCollection 2020. Review.

3.

Expanded circulating hematopoietic stem/progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis.

Capo V, Penna S, Merelli I, Barcella M, Scala S, Basso-Ricci L, Draghici E, Palagano E, Zonari E, Desantis G, Uva P, Cusano R, Sergi Sergi L, Crisafulli L, Moshous D, Stepensky P, Drabko K, Kaya Z, Unal E, Gezdirici A, Menna G, Serafini M, Aiuti A, Locatelli SL, Carlo-Stella C, Schulz AS, Ficara F, Sobacchi C, Gentner B, Villa A.

Haematologica. 2020 Jan 16. pii: haematol.2019.238261. doi: 10.3324/haematol.2019.238261. [Epub ahead of print]

4.

Nor-Lignans: Occurrence in Plants and Biological Activities-A Review.

Frezza C, Venditti A, Toniolo C, De Vita D, Franceschin M, Ventrone A, Tomassini L, Foddai S, Guiso M, Nicoletti M, Serafini M, Bianco A.

Molecules. 2020 Jan 3;25(1). pii: E197. doi: 10.3390/molecules25010197. Review.

5.

Preliminary in Vitro Assessment of the Potential of EST64454, a Sigma-1 Receptor Antagonist, for Pharmacokinetic Drug-Drug Interactions.

Yeste S, Reinoso RF, Ayet E, Pretel MJ, Balada A, Serafini MT.

Biol Pharm Bull. 2020;43(1):68-76. doi: 10.1248/bpb.b19-00542.

6.

Editorial: Immunonutrient Supplementation.

Magrone T, Haslberger A, Jirillo E, Serafini M.

Front Nutr. 2019 Dec 3;6:182. doi: 10.3389/fnut.2019.00182. eCollection 2019. No abstract available.

7.

4-Aryl-1-oxa-4,9-diazaspiro[5.5]undecane Derivatives as Dual μ-Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain.

García M, Virgili M, Alonso M, Alegret C, Fernández B, Port A, Pascual R, Monroy X, Vidal-Torres A, Serafini MT, Vela JM, Almansa C.

J Med Chem. 2019 Dec 5. doi: 10.1021/acs.jmedchem.9b01256. [Epub ahead of print]

PMID:
31743642
8.

The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels.

Zhou Y, Cai S, Moutal A, Yu J, Gómez K, Madura CL, Shan Z, Pham NYN, Serafini MJ, Dorame A, Scott DD, François-Moutal L, Perez-Miller S, Patek M, Khanna M, Khanna R.

ACS Chem Neurosci. 2019 Dec 18;10(12):4834-4846. doi: 10.1021/acschemneuro.9b00547. Epub 2019 Nov 21.

PMID:
31697467
9.

Eplingiella fruticosa (Lamiaceae) essential oil complexed with β-cyclodextrin improves its anti-hyperalgesic effect in a chronic widespread non-inflammatory muscle pain animal model.

John de Oliveira Melo A, Heimarth L, Maria Dos Santos Carvalho A, de Souza Siqueira Quintans J, Serafini MR, Antunes de Souza Araújo A, Alves PB, Ribeiro AM, Shanmugam S, Quintans-Júnior LJ, Duarte MC.

Food Chem Toxicol. 2020 Jan;135:110940. doi: 10.1016/j.fct.2019.110940. Epub 2019 Nov 3.

PMID:
31693914
10.

Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role.

Giatti S, Diviccaro S, Serafini MM, Caruso D, Garcia-Segura LM, Viviani B, Melcangi RC.

Front Neuroendocrinol. 2020 Jan;56:100804. doi: 10.1016/j.yfrne.2019.100804. Epub 2019 Nov 2. Review.

PMID:
31689419
11.

The Patenting and Technological Trends in Candidiasis Treatment: A Systematic Review (2014-2018).

Alves IA, Savi FM, de Vasconcelos C Braz J, Quintans Junior LJ, Serafini MR.

Curr Top Med Chem. 2019;19(28):2629-2639. doi: 10.2174/1568026619666191030091211.

PMID:
31670621
12.

Protective effects of flavonoid composition rich P. subpeltata Ortega. on indomethacin induced experimental ulcerative colitis in rat models of inflammatory bowel diseases.

Shanmugam S, Thangaraj P, Dos Santos Lima B, Trindade GGG, Narain N, Mara de Oliveira E Silva A, Santin JR, Broering MF, Serafini MR, Quintans-Júnior LJ, Antunes de Souza Araújo A.

J Ethnopharmacol. 2020 Feb 10;248:112350. doi: 10.1016/j.jep.2019.112350. Epub 2019 Oct 24.

PMID:
31669103
13.

Corrigendum: Metabolic Food Waste and Ecological Impact of Obesity in FAO World's Region.

Toti E, Di Mattia C, Serafini M.

Front Nutr. 2019 Oct 11;6:160. doi: 10.3389/fnut.2019.00160. eCollection 2019.

14.

A primer of deuterium in drug design.

Cargnin S, Serafini M, Pirali T.

Future Med Chem. 2019 Aug;11(16):2039-2042. doi: 10.4155/fmc-2019-0183. No abstract available.

15.

Metabolic Food Waste and Ecological Impact of Obesity in FAO World's Region.

Toti E, Di Mattia C, Serafini M.

Front Nutr. 2019 Aug 23;6:126. doi: 10.3389/fnut.2019.00126. eCollection 2019. Erratum in: Front Nutr. 2019 Oct 11;6:160.

16.

Higher Dietary Non-enzymatic Antioxidant Capacity Is Associated with Decreased Risk of All-Cause and Cardiovascular Disease Mortality in Japanese Adults.

Kashino I, Mizoue T, Serafini M, Akter S, Sawada N, Ishihara J, Kotemori A, Inoue M, Yamaji T, Goto A, Iwasaki M, Noda M, Tsugane S; Japan Public Health Center-based Prospective Study Group.

J Nutr. 2019 Sep 9. pii: nxz145. doi: 10.1093/jn/nxz145. [Epub ahead of print]

PMID:
31498407
17.

Soft drugs for dermatological applications: recent trends.

Aprile S, Serafini M, Pirali T.

Drug Discov Today. 2019 Dec;24(12):2234-2246. doi: 10.1016/j.drudis.2019.08.007. Epub 2019 Sep 5. Review.

PMID:
31494188
18.

Pedicularis L. Genus: Systematics, Botany, Phytochemistry, Chemotaxonomy, Ethnopharmacology, and Other.

Frezza C, Venditti A, Toniolo C, Vita D, Serafini I, Ciccòla A, Franceschin M, Ventrone A, Tomassini L, Foddai S, Guiso M, Nicoletti M, Bianco A, Serafini M.

Plants (Basel). 2019 Aug 27;8(9). pii: E306. doi: 10.3390/plants8090306. Review.

19.

Antioxidant Activities in vitro of Water and Liposoluble Extracts Obtained by Different Species of Edible Insects and Invertebrates.

Di Mattia C, Battista N, Sacchetti G, Serafini M.

Front Nutr. 2019 Jul 15;6:106. doi: 10.3389/fnut.2019.00106. eCollection 2019.

20.

Mining of Self-Organizing Map Gene-Expression Portraits Reveals Prognostic Stratification of HPV-Positive Head and Neck Squamous Cell Carcinoma.

Locati LD, Serafini MS, Iannò MF, Carenzo A, Orlandi E, Resteghin C, Cavalieri S, Bossi P, Canevari S, Licitra L, De Cecco L.

Cancers (Basel). 2019 Jul 26;11(8). pii: E1057. doi: 10.3390/cancers11081057.

21.

Hepatitis E should be considered a neglected tropical disease.

Azman AS, Ciglenecki I, Wamala JF, Lynch J, Aggarwal R, Rahman M, Wong S, Serafini M, Moussa AM, Dalton HR, Shrestha A, Pant R, Peck R, Gurley ES.

PLoS Negl Trop Dis. 2019 Jul 25;13(7):e0007453. doi: 10.1371/journal.pntd.0007453. eCollection 2019 Jul. No abstract available.

22.

Phytomedicines containing Matricaria species for the treatment of skin diseases: A biotechnological approach.

Dos Santos DS, Barreto RSS, Serafini MR, Gouveia DN, Marques RS, Nascimento LC, Nascimento JC, Guimarães AG.

Fitoterapia. 2019 Oct;138:104267. doi: 10.1016/j.fitote.2019.104267. Epub 2019 Jul 15. Review.

PMID:
31319107
23.

Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation.

Dufrusine B, Di Francesco A, Oddi S, Scipioni L, Angelucci CB, D'Addario C, Serafini M, Häfner AK, Steinhilber D, Maccarrone M, Dainese E.

Front Immunol. 2019 Jun 28;10:1347. doi: 10.3389/fimmu.2019.01347. eCollection 2019.

24.

Relationship between dietary non-enzymatic antioxidant capacity and type 2 diabetes risk in the Japan Public Health Center-based Prospective Study.

Kashino I, Serafini M, Kurotani K, Akter S, Mizoue T, Ishihara J, Kotemori A, Sawada N, Inoue M, Iwasaki M, Noda M, Tsugane S; Japan Public Health Center-based Prospective Study Group.

Nutrition. 2019 Oct;66:62-69. doi: 10.1016/j.nut.2019.03.011. Epub 2019 Mar 29.

PMID:
31212252
25.

Diagnostic Value of Histological Analysis of Punch Biopsies in Suspected Cutaneous Buruli Ulcer: A Study on 32 Cases of Confirmed Buruli Ulcer in Cameroon.

Ibrahim YL, Masouyé I, Tschanz E, Atangana P, Etard JF, Serafini M, Mueller YK, Toutous Trellu L.

Dermatopathology (Basel). 2019 May 7;6(2):28-36. doi: 10.1159/000498969. eCollection 2019 Apr-Jun.

26.

Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors.

Serafini M, Torre E, Aprile S, Massarotti A, Fallarini S, Pirali T.

Molecules. 2019 May 15;24(10). pii: E1874. doi: 10.3390/molecules24101874.

27.

Acute myeloid leukaemia niche regulates response to L-asparaginase.

Michelozzi IM, Granata V, De Ponti G, Alberti G, Tomasoni C, Antolini L, Gambacorti-Passerini C, Gentner B, Dazzi F, Biondi A, Coliva T, Rizzari C, Pievani A, Serafini M.

Br J Haematol. 2019 Aug;186(3):420-430. doi: 10.1111/bjh.15920. Epub 2019 May 1.

PMID:
31044436
28.

Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.

Pirali T, Galli U, Serafini M, Griglio A, Genazzani AA, Tron GC.

Methods Mol Biol. 2019;1987:207-221. doi: 10.1007/978-1-4939-9446-5_13.

PMID:
31028682
29.

Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels.

Shan Z, Cai S, Yu J, Zhang Z, Vallecillo TGM, Serafini MJ, Thomas AM, Pham NYN, Bellampalli SS, Moutal A, Zhou Y, Xu GB, Xu YM, Luo S, Patek M, Streicher JM, Gunatilaka AAL, Khanna R.

ACS Chem Neurosci. 2019 Jun 19;10(6):2939-2955. doi: 10.1021/acschemneuro.9b00166. Epub 2019 Apr 18.

PMID:
30946560
30.

Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.

Khanna R, Yu J, Yang X, Moutal A, Chefdeville A, Gokhale V, Shuja Z, Chew LA, Bellampalli SS, Luo S, François-Moutal L, Serafini MJ, Ha T, Perez-Miller S, Park KD, Patwardhan AM, Streicher JM, Colecraft HM, Khanna M.

Pain. 2019 Jul;160(7):1644-1661. doi: 10.1097/j.pain.0000000000001524.

PMID:
30933958
31.

A functional gene expression analysis in epithelial sinonasal cancer: Biology and clinical relevance behind three histological subtypes.

De Cecco L, Serafini MS, Facco C, Granata R, Orlandi E, Fallai C, Licitra L, Marchesi E, Perrone F, Pilotti S, Quattrone P, Piazza C, Sessa F, Turri-Zanoni M, Battaglia P, Castelnuovo P, Antognoni P, Canevari S, Bossi P.

Oral Oncol. 2019 Mar;90:94-101. doi: 10.1016/j.oraloncology.2019.02.003. Epub 2019 Feb 11.

32.

Hematopoietic Stem Cell Transplantation for Mucopolysaccharidoses: Past, Present, and Future.

Taylor M, Khan S, Stapleton M, Wang J, Chen J, Wynn R, Yabe H, Chinen Y, Boelens JJ, Mason RW, Kubaski F, Horovitz DDG, Barth AL, Serafini M, Bernardo ME, Kobayashi H, Orii KE, Suzuki Y, Orii T, Tomatsu S.

Biol Blood Marrow Transplant. 2019 Jul;25(7):e226-e246. doi: 10.1016/j.bbmt.2019.02.012. Epub 2019 Feb 14. Review.

PMID:
30772512
33.

Advances of nanosystems containing cyclodextrins and their applications in pharmaceuticals.

Menezes PDP, Andrade TA, Frank LA, de Souza EPBSS, Trindade GDGG, Trindade IAS, Serafini MR, Guterres SS, Araújo AAS.

Int J Pharm. 2019 Mar 25;559:312-328. doi: 10.1016/j.ijpharm.2019.01.041. Epub 2019 Jan 29. Review.

PMID:
30703500
34.

Applications of Deuterium in Medicinal Chemistry.

Pirali T, Serafini M, Cargnin S, Genazzani AA.

J Med Chem. 2019 Jun 13;62(11):5276-5297. doi: 10.1021/acs.jmedchem.8b01808. Epub 2019 Jan 25.

PMID:
30640460
35.

Tacking the vector of Xylella fastidiosa: geo-statistical analysis of long-term field observations on host plants influencing the distribution of Phylaenus spumarius nymphs.

Latini A, Foxi C, Borfecchia F, Lentini A, De Cecco L, Iantosca D, Serafini M, Laneri U, Citterio M, Campiotti A, Benelli G, Mariani S.

Environ Sci Pollut Res Int. 2019 Mar;26(7):6503-6516. doi: 10.1007/s11356-018-3870-5. Epub 2019 Jan 9.

PMID:
30627995
36.

A new byciclic monoterpene glucoside and a new biflavone from the male reproduction organs of Wollemia nobilis.

Venditti A, Frezza C, Rossi G, Serafini I, Ciccòla A, Sciubba F, Foddai S, Tomassini L, Bianco A, Serafini M.

Fitoterapia. 2019 Mar;133:62-69. doi: 10.1016/j.fitote.2018.12.012. Epub 2018 Dec 17.

PMID:
30572087
37.

Bioactive factors secreted from mesenchymal stromal cells protect the intestines from experimental colitis in a three-dimensional culture.

DA Costa Gonçalves F, Serafini MA, Mello HF, Pfaffenseller B, Araújo AB, Visioli F, Paz AH.

Cytotherapy. 2018 Dec;20(12):1459-1471. doi: 10.1016/j.jcyt.2018.06.007. Epub 2018 Oct 27.

PMID:
30523788
38.

A syn-ent-labdadiene derivative with a rare spiro-β-lactone function from the male cones of Wollemia nobilis.

Venditti A, Frezza C, Vincenti F, Brodella A, Sciubba F, Montesano C, Franceschin M, Sergi M, Foddai S, Di Cocco ME, Curini R, Delfini M, Bianco A, Serafini M.

Phytochemistry. 2019 Feb;158:91-95. doi: 10.1016/j.phytochem.2018.11.012. Epub 2018 Nov 24.

PMID:
30481664
39.

Arynes and isocyanides: Two close-knit partners in multicomponent reactions.

Serafini M, Pirali T.

Drug Discov Today Technol. 2018 Nov;29:35-41. doi: 10.1016/j.ddtec.2018.06.007. Epub 2018 Jul 2. Review.

PMID:
30471672
40.

Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches.

Fraldi A, Serafini M, Sorrentino NC, Gentner B, Aiuti A, Bernardo ME.

Ital J Pediatr. 2018 Nov 16;44(Suppl 2):130. doi: 10.1186/s13052-018-0565-y. Review.

41.

Wolf predation on wild ungulates: how slope and habitat cover influence the localization of kill sites.

Torretta E, Caviglia L, Serafini M, Meriggi A.

Curr Zool. 2018 Jun;64(3):271-275. doi: 10.1093/cz/zox031. Epub 2017 May 8.

42.

Effects of High Consumption of Vegetables on Clinical, Immunological, and Antioxidant Markers in Subjects at Risk of Cardiovascular Diseases.

Peluso I, Raguzzini A, Catasta G, Cammisotto V, Perrone A, Tomino C, Toti E, Serafini M.

Oxid Med Cell Longev. 2018 Oct 8;2018:5417165. doi: 10.1155/2018/5417165. eCollection 2018.

43.

Dietary non-enzymatic antioxidant capacity and the risk of myocardial infarction: the Swedish National March Cohort.

Hantikainen E, Grotta A, Serafini M, Trolle Lagerros Y, Nyren O, Ye W, Colarusso L, Bellocco R.

Int J Epidemiol. 2018 Dec 1;47(6):1947-1955. doi: 10.1093/ije/dyy220.

PMID:
30351384
44.

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.

Riva B, Griglio A, Serafini M, Cordero-Sanchez C, Aprile S, Di Paola R, Gugliandolo E, Alansary D, Biocotino I, Lim D, Grosa G, Galli U, Niemeyer B, Sorba G, Canonico PL, Cuzzocrea S, Genazzani AA, Pirali T.

J Med Chem. 2018 Nov 8;61(21):9756-9783. doi: 10.1021/acs.jmedchem.8b01512. Epub 2018 Oct 30.

PMID:
30347159
45.

Molecular mechanism underlying orofacial antinociceptive activity of Vanillosmopsis arborea Baker (Asteraceae) essential oil complexed with β-cyclodextrin.

Leite LHI, Leite GO, da Silva BAF, Santos SAAR, Magalhães FEA, Menezes PP, Serafini MR, Teixeira CS, Brito RG, Santos PL, da Costa JGM, Araújo AAS, Quintans-Júnior LJ, de Menezes IRA, Coutinho HDM, Campos AR.

Phytomedicine. 2019 Mar 1;55:293-301. doi: 10.1016/j.phymed.2018.09.173. Epub 2018 Sep 17.

PMID:
30293859
46.

Progress and Challenges in Using Oral Cholera Vaccines to Control Outbreaks: The Médecins Sans Frontières Experience.

Ciglenecki I, Azman AS, Jamet C, Serafini M, Luquero FJ, Cabrol JC.

J Infect Dis. 2018 Oct 15;218(suppl_3):S165-S166. doi: 10.1093/infdis/jiy487.

47.

A new high-throughput method to make a quality control on tattoo inks.

Persechino S, Toniolo C, Ciccola A, Serafini I, Tammaro A, Postorino P, Persechino F, Serafini M.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 5;206:547-551. doi: 10.1016/j.saa.2018.08.037. Epub 2018 Aug 21.

PMID:
30179798
48.

Unexpected Echinococcus multilocularis infections in shepherd dogs and wolves in south-western Italian Alps: A new endemic area?

Massolo A, Valli D, Wassermann M, Cavallero S, D'Amelio S, Meriggi A, Torretta E, Serafini M, Casulli A, Zambon L, Boni CB, Ori M, Romig T, Macchioni F.

Int J Parasitol Parasites Wildl. 2018 Aug 13;7(3):309-316. doi: 10.1016/j.ijppaw.2018.08.001. eCollection 2018 Dec.

49.

Phytochemical profile of Euphorbia peplus L. collected in Central Italy and NMR semi-quantitative analysis of the diterpenoid fraction.

Frezza C, Venditti A, Sciubba F, Tomai P, Antonetti M, Franceschin M, Di Cocco ME, Gentili A, Delfini M, Serafini M, Bianco A.

J Pharm Biomed Anal. 2018 Oct 25;160:152-159. doi: 10.1016/j.jpba.2018.07.059. Epub 2018 Jul 31.

PMID:
30086508
50.

An integrated strategy to correlate aggregation state, structure and toxicity of Aß 1-42 oligomers.

Bisceglia F, Natalello A, Serafini MM, Colombo R, Verga L, Lanni C, De Lorenzi E.

Talanta. 2018 Oct 1;188:17-26. doi: 10.1016/j.talanta.2018.05.062. Epub 2018 May 18.

PMID:
30029360

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