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Items: 17

1.

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity.

Pereira SP, Deus CM, Serafim TL, Cunha-Oliveira T, Oliveira PJ.

Toxicol Sci. 2018 Jul 1;164(1):191-204. doi: 10.1093/toxsci/kfy068.

PMID:
29945227
2.

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative.

Teixeira J, Amorim R, Santos K, Soares P, Datta S, Cortopassi GA, Serafim TL, Sardão VA, Garrido J, Borges F, Oliveira PJ.

Toxicology. 2018 Jan 15;393:123-139. doi: 10.1016/j.tox.2017.11.014. Epub 2017 Nov 12.

PMID:
29141199
3.

Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts.

Coelho AR, Martins TR, Couto R, Deus C, Pereira CV, Simões RF, Rizvanov AA, Silva F, Cunha-Oliveira T, Oliveira PJ, Serafim TL.

Biochim Biophys Acta. 2017 Nov;1863(11):2904-2923. doi: 10.1016/j.bbadis.2017.07.030. Epub 2017 Jul 29.

PMID:
28760703
4.

From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia.

Oliveira ML, Akkapeddi P, Alcobia I, Almeida AR, Cardoso BA, Fragoso R, Serafim TL, Barata JT.

Cell Signal. 2017 Oct;38:10-25. doi: 10.1016/j.cellsig.2017.06.011. Epub 2017 Jun 21. Review.

5.

Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells.

Deus CM, Serafim TL, Magalhães-Novais S, Vilaça A, Moreira AC, Sardão VA, Cardoso SM, Oliveira PJ.

Arch Toxicol. 2017 Mar;91(3):1261-1278. doi: 10.1007/s00204-016-1784-x. Epub 2016 Jun 29.

PMID:
27358235
6.

Cardiomyocyte H9c2 cells present a valuable alternative to fish lethal testing for azoxystrobin.

Rodrigues ET, Pardal MÂ, Laizé V, Cancela ML, Oliveira PJ, Serafim TL.

Environ Pollut. 2015 Nov;206:619-26. doi: 10.1016/j.envpol.2015.08.026. Epub 2015 Aug 27.

PMID:
26319055
7.

Role of mtDNA-related mitoepigenetic phenomena in cancer.

Ferreira A, Serafim TL, Sardão VA, Cunha-Oliveira T.

Eur J Clin Invest. 2015 Jan;45 Suppl 1:44-9. doi: 10.1111/eci.12359. Review.

PMID:
25524586
8.

Targeting mitochondrial function for the treatment of breast cancer.

Deus CM, Coelho AR, Serafim TL, Oliveira PJ.

Future Med Chem. 2014 Sep;6(13):1499-513. doi: 10.4155/fmc.14.100. Review.

PMID:
25365234
9.

Analysis of pro-apoptotic protein trafficking to and from mitochondria.

Vega-Naredo I, Cunha-Oliveira T, Serafim TL, Sardao VA, Oliveira PJ.

Methods Mol Biol. 2015;1241:163-80. doi: 10.1007/978-1-4939-1875-1_14.

PMID:
25308496
10.

New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death.

Serafim TL, Carvalho FS, Bernardo TC, Pereira GC, Perkins E, Holy J, Krasutsky DA, Kolomitsyna ON, Krasutsky PA, Oliveira PJ.

Bioorg Med Chem. 2014 Nov 1;22(21):6270-87. doi: 10.1016/j.bmc.2014.08.013. Epub 2014 Sep 6.

PMID:
25245673
11.

Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition.

Bernardo TC, Cunha-Oliveira T, Serafim TL, Holy J, Krasutsky D, Kolomitsyna O, Krasutsky P, Moreno AM, Oliveira PJ.

Bioorg Med Chem. 2013 Dec 1;21(23):7239-49. doi: 10.1016/j.bmc.2013.09.066. Epub 2013 Oct 8.

PMID:
24156937
12.

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells.

Serafim TL, Carvalho FS, Marques MP, Calheiros R, Silva T, Garrido J, Milhazes N, Borges F, Roleira F, Silva ET, Holy J, Oliveira PJ.

Chem Res Toxicol. 2011 May 16;24(5):763-74. doi: 10.1021/tx200126r. Epub 2011 Apr 28.

PMID:
21504213
13.

Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?

Diogo CV, Machado NG, Barbosa IA, Serafim TL, Burgeiro A, Oliveira PJ.

Curr Drug Targets. 2011 Jun;12(6):850-9. Review.

PMID:
21269266
14.

Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells--nuclear vs. mitochondrial effects.

Serafim TL, Matos JA, Sardão VA, Pereira GC, Branco AF, Pereira SL, Parke D, Perkins EL, Moreno AJ, Holy J, Oliveira PJ.

Biochem Pharmacol. 2008 Dec 1;76(11):1459-75. doi: 10.1016/j.bcp.2008.07.013. Epub 2008 Jul 19.

PMID:
18692024
15.

Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions.

Pereira GC, Branco AF, Matos JA, Pereira SL, Parke D, Perkins EL, Serafim TL, Sardão VA, Santos MS, Moreno AJ, Holy J, Oliveira PJ.

J Pharmacol Exp Ther. 2007 Nov;323(2):636-49. Epub 2007 Aug 17.

16.

Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line.

Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J.

Cancer Chemother Pharmacol. 2008 May;61(6):1007-18. Epub 2007 Jul 28.

PMID:
17661039
17.

Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations -- Relevance for carbaryl toxicity mechanisms.

Moreno AJ, Serafim TL, Oliveira PJ, Madeira VM.

Chemosphere. 2007 Jan;66(3):404-11. Epub 2006 Jul 24.

PMID:
16860847

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