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Items: 1 to 50 of 292

1.

Quantitative evidence for early metastatic seeding in colorectal cancer.

Hu Z, Ding J, Ma Z, Sun R, Seoane JA, Scott Shaffer J, Suarez CJ, Berghoff AS, Cremolini C, Falcone A, Loupakis F, Birner P, Preusser M, Lenz HJ, Curtis C.

Nat Genet. 2019 Jul;51(7):1113-1122. doi: 10.1038/s41588-019-0423-x. Epub 2019 Jun 17.

PMID:
31209394
2.

LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.

Pascual-García M, Bonfill-Teixidor E, Planas-Rigol E, Rubio-Perez C, Iurlaro R, Arias A, Cuartas I, Sala-Hojman A, Escudero L, Martínez-Ricarte F, Huber-Ruano I, Nuciforo P, Pedrosa L, Marques C, Braña I, Garralda E, Vieito M, Squatrito M, Pineda E, Graus F, Espejo C, Sahuquillo J, Tabernero J, Seoane J.

Nat Commun. 2019 Jun 11;10(1):2416. doi: 10.1038/s41467-019-10369-9.

3.

The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer.

De Mattos-Arruda L, Sammut SJ, Ross EM, Bashford-Rogers R, Greenstein E, Markus H, Morganella S, Teng Y, Maruvka Y, Pereira B, Rueda OM, Chin SF, Contente-Cuomo T, Mayor R, Arias A, Ali HR, Cope W, Tiezzi D, Dariush A, Dias Amarante T, Reshef D, Ciriaco N, Martinez-Saez E, Peg V, Ramon Y Cajal S, Cortes J, Vassiliou G, Getz G, Nik-Zainal S, Murtaza M, Friedman N, Markowetz F, Seoane J, Caldas C.

Cell Rep. 2019 May 28;27(9):2690-2708.e10. doi: 10.1016/j.celrep.2019.04.098.

4.

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

Rueda OM, Sammut SJ, Seoane JA, Chin SF, Caswell-Jin JL, Callari M, Batra R, Pereira B, Bruna A, Ali HR, Provenzano E, Liu B, Parisien M, Gillett C, McKinney S, Green AR, Murphy L, Purushotham A, Ellis IO, Pharoah PD, Rueda C, Aparicio S, Caldas C, Curtis C.

Nature. 2019 Mar;567(7748):399-404. doi: 10.1038/s41586-019-1007-8. Epub 2019 Mar 13.

PMID:
30867590
5.

Responses of seed size, ant worker size, and seed removal rate to elevation in Mediterranean grasslands.

Silvestre M, Aguilar A, Seoane J, Azcárate FM.

Oecologia. 2019 Mar;189(3):781-793. doi: 10.1007/s00442-019-04356-6. Epub 2019 Feb 24.

PMID:
30799515
6.

Exploring the association between initial serum alcohol concentration and polysubstance use: More than a simple "gateway drug" effect?

Jordan A, Salen P, Wojda TR, Cohen MS, Hasani A, Luster J, Seoane J, Stawicki SP, Stankewicz H.

Int J Crit Illn Inj Sci. 2018 Oct-Dec;8(4):201-206. doi: 10.4103/IJCIIS.IJCIIS_65_18.

7.

Cerebrospinal fluid cell-free tumour DNA as a liquid biopsy for primary brain tumours and central nervous system metastases.

Seoane J, De Mattos-Arruda L, Le Rhun E, Bardelli A, Weller M.

Ann Oncol. 2019 Feb 1;30(2):211-218. doi: 10.1093/annonc/mdy544.

PMID:
30576421
8.

Spatial patterns of species richness and nestedness in ant assemblages along an elevational gradient in a Mediterranean mountain range.

Flores O, Seoane J, Hevia V, Azcárate FM.

PLoS One. 2018 Dec 19;13(12):e0204787. doi: 10.1371/journal.pone.0204787. eCollection 2018.

9.

Assessment of ERBB2/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines.

Press MF, Seoane JA, Curtis C, Quinaux E, Guzman R, Sauter G, Eiermann W, Mackey JR, Robert N, Pienkowski T, Crown J, Martin M, Valero V, Bee V, Ma Y, Villalobos I, Slamon DJ.

JAMA Oncol. 2019 Mar 1;5(3):366-375. doi: 10.1001/jamaoncol.2018.6012.

10.

The chromatin accessibility landscape of primary human cancers.

Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, Felau I, Castro MAA, Berman BP, Staudt LM, Zenklusen JC, Laird PW, Curtis C; Cancer Genome Atlas Analysis Network, Greenleaf WJ, Chang HY.

Science. 2018 Oct 26;362(6413). pii: eaav1898. doi: 10.1126/science.aav1898.

11.

p95HER2-T cell bispecific antibody for breast cancer treatment.

Rius Ruiz I, Vicario R, Morancho B, Morales CB, Arenas EJ, Herter S, Freimoser-Grundschober A, Somandin J, Sam J, Ast O, Barriocanal ÁM, Luque A, Escorihuela M, Varela I, Cuartas I, Nuciforo P, Fasani R, Peg V, Rubio I, Cortés J, Serra V, Escriva-de-Romani S, Sperinde J, Chenna A, Huang W, Winslow J, Albanell J, Seoane J, Scaltriti M, Baselga J, Tabernero J, Umana P, Bacac M, Saura C, Klein C, Arribas J.

Sci Transl Med. 2018 Oct 3;10(461). pii: eaat1445. doi: 10.1126/scitranslmed.aat1445.

PMID:
30282693
12.

Subjugation of TGFβ Signaling by Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma Shifts DNA Repair from Homologous Recombination to Alternative End Joining.

Liu Q, Ma L, Jones T, Palomero L, Pujana MA, Martinez-Ruiz H, Ha PK, Murnane J, Cuartas I, Seoane J, Baumann M, Linge A, Barcellos-Hoff MH.

Clin Cancer Res. 2018 Dec 1;24(23):6001-6014. doi: 10.1158/1078-0432.CCR-18-1346. Epub 2018 Aug 7.

PMID:
30087144
13.

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence.

Puig I, Tenbaum SP, Chicote I, Arqués O, Martínez-Quintanilla J, Cuesta-Borrás E, Ramírez L, Gonzalo P, Soto A, Aguilar S, Eguizabal C, Caratù G, Prat A, Argilés G, Landolfi S, Casanovas O, Serra V, Villanueva A, Arroyo AG, Terracciano L, Nuciforo P, Seoane J, Recio JA, Vivancos A, Dienstmann R, Tabernero J, Palmer HG.

J Clin Invest. 2018 Aug 31;128(9):3887-3905. doi: 10.1172/JCI96393. Epub 2018 Aug 6.

14.

Comments to Angulo et al. 2016 on "Sea-level fluctuations and coastal evolution in the state of Rio de Janeiro, southeastern - Brazil" by Castro et al. 2014.

Castro JWA, Seoane JCS, Cunha AMD, Malta JV, Oliveira CA, Vaz SR, Suguio K.

An Acad Bras Cienc. 2018 Apr-Jun;90(2):1369-1375. doi: 10.1590/0001-3765201820171010.

15.

The right compound for the right target: tackling RET.

Seoane J, Capdevila J.

Ann Oncol. 2018 Aug 1;29(8):1623-1625. doi: 10.1093/annonc/mdy188. No abstract available.

PMID:
29860429
16.

Uncertainty dimension and basin entropy in relativistic chaotic scattering.

Bernal JD, Seoane JM, Sanjuán MAF.

Phys Rev E. 2018 Apr;97(4-1):042214. doi: 10.1103/PhysRevE.97.042214.

PMID:
29758743
17.

Genetic heterogeneity and actionable mutations in HER2-positive primary breast cancers and their brain metastases.

De Mattos-Arruda L, Ng CKY, Piscuoglio S, Gonzalez-Cao M, Lim RS, De Filippo MR, Fusco N, Schultheis AM, Ortiz C, Viteri S, Arias A, Macedo GS, Oliveira M, Gomez P, Teixidó C, Nuciforo P, Peg V, Saura C, Ramon Y Cajal S, Casas FT, Weigelt B, Cortes J, Seoane J, Reis-Filho JS.

Oncotarget. 2018 Apr 17;9(29):20617-20630. doi: 10.18632/oncotarget.25041. eCollection 2018 Apr 17.

18.

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.

Mattos-Arruda L, Weigelt B, Cortes J, Won HH, Ng CKY, Nuciforo P, Bidard FC, Aura C, Saura C, Peg V, Piscuoglio S, Oliveira M, Smolders Y, Patel P, Norton L, Tabernero J, Berger MF, Seoane J, Reis-Filho JS.

Ann Oncol. 2018 Nov 1;29(11):2268. doi: 10.1093/annonc/mdx804. No abstract available.

PMID:
29718117
19.

Early evolutionary divergence between papillary and anaplastic thyroid cancers.

Capdevila J, Mayor R, Mancuso FM, Iglesias C, Caratù G, Matos I, Zafón C, Hernando J, Petit A, Nuciforo P, Cameselle-Teijeiro JM, Álvarez CV, Recio JA, Tabernero J, Matias-Guiu X, Vivancos A, Seoane J.

Ann Oncol. 2018 Jun 1;29(6):1454-1460. doi: 10.1093/annonc/mdy123.

PMID:
29648575
20.

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.

Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R; Cancer Genome Atlas Research Network, Thorsson V, Bass AJ, Laird PW.

Cancer Cell. 2018 Apr 9;33(4):721-735.e8. doi: 10.1016/j.ccell.2018.03.010. Epub 2018 Apr 2.

21.

Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid.

Martínez-Ricarte F, Mayor R, Martínez-Sáez E, Rubio-Pérez C, Pineda E, Cordero E, Cicuéndez M, Poca MA, López-Bigas N, Ramon Y Cajal S, Vieito M, Carles J, Tabernero J, Vivancos A, Gallego S, Graus F, Sahuquillo J, Seoane J.

Clin Cancer Res. 2018 Jun 15;24(12):2812-2819. doi: 10.1158/1078-0432.CCR-17-3800. Epub 2018 Apr 3.

22.

Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.

Rogers ZN, McFarland CD, Winters IP, Seoane JA, Brady JJ, Yoon S, Curtis C, Petrov DA, Winslow MM.

Nat Genet. 2018 Apr;50(4):483-486. doi: 10.1038/s41588-018-0083-2. Epub 2018 Apr 2.

23.

Shorter specialist time intervals are associated with advanced stage on symptomatic oral cancer.

Seoane J, Otero-Rico A, López-Cedrún JL, Varela-Centelles P.

Oral Dis. 2018 Mar;24(1-2):112-114. doi: 10.1111/odi.12754.

PMID:
29480638
24.

How will climate change affect endangered Mediterranean waterbirds?

Ramírez F, Rodríguez C, Seoane J, Figuerola J, Bustamante J.

PLoS One. 2018 Feb 13;13(2):e0192702. doi: 10.1371/journal.pone.0192702. eCollection 2018.

25.

Engineering Erg10 Thiolase from Saccharomyces cerevisiae as a Synthetic Toolkit for the Production of Branched-Chain Alcohols.

Torres-Salas P, Bernal V, López-Gallego F, Martínez-Crespo J, Sánchez-Murcia PA, Barrera V, Morales-Jiménez R, García-Sánchez A, Mañas-Fernández A, Seoane JM, Sagrera Polo M, Miranda JD, Calvo J, Huertas S, Torres JL, Alcalde-Bascones A, González-Barrera S, Gago F, Morreale A, González-Barroso MDM.

Biochemistry. 2018 Feb 27;57(8):1338-1348. doi: 10.1021/acs.biochem.7b01186. Epub 2018 Feb 6.

PMID:
29360348
26.

The European Society for Medical Oncology (ESMO) Precision Medicine Glossary.

Yates LR, Seoane J, Le Tourneau C, Siu LL, Marais R, Michiels S, Soria JC, Campbell P, Normanno N, Scarpa A, Reis-Filho JS, Rodon J, Swanton C, Andre F.

Ann Oncol. 2018 Jan 1;29(1):30-35. doi: 10.1093/annonc/mdx707.

PMID:
29140430
27.

A Dramatic Case of Odynophagia.

Sopeña B, Limeres J, García-Caballero L, Diniz-Freitas M, Seoane J, Diz P.

Dysphagia. 2018 Feb;33(1):133-135. doi: 10.1007/s00455-017-9861-8. Epub 2017 Nov 11.

PMID:
29128948
28.

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.

Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD.

Cancer Cell. 2017 Oct 9;32(4):460-473.e6. doi: 10.1016/j.ccell.2017.09.007.

29.

Interrogating open issues in cancer medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Sep 15;17(10):632. doi: 10.1038/nrc.2017.85. [Epub ahead of print]

PMID:
28912576
30.

An antisense oligonucleotide targeting TGF-β2 inhibits lung metastasis and induces CD86 expression in tumor-associated macrophages.

Huber-Ruano I, Raventós C, Cuartas I, Sánchez-Jaro C, Arias A, Parra JL, Wosikowski K, Janicot M, Seoane J.

Ann Oncol. 2017 Sep 1;28(9):2278-2285. doi: 10.1093/annonc/mdx314.

PMID:
28911087
31.

Cancer: Division hierarchy leads to cell heterogeneity.

Seoane J.

Nature. 2017 Sep 14;549(7671):164-166. doi: 10.1038/nature23546. Epub 2017 Aug 30. No abstract available.

PMID:
28854167
32.

Long-term safety and effectiveness of levodopa-carbidopa intestinal gel infusion.

De Fabregues O, Dot J, Abu-Suboh M, Hernández-Vara J, Ferré A, Romero O, Ibarria M, Seoane JL, Raguer N, Puiggros C, Gómez MR, Quintana M, Armengol JR, Alvarez-Sabín J.

Brain Behav. 2017 Jul 7;7(8):e00758. doi: 10.1002/brb3.758. eCollection 2017 Aug.

33.

The dose-dense principle in chemotherapy.

López ÁG, Iarosz KC, Batista AM, Seoane JM, Viana RL, Sanjuán MAF.

J Theor Biol. 2017 Oct 7;430:169-176. doi: 10.1016/j.jtbi.2017.07.003. Epub 2017 Jul 6.

PMID:
28689890
34.

The length of patient and primary care time interval in the pathways to treatment in symptomatic oral cancer. A quantitative systematic review.

Varela-Centelles P, Seoane J, Lopez-Cedrun JL, Fernandez-Sanroman J, García-Martin JM, Takkouche B, Alvarez-Novoa P, Seoane-Romero JM.

Clin Otolaryngol. 2018 Feb;43(1):164-171. doi: 10.1111/coa.12919. Epub 2017 Jul 24. Review.

PMID:
28627802
35.

Assessment of time intervals in the pathway to oral cancer diagnosis in north-westerm Spain. Relative contribution of patient interval.

Varela-Centelles P, López-Cedrún JL, Fernández-Santromán J, Álvarez-Nóvoa P, Luaces-Rey R, Pombo-Castro MJ, López-Jornet MP, Seoane J.

Med Oral Patol Oral Cir Bucal. 2017 Jul 1;22(4):e478-e483.

36.

Dynamics of the cell-mediated immune response to tumour growth.

López ÁG, Seoane JM, Sanjuán MAF.

Philos Trans A Math Phys Eng Sci. 2017 Jun 28;375(2096). pii: 20160291. doi: 10.1098/rsta.2016.0291.

37.

Species partitioning in a temperate mountain chain: Segregation by habitat vs. interspecific competition.

Bastianelli G, Wintle BA, Martin EH, Seoane J, Laiolo P.

Ecol Evol. 2017 Mar 19;7(8):2685-2696. doi: 10.1002/ece3.2883. eCollection 2017 Apr.

38.

Global relativistic effects in chaotic scattering.

Bernal JD, Seoane JM, Sanjuán MAF.

Phys Rev E. 2017 Mar;95(3-1):032205. doi: 10.1103/PhysRevE.95.032205. Epub 2017 Mar 8.

PMID:
28415234
39.

Surviving at high elevations: an inter- and intra-specific analysis in a mountain bird community.

Bastianelli G, Tavecchia G, Meléndez L, Seoane J, Obeso JR, Laiolo P.

Oecologia. 2017 Jun;184(2):293-303. doi: 10.1007/s00442-017-3852-1. Epub 2017 Mar 20.

PMID:
28321514
40.

TGF-β Family Signaling in Tumor Suppression and Cancer Progression.

Seoane J, Gomis RR.

Cold Spring Harb Perspect Biol. 2017 Dec 1;9(12). pii: a022277. doi: 10.1101/cshperspect.a022277. Review.

PMID:
28246180
41.

Is Periodontal Disease Associated with Alzheimer's Disease? A Systematic Review with Meta-Analysis.

Leira Y, Domínguez C, Seoane J, Seoane-Romero J, Pías-Peleteiro JM, Takkouche B, Blanco J, Aldrey JM.

Neuroepidemiology. 2017;48(1-2):21-31. doi: 10.1159/000458411. Epub 2017 Feb 21. Review.

PMID:
28219071
42.

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.

Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, Dane MA, Esch A, Feiler HS, Wang NJ, Hardwicke MA, Laquerre S, Jackson J, Wood KW, Weber B, Spellman PT, Aparicio S, Wooster R, Caldas C, Gray JW.

Breast Cancer Res. 2017 Feb 9;19(1):17. doi: 10.1186/s13058-017-0809-6. No abstract available.

43.

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Apr;17(4):254-268. doi: 10.1038/nrc.2016.140. Epub 2017 Jan 20. Review. Erratum in: Nat Rev Cancer. 2017 Sep 15;:.

44.

Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer.

Gueorguieva I, Cleverly A, Desaiah D, Azaro A, Seoane J, Braña I, Sicart E, Miles C, Lahn MM, Mitchell MI, Rodon J.

Drugs Context. 2016 Dec 2;5:212303. eCollection 2016.

45.

Diameter of alveolar antral artery in the lateral sinus wall: study of related factors.

Varela-Centelles P, Seoane J, Loira-Gago M, González-Mosquera A, Seoane-Romero JM.

Br J Oral Maxillofac Surg. 2017 May;55(4):413-415. doi: 10.1016/j.bjoms.2016.12.001. Epub 2016 Dec 13.

PMID:
27986307
46.

Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution.

Mundhada H, Seoane JM, Schneider K, Koza A, Christensen HB, Klein T, Phaneuf PV, Herrgard M, Feist AM, Nielsen AT.

Metab Eng. 2017 Jan;39:141-150. doi: 10.1016/j.ymben.2016.11.008. Epub 2016 Nov 29.

PMID:
27908688
47.

Distance of the alveolar antral artery from the alveolar crest. Related factors and surgical considerations in sinus floor elevation.

Varela-Centelles P, Loira-Gago M, Gonzalez-Mosquera A, Seoane-Romero JM, Garcia-Martin JM, Seoane J.

Med Oral Patol Oral Cir Bucal. 2016 Nov 1;21(6):e758-e765.

48.

Key points and time intervals for early diagnosis in symptomatic oral cancer: a systematic review.

Varela-Centelles P, López-Cedrún JL, Fernández-Sanromán J, Seoane-Romero JM, Santos de Melo N, Álvarez-Nóvoa P, Gómez I, Seoane J.

Int J Oral Maxillofac Surg. 2017 Jan;46(1):1-10. doi: 10.1016/j.ijom.2016.09.017. Epub 2016 Oct 15. Review.

PMID:
27751768
49.

Multi-omics Quantification of Species Variation of Escherichia coli Links Molecular Features with Strain Phenotypes.

Monk JM, Koza A, Campodonico MA, Machado D, Seoane JM, Palsson BO, Herrgård MJ, Feist AM.

Cell Syst. 2016 Sep 28;3(3):238-251.e12. doi: 10.1016/j.cels.2016.08.013. Epub 2016 Sep 22.

50.

The Taming of the TAMs.

Seoane J.

Trends Cell Biol. 2016 Aug;26(8):562-563. doi: 10.1016/j.tcb.2016.06.007. Epub 2016 Jul 6.

PMID:
27394965

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