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Items: 1 to 50 of 158

1.

Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET.

Nedelska Z, Senjem ML, Przybelski SA, Lesnick TG, Lowe VJ, Boeve BF, Arani A, Vemuri P, Graff-Radford J, Ferman TJ, Jones DT, Savica R, Knopman DS, Petersen RC, Jack CR, Kantarci K.

Neuroimage Clin. 2018 Jun 19;19:939-947. doi: 10.1016/j.nicl.2018.06.020. eCollection 2018.

PMID:
30003031
2.

Prosodic and phonetic subtypes of primary progressive apraxia of speech.

Utianski RL, Duffy JR, Clark HM, Strand EA, Botha H, Schwarz CG, Machulda MM, Senjem ML, Spychalla AJ, Jack CR Jr, Petersen RC, Lowe VJ, Whitwell JL, Josephs KA.

Brain Lang. 2018 Jul 3;184:54-65. doi: 10.1016/j.bandl.2018.06.004. [Epub ahead of print]

PMID:
29980072
3.

Tau Uptake in Agrammatic Primary Progressive Aphasia with and without Apraxia of Speech.

Utianski RL, Whitwell JL, Schwarz CG, Duffy JR, Botha H, Clark HM, Machulda MM, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Eur J Neurol. 2018 Jun 23. doi: 10.1111/ene.13733. [Epub ahead of print]

PMID:
29935044
4.

18F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus.

Townley RA, Botha H, Graff-Radford J, Boeve BF, Petersen RC, Senjem ML, Knopman DS, Lowe V, Jack CR Jr, Jones DT.

Neuroimage Clin. 2018 Feb 28;18:897-902. doi: 10.1016/j.nicl.2018.02.031. eCollection 2018.

5.

Non-right handed primary progressive apraxia of speech.

Botha H, Duffy JR, Whitwell JL, Strand EA, Machulda MM, Spychalla AJ, Tosakulwong N, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

J Neurol Sci. 2018 Jul 15;390:246-254. doi: 10.1016/j.jns.2018.05.007. Epub 2018 May 7.

PMID:
29801898
6.

Clinical and imaging progression over 10 years in a patient with primary progressive apraxia of speech and autopsy-confirmed corticobasal degeneration.

Tetzloff KA, Duffy JR, Strand EA, Machulda MM, Boland SM, Utianski RL, Botha H, Senjem ML, Schwarz CG, Josephs KA, Whitwell JL.

Neurocase. 2018 Apr;24(2):111-120. doi: 10.1080/13554794.2018.1477963. Epub 2018 May 25.

PMID:
29799310
7.

Elevated medial temporal lobe and pervasive brain tau-PET signal in normal participants.

Lowe VJ, Bruinsma TJ, Min HK, Lundt ES, Fang P, Senjem ML, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Schwarz CG, Knopman DS, Petersen RC, Jack CR Jr.

Alzheimers Dement (Amst). 2018 Feb 7;10:210-216. doi: 10.1016/j.dadm.2018.01.005. eCollection 2018.

8.

Considerations for Performing Level-2 Centiloid Transformations for Amyloid PET SUVR values.

Schwarz CG, Tosakulwong N, Senjem ML, Gunter JL, Therneau TM, Vemuri P, Lowe VJ, Jack CR Jr.

Sci Rep. 2018 May 9;8(1):7421. doi: 10.1038/s41598-018-25459-9.

9.

White matter reference region in PET studies of 11C-Pittsburgh Compound B uptake: effects of age and amyloid-β deposition.

Lowe VJ, Lundt ES, Senjem ML, Schwarz CG, Min HK, Przybelski SA, Kantarci K, Knopman D, Petersen RC, Jack CR Jr.

J Nucl Med. 2018 Apr 19. pii: jnumed.117.204271. doi: 10.2967/jnumed.117.204271. [Epub ahead of print]

PMID:
29674420
10.

Brain structure and cognition 3 years after the end of an early menopausal hormone therapy trial.

Kantarci K, Tosakulwong N, Lesnick TG, Zuk SM, Lowe VJ, Fields JA, Gunter JL, Senjem ML, Settell ML, Gleason CE, Shuster LT, Bailey KR, Dowling NM, Asthana S, Jack CR Jr, Rocca WA, Miller VM.

Neurology. 2018 Apr 17;90(16):e1404-e1412. doi: 10.1212/WNL.0000000000005325. Epub 2018 Mar 21.

11.

Regional Distribution, Asymmetry, and Clinical Correlates of Tau Uptake on [18F]AV-1451 PET in Atypical Alzheimer's Disease.

Tetzloff KA, Graff-Radford J, Martin PR, Tosakulwong N, Machulda MM, Duffy JR, Clark HM, Senjem ML, Schwarz CG, Spychalla AJ, Drubach DA, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.

J Alzheimers Dis. 2018;62(4):1713-1724. doi: 10.3233/JAD-170740.

PMID:
29614676
12.

Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease.

Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda MM, Senjem ML, Spychalla AJ, Vemuri P, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA.

Alzheimers Dement. 2018 Mar 30. pii: S1552-5260(18)30074-8. doi: 10.1016/j.jalz.2018.02.020. [Epub ahead of print]

PMID:
29605222
13.

Longitudinal tau PET in ageing and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, Machulda MM, Petersen RC.

Brain. 2018 May 1;141(5):1517-1528. doi: 10.1093/brain/awy059.

14.

[18F] AV-1451 uptake in corticobasal syndrome: the influence of beta-amyloid and clinical presentation.

Ali F, Whitwell JL, Martin PR, Senjem ML, Knopman DS, Jack CR, Lowe VJ, Petersen RC, Boeve BF, Josephs KA.

J Neurol. 2018 May;265(5):1079-1088. doi: 10.1007/s00415-018-8815-x. Epub 2018 Mar 1.

PMID:
29497818
15.

Joint associations of β-amyloidosis and cortical thickness with cognition.

Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC, Jack CR Jr.

Neurobiol Aging. 2018 May;65:121-131. doi: 10.1016/j.neurobiolaging.2018.01.017. Epub 2018 Feb 2.

PMID:
29471214
16.

[18 F]AV-1451 tau-PET and primary progressive aphasia.

Josephs KA, Martin PR, Botha H, Schwarz CG, Duffy JR, Clark HM, Machulda MM, Graff-Radford J, Weigand SD, Senjem ML, Utianski RL, Drubach DA, Boeve BF, Jones DT, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL.

Ann Neurol. 2018 Mar;83(3):599-611. doi: 10.1002/ana.25183. Epub 2018 Mar 13.

PMID:
29451323
17.

In vivo 18F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms.

Jones DT, Knopman DS, Graff-Radford J, Syrjanen JA, Senjem ML, Schwarz CG, Dheel C, Wszolek Z, Rademakers R, Kantarci K, Petersen RC, Jack CR Jr, Lowe VJ, Boeve BF.

Neurology. 2018 Mar 13;90(11):e947-e954. doi: 10.1212/WNL.0000000000005117. Epub 2018 Feb 9.

PMID:
29440563
18.

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia.

Botha H, Mantyh WG, Graff-Radford J, Machulda MM, Przybelski SA, Wiste HJ, Senjem ML, Parisi JE, Petersen RC, Murray ME, Boeve BF, Lowe VJ, Knopman DS, Jack CR Jr, Jones DT.

Neurology. 2018 Mar 13;90(11):e940-e946. doi: 10.1212/WNL.0000000000005124. Epub 2018 Feb 7.

PMID:
29438037
19.

Tau-PET imaging with [18F]AV-1451 in primary progressive apraxia of speech.

Utianski RL, Whitwell JL, Schwarz CG, Senjem ML, Tosakulwong N, Duffy JR, Clark HM, Machulda MM, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Cortex. 2018 Feb;99:358-374. doi: 10.1016/j.cortex.2017.12.021. Epub 2018 Jan 2.

PMID:
29353121
20.

[18 F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease.

Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda M, Senjem ML, Schwarz CG, Spychalla AJ, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA.

Ann Neurol. 2018 Feb;83(2):248-257. doi: 10.1002/ana.25142. Epub 2018 Feb 6.

PMID:
29323751
21.

Pittsburgh Compound B and AV-1451 positron emission tomography assessment of molecular pathologies of Alzheimer's disease in progressive supranuclear palsy.

Whitwell JL, Ahlskog JE, Tosakulwong N, Senjem ML, Spychalla AJ, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Parkinsonism Relat Disord. 2018 Mar;48:3-9. doi: 10.1016/j.parkreldis.2017.12.016. Epub 2017 Dec 13.

PMID:
29254665
22.

Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia.

Lowe VJ, Wiste HJ, Senjem ML, Weigand SD, Therneau TM, Boeve BF, Josephs KA, Fang P, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr.

Brain. 2018 Jan 1;141(1):271-287. doi: 10.1093/brain/awx320.

PMID:
29228201
23.

Longitudinal structural and molecular neuroimaging in agrammatic primary progressive aphasia.

Tetzloff KA, Duffy JR, Clark HM, Strand EA, Machulda MM, Schwarz CG, Senjem ML, Reid RI, Spychalla AJ, Tosakulwong N, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL.

Brain. 2018 Jan 1;141(1):302-317. doi: 10.1093/brain/awx293.

PMID:
29228180
24.

Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum.

Jones DT, Graff-Radford J, Lowe VJ, Wiste HJ, Gunter JL, Senjem ML, Botha H, Kantarci K, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr.

Cortex. 2017 Dec;97:143-159. doi: 10.1016/j.cortex.2017.09.018. Epub 2017 Oct 3.

25.

Predicting clinical decline in progressive agrammatic aphasia and apraxia of speech.

Whitwell JL, Weigand SD, Duffy JR, Clark HM, Strand EA, Machulda MM, Spychalla AJ, Senjem ML, Jack CR Jr, Josephs KA.

Neurology. 2017 Nov 28;89(22):2271-2279. doi: 10.1212/WNL.0000000000004685. Epub 2017 Nov 1.

PMID:
29093069
26.

Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study.

Josephs KA, Dickson DW, Tosakulwong N, Weigand SD, Murray ME, Petrucelli L, Liesinger AM, Senjem ML, Spychalla AJ, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Whitwell JL.

Lancet Neurol. 2017 Nov;16(11):917-924. doi: 10.1016/S1474-4422(17)30284-3. Epub 2017 Sep 11.

PMID:
28919059
27.

Comparison of [18F]Flutemetamol and [11C]Pittsburgh Compound-B in cognitively normal young, cognitively normal elderly, and Alzheimer's disease dementia individuals.

Lowe VJ, Lundt E, Knopman D, Senjem ML, Gunter JL, Schwarz CG, Kemp BJ, Jack CR Jr, Petersen RC.

Neuroimage Clin. 2017 Aug 14;16:295-302. doi: 10.1016/j.nicl.2017.08.011. eCollection 2017.

28.

Influence of preeclampsia and late-life hypertension on MRI measures of cortical atrophy.

Raman MR, Tosakulwong N, Zuk SM, Senjem ML, White WM, Fields JA, Mielke MM, Lesnick TG, Bailey KR, Jack CR Jr, Miller VM, Garovic VD, Kantarci K.

J Hypertens. 2017 Dec;35(12):2479-2485. doi: 10.1097/HJH.0000000000001492.

29.

White-matter integrity on DTI and the pathologic staging of Alzheimer's disease.

Kantarci K, Murray ME, Schwarz CG, Reid RI, Przybelski SA, Lesnick T, Zuk SM, Raman MR, Senjem ML, Gunter JL, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Dickson DW.

Neurobiol Aging. 2017 Aug;56:172-179. doi: 10.1016/j.neurobiolaging.2017.04.024. Epub 2017 May 4.

30.

Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis.

Zeydan B, Lowe VJ, Schwarz CG, Przybelski SA, Tosakulwong N, Zuk SM, Senjem ML, Gunter JL, Roberts RO, Mielke MM, Benarroch EE, Rodriguez M, Machulda MM, Lesnick TG, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Kantarci OH.

Mult Scler. 2018 May;24(6):739-749. doi: 10.1177/1352458517707346. Epub 2017 May 5.

PMID:
28474977
31.

Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC.

Lancet Neurol. 2017 Jun;16(6):435-444. doi: 10.1016/S1474-4422(17)30077-7. Epub 2017 Apr 26.

32.

Contributions of imprecision in PET-MRI rigid registration to imprecision in amyloid PET SUVR measurements.

Schwarz CG, Jones DT, Gunter JL, Lowe VJ, Vemuri P, Senjem ML, Petersen RC, Knopman DS, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative.

Hum Brain Mapp. 2017 Apr 22. doi: 10.1002/hbm.23622. [Epub ahead of print]

33.

Aortic hemodynamics and white matter hyperintensities in normotensive postmenopausal women.

Barnes JN, Harvey RE, Zuk SM, Lundt ES, Lesnick TG, Gunter JL, Senjem ML, Shuster LT, Miller VM, Jack CR Jr, Joyner MJ, Kantarci K.

J Neurol. 2017 May;264(5):938-945. doi: 10.1007/s00415-017-8476-1. Epub 2017 Apr 7.

34.

Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition.

Vemuri P, Lowe VJ, Knopman DS, Senjem ML, Kemp BJ, Schwarz CG, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr.

Alzheimers Dement (Amst). 2016 Dec 21;6:21-30. doi: 10.1016/j.dadm.2016.12.010. eCollection 2017.

35.

A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity.

Schwarz CG, Gunter JL, Wiste HJ, Przybelski SA, Weigand SD, Ward CP, Senjem ML, Vemuri P, Murray ME, Dickson DW, Parisi JE, Kantarci K, Weiner MW, Petersen RC, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2016 May 30;11:802-812. doi: 10.1016/j.nicl.2016.05.017. eCollection 2016.

36.

AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies.

Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Lesnick TG, Spychalla AJ, Gunter JL, Fields JA, Graff-Radford J, Ferman TJ, Jones DT, Murray ME, Knopman DS, Jack CR Jr, Petersen RC.

Ann Neurol. 2017 Jan;81(1):58-67. doi: 10.1002/ana.24825. Epub 2016 Dec 19.

37.

Varying Degrees of Temporoparietal Hypometabolism on FDG-PET Reveal Amyloid-Positive Logopenic Primary Progressive Aphasia is not a Homogeneous Clinical Entity.

Krishnan K, Machulda MM, Whitwell JL, Butts AM, Duffy JR, Strand EA, Senjem ML, Spychalla AJ, Jack CR, Lowe VJ, Josephs KA.

J Alzheimers Dis. 2017;55(3):1019-1029.

38.

Defining imaging biomarker cut points for brain aging and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC.

Alzheimers Dement. 2017 Mar;13(3):205-216. doi: 10.1016/j.jalz.2016.08.005. Epub 2016 Sep 30.

39.

[18 F]AV-1451 tau positron emission tomography in progressive supranuclear palsy.

Whitwell JL, Lowe VJ, Tosakulwong N, Weigand SD, Senjem ML, Schwarz CG, Spychalla AJ, Petersen RC, Jack CR Jr, Josephs KA.

Mov Disord. 2017 Jan;32(1):124-133. doi: 10.1002/mds.26834. Epub 2016 Oct 27.

40.

Tracking the development of agrammatic aphasia: A tensor-based morphometry study.

Whitwell JL, Duffy JR, Machulda MM, Clark HM, Strand EA, Senjem ML, Gunter JL, Spychalla AJ, Petersen RC, Jack CR Jr, Josephs KA.

Cortex. 2017 May;90:138-148. doi: 10.1016/j.cortex.2016.09.017. Epub 2016 Sep 30.

41.

Optimizing PiB-PET SUVR change-over-time measurement by a large-scale analysis of longitudinal reliability, plausibility, separability, and correlation with MMSE.

Schwarz CG, Senjem ML, Gunter JL, Tosakulwong N, Weigand SD, Kemp BJ, Spychalla AJ, Vemuri P, Petersen RC, Lowe VJ, Jack CR Jr.

Neuroimage. 2017 Jan 1;144(Pt A):113-127. doi: 10.1016/j.neuroimage.2016.08.056. Epub 2016 Aug 27.

42.

18F-FDG PET in Posterior Cortical Atrophy and Dementia with Lewy Bodies.

Whitwell JL, Graff-Radford J, Singh TD, Drubach DA, Senjem ML, Spychalla AJ, Tosakulwong N, Lowe VJ, Josephs KA.

J Nucl Med. 2017 Apr;58(4):632-638. doi: 10.2967/jnumed.116.179903. Epub 2016 Sep 29.

43.

[18F]AV-1451 tau-PET uptake does correlate with quantitatively measured 4R-tau burden in autopsy-confirmed corticobasal degeneration.

Josephs KA, Whitwell JL, Tacik P, Duffy JR, Senjem ML, Tosakulwong N, Jack CR, Lowe V, Dickson DW, Murray ME.

Acta Neuropathol. 2016 Dec;132(6):931-933. Epub 2016 Sep 19. No abstract available.

44.

Effects of hormone therapy on brain structure: A randomized controlled trial.

Kantarci K, Tosakulwong N, Lesnick TG, Zuk SM, Gunter JL, Gleason CE, Wharton W, Dowling NM, Vemuri P, Senjem ML, Shuster LT, Bailey KR, Rocca WA, Jack CR Jr, Asthana S, Miller VM.

Neurology. 2016 Aug 30;87(9):887-96. doi: 10.1212/WNL.0000000000002970. Epub 2016 Jul 29.

45.

Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum.

Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC.

Neurobiol Aging. 2016 Oct;46:32-42. doi: 10.1016/j.neurobiolaging.2016.06.003. Epub 2016 Jun 16.

46.

Amyloid-β deposition and regional grey matter atrophy rates in dementia with Lewy bodies.

Sarro L, Senjem ML, Lundt ES, Przybelski SA, Lesnick TG, Graff-Radford J, Boeve BF, Lowe VJ, Ferman TJ, Knopman DS, Comi G, Filippi M, Petersen RC, Jack CR Jr, Kantarci K.

Brain. 2016 Oct;139(Pt 10):2740-2750. Epub 2016 Jul 24.

47.

Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia.

Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC.

Neurology. 2016 Aug 16;87(7):691-8. doi: 10.1212/WNL.0000000000002979. Epub 2016 Jul 15.

48.

Predicting Survival in Dementia With Lewy Bodies With Hippocampal Volumetry.

Graff-Radford J, Lesnick TG, Boeve BF, Przybelski SA, Jones DT, Senjem ML, Gunter JL, Ferman TJ, Knopman DS, Murray ME, Dickson DW, Sarro L, Jack CR Jr, Petersen RC, Kantarci K.

Mov Disord. 2016 Jul;31(7):989-94. doi: 10.1002/mds.26666. Epub 2016 May 23.

49.

Early Postmenopausal Transdermal 17β-Estradiol Therapy and Amyloid-β Deposition.

Kantarci K, Lowe VJ, Lesnick TG, Tosakulwong N, Bailey KR, Fields JA, Shuster LT, Zuk SM, Senjem ML, Mielke MM, Gleason C, Jack CR, Rocca WA, Miller VM.

J Alzheimers Dis. 2016 May 7;53(2):547-56. doi: 10.3233/JAD-160258.

50.

Clinical correlates of longitudinal brain atrophy in progressive supranuclear palsy.

Tsai RM, Lobach I, Bang J, Whitwell JL, Senjem ML, Jack CR Jr, Rosen H, Miller B, Boxer AL; AL-108-231 Investigators.

Parkinsonism Relat Disord. 2016 Jul;28:29-35. doi: 10.1016/j.parkreldis.2016.04.006. Epub 2016 Apr 24.

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