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Items: 37

1.

Human placental villi contain stromal macrovesicles associated with networks of stellate cells.

Palaiologou E, Etter O, Goggin P, Chatelet DS, Johnston DA, Lofthouse EM, Doherty R, Pearson-Farr J, Sengers BG, Torrens C, Cleal JK, Page AM, Lewis RM.

J Anat. 2020 Jan;236(1):132-141. doi: 10.1111/joa.13082. Epub 2019 Sep 11.

2.

In vivo kinetic study of materno-fetal fatty acid transfer in obese and normal weight pregnant women.

Gázquez A, Prieto-Sánchez MT, Blanco-Carnero JE, van Harskamp D, Perazzolo S, Oosterink JE, Demmelmair H, Schierbeek H, Sengers BG, Lewis RM, van Goudoever JB, Koletzko B, Larqué E.

J Physiol. 2019 Oct;597(19):4959-4973. doi: 10.1113/JP278146. Epub 2019 Jul 24.

PMID:
31287560
3.

Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta.

Lofthouse EM, Torrens C, Manousopoulou A, Nahar M, Cleal JK, O'Kelly IM, Sengers BG, Garbis SD, Lewis RM.

FASEB J. 2019 Jul;33(7):8211-8220. doi: 10.1096/fj.201900015RR. Epub 2019 Mar 28.

4.

Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux.

Lofthouse EM, Cleal JK, O'Kelly IM, Sengers BG, Lewis RM.

Biochem Biophys Res Commun. 2018 Nov 17;506(1):237-242. doi: 10.1016/j.bbrc.2018.10.074. Epub 2018 Oct 19.

5.

A systems perspective on placental amino acid transport.

Cleal JK, Lofthouse EM, Sengers BG, Lewis RM.

J Physiol. 2018 Dec;596(23):5511-5522. doi: 10.1113/JP274883. Epub 2018 Sep 7. Review.

6.

Collective Cell Behavior in Mechanosensing of Substrate Thickness.

Tusan CG, Man YH, Zarkoob H, Johnston DA, Andriotis OG, Thurner PJ, Yang S, Sander EA, Gentleman E, Sengers BG, Evans ND.

Biophys J. 2018 Jun 5;114(11):2743-2755. doi: 10.1016/j.bpj.2018.03.037.

7.

Modelling the effect of intervillous flow on solute transfer based on 3D imaging of the human placental microstructure.

Perazzolo S, Lewis RM, Sengers BG.

Placenta. 2017 Dec;60:21-27. doi: 10.1016/j.placenta.2017.10.003. Epub 2017 Oct 12.

PMID:
29208235
8.

Transfer and Metabolism of Cortisol by the Isolated Perfused Human Placenta.

Stirrat LI, Sengers BG, Norman JE, Homer NZM, Andrew R, Lewis RM, Reynolds RM.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):640-648. doi: 10.1210/jc.2017-02140.

9.

Serial block-face scanning electron microscopy of erythrocytes protruding through the human placental syncytiotrophoblast.

Palaiologou E, Goggin P, Chatelet DS, Lofthouse EM, Torrens C, Sengers BG, Cleal JK, Page A, Lewis RM.

J Anat. 2017 Oct;231(4):634-637. doi: 10.1111/joa.12658. Epub 2017 Jul 17.

10.

Modelling nutrient transfer based on 3D imaging of the human placental microstructure.

Perazzolo S, Lewis RM, Sengers BG.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:5953-5956. doi: 10.1109/EMBC.2016.7592084.

PMID:
28269608
11.

The influence of placental metabolism on fatty acid transfer to the fetus.

Perazzolo S, Hirschmugl B, Wadsack C, Desoye G, Lewis RM, Sengers BG.

J Lipid Res. 2017 Feb;58(2):443-454. doi: 10.1194/jlr.P072355. Epub 2016 Dec 2.

12.

Modeling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion.

Sengers BG, McGinty S, Nouri FZ, Argungu M, Hawkins E, Hadji A, Weber A, Taylor A, Sepp A.

MAbs. 2016 Jul;8(5):905-15. doi: 10.1080/19420862.2016.1178437. Epub 2016 Apr 20.

13.

Computational modelling of placental amino acid transfer as an integrated system.

Panitchob N, Widdows KL, Crocker IP, Johnstone ED, Please CP, Sibley CP, Glazier JD, Lewis RM, Sengers BG.

Biochim Biophys Acta. 2016 Jul;1858(7 Pt A):1451-61. doi: 10.1016/j.bbamem.2016.03.028. Epub 2016 Apr 2.

14.

Nanofibrous poly(3-hydroxybutyrate)/poly(3-hydroxyoctanoate) scaffolds provide a functional microenvironment for cartilage repair.

Ching KY, Andriotis OG, Li S, Basnett P, Su B, Roy I, Tare RS, Sengers BG, Stolz M.

J Biomater Appl. 2016 Jul;31(1):77-91. doi: 10.1177/0885328216639749. Epub 2016 Mar 23.

PMID:
27013217
15.

Computational modelling of fatty acid transport in the human placenta.

Perazzolo S, Hirschmugl B, Wadsack C, Desoye G, Lewis RM, Sengers BG.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:8054-7. doi: 10.1109/EMBC.2015.7320262.

PMID:
26738162
16.

Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation.

Lofthouse EM, Perazzolo S, Brooks S, Crocker IP, Glazier JD, Johnstone ED, Panitchob N, Sibley CP, Widdows KL, Sengers BG, Lewis RM.

Am J Physiol Regul Integr Comp Physiol. 2016 Feb 1;310(9):R828-36. doi: 10.1152/ajpregu.00405.2015. Epub 2015 Dec 16.

17.

Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms.

Widdows KL, Panitchob N, Crocker IP, Please CP, Hanson MA, Sibley CP, Johnstone ED, Sengers BG, Lewis RM, Glazier JD.

FASEB J. 2015 Jun;29(6):2583-94. doi: 10.1096/fj.14-267773. Epub 2015 Mar 11.

18.

Computational modelling of amino acid exchange and facilitated transport in placental membrane vesicles.

Panitchob N, Widdows KL, Crocker IP, Hanson MA, Johnstone ED, Please CP, Sibley CP, Glazier JD, Lewis RM, Sengers BG.

J Theor Biol. 2015 Jan 21;365:352-64. doi: 10.1016/j.jtbi.2014.10.042. Epub 2014 Nov 11.

19.

Chondrogenic potential of human articular chondrocytes and skeletal stem cells: a comparative study.

Li S, Sengers BG, Oreffo RO, Tare RS.

J Biomater Appl. 2015 Jan;29(6):824-36. doi: 10.1177/0885328214548604. Epub 2014 Aug 20.

20.

The effect of oxygen tension on human articular chondrocyte matrix synthesis: integration of experimental and computational approaches.

Li S, Oreffo RO, Sengers BG, Tare RS.

Biotechnol Bioeng. 2014 Sep;111(9):1876-85. doi: 10.1002/bit.25241. Epub 2014 May 5.

21.

Pore geometry regulates early stage human bone marrow cell tissue formation and organisation.

Knychala J, Bouropoulos N, Catt CJ, Katsamenis OL, Please CP, Sengers BG.

Ann Biomed Eng. 2013 May;41(5):917-30. doi: 10.1007/s10439-013-0748-z. Epub 2013 Feb 13.

PMID:
23404072
22.

Review: Modelling placental amino acid transfer--from transporters to placental function.

Lewis RM, Brooks S, Crocker IP, Glazier J, Hanson MA, Johnstone ED, Panitchob N, Please CP, Sibley CP, Widdows KL, Sengers BG.

Placenta. 2013 Mar;34 Suppl:S46-51. doi: 10.1016/j.placenta.2012.10.010. Epub 2012 Nov 24. Review.

23.

Tantalum trabecular metal - addition of human skeletal cells to enhance bone implant interface strength and clinical application.

Smith JO, Sengers BG, Aarvold A, Tayton ER, Dunlop DG, Oreffo RO.

J Tissue Eng Regen Med. 2014 Apr;8(4):304-13. doi: 10.1002/term.1525. Epub 2012 Jun 4.

PMID:
22674820
24.

Mathematical modelling of tissue formation in chondrocyte filter cultures.

Catt CJ, Schuurman W, Sengers BG, van Weeren PR, Dhert WJ, Please CP, Malda J.

Eur Cell Mater. 2011 Dec 17;22:377-92.

25.

Computational modelling of amino acid transfer interactions in the placenta.

Sengers BG, Please CP, Lewis RM.

Exp Physiol. 2010 Jul;95(7):829-40. doi: 10.1113/expphysiol.2010.052902. Epub 2010 Apr 23.

26.

Characterisation of human bone marrow stromal cell heterogeneity for skeletal regeneration strategies using a two-stage colony assay and computational modelling.

Sengers BG, Dawson JI, Oreffo RO.

Bone. 2010 Feb;46(2):496-503. doi: 10.1016/j.bone.2009.10.002. Epub 2009 Oct 8.

PMID:
19818885
27.

Design criteria for a printed tissue engineering construct: a mathematical homogenization approach.

Shipley RJ, Jones GW, Dyson RJ, Sengers BG, Bailey CL, Catt CJ, Please CP, Malda J.

J Theor Biol. 2009 Aug 7;259(3):489-502. doi: 10.1016/j.jtbi.2009.03.037. Epub 2009 Apr 8.

PMID:
19361531
28.

Experimental-computational evaluation of human bone marrow stromal cell spreading on trabecular bone structures.

Sengers BG, Please CP, Taylor M, Oreffo RO.

Ann Biomed Eng. 2009 Jun;37(6):1165-76. doi: 10.1007/s10439-009-9676-3. Epub 2009 Mar 19.

PMID:
19296221
29.
30.

Computational modelling of cell spreading and tissue regeneration in porous scaffolds.

Sengers BG, Taylor M, Please CP, Oreffo RO.

Biomaterials. 2007 Apr;28(10):1926-40. Epub 2006 Dec 18. Review.

PMID:
17178156
31.

Computational modeling to predict the temporal regulation of chondrocyte metabolism in response to various dynamic compression regimens.

Sengers BG, Oomens CW, Nguyen TQ, Bader DL.

Biomech Model Mechanobiol. 2006 Jun;5(2-3):111-22. Epub 2006 Mar 3.

PMID:
16514518
32.

Can the growth factors PTHrP, Ihh and VEGF, together regulate the development of a long bone?

Brouwers JE, van Donkelaar CC, Sengers BG, Huiskes R.

J Biomech. 2006;39(15):2774-82. Epub 2005 Nov 18.

PMID:
16298375
33.

Nutrient utilization by bovine articular chondrocytes: a combined experimental and theoretical approach.

Sengers BG, Heywood HK, Lee DA, Oomens CW, Bader DL.

J Biomech Eng. 2005 Oct;127(5):758-66.

PMID:
16248305
34.

Computational study of culture conditions and nutrient supply in cartilage tissue engineering.

Sengers BG, van Donkelaar CC, Oomens CW, Baaijens FP.

Biotechnol Prog. 2005 Jul-Aug;21(4):1252-61.

PMID:
16080709
35.

The local matrix distribution and the functional development of tissue engineered cartilage, a finite element study.

Sengers BG, Van Donkelaar CC, Oomens CW, Baaijens FP.

Ann Biomed Eng. 2004 Dec;32(12):1718-27.

PMID:
15675683
36.

An integrated finite-element approach to mechanics, transport and biosynthesis in tissue engineering.

Sengers BG, Oomens CW, Baaijens FP.

J Biomech Eng. 2004 Feb;126(1):82-91.

PMID:
15171133
37.

Predicting local cell deformations in engineered tissue constructs: a multilevel finite element approach.

Breuls RG, Sengers BG, Oomens CW, Bouten CV, Baaijens FP.

J Biomech Eng. 2002 Apr;124(2):198-207.

PMID:
12002129

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